Oral cleansing with chlorhexidine to decrease the incidence of nosocomial pneumonia: Using the right concentration in the right place

Infection Control and Hospital Epidemiology

Volumn 31, Issue 4, 2010, Pages 429-

  Panchabhai, Tanmay S ^a   Dangayach, Neha S ^b  

^a University of Louisville School of Medicine   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORHEXIDINE; PLACEBO;

ARTIFICIAL VENTILATION; HOSPITAL INFECTION; HUMAN; INTENSIVE CARE UNIT; LETTER; MORBIDITY; MORTALITY; MOUTH HYGIENE; PNEUMONIA; PROGNOSIS;

ADMINISTRATION, ORAL; ANTI-INFECTIVE AGENTS, LOCAL; CHLORHEXIDINE; CROSS INFECTION; HUMANS; INCIDENCE; INTENSIVE CARE UNITS; OROPHARYNX; PNEUMONIA, BACTERIAL; TREATMENT OUTCOME;

EID: 77949548891     PISSN: 0899823X     EISSN: None     Source Type: Journal    
DOI: 10.1086/651307     Document Type: Letter

References (8)

1. Bellissimo-Rodrigues F, Bellissimo-Rodrigues WT, Viana JM, et al. Effectiveness of oral rinse with chlorhexidine in preventing nosocomial respiratory tract infections amongst intensive care unit patients. Infect Control Hosp Epidemiol 2009; 30:952-958.
2. Ascenzi JM, Favero MS. Disinfectants and antiseptics, modes of action, mechanisms of resistance, and testing. In: Lorian V, ed. Antibiotics in laboratory medicine. 5th ed. Philadelphia: Lippincott Williams and Wilkins, 2005:615-653.
3. Panchabhai TS, Dangayach NS, Krishnan A, Kothari VM, Karnad DR. Oropharyngeal cleansing with 0.2‰ chlorhexidine for prevention of nosocomial pneumonia in critically ill patients: an open label randomized trial with 0.01‰ potassium permanganate as control. Chest 2009; 135: 1150-1156.
4. Fourrier F, Cau-Pottier E, Boutigny H, et al. Effects of dental plaque antiseptic decontamination on bacterial colonization and nosocomial infections in critically ill patients. Intensive Care Med 2000; 26:1239-1247.
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6. MacNaughton P, Bailey J, Donlin N, et al. A randomized controlled trial assessing efficacy of oral chlorhexidine in ventilated patients. European Society of Intensive Care Medicine, 17th Annual Congress, Berlin, Germany. Intensive Care Med 2004; 30(Suppl 1):S5-S18.
7. Koeman M, van der Ven AJ, Hak E, et al. Oral decontamination with chlorhexidine reduces incidence of ventilator-associated pneumonia. Am J Respir Crit Care Med 2006; 173:1348-1355.
8. Tantipong H, Morkchareonpong C, Jaiyindee S, et al. Randomized controlled trial and meta-analysis of oral decontamination with 2‰ chlorhexidine solution for the prevention of ventilator-associated pneumonia. Infect Control Hosp Epidemiol 2008; 29:131-136.