Neural Mechanisms of Interference Control and Time Discrimination in Attention-Deficit/Hyperactivity Disorder

Journal of the American Academy of Child and Adolescent Psychiatry

Volumn 49, Issue 4, 2010, Pages 356-367

  Vloet, Timo D ^a,c   Gilsbach, Susanne ^a,c   Neufang, Susanne ^a,c   Fink, Gereon R ^a,b   Herpertz Dahlmann, Beate ^c   Konrad, Kerstin ^a,c  

^a FORSCHUNGSZENTRUM JÜLICH   (Germany)

^b UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^c RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

ADHD; executive functions; fMRI; functional connectivity; time discrimination

Indexed keywords

ADOLESCENT; ARTICLE; ATTENTION DEFICIT DISORDER; BRAIN FUNCTION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; EXPERIMENTAL DESIGN; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; MALE; MENTAL FUNCTION; NERVE CONDUCTION; NEUROPSYCHOLOGICAL TEST; PRIORITY JOURNAL; PSYCHOLOGIC ASSESSMENT; PSYCHOPHYSIOLOGY; SCHOOL CHILD; TIME PERCEPTION;

ADOLESCENT; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CEREBELLUM; CHILD; EXECUTIVE FUNCTION; FRONTAL LOBE; HUMANS; MAGNETIC RESONANCE IMAGING; NEURAL PATHWAYS; PARIETAL LOBE; PUTAMEN; TASK PERFORMANCE AND ANALYSIS; TIME PERCEPTION;

EID: 77949656336     PISSN: 08908567     EISSN: 15275418     Source Type: Journal    
DOI: 10.1097/00004583-201004000-00010     Document Type: Article

References (44)

1. Nigg J.T. Is ADHD a disinhibitory disorder?. Psychol Bull. 127 (2001) 571-598
2. Durston S., and Casey B.J. What have we learned about cognitive development from neuroimaging?. Neuropsychologia 44 (2006) 2149-2157
3. Konrad K., Neufang S., Hanisch C., Fink G.R., and Herpertz-Dahlmann B. Dysfunctional attentional networks in children with ADHD: evidence from an event-related fMRI-study. Biol Psychiatry 59 (2006) 643-651
4. Smith A.B., Taylor E., Brammer M., Toone B., and Rubia K. Task-specific hypoactivation in prefrontal and temporo-parietal brain regions during motor inhibition and task switching in mediaction-naïve children and adolescents with ADHD. Am J Psychiatry 163 (2006) 1044-1051
5. Vaidya C.J., Bunge S.A., Dudukovic N.M., et al. Altered neural substrates of cognitive control in childhood ADHD: evidence from fMRI. Am J Psychiatry 162 (2005) 1605-1613
6. Toplak M.E., Dockstader C., and Tannock R. Temporal information processing in ADHD: findings to date and new methods. J Neurosci Methods 151 (2006) 15-29
7. Mullins C., Bellgrove M.A., Gill M., and Robertson I.H. Variability in time-reproduction: difference in ADHD combined and inattentive subtypes. Am Acad Child Adolesc Psychiatry 44 (2005) 169-176
8. Barkley R.A. ADHD, self-regulation, and time: towards a more comprehensive theory. J Dev Behav Pediatr. 18 (1997) 271-279
9. Rubia K., Halari R., Christakou A., and Taylor E. Impulsiveness as a timing disturbance: neurocognitive abnormalities in ADHD during temporal processes and normalization with methylphenidate. Philos Trans R Soc Lond B Biol Sci. 364; (2009) 1919-1931
10. Adleman N.E., Menon V., Blasey C.M., et al. A developmental fMRI study of the Stroop-color-word task. Neuroimage 16 (2002) 61-75
11. Rao S.M., Mayer A.R., and Harrington D.L. The evolution of brain activation during temporal processing. Nat Neurosci. 4 (2001) 317-323
12. Harrington D.L., and Haaland K.Y. Neural underpinnings of temporal processing: a review of focal lesion, pharmacological, and functional imaging research. Rev Neurosci. 10 (1999) 91-116
13. Ivry R.B., and Spencer R.M. The neural representation of time. Curr Opin Neurobiol. 14 (2004) 225-232
14. Fraisse P. Perception and estimation of time. Ann Rev Psychol. 35 (1984) 1-36
15. Buhusi C.V., and Meck W.H. What makes us tick?. Functional and neural mechanisms of interval timing. Nat Rev Neurosci. 6 (2005) 755-765
16. Toplak M.E., Rucklidge J.J., Hetherington R., John S.C.F., and Tannock R. Time-perception deficits in ADHD and comorbid reading difficulties in child and adolescent samples. J Child Psychol Psychiatry 44 (2003) 888-903
17. Durston S., Hulshoff-Pol H.E., Schnack H.G., et al. Magnetic resonance imaging of boys with ADHD and their unaffected siblings. J Am Acad Child Adolesc Psychiaty 43 (2004) 332-340
18. Durston S., Fossella J.A., Mulder M.J., et al. Dopamine-transporter genotype conveys familial risk of ADHD through striatal activation. J Am Acad Child Adolesc Psychiatry 47 (2008) 61-67
19. Konrad K., Neufang S., Fink G.R., and Herpertz-Dahlmann B. Long-term effects of methylphenidate on neural networks associated with executive attention in children with ADHD: results from a longitudinal fMRI study. J Am Acad Child Adolesc Psychiatry 46 (2007) 1633-1641
20. Smith A.B., Taylor E., Brammer M., Halari R., and Rubia K. Reduced activation in right lateral-prefrontal cortex and anterior cingulated gyrus in medication-naïve adolescents with ADHD during time discrimination. J Child Psychol Psychiatry 49 (2008) 977-985
21. Wang L., Zhu C., He Y., et al. Altered small-world brain functional networks in children with ADHD. Hum Brain Mapp. 30 (2009) 638-649
22. Castellanos F.X., Margulies D.S., Kelly C., et al. Cingulate-precuneus interactions: a new locus of dysfunction in adult ADHD. Biol Psychiatry 63 (2008) 332-337
23. Wolf R.C., Plichta M.M., Sambataro F., et al. Regional brain activation changes and abnormal functional connectivity of the ventro-lateral prefrontal cortex during working memory processing in adults with ADHD. Hum Brain Mapp. 30 (2009) 2252-2266
24. Neufang S., Fink G.R., Herpertz-Dahlmann B., and Konrad K. Developmental changes in neural activation and psychophysiological interaction patterns of brain regions associated with interference control and time-perception. Neuroimage 43 (2008) 399-409
25. th ed. (2001), Department of Child and Adolescent Psychiatry, Frankfurt
26. Tewes U., Rossmann P., and Schallberger U. Hamburg-Wechsler-Intelligenztest für Kinder (HAWIK-IIIR) (1999), Huber, Bern
27. Oldfield R.C. The assessment and analysis of handedness: the Edinburgh-Inventory. Neuropsychologia 9 (1971) 97-113
28. Semrud-Clikeman M., Pliszka S., and Liotti M. Executive functioning in children with ADHD: combined type with and without a stimulant medication history. Neuropsychology 22 (2008) 329-340
29. Pliszka S.R., Glahn D.C., Semrud-Clikeman M., et al. Neuroimaging of inhibitory control areas in children with ADHD who were treatment naive or in long-term treatment. Am J Psychiatry 63 (2006) 1052-1060
30. Smith A., Taylor E., Lidzba K., and Rubia K. A right hemispheric fronto-cerebellar network for time-discrimination of several hundreds of milliseconds. Neuroimage 20 (2003) 344-350
31. Davidson M.C., Amso D., Anderson L.C., and Diamond A. Development of cognitive control and executive functions from 4-13 years: evidence from manipulations of memory, inhibition, and task switching. Neuropsychologia 44 (2006) 2037-2078
32. Casey B.J., Thomas K.M., Tomihisa F.W., et al. Dissociation of response conflict, attentional selection, and expectancy with functional magnetic resonance imaging. Proc Natl Acad Sci USA 97 (2000) 8728-8733
33. Friston K.J., Buechel C., Fink G.R., et al. Psychophysiological and modulatory interactions in neuroimaging. Neuroimage 6 (1997) 218-229
34. Friston K.J., Holmes A.P., Poline J.B., et al. Analysis of fMRI time-series revisited. Neuroimage 2 (1995) 45-53
35. Poline J.B., Worsley K.J., Evans A.C., and Friston K.J. Combining spatial extent and peak intensity to test for activations in functional imaging. Neuroimage 5 (1997) 83-96
36. Eickhoff S.B., Stepan K.E., Mohlberg H., et al. A new SPM Toolbox for combining probabilistic cytoarchitectonic maps and functional imaging data. Neuroimage 25 (2005) 1325-1335
37. Maldjian J.A., Laurienti P.J., Kraft R.A., and Burdette J.H. An automated method for neuroanatomic cytoarchitectonic atlas-based interrogation of fMRI data sets. Neuroimage 19 (2003) 1233-1239
38. Nichols T., Brett M., Andersson J., Wager T., and Poline J.B. Valid conjunction interference with the minimum statistic. Neuroimage 25 (2005) 653-660
39. Booth J.R., Burman D.D., Meyer J.R., et al. Neural development of selective attention and response inhibition. Neuroimage 20 (2003) 737-751
40. Rubia K., Smith A.B., Woolley J., et al. Progressive increase of fronto-striatal brain activation from childhood to adulthood during event-related tasks of cognitive control. Hum Brain Mapp. 27 (2006) 973-993
41. Mulder M.J., Baeyens D., Davidson M.C., et al. Familial vulnerability to ADHD affects activity in the cerebellum in addition to the prefrontal systems. J Am Acad Child Adolesc Psychiatry 47 (2008) 68-75
42. Casey B.J., Epstein J.N., Buhle J., et al. Fronto-striatal connectivity and its role in cognitive control in parent-child dyads with ADHD. Am J Psychiatry 164 (2007) 1729-1736
43. Fink G.R., Marshall J.C., Weiss P.H., Toni I., and Zilles K. Task instructions influence the cognitive strategies involved in line bisection judgements: evidence from modulated neural mechanisms revealed by fMRI. Neuropsychologia 40 (2002) 119-130
44. Fair D.A., Dosenbach N.U., Church J.A., et al. Development of distinct control networks through segregation and integration. Proc Natl Acad Sci USA 104 (2007) 13507-13512