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Volumn 11, Issue 1, 2010, Pages

Genetic selection? A study of individual variation in the enzymes of folate metabolism

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); DNA; FOLIC ACID; THYMIDYLATE SYNTHASE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2);

EID: 77949562815     PISSN: None     EISSN: 14712350     Source Type: Journal    
DOI: 10.1186/1471-2350-11-18     Document Type: Article
Times cited : (7)

References (27)
  • 1
    • 0037164375 scopus 로고    scopus 로고
    • Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis
    • 10.1136/bmj.325.7374.1202, 135491, 12446535
    • Wald DS, Law M, Morris JK. Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis. Bmj 2002, 325(7374):1202. 10.1136/bmj.325.7374.1202, 135491, 12446535.
    • (2002) Bmj , vol.325 , Issue.7374 , pp. 1202
    • Wald, D.S.1    Law, M.2    Morris, J.K.3
  • 2
    • 3042784787 scopus 로고    scopus 로고
    • Impact of the MTHFR C677T polymorphism on risk of neural tube defects: case-control study
    • 10.1136/bmj.38036.646030.EE, 437144, 15155469
    • Kirke PN, Mills JL, Molloy AM, Brody LC, O'Leary VB, Daly L, Murray S, Conley M, Mayne PD, Smith O, et al. Impact of the MTHFR C677T polymorphism on risk of neural tube defects: case-control study. Bmj 2004, 328(7455):1535-1536. 10.1136/bmj.38036.646030.EE, 437144, 15155469.
    • (2004) Bmj , vol.328 , Issue.7455 , pp. 1535-1536
    • Kirke, P.N.1    Mills, J.L.2    Molloy, A.M.3    Brody, L.C.4    O'Leary, V.B.5    Daly, L.6    Murray, S.7    Conley, M.8    Mayne, P.D.9    Smith, O.10
  • 3
    • 0033365197 scopus 로고    scopus 로고
    • The "thermolabile" variant of methylenetetrahydrofolate reductase and neural tube defects: An evaluation of genetic risk and the relative importance of the genotypes of the embryo and the mother
    • 10.1086/302310, 1377828, 10090889
    • Shields DC, Kirke PN, Mills JL, Ramsbottom D, Molloy AM, Burke H, Weir DG, Scott JM, Whitehead AS. The "thermolabile" variant of methylenetetrahydrofolate reductase and neural tube defects: An evaluation of genetic risk and the relative importance of the genotypes of the embryo and the mother. Am J Hum Genet 1999, 64(4):1045-1055. 10.1086/302310, 1377828, 10090889.
    • (1999) Am J Hum Genet , vol.64 , Issue.4 , pp. 1045-1055
    • Shields, D.C.1    Kirke, P.N.2    Mills, J.L.3    Ramsbottom, D.4    Molloy, A.M.5    Burke, H.6    Weir, D.G.7    Scott, J.M.8    Whitehead, A.S.9
  • 4
    • 0033846999 scopus 로고    scopus 로고
    • Polymorphisms in genes involved in folate metabolism as maternal risk factors for Down syndrome
    • 10.1086/303055, 1287522, 10930360
    • Hobbs CA, Sherman SL, Yi P, Hopkins SE, Torfs CP, Hine RJ, Pogribna M, Rozen R, James SJ. Polymorphisms in genes involved in folate metabolism as maternal risk factors for Down syndrome. Am J Hum Genet 2000, 67(3):623-630. 10.1086/303055, 1287522, 10930360.
    • (2000) Am J Hum Genet , vol.67 , Issue.3 , pp. 623-630
    • Hobbs, C.A.1    Sherman, S.L.2    Yi, P.3    Hopkins, S.E.4    Torfs, C.P.5    Hine, R.J.6    Pogribna, M.7    Rozen, R.8    James, S.J.9
  • 5
    • 0742304414 scopus 로고    scopus 로고
    • Is folic acid the ultimate functional food component for disease prevention?
    • 10.1136/bmj.328.7433.211, 318492, 14739191
    • Lucock M. Is folic acid the ultimate functional food component for disease prevention?. Bmj 2004, 328(7433):211-214. 10.1136/bmj.328.7433.211, 318492, 14739191.
    • (2004) Bmj , vol.328 , Issue.7433 , pp. 211-214
    • Lucock, M.1
  • 6
    • 0003884027 scopus 로고    scopus 로고
    • Report on health social subjects. 50. Folic acid and the prevention of disease. Report of the Committee on Medical Aspects of Food and Nutrition Policy
    • London: The Stationary Office, Department of Health
    • Department of Health Report on health social subjects. 50. Folic acid and the prevention of disease. Report of the Committee on Medical Aspects of Food and Nutrition Policy. 2000, London: The Stationary Office, Department of Health.
    • (2000)
  • 7
    • 1942469552 scopus 로고    scopus 로고
    • Gene-gene interaction in folate-related genes and risk of neural tube defects in a UK population
    • 10.1136/jmg.2003.010694, 1735724, 15060097
    • Relton CL, Wilding CS, Pearce MS, Laffling AJ, Jonas PA, Lynch SA, Tawn EJ, Burn J. Gene-gene interaction in folate-related genes and risk of neural tube defects in a UK population. J Med Genet 2004, 41(4):256-260. 10.1136/jmg.2003.010694, 1735724, 15060097.
    • (2004) J Med Genet , vol.41 , Issue.4 , pp. 256-260
    • Relton, C.L.1    Wilding, C.S.2    Pearce, M.S.3    Laffling, A.J.4    Jonas, P.A.5    Lynch, S.A.6    Tawn, E.J.7    Burn, J.8
  • 8
    • 33646166386 scopus 로고    scopus 로고
    • Effect of B vitamins and genetics on success of in-vitro fertilisation: prospective cohort study
    • 10.1016/S0140-6736(06)68651-0, 16679164
    • Haggarty P, McCallum H, McBain H, Andrews K, Duthie S, McNeill G, Templeton A, Haites N, Campbell D, Bhattacharya S. Effect of B vitamins and genetics on success of in-vitro fertilisation: prospective cohort study. Lancet 2006, 367(9521):1513-1519. 10.1016/S0140-6736(06)68651-0, 16679164.
    • (2006) Lancet , vol.367 , Issue.9521 , pp. 1513-1519
    • Haggarty, P.1    McCallum, H.2    McBain, H.3    Andrews, K.4    Duthie, S.5    McNeill, G.6    Templeton, A.7    Haites, N.8    Campbell, D.9    Bhattacharya, S.10
  • 10
    • 0033638057 scopus 로고    scopus 로고
    • Hyperhomocysteinemia and recurrent early pregnancy loss: a meta-analysis
    • 10.1016/S0015-0282(00)01595-8, 11119750
    • Nelen WL, Blom HJ, Steegers EA, den Heijer M, Eskes TK. Hyperhomocysteinemia and recurrent early pregnancy loss: a meta-analysis. Fertil Steril 2000, 74(6):1196-1199. 10.1016/S0015-0282(00)01595-8, 11119750.
    • (2000) Fertil Steril , vol.74 , Issue.6 , pp. 1196-1199
    • Nelen, W.L.1    Blom, H.J.2    Steegers, E.A.3    den Heijer, M.4    Eskes, T.K.5
  • 11
    • 34247844422 scopus 로고    scopus 로고
    • Hyperhomocysteinemia and MTHFR polymorphisms in association with orofacial clefts and congenital heart defects: a meta-analysis
    • 10.1002/ajmg.a.31684, 17431894, A
    • Verkleij-Hagoort A, Bliek J, Sayed-Tabatabaei F, Ursem N, Steegers E, Steegers-Theunissen R. Hyperhomocysteinemia and MTHFR polymorphisms in association with orofacial clefts and congenital heart defects: a meta-analysis. Am J Med Genet A 2007, 143A(9):952-960. 10.1002/ajmg.a.31684, 17431894.
    • (2007) Am J Med Genet A , vol.143 , Issue.9 , pp. 952-960
    • Verkleij-Hagoort, A.1    Bliek, J.2    Sayed-Tabatabaei, F.3    Ursem, N.4    Steegers, E.5    Steegers-Theunissen, R.6
  • 12
    • 14344254781 scopus 로고    scopus 로고
    • Folic acid - vitamin and panacea or genetic time bomb?
    • 10.1038/nrg1558, 15738964
    • Lucock M, Yates Z. Folic acid - vitamin and panacea or genetic time bomb?. Nat Rev Genet 2005, 6(3):235-240. 10.1038/nrg1558, 15738964.
    • (2005) Nat Rev Genet , vol.6 , Issue.3 , pp. 235-240
    • Lucock, M.1    Yates, Z.2
  • 14
    • 0032906750 scopus 로고    scopus 로고
    • Polymorphisms of methylenetetrahydrofolate reductase and other enzymes: metabolic significance, risks and impact on folate requirement
    • Bailey LB, Gregory JF. Polymorphisms of methylenetetrahydrofolate reductase and other enzymes: metabolic significance, risks and impact on folate requirement. J Nutr 1999, 129(5):919-922.
    • (1999) J Nutr , vol.129 , Issue.5 , pp. 919-922
    • Bailey, L.B.1    Gregory, J.F.2
  • 15
    • 0034190659 scopus 로고    scopus 로고
    • 5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review
    • Botto LD, Yang Q. 5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review. Am J Epidemiol 2000, 151(9):862-877.
    • (2000) Am J Epidemiol , vol.151 , Issue.9 , pp. 862-877
    • Botto, L.D.1    Yang, Q.2
  • 16
    • 3242886458 scopus 로고    scopus 로고
    • Thymidylate synthase repeat polymorphisms and risk of neural tube defects in a population from the northern United Kingdom
    • 10.1002/bdra.20038, 15259039
    • Wilding CS, Relton CL, Sutton MJ, Jonas PA, Lynch SA, Tawn EJ, Burn J. Thymidylate synthase repeat polymorphisms and risk of neural tube defects in a population from the northern United Kingdom. Birth Defects Res A Clin Mol Teratol 2004, 70(7):483-485. 10.1002/bdra.20038, 15259039.
    • (2004) Birth Defects Res A Clin Mol Teratol , vol.70 , Issue.7 , pp. 483-485
    • Wilding, C.S.1    Relton, C.L.2    Sutton, M.J.3    Jonas, P.A.4    Lynch, S.A.5    Tawn, E.J.6    Burn, J.7
  • 17
    • 0036765747 scopus 로고    scopus 로고
    • Thymidylate synthase: a novel genetic determinant of plasma homocysteine and folate levels
    • 10.1007/s00439-002-0779-2, 12215845
    • Trinh BN, Ong CN, Coetzee GA, Yu MC, Laird PW. Thymidylate synthase: a novel genetic determinant of plasma homocysteine and folate levels. Hum Genet 2002, 111(3):299-302. 10.1007/s00439-002-0779-2, 12215845.
    • (2002) Hum Genet , vol.111 , Issue.3 , pp. 299-302
    • Trinh, B.N.1    Ong, C.N.2    Coetzee, G.A.3    Yu, M.C.4    Laird, P.W.5
  • 18
    • 0032987508 scopus 로고    scopus 로고
    • Mortality risk in men is associated with a common mutation in the methylene-tetrahydrofolate reductase gene (MTHFR)
    • 10.1038/sj.ejhg.5200283, 10196703
    • Heijmans BT, Gussekloo J, Kluft C, Droog S, Lagaay AM, Knook DL, Westendorp RG, Slagboom EP. Mortality risk in men is associated with a common mutation in the methylene-tetrahydrofolate reductase gene (MTHFR). Eur J Hum Genet 1999, 7(2):197-204. 10.1038/sj.ejhg.5200283, 10196703.
    • (1999) Eur J Hum Genet , vol.7 , Issue.2 , pp. 197-204
    • Heijmans, B.T.1    Gussekloo, J.2    Kluft, C.3    Droog, S.4    Lagaay, A.M.5    Knook, D.L.6    Westendorp, R.G.7    Slagboom, E.P.8
  • 22
    • 61549129618 scopus 로고    scopus 로고
    • Peripheral arterial disease and methylenetetrahydrofolate reductase (MTHFR) C677T mutations: A case-control study and meta-analysis
    • 10.1016/j.jvs.2008.10.004, 19157768
    • Khandanpour N, Willis G, Meyer FJ, Armon MP, Loke YK, Wright AJ, Finglas PM, Jennings BA. Peripheral arterial disease and methylenetetrahydrofolate reductase (MTHFR) C677T mutations: A case-control study and meta-analysis. J Vasc Surg 2009, 49(3):711-718. 10.1016/j.jvs.2008.10.004, 19157768.
    • (2009) J Vasc Surg , vol.49 , Issue.3 , pp. 711-718
    • Khandanpour, N.1    Willis, G.2    Meyer, F.J.3    Armon, M.P.4    Loke, Y.K.5    Wright, A.J.6    Finglas, P.M.7    Jennings, B.A.8
  • 23
    • 0031945194 scopus 로고    scopus 로고
    • The North Cumbria Community Genetics Project
    • 10.1136/jmg.35.5.413, 1051317, 9610806
    • Chase DS, Tawn EJ, Parker L, Jonas P, Parker CO, Burn J. The North Cumbria Community Genetics Project. J Med Genet 1998, 35(5):413-416. 10.1136/jmg.35.5.413, 1051317, 9610806.
    • (1998) J Med Genet , vol.35 , Issue.5 , pp. 413-416
    • Chase, D.S.1    Tawn, E.J.2    Parker, L.3    Jonas, P.4    Parker, C.O.5    Burn, J.6
  • 24
    • 0025008320 scopus 로고
    • A Consensus Combined P-Value Test and the Family-Wide Significance of Component Tests
    • Rice WR. A Consensus Combined P-Value Test and the Family-Wide Significance of Component Tests. Biometrics 1990, 46(2):303-308.
    • (1990) Biometrics , vol.46 , Issue.2 , pp. 303-308
    • Rice, W.R.1
  • 25
    • 17444448466 scopus 로고    scopus 로고
    • Evidence for extensive transmission distortion in the human genome
    • 10.1086/381131, 1181913, 14681832
    • Zollner S, Wen X, Hanchard NA, Herbert MA, Ober C, Pritchard JK. Evidence for extensive transmission distortion in the human genome. Am J Hum Genet 2004, 74(1):62-72. 10.1086/381131, 1181913, 14681832.
    • (2004) Am J Hum Genet , vol.74 , Issue.1 , pp. 62-72
    • Zollner, S.1    Wen, X.2    Hanchard, N.A.3    Herbert, M.A.4    Ober, C.5    Pritchard, J.K.6
  • 26
    • 0242661475 scopus 로고    scopus 로고
    • C677T methylenetetrahydrofolate reductase polymorphism interferes with the effects of folic acid and zinc sulfate on sperm concentration
    • 10.1016/S0015-0282(03)02157-5, 14607573
    • Ebisch IM, van Heerde WL, Thomas CM, Put N, Wong WY, Steegers-Theunissen RP. C677T methylenetetrahydrofolate reductase polymorphism interferes with the effects of folic acid and zinc sulfate on sperm concentration. Fertil Steril 2003, 80(5):1190-1194. 10.1016/S0015-0282(03)02157-5, 14607573.
    • (2003) Fertil Steril , vol.80 , Issue.5 , pp. 1190-1194
    • Ebisch, I.M.1    van Heerde, W.L.2    Thomas, C.M.3    Put, N.4    Wong, W.Y.5    Steegers-Theunissen, R.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.