Human papillomavirus genotyping in histological sections of precursor lesions of cervical carcinoma: Its role as a possible adjunct for the evaluation of the oncogenic potential of specific human papillomavirus genotypes - A study in a Coastal Region of Southeastern Spain

Gynecologic and Obstetric Investigation

Volumn 70, Issue 2, 2010, Pages 113-119

  Doménech Peris, Asunción ^a   Conesa Zamora, Pablo ^a   Sahuquillo Frias, Laura ^a   Ortiz Reina, Sebastián ^a   Moya Biosca, Joaquín ^a   Acosta Ortega, Jesús ^a   Pérez Guillermo, Miguel ^a   Egea Cortines, Marcos ^b  

^a Hospital Universitario Santa Maria Del Rosell   (Spain)

^b TECHNICAL UNIVERSITY OF CARTAGENA   (Spain)

Author keywords

Genotype distribution; Human papillomavirus; Metaplasia, atypical immature; Paraffin embedded specimens; Squamous intraepithelial lesion

Indexed keywords

PARAFFIN; WART VIRUS VACCINE;

ADULT; AGED; ARTICLE; CANCER GRADING; CANCER INVASION; CANCER RISK; CARCINOGENESIS; CLINICAL EVALUATION; CONTROLLED STUDY; DRUG EFFICACY; ENDOMETRIUM CYTOLOGY; FEMALE; GENOTYPE; HISTOPATHOLOGY; HUMAN; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN PAPILLOMAVIRUS TYPE 18; HUMAN PAPILLOMAVIRUS TYPE 58; MAJOR CLINICAL STUDY; METAPLASIA; PREVALENCE; PRIORITY JOURNAL; SPAIN; UTERINE CERVIX CARCINOMA; VACCINATION; VIRUS DETECTION; VIRUS INFECTION; WART VIRUS;

ADULT; AGED; CARCINOMA, SQUAMOUS CELL; FEMALE; GENETIC VARIATION; GENOTYPE; HUMAN PAPILLOMAVIRUS 16; HUMAN PAPILLOMAVIRUS 18; HUMANS; MIDDLE AGED; PAPILLOMAVIRUS INFECTIONS; PAPILLOMAVIRUS VACCINES; PREVALENCE; RISK FACTORS; SPAIN; UTERINE CERVICAL NEOPLASMS; YOUNG ADULT;

EID: 77949558002     PISSN: 03787346     EISSN: None     Source Type: Journal    
DOI: 10.1159/000299819     Document Type: Article

References (31)

1. zur Hausen H: Oncogenic DNA viruses. Oncogene 2001; 20: 7820-7823.
2. Crum CP, Egawa K, Fu YS, Lancaster WD, Barron B, Levine RU, Fenoglio CM, Richart RM: Atypical immature metaplasia (AIM). A subset of human papilloma virus infection of the cervix. Cancer 1983; 51: 2214-2219.
3. Regauer S, Reich O: CK17 and p16 expression patterns distinguish (atypical) immature squamous metaplasia from high-grade cervical intraepithelial neoplasia (CIN III). Histopathology 2007; 50: 629-635.
4. de Villiers EM, Fauquet C, Broker TR, Bernard HU, zur Hausen H: Classification of papillomaviruses. Virology 2004; 324: 17-27.
5. Bernard HU: The clinical importance of the nomenclature, evolution and taxonomy of human papillomaviruses. J Clin Virol 2005; 32:S1-S6.
6. zur Hausen H: Papillomaviruses and cancer: From basic studies to clinical application. Nat Rev Cancer 2002; 2: 342-350.
7. Muñoz N, Bosch FX, de Sanjosé S, Herrero R, Castellsagué X, Shah KV, Snijders PJ, Meijer CJ; International Agency for Research on Cancer Multicenter Cervical Cancer Study Group: Epidemiologic classification of human papillomavirus types associated with cervical cancer. N Engl J Med 2003; 348: 518-527.
8. Muñoz N, Bosch FX, Catellsague X, Díaz M, de Sanjose S, Hammouda D, Shah KV, Meijer CJ: Against which human papillomavirus types should we vaccinate and screen? The international perspective. Int J Cancer 2004; 111: 278-285.
9. Eiben GL, Da Silva DM, Fausch SC, Le Poole IC, Nishimura MI, Kast WM: Cervical cancer vaccines: recent advances in HPV research. Viral Immunol 2003; 16: 111-121.
10. Paavonen J, Jenkins D, Bosch FX, Naud P, Salmerón J, Wheeler CM, Chow SN, Alter DL, Kitchener HC, Castellsague X, de Carvalho NS, Skinner SR, Harper DM, Hedrick JA, Jaisamrarn U, Limson GA, Dionne M, Quint W, Spiessens B, Peeters P, Struyf F, Wieting SL, Lehtinen MO, Dubin G; HPV PATRICIA study group: Efficacy of a prophylactic adjuvanted bivalent L1 viruslike- particle vaccine against infection with human papillomavirus types 16 and 18 in young women: an interim analysis of a phase III double-blind, randomised controlled trial. Lancet 2007; 369: 2161-2170.
11. Villa LL, Costa RLR, Petta CA, Andrade RP, Paavonen J, Iversen OE, Olsson SE, Høye J, Steinwall M, Riis-Johannessen G, Andersson- Ellstrom A, Elfgren K, Krogh G, Lehtinen M, Malm C, Tamms GM, Giacoletti K, Lupinacci L, Railkar R, Taddeo FJ, Bryan J, Esser MT, Sings HL, Saah AJ, Barr E: High sustained efficacy of a prophylactic quadrivalent human papillomavirus types 6/11/16/18 L1 virus-like particle vaccine through 5 years of follow-up. Br J Cancer 2006; 95: 1459-1466.
12. Woodman CBJ, Collins SI, Young LS: The natural history of cervical HPV infection: unresolved issues. Nat Rev Cancer 2007; 7: 11-22.
13. Grisaru D, Avidor B, Niv J, Marmor S, Almog B, Leibowitz C, Graidy M, Giladi M: Pilot study of prevalence of high-risk human papillomavirus genotypes in Israeli Jewish women referred for colposcopic examination. J Clin Microbiol 2008; 46: 1602-1605.
14. Alameda F, Bellosillo B, Fusté P, Musset M, Mariñoso ML, Mancebo G, Lopez-Yarto MT, Carreras R, Serrano S: Human papillomavirus detection in urine samples: an alternative screening method. J Low Genit Tract Dis 2007; 11: 5-7.
15. Conesa-Zamora P, Domenech-Peris A, Ortiz- Reina S, Orantes-Casado FJ, Acosta- Ortega J, García-Solano J, Pérez-Guillermo M: Immunohistochemical evaluation of ProEx C in human papillomavirus-induced lesions of the cervix. J Clin Pathol 2009; 62: 159-162.
16. Calleja-Macías IE, Villa LL, Prado JC, Kalantari M, Allan B, Williamson AL, Cheng LP, Collins RJ, Zuna RE, Dunn ST, Chu TY, Cubie HA, Cuschieri K, von Knebel-Doeberitz M, Martins CR, Sanchez GI, Bosch FX, Munoz N, Bernard HU: Worldwide genomic diversity of the high-risk human papillomavirus types 31, 35, 52, and 58, four close relatives of human papillomavirus type 16. J Virol 2005; 79: 13630-13640.
17. Prado JC, Calleja-Macías IE, Bernard HU, Kalantari M, Macay SA, Allan B, Williamson AL, Chung LP, Collins RJ, Zuna RE, Dunn ST, Ortiz-Lopez R, Barrera-Saldaña HA, Cubie HA, Cuschieri K, von Knebel-Doeberitz M, Sanchez GI, Bosch FX, Villa LL: Worldwide genomic diversity of the human papillomaviruses- 53, 56, and 66, a group of highrisk HPVs unrelated to HPV-16 and HPV-18. Virology 2005; 340: 95-104.
18. Calleja-Macías IE, Kalantari M, Huh J, Ortiz- Lopez R, Rojas-Martinez A, Gonzalez- Guerrero JF, Williamson AL, Hagmar B, Wiley DJ, Villarreal L, Bernard HU, Barrera- Saldaña HA: Genomic diversity of human papillomavirus-16, 18, 31, and 35 isolates in a Mexican population and relationship to European, African, and Native American variants. Virology 2004; 319: 315-323.
19. Clifford GM, Rana RK, Franceschi S, Smith JS, Gough G, Pimenta JM: Human papillomavirus genotype distribution in low-grade cervical lesions: comparison by geographic region and with cervical cancer. Cancer Epidemiol Biomarkers Prev 2005; 14: 1157-1164.
20. Xi LF, Koutsky LA, Hildesheim A, Galloway DA, Wheeler CM, Winer RL, Ho J, Kiviat NB: Risk for high-grade cervical intraepithelial neoplasia associated with variants of human papillomavirus types 16 and 18. Cancer Epidemiol Biomarkers Prev 2007; 16: 4-10.
21. Qiu AD, Wu EQ, Yu XH, Jiang CL, Jin YH, Wu YG, Chen Y, Chen Y, Shan YM, Zhang GN, Fan Y, Zha X, Kong W: HPV prevalence, E6 sequence variation and physical state of HPV16 isolates from patients with cervical cancer in Sichuan, China. Gynecol Oncol 2007; 104: 77-85.
22. Ortiz M, Torres M, Muñoz L, Fernández- García E, Canals J, Cabornero AI, Aguilar E, Ballesteros J, Del Amo J, García-Sáiz A: Oncogenic human papillomavirus (HPV) type distribution and HPV type 16 E6 variants in two Spanish population groups with different levels of HPV infection risk. Clin Microbiol 2006; 44: 1428-1434.
23. De Marco F, Houissa-Kchouk F, Khelifa R, Marcante ML: High-risk HPV types in Tunisia. A pilot study reveals an unexpectedly high prevalence of types 58 and 82 and lack of HPV 18 among female prostitutes. J Med Virol 2006; 78: 950-953.
24. Clifford GM, Gallus S, Herrero R, Muñoz N, Snijders PJ, Vaccarella S, Anh PT, Ferreccio C, Hieu NT, Matos E, Molano M, Rajkumar R, Ronco G, de Sanjosé S, Shin HR, Sukvirach S, Thomas JO, Tunsakul S, Meijer CJ, Franceschi S: Worldwide distribution of human papillomavirus types in cytologically normal women in the International Agency for Research on Cancer HPV prevalence surveys: a pooled analysis. Lancet 2005; 366: 991-998.
25. DeMay RM: The Pap smear; in DeMay RM (ed): The Art and Science of Cytophology. Chicago, American Society of Clinical Pathology Press, 1996, pp 61-205.
26. Rousseau MC, Villa LL, Costa MC, Abrahamowicz M, Rohan TE, Franco E: Occurrence of cervical infection with multiple human papillomavirus types is associated with age and cytologic abnormalities. Sex Transm Dis 2003; 30: 581-587.
27. Duggan MA, Akbari M, Magliocco AM: Atypical immature cervical metaplasia: immunoprofiling and longitudinal outcome. Hum Pathol 2006; 37: 1473-1481.
28. Iaconis L, Hyjek E, Ellenson LH, Pirog EC: p16 and Ki-67 immunostaining in atypical immature squamous metaplasia of the uterine cervix: correlation with human papillomavirus detection. Arch Pathol Lab Med 2007; 131: 1343-1349.
29. Geng L, Connolly DC, Isacson C, Ronnett BM, Cho KR: Atypical immature metaplasia (AIM) of the cervix: is it related to highgrade squamous intraepithelial lesion (HSIL)?. Hum Pathol 1999; 30: 345-351.
30. Miyatake T, Ueda Y, Yoshino K, Shroyer KR, Kanao H, Sun H, Nakashima R, Kimura T, Wakasa T, Enomoto T: Clonality analysis and human papillomavirus infection in squamous metaplasia and atypical immature metaplasia of uterine cervix: is atypical immature metaplasia a precursor to cervical intraepithelial neoplasia 3?. Int J Gynecol Pathol 2007; 26: 180-187.
31. Conesa-Zamora P, Doménech-Peris A, Orantes-Casado FJ, Ortiz-Reina S, Orantes- Casado FJ, Acosta-Ortega J, García-Solano J, Pérez-Guillermo M: Effect of Human Papillomavirus on cell cycle related proteins p16, Ki67, cyclin D1, p53 and ProEx C in precursor lesions of cervical carcinoma. A tissue microarray study. Am J Clin Pathol 2009; 132: 378-390.