Diarrhoeal disease through enterocyte secretion: A doctrine untroubled by proof

Experimental Physiology

Volumn 95, Issue 4, 2010, Pages 479-484

  Lucas, Michael L ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ENTEROTOXIN; TRANSMEMBRANE CONDUCTANCE REGULATOR;

CRYPT CELL; DIARRHEA; DISEASE ASSOCIATION; DISEASE COURSE; ESCHERICHIA COLI; IN VIVO STUDY; INTESTINE CELL; INTESTINE SECRETION; NONHUMAN; NOTE;

EID: 77949605970     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/expphysiol.2009.049437     Document Type: Note

References (31)

1. Dalldorf FG, Keusch GT Livingston HL (1969). Transcellular permeability of capillaries in experimental cholera. Am J Pathol 57, 153 169.
2. Eklund S, Jodal M Lundgren O (1985). The enteric nervous system participates in the secretory response to the heat stable enterotoxins of Escherichia coli in rats and cats. Neuroscience 14, 673 681.
3. Elliott HL, Carpenter CCJ, Sack RB Yardley JH (1970). Small bowel morphology in experimental canine cholera. Lab Invest 22, 112 120.
4. Fasano A, Uzzau S, Fiore C Margaretten K (1997). The enterotoxic effect of zona occludens toxin on rabbit small intestine involves the paracellular pathway. Gastroenterology 112, 839 846.
5. Field M (1971). Intestinal secretion: effect of cyclic AMP and its role in cholera. N Engl J Med 284, 1137 1143.
6. Field M, Graf LH Jr., Laird WJ Smith PL (1978). Heat-stable enterotoxin of Escherichia coli: in vitro effects on guanylate cyclase activity, cyclic GMP concentration, and ion transport in small intestine. Proc Natl Acad Sci USA 75, 2800 2804.
7. Flagella M, Clarke LL, Miller ML, Erway LC, Gianella RA, Andringa A, Gawenis LR, Kramer J, Duffy JJ, Doetschman T, Lorenz JN, Yamoah EN, Cardell EL Shull GE (1999). Mice lacking the basolateral Na-K-2Cl cotransporter have impaired epithelial chloride secretion and are profoundly deaf. J Biol Chem 274, 26946 26955.
8. Gianella RA (1976). Suckling mouse model for detection of heat-stable Escherichia coli enterotoxin: characteristics of the model. Infect Immun 14, 95 99.
9. - secretion is absent in cystic fibrosis. Gastroenterology 107, 950 956.
10. Gregory RA (1962). Secretory Mechanisms of the Gastrointestinal Tract. Physiological Society Monograph. Cambridge University Press, Cambridge, UK.
11. Huott PA, Liu W, McRoberts JA, Giannella RA Dharmsathaphorn K (1988). Mechanism of action of Escherichia coli heat stable enterotoxin in a human colonic cell line. J Clin Invest 82, 514 523.
12. Lucas ML (2005). Amendments to the theory underlying Ussing chamber data of chloride ion secretion after bacterial enterotoxin exposure. J Theor Biol 234, 21 37.
13. Lucas ML (2008a). Enterocyte chloride and water secretion into the small intestine: unifying hypothesis or intellectual dead end? J Physiol Biochem 64, 67 88.
14. Lucas ML (2008b). Translation of "Lieberkühn, J.N. De Fabrica et Actione villorum intestinorum tenuium Hominis". Lugduni Batavorum. Conrad et George Jac. Wishof, 1745. J Physiol Biochem 64, 387 414.
15. Lucas ML (2009). Shedding gloomy light into the black box of the Ussing chamber. Am J Physiol Gastrointest Liver Physiol 297, G858 G859.
16. Lucas ML, Duncan NW, O'Reilly NF, McIlvenny TJ Nelson YB (2008). Lack of evidence in vivo for a remote effect of Escherichia coli heat stable enterotoxin on jejunal fluid absorption. Neurogastroenterol Motil 20, 532 538.
17. Lucas ML, Thom MMM, Bradley JM, O'Reilly NF, McIlvenny TJ Nelson YB (2005). Escherichia coli heat stable (STa) enterotoxin and the upper small intestine: lack of evidence in vivo for net fluid secretion. J Membr Biol 206, 29 42.
18. Nelson YB, Pande D, McCormick J, Balloch KJD Lucas ML (2007). Lack of evidence in vivo for nitrergic inhibition by Escherichia coli (STa) enterotoxin of fluid absorption from rat proximal jejunum. J Physiol Biochem 63, 231 238.
19. Robert A, Nezamis JE, Lancaster C, Hanchar AJ Klepper MS (1976). Enteropooling assay - test for diarrhea produced by prostaglandins. Prostaglandins 11, 809 828.
20. Rolfe V Levin RJ (1994). Enterotoxin Escherichia coli STa activates a nitric oxide-dependent myenteric plexus secretory reflex in the rat ileum. J Physiol 475, 531 537.
21. Rolfe VE Levin RJ (1999). Vagotomy inhibits the jejunal fluid secretion activated by luminal ileal Escherichia coli STa in the rat in vivo. Gut 44, 615 619.
22. Schirgi-Degen A Beubler E (1998). Proabsorptive properties of nitric oxide. Digestion 59, 400 403
23. Sladen GE Harries JT (1972). Studies on the effects of unconjugated dihydroxy bile salts on rat small intestinal function in vivo. Biochim Biophys Acta 288, 443 456.
24. Solomon AK (1964). Validity of tracer measurements of fluxes in kidney tubules and other three compartment systems. In Transcellular Membrane Potentials and Ionic Fluxes, chap. IV, ed. Snell FM & Noell WK, pp. 47 63. Gordon & Breach, New York & London.
25. Sonawane ND, Hu J, Maunprasat C Verkman AS (2006). Luminally active, nonabsorbable CFTR inhibitors as potential therapy to reduce intestinal fluid loss in cholera. FASEB J 20, 130 132.
26. Tantisira MH, Jodal M Lundgren O (1990). Further studies of the changes in alkaline secretion, transepithelial potential difference and net fluid transport induced by the heat-stable enterotoxin of Escherichia coli (STa) in the rat jejunum in vivo. Acta Physiol Scand 140, 557 565.
27. Thiagarajah JR, Broadbent T, Hsieh E Verkman AS (2004). Prevention of toxin-induced intestinal ion and fluid secretion by a small-molecule CFTR inhibitor. Gastroenterology 126, 511 519.
28. Turvill JL, Kasapidis P Farthing MJG (1999). The sigma ligand, igmesine, inhibits cholera toxin and Escherichia coli enterotoxin induced jejunal secretion in the rat. Gut 45, 564 569.
29. Vaandrager AB, Bot AGM, Ruth P, Pfeifer A, Hofmann F De Jonge HR (2000). Differential role of cyclic GMP-dependent protein kinase II in ion transport in murine small intestine and colon. Gastroenterology 118, 108 114.
30. Wilson TH Wiseman G (1954). The use of sacs of everted small intestine for the study of the transference of substances from the mucosal to the serosal surface. J Physiol 123, 116 125.
31. 14C-polyethylene glycol 4000 in intestinal venous blood: influence of osmolarity and laxatives, effect on net water flux determination. Naunyn-Schmiedeberg's Archiv für Pharmakologie 321, 149 156.