Lack of evidence in vivo for a remote effect of Escherichia coli heat stable enterotoxin on jejunal fluid absorption

Neurogastroenterology and Motility

Volumn 20, Issue 5, 2008, Pages 532-538

  Lucas, M L ^a   Duncan, N W ^a   O'Reilly, N F ^a   McIlvenny, T J ^a   Nelson, Y B ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

E. coli STa; Enterotoxin; Fluid absorption; Intestine; Secretion; Vagotomy

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ESCHERICHIA COLI; FEMALE; HIGHLY SELECTIVE VAGOTOMY; ILEUM; IN VIVO STUDY; INTESTINE FLUID; INTESTINE SECRETION; JEJUNUM MUCOSA; NONHUMAN; PRIORITY JOURNAL; RAT; SMALL INTESTINE ABSORPTION; SPRAGUE DAWLEY RAT; THERMOSTABILITY; VAGUS NERVE; VAGUS NERVE STIMULATION;

ANIMALS; BACTERIAL TOXINS; ENTEROTOXINS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FEMALE; INTESTINAL ABSORPTION; INTESTINAL SECRETIONS; JEJUNUM; RATS; RATS, SPRAGUE-DAWLEY;

EID: 42249100518     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/j.1365-2982.2007.01046.x     Document Type: Article

References (19)

1. Eklund S., Jodal M, Lundgren O. The enteric nervous system participates in the secretory response to the heat stable enterotoxins of Escherichia coli in rats and cats. Neuroscience 1985 14:673 81.
2. Rolfe VE, Levin RJ. Vagotomy inhibits the jejunal fluid secretion activated by luminal ileal Escherichia coli STa in the rat in vivo. Gut 1999 44:615 9.
3. Staley TE, Jones EW, Smith-Staley JA. The effect of Escherichia coli enterotoxins on the small intestine with or without direct mucosal contact. Dig Dis 1973 18:751 6.
4. Hubel KA, Renquist KS, Varley G. Secretory reflexes in ileum and jejunum: absence of remote effects. J Auton Nerv Syst 1991 35:53 62.
5. Schanker LS, Tocco DJ, Brodie BB, Hogben CAM. Absorption of drugs from the rat small intestine. J Pharmacol Exp Ther 1958 123:81 8.
6. Lucas ML, Thom MMM, Bradley JM, O'Reilly NF, McIlvenny TJ, Nelson YB. Escherichia coli heat stable (STa) enterotoxin and the upper small intestine: lack of evidence in vivo for net fluid secretion. J Membrane Biol 2005 206:29 42.
7. Fedorak RN, Allen SL. Effect of somatostatin analog (SMS 201-995) on in vivo intestinal fluid transport in rats. A limited systemic effect. Dig Dis Sci 1989 34:567 72.
8. Sladen GE, Harries JT. Studies on the effects of unconjugated dihydroxy bile salts on rat small intestinal function in vivo. Biochim Biophys Acta 1972 288:443 56.
9. D'Amour FE, Blood FR, Belden DA Jr. Manual for Laboratory Work in Mammalian Physiology. Expn 10, 3rd edn. Chicago, USA:University of Chicago Press, 1974.
10. BMDP. Biomedical Programmes Manual. Los Angeles:UCLA Press, University of California, 1981.
11. Dunnett CW. New tables for multiple comparisons with a control. Biometrics 1964 20:482 91.
12. Jiang MM, Kirchgessner A, Gershon MD, Surprenant A. Cholera toxin-sensitive neurons in guinea-pig submucosal plexus. Am J Physiol 1993 264:G86 94.
13. Nocerino A, Iafusco M, Guandalini S. Cholera toxin- induced small intestinal secretion has a secretory effect on the colon of the rat. Gastroenterology 1995 108:34 9.
14. Tidball CS, Tidball ME. Changes in intestinal net absorption of a sodium chloride solution produced by atropine in normal and vagotomized dogs. Am J Physiol 1958 193:25 8.
15. Bunch GA, Shields RA. Effect of vagotomy on the intestinal handling of water and electrolytes. Gut 1973 14:116 9.
16. Sjövall H, Brunsson I, Jodal M, Lundgren O. The effect of vagal nerve stimulation on net fluid transport in the small intestine of the cat. Acta Physiol Scand 1983 117:351 7.
17. Chu X, Zhang X, Renehan WE, Beierwaltes WH, Fogel R. Intestinal distension alters vagal efferent activity and small intestinal transport in vivo. Am J Physiol 1993 264:G341 50.
18. Sjövall H, Butcher P, Martner J, Sellden H. Cardiac receptor modulation of blood flow and fluid transport in feline jejunum. Am J Physiol 1987 253:G116 23.
19. Wright AM, Gong X, Verdon B et al. Novel regulation of cystic fibrosis transmembrane conductance regulator (CFTR) channel gating by external chloride. J Biol Chem 2004 279:41658 63.