Screening for heart disease: C-reactive protein versus coronary artery calcium

Expert Review of Cardiovascular Therapy

Volumn 8, Issue 1, 2010, Pages 125-131

  Patel, Amish A ^a   Budoff, Matthew J ^a  

^a LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE   (United States)

Author keywords

atherosclerosis; C reactive protein; coronary artery calcium; coronary heart disease; risk factor

Indexed keywords

C REACTIVE PROTEIN; FIBRINOGEN; INTERLEUKIN 6; BIOLOGICAL MARKER; CALCIUM;

ALGORITHM; ANGINA PECTORIS; ARTERY CALCIFICATION; CARDIOVASCULAR RISK; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CORONARY ARTERY; DISEASE MARKER; ELECTROCARDIOGRAPHY; ELECTRON BEAM TOMOGRAPHY; HEART ARREST; HEART INFARCTION; HUMAN; INFLAMMATION; ISCHEMIC HEART DISEASE; MULTIDETECTOR COMPUTED TOMOGRAPHY; PATIENT CODING; PREDICTION; PROTEIN BLOOD LEVEL; RADIATION DOSE; RADIATION EXPOSURE; REVIEW; RISK ASSESSMENT; SCREENING TEST; STROKE; CALCINOSIS; CORONARY ARTERY DISEASE; COST; ECONOMICS; MASS SCREENING; METABOLISM; METHODOLOGY; RISK FACTOR;

ALGORITHMS; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CALCINOSIS; CALCIUM; CORONARY DISEASE; COSTS AND COST ANALYSIS; HUMANS; MASS SCREENING; RISK FACTORS;

EID: 77949536924     PISSN: 14779072     EISSN: 17448344     Source Type: Journal    
DOI: 10.1586/erc.09.166     Document Type: Review

References (52)

1. Lloyd-Jones D, Adams R, Carnethon M et al. Heart disease and stroke statistics - 2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 119(3), e21-e181 (2009).
2. Dawber TR, Kannel WB, Revotskie N, Stokes JI, Kagan A, Gordon T. Some factors associated with the development of coronary heart disease. Six years' follow-up experience in the Framingham Study. Am. J. Public Health 49(10), 1349-1356 (1959).
3. Wilson PW, D'Agostino RB, Levy D, Belanger AM, Silbershatz H, Kannel WB. Prediction of coronary heart disease using risk factor categories. Circulation 97(18), 1837-1847 (1998).
4. Llloyd-Jones DM, Larson MG, Beiser A, Levy D. Lifetime risk of developing coronary heart disease. Lancet 353(9147), 89-92 (1999).
5. Goraya TY, Jacobsen SJ, Kottke TE, Frye RL, Weston SA, Roger VI. Coronary heart disease death and sudden cardiac death: a 20 year population study. Am. J. Epidemiol. 157(9), 763-770 (2003).
6. Ford ES, Ajani UA, Croft JB et al. Explaining the decrease in U.S. deaths from coronary disease, 1980-2000. N. Engl. J. Med. 356(23), 2388-2398 (2007).
7. Ridker PM, Danielson E, Fonseca FAH et al. Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N. Engl. J. Med. 359(21), 2195-2207 (2008).
8. Ridker PM, Hennekens CH, Buring JE, Rifai N. C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N. Engl. J. Med. 342(12), 836-843 (2000). (Pubitemid 30165206)
9. Arad Y, Goodman KJ, Roth M, Newstein D, Guerci AD. Coronary calcification, coronary risk factors, and atherosclerotic cardiovascular disease events. The St Francis Heart Study. J. Am. Coll. Cardiol. 46(1), 158-165 (2005).
10. Vliegenthart R, Oudkerk M, Hofman A et al. Coronary calcification improves cardiovascular risk prediction in the elderly. Circulation 112(4)572-577, 2005
11. Taylor AJ, Bindeman J, Feuerstein I, Cao F, Brazaitis M, O'Malley PG. Coronary calcium independently predicts incident premature coronary heart disease over measured cardiovascular risk factors. J. Am. Coll. Cardiol. 46(5), 807-814 (2005).
12. Budoff MJ, Shaw LJ, Liu ST et al. Long-term prognosis associated with coronary calcification: observations from a registry of 25,253 patients. J. Am. Coll. Cardiol. 49(18), 1860-1870 (2007).
13. Ridker PM, Rifai N, Rose L, Buring JE, Cook NR. Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N. Engl. J. Med. 347(20), 1557-1565 (2002).
14. Ridker PM, Buring JE, Rifai N, Cook NR. Development and validation of improved algorithms for the assessment of global cardiovascular risk in women: the Reynolds Risk Score. JAMA 297(6), 611-619 (2007).
15. Danesh J, Wheeler JG, Hirschfield GM et al. C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. N. Engl. J. Med. 350(14), 1387-1397 (2004).
16. Burke AP, Tracy RP, Kolodgie F et al. Elevated C-reactive protein values and atherosclerosis in sudden coronary death: association with different pathologies. Circulation 105(17), 2019-2023 (2002).
17. Park R, Detrano R, Xiang M et al. Combined use of computed tomography coronary calcium scores and C-reactive protein levels in predicting cardiovascular events in non-diabetic individuals. Circulation 106(16), 2073-2077 (2002).
18. Kathiresan S, Larson MG, Vasan RS et al. Contribution of clinical correlates and 13C-reactive protein gene polymorphisms to interindividual variability in serum C-reactive protein level. Circulation 113(11), 1415-1423 (2006).
19. Pradhan AD, Manson JE, Rifai N, Buring JE, Ridker PM. C-reactive protein, interleukin 6, and risk of developing Type 2 diabetes mellitus. JAMA 286(3), 327-334 (2001).
20. Barzilay JI, Abraham L, Heckbert SR et al. The relation of markers of inflammation to the development of glucose disorders in the elderly: the Cardiovascular Health Study. Diabetes 50(10), 2384-2389 (2001).
21. Engstrom G, Hedblad B, Stavenow L, Lind P, Janzon L, Lindgarde F. Inflammation- sensitive plasma proteins are associated with future weight gain. Diabetes 52, 2097-2101 (2003).
22. Engstrom G, Janzon L, Berglund G et al. Blood pressure increase and incidence of hypertension in relation to inflammation- sensitive plasma proteins. Arterioscler. Thromb. Vasc. Biol. 22(12), 2054-2058 (2002).
23. Sesso HD, Buring JE, Rifai N, Blake GJ, Gaziano JM, R idker PM. C -reactive protein and the risk of developing hypertension. JAMA 290(22), 2945-2951 (2003).
24. Ridker PM, Danielson E, Rifai N, Glynn RJ. Valsartan, blood pressure reduction, and C-reactive protein: primary report of the Val-MARC trial. Hypertension 48(1), 73-79 (2006).
25. Shah T, Casas JP, Cooper JA, Tzoulaki I, Sofat R, McCormack V et al. Critical appraisal of CRP measurement for the prediction of coronary heart disease events: new data and systematic review of 31 prospective cohorts. Int. J. Epidemiol. 38(1), 217-231 (2009).
26. Khera A, de Lemos JA, Peshock RM et al. Relationship between C-reactive protein and subclinical atherosclerosis: the Dallas Heart Study. Circulation 113(1), 38-43 (2006).
27. Rothenbacher D, Koenig W, Brenner H. Comparison of N-terminal pro-B- natriuretic peptide, C-reactive protein, and creatinine clearance for prognosis in patients with known coronary heart disease. Arch. Intern. Med. 116(22), 2455-2460 (2006).
28. Campbell DJ, Woodward M, Chalmers JP et al. Prediction of myocardial infarction by N-terminal-pro-B-type natriuretic peptide, C-reactive protein, and rennin in subjects with cerebrovascular disease. Circulation 112(29), 110-116 (2005). (Pubitemid 40962576)
29. Melander O, Newton-Cheh C, Almgren P et al. Novel and conventional biomarkers for prediction of incident cardiovascular events in the community. JAMA 302(1), 49-57 (2009).
30. Elliott P, Chambers JC, Zhang W et al. Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease. JAMA 302(1), 37-48 (2009).
31. Nordestgaard BG, Zacho J. Lipid, atherosclerosis and CVD risk: is CRP an innocent bystander? Nutr. Metab. Cardiovasc. Dis. 19(8), 521-524 (2009).
32. Zacho J, Tybjaerg-Hansen A, Jensen JS, Grande P, Sillesen H, Nordestgaard BG. Genetically elevated C-reactive protein and ischemic vascular disease. N. Engl. J. Med. 359(18), 1897-1908 (2008).
33. Cushman M, McClelland R, Folsom A et al. Inflammation factors, coronary calcium and risk of cardiovascular events: the Multi-Ethnic Study of Atherosclerosis (MESA). Presented at: American Heart Association Annual Scientific Sessions. Orlando, FL, USA, 4-7 November 2007.
34. Nasir K, Budoff MJ, Post WS et al. Electron beam CT vs. helical CT scans of coronary arteries: current utility and future directions. Am. Heart J. 146(6), 949-977.
35. Greenland P, Kizilbash MA. Coronary computed tomography in coronary risk assessment. J. Cardiopulm. Rehabil. 25(1), 3-10 (2005).
36. Gerber TC, Carr JJ, Arai AE et al. Ionizing radiation in cardiac imaging. A science advisory from the American Heart Association Committee on Cardiac Imaging of the Council of Clinical Cardiology and committee on cardiovascular imaging and intervention of the Council on cardiovascular radiology and intervention. Circulation 119(7), 1056-1065 (2009).
37. Horiguchi J, Matsuura N, Yamamoto H et al. Coronary artery calcium scoring on low-dose prospective electrocardiographically-triggered 64-slice CT. Acad Radiol. 16(2), 187-193 (2009).
38. Greenland P, LaBree L, Azen SP, Doherty TM, Detrano RC. Coronary artery calcium score combined with Framingham score for risk prediction in asymptomatic individuals. JAMA 291(2), 210-215.
39. Greenland P, Bonow RO, Brundage BH et al. ACCF/AHA 2007 clinical expert consensus document on coronary artery calcium scoring by computed tomography in global cardiovascular risk assessment and in evaluation of patients with chest pain: a report of the American College of Cardiology Foundation Clinical Expert Consensus Task Force developed in collaboration with the Society of Atherosclerosis Imaging and Prevention and the Society of Cardiovascular Computed Tomography. J. Am. Coll. Cardiol. 49(3), 378-402 (2007). (Pubitemid 46099075)
40. Raggi P, Callister TQ, Shaw LJ. Progression of coronary artery calcium and risk of first myocardial infarction in patients receiving cholesterol-lowering therapy. Arterioscler. Thromb. Vasc. Biol. 24(7), 1272-1277 (2004).
41. Taylor AJ, Bindeman J, Feuerstein I, Cao F, Brazaitis M, O'Malley PG. Coronary calcium independently predicts incident premature coronary heart disease over measured cardiovascular risk factors. J. Am. Coll. Cardiol. 46(5), 807-814 (2005).
42. Budoff MJ, Achenbach S, Blumenthal RS et al. Assessment of coronary artery disease by cardiac computed tomography, a scientific statement from the American Heart Association Committee on Cardiovascular Imaging and Intervention, Council on Cardiovascular Radiology and Intervention, and Committee on Cardiac Imaging, Council on Clinical Cardiology. Circulation 114(16), 1761-1791 (2006).
43. Arad Y, Spadaro LA, Roth M, Newstein D, Guerci AD. Treatment of asymptomatic adults with elevated coronary calcium scores with atorvastatin, vitamin C, and vitamin E: the St. Francis Heart Study randomized clinical trial. J. Am. Coll. Cardiol. 46(1), 166-172 (2005).
44. Achenbach S, Ropers D, Pohle K et al. Influence of lipid-lowering therapy on the progression of coronary artery calcification: a prospective evaluation. Circulation 106(9), 1077-1082 (2002).
45. Petranovic M, Soni A, Bezzera H et al. Assessment of nonstenotic coronary lesions by 64-slice multidetector computed tomography in comparison to intravascular ultrasound: evaluation of nonculprit coronary lesions. J. Cardiovasc. Comput. Tomogr. 3(1), 24-31 (2009).
46. Folsom AR, Kronmal R, Detrano RC et al. Coronary artery calcification compared with carotid intima-media thickness in prediction of cardiovascular disease incidence: The Multi-Ethnic Study of Atherosclerosis (MESA). Arch. Intern. Med. 168(12), 1333-1339 (2008).
47. Lorenz MW, Markus HS, Bots ML, Rosvall M, Sitzer M. Prediction of clinical cardiovascular events with carotid intima-media thickness: a systematic review and meta-analyses. Circulation 115(4), 459-467 (2007).
48. Anand DV, Lim E, Hopkins D et al. Risk stratification in uncomplicated Type 2 diabetes: prospective evaluation of the combined use of coronary artery calcium imaging and selective myocardial perfusion scintigraphy. Eur Heart J. 27(6), 713-721 (2006).
49. Becker A, Leber AW, Becker C et al. Predictive value of coronary calcifications for future cardiac events in asymptomatic patients with diabetes mellitus: a prospective study in 716 patients over 8 years. BMC Cardiovasc. Disord. 8(27), (2008).
50. Budoff MJ, Nasir K, McClelland RL et al. Coronary calcium predicts events better with absolute calcium scores than age-sex-race/ethnicity percentiles: MESA (Multi-Ethnic Study of Atherosclerosis). J. Am. Coll. Cardiol. 53(4), 345-352 (2009).
51. Erbel RA. Signs of subclinical coronary atherosclerosis measured as coronary artery calcification improve risk prediction of hard events beyond traditional risk factors in an unselected general population: The Heinz Nixdorf Recall Study five-year outcome data. Presented at: 58th Annual American College of Cardiology Scientific Sessions. Orlando, FL, USA, 29-31 March 2009.
52. Elias-Smale S, Proenca RV, Koller M et al. The impact of coronary calcium on assessment of coronary heart disease risk. J. Am. Coll. Cardiol. (2009) (In press).