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Volumn 67, Issue 5, 2010, Pages 351-360

Clevidipine: A new intravenous option for the management of acute hypertension

Author keywords

Clevidipine butyrate; Dosage; Drug administration routes; Half life; Hypertension; Hypotensive agents; Mechanism of action; Metabolism; Pharmacokinetics; Toxicity

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM ION; CLEVIDIPINE; CYTOCHROME P450 INHIBITOR; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GLYCERYL TRINITRATE; LABETALOL; NICARDIPINE; NITROPRUSSIDE SODIUM;

EID: 77949652037     PISSN: 10792082     EISSN: None     Source Type: Journal    
DOI: 10.2146/ajhp080692     Document Type: Review
Times cited : (14)

References (28)
  • 1
    • 0038460302 scopus 로고    scopus 로고
    • Chobanian AV, Bakris GL, Black HR et al. The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA. 2003; 289:2560-72. [Erratum, JAMA. 2003; 290:197.]
    • Chobanian AV, Bakris GL, Black HR et al. The seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA. 2003; 289:2560-72. [Erratum, JAMA. 2003; 290:197.]
  • 2
    • 33846857559 scopus 로고    scopus 로고
    • Rosamond W, Flegal K, Friday G et al. Heart disease and stroke statistics: 2007 update. A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2007; 115:e69-171. [Erratum, Circulation. 2007; 115:e172.]
    • Rosamond W, Flegal K, Friday G et al. Heart disease and stroke statistics: 2007 update. A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2007; 115:e69-171. [Erratum, Circulation. 2007; 115:e172.]
  • 3
    • 34250885768 scopus 로고    scopus 로고
    • Marik PE, Varon J. Hypertensive crises: challenges and management. Chest. 2007; 131:1949-62. [Erratum, Chest. 2007; 132:1721.]
    • Marik PE, Varon J. Hypertensive crises: challenges and management. Chest. 2007; 131:1949-62. [Erratum, Chest. 2007; 132:1721.]
  • 4
    • 38949211561 scopus 로고    scopus 로고
    • Treatment of acute severe hypertension: Current and newer agents
    • Varon J. Treatment of acute severe hypertension: current and newer agents. Drugs. 2008; 68:283-97.
    • (2008) Drugs , vol.68 , pp. 283-297
    • Varon, J.1
  • 5
    • 77949591331 scopus 로고    scopus 로고
    • Approval letter for Cleviprex (clevidipine butyrate)
    • accessed 2009 Nov 23
    • Food and Drug Administration. Approval letter for Cleviprex (clevidipine butyrate). NDA approval letter. www.accessdata.fda.gov/drugsatfda-docs/nda/2008/ 022156s000-Approv.pdf (accessed 2009 Nov 23).
    • NDA approval letter
  • 6
    • 49849098985 scopus 로고    scopus 로고
    • Treatment of acute postoperative hypertension in cardiac surgery patients: An Efficacy Study of Clevidipine Assessing its Postoperative Anti-hypertensive Effect in Cardiac Sugery-2 (ESCAPE-2), a randomized, double-blind, placebo-controlled trial
    • Singla N, Warltier DC. Treatment of acute postoperative hypertension in cardiac surgery patients: an Efficacy Study of Clevidipine Assessing its Postoperative Anti-hypertensive Effect in Cardiac Sugery-2 (ESCAPE-2), a randomized, double-blind, placebo-controlled trial. Anesth Analg. 2008; 107:59-67.
    • (2008) Anesth Analg , vol.107 , pp. 59-67
    • Singla, N.1    Warltier, D.C.2
  • 7
    • 36549019202 scopus 로고    scopus 로고
    • Hypertensive urgency and emergency
    • Mar
    • Vaidya CK, Ouellette JR. Hypertensive urgency and emergency. Hosp Physician. 2007;43(Mar):43-50.
    • Hosp Physician , vol.2007 , Issue.43 , pp. 43-50
    • Vaidya, C.K.1    Ouellette, J.R.2
  • 8
    • 0030695126 scopus 로고    scopus 로고
    • Diversity of calcium antagonists
    • Pitt B. Diversity of calcium antagonists. Clin Ther. 1997; 19:3-17.
    • (1997) Clin Ther , vol.19 , pp. 3-17
    • Pitt, B.1
  • 9
    • 0022388247 scopus 로고
    • Calcium channel antagonists: Pharmacological considerations
    • Rampe D, Su CM, Yousif F et al. Calcium channel antagonists: pharmacological considerations. Br J Clin Pharmacol. 1985; 20(suppl 2):247S-254S.
    • (1985) Br J Clin Pharmacol , vol.20 , Issue.SUPPL. 2
    • Rampe, D.1    Su, C.M.2    Yousif, F.3
  • 10
    • 33244466298 scopus 로고    scopus 로고
    • Management of systemic and pulmonary hypertension
    • Levy JH. Management of systemic and pulmonary hypertension. Tex Heart Inst J. 2005; 32:467-71.
    • (2005) Tex Heart Inst J , vol.32 , pp. 467-471
    • Levy, J.H.1
  • 11
    • 0033003861 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of clevidipine in healthy volunteers after intravenous infusion
    • Ericsson H, Fakt C, Höglund L et al. Pharmacokinetics and pharmacodynamics of clevidipine in healthy volunteers after intravenous infusion. Eur J Clin Pharmacol. 1999; 55:61-7.
    • (1999) Eur J Clin Pharmacol , vol.55 , pp. 61-67
    • Ericsson, H.1    Fakt, C.2    Höglund, L.3
  • 12
    • 0032807949 scopus 로고    scopus 로고
    • Circulatory effects and pharmacology of clevidipine, a novel ultra short acting and vascular selective calcium antagonist, in hypertensive humans
    • Schwieler JH, Ericsson H, Lofdahn P et al. Circulatory effects and pharmacology of clevidipine, a novel ultra short acting and vascular selective calcium antagonist, in hypertensive humans. J Cardiovasc Pharmacol. 1999; 34:268-74.
    • (1999) J Cardiovasc Pharmacol , vol.34 , pp. 268-274
    • Schwieler, J.H.1    Ericsson, H.2    Lofdahn, P.3
  • 13
    • 0032922805 scopus 로고    scopus 로고
    • Clinical and pharmacokinetic results with a new ultrashort-acting calcium antagonist, clevidipine, following gradually increasing intravenous doses to healthy volunteers
    • Ericsson H, Fakt C, Jolin-Mellgård Å et al. Clinical and pharmacokinetic results with a new ultrashort-acting calcium antagonist, clevidipine, following gradually increasing intravenous doses to healthy volunteers. Br J Clin Pharmacol. 1999; 47:531-8.
    • (1999) Br J Clin Pharmacol , vol.47 , pp. 531-538
    • Ericsson, H.1    Fakt, C.2    Jolin-Mellgård, A.3
  • 14
    • 0027502514 scopus 로고
    • Comparative effects of felodipine, nitrendipine and nifedipine in healthy subjects: Concentration-effect relationships of racemic drugs and enantiomers
    • Soons PA, Cohen AF, Breimer DD. Comparative effects of felodipine, nitrendipine and nifedipine in healthy subjects: concentration-effect relationships of racemic drugs and enantiomers. Eur J Clin Pharmacol. 1993; 44:113-20.
    • (1993) Eur J Clin Pharmacol , vol.44 , pp. 113-120
    • Soons, P.A.1    Cohen, A.F.2    Breimer, D.D.3
  • 15
    • 18344372737 scopus 로고    scopus 로고
    • Clevidipine in adult cardiac surgical patients: A dose-finding study
    • Bailey JM, Lu W, Levy JH et al. Clevidipine in adult cardiac surgical patients: a dose-finding study. Anesthesiology. 2002; 96:1086-94.
    • (2002) Anesthesiology , vol.96 , pp. 1086-1094
    • Bailey, J.M.1    Lu, W.2    Levy, J.H.3
  • 16
    • 0034079587 scopus 로고    scopus 로고
    • Pharmacokinetics and arteriovenous differences in clevidipine concentration following short- and a long-term intravenous infusion in healthy volunteers
    • Ericsson H, Bredberg U, Eriksson U et al. Pharmacokinetics and arteriovenous differences in clevidipine concentration following short- and a long-term intravenous infusion in healthy volunteers. Anesthesiology. 2000; 92:993-1001.
    • (2000) Anesthesiology , vol.92 , pp. 993-1001
    • Ericsson, H.1    Bredberg, U.2    Eriksson, U.3
  • 17
    • 0033960750 scopus 로고    scopus 로고
    • Coronary and systemic hemodynamic effects of clevidipine, an ultra-short-acting calcium antagonist, for treatment of hypertension after coronary artery surgery
    • Kieler-Jensen N, Jolin-Mellgård Å, Nordlander M et al. Coronary and systemic hemodynamic effects of clevidipine, an ultra-short-acting calcium antagonist, for treatment of hypertension after coronary artery surgery. Acta Anaesth Scand. 2000; 44:186-93.
    • (2000) Acta Anaesth Scand , vol.44 , pp. 186-193
    • Kieler-Jensen, N.1    Jolin-Mellgård, A.2    Nordlander, M.3
  • 18
    • 0032979711 scopus 로고    scopus 로고
    • In vitro hydrolysis rate and protein binding of clevidipine, a new ultrashort-acting calcium antagonist metabolised by esterases, in different animal species and man
    • Ericsson H, Tholander B, Regårdh CG. In vitro hydrolysis rate and protein binding of clevidipine, a new ultrashort-acting calcium antagonist metabolised by esterases, in different animal species and man. Eur J Pharm Sci. 1999; 8:29-37.
    • (1999) Eur J Pharm Sci , vol.8 , pp. 29-37
    • Ericsson, H.1    Tholander, B.2    Regårdh, C.G.3
  • 19
    • 77949635176 scopus 로고    scopus 로고
    • Cleviprex (clevidipine butyrate injectable emulsion) product information. Clayton, NC: The Medicines Company; 2008.
    • Cleviprex (clevidipine butyrate injectable emulsion) product information. Clayton, NC: The Medicines Company; 2008.
  • 20
    • 0015318113 scopus 로고
    • General treatment of linear mammilary models with elimination from any compartment as used in pharmacokinetics
    • Benet LZ. General treatment of linear mammilary models with elimination from any compartment as used in pharmacokinetics. J Pharm Sci. 1972; 61:536-41.
    • (1972) J Pharm Sci , vol.61 , pp. 536-541
    • Benet, L.Z.1
  • 21
    • 0033760624 scopus 로고    scopus 로고
    • Pharmacokinetics and pulmonary extraction of clevidipine, a new vasodilating ultrashort-acting dihydropyridine, during cardiopulmonary bypass
    • Vuylsteke A, Milner Q, Ericsson H et al. Pharmacokinetics and pulmonary extraction of clevidipine, a new vasodilating ultrashort-acting dihydropyridine, during cardiopulmonary bypass. Br J Anaesth. 2000; 85:683-9.
    • (2000) Br J Anaesth , vol.85 , pp. 683-689
    • Vuylsteke, A.1    Milner, Q.2    Ericsson, H.3
  • 22
    • 60249101976 scopus 로고    scopus 로고
    • Clevidipine, an intravenous dihydropyridine calcium channel blocker, is safe and effective for the treatment of patients with acute severe hypertension
    • Pollack CV, Varon J, Garrison NA et al. Clevidipine, an intravenous dihydropyridine calcium channel blocker, is safe and effective for the treatment of patients with acute severe hypertension. Ann Emerg Med. 2009; 53:329-38.
    • (2009) Ann Emerg Med , vol.53 , pp. 329-338
    • Pollack, C.V.1    Varon, J.2    Garrison, N.A.3
  • 23
    • 53449096106 scopus 로고    scopus 로고
    • The ECLIPSE trials: Comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients
    • Aronson S, Dyke CM, Stierer KA et al. The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients. Anesth Analg. 2008; 107:1110-21.
    • (2008) Anesth Analg , vol.107 , pp. 1110-1121
    • Aronson, S.1    Dyke, C.M.2    Stierer, K.A.3
  • 24
    • 34748878874 scopus 로고    scopus 로고
    • Clevidipine effectively and rapidly controls blood pressure preoperatively in cardiac surgery patients: The results of the randomized, placebo-controlled efficacy study of clevidipine assessing its preoperative antihypertensive effect in cardiac surgery-1
    • Levy JH, Mancao MY, Gitter R et al. Clevidipine effectively and rapidly controls blood pressure preoperatively in cardiac surgery patients: the results of the randomized, placebo-controlled efficacy study of clevidipine assessing its preoperative antihypertensive effect in cardiac surgery-1. Anesth Analg. 2007; 105:918-25.
    • (2007) Anesth Analg , vol.105 , pp. 918-925
    • Levy, J.H.1    Mancao, M.Y.2    Gitter, R.3
  • 25
    • 33645836309 scopus 로고    scopus 로고
    • Human cytochrome p450 induction and inhibition potential of clevidipine and its primary metabolite h152/81
    • Zhang GJ, Dehal SS, Ho T et al. Human cytochrome p450 induction and inhibition potential of clevidipine and its primary metabolite h152/81. Drug Metab Dispos. 2006; 34:734-7.
    • (2006) Drug Metab Dispos , vol.34 , pp. 734-737
    • Zhang, G.J.1    Dehal, S.S.2    Ho, T.3
  • 26
    • 50449089263 scopus 로고    scopus 로고
    • Pharmacological interventions for hypertensive emergencies: A Cochrane systematic review
    • Perez MI, Musini VM. Pharmacological interventions for hypertensive emergencies: a Cochrane systematic review. J Hum Hypertens. 2008; 22:596-607.
    • (2008) J Hum Hypertens , vol.22 , pp. 596-607
    • Perez, M.I.1    Musini, V.M.2
  • 27
    • 0042364768 scopus 로고    scopus 로고
    • Comparison of clevidipine with sodium nitroprusside in the control of blood pressure after coronary artery surgery
    • Powroznyk AV, Vuylsteke A, Naughton C et al. Comparison of clevidipine with sodium nitroprusside in the control of blood pressure after coronary artery surgery. Eur J Anaesthesiol. 2003; 20:697-703.
    • (2003) Eur J Anaesthesiol , vol.20 , pp. 697-703
    • Powroznyk, A.V.1    Vuylsteke, A.2    Naughton, C.3
  • 28
    • 8344244425 scopus 로고    scopus 로고
    • Acute postoperative hypertension: A review of therapeutic options
    • Haas CE, LeBlanc JM. Acute postoperative hypertension: a review of therapeutic options. Am J Health-Syst Pharm. 2004; 61:1661-75.
    • (2004) Am J Health-Syst Pharm , vol.61 , pp. 1661-1675
    • Haas, C.E.1    LeBlanc, J.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.