Detailed haplotype-tagging study of germline variation of MUC19 in inflammatory bowel disease

Inflammatory Bowel Diseases

Volumn 16, Issue 4, 2010, Pages 557-558

  Phillips, Anne M ^a   Nimmo, Elaine R ^a   Van Limbergen, Johan ^a,b   Drummond, Hazel E ^a   Smith, Linda ^a   Satsangi, Jack ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

LEUCINE RICH REPEAT KINASE 2; MUCIN; MUCIN 19; UNCLASSIFIED DRUG;

CASE CONTROL STUDY; CHROMOSOME 12Q; COHORT ANALYSIS; CONTROLLED STUDY; CROHN DISEASE; ENTERITIS; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOME ANALYSIS; GENOTYPE; GENOTYPE PHENOTYPE CORRELATION; GERM LINE; HAPLOTYPE; HAPLOTYPE MAP; HUMAN; LETTER; MAJOR CLINICAL STUDY; PHENOTYPE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; ULCERATIVE COLITIS; UNITED KINGDOM;

CASE-CONTROL STUDIES; COHORT STUDIES; COLITIS, ULCERATIVE; CROHN DISEASE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GERM-LINE MUTATION; HAPLOTYPES; HUMANS; MUCINS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; PROTEIN-SERINE-THREONINE KINASES;

EID: 77949527614     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1002/ibd.21074     Document Type: Letter

References (8)

1. Rioux JD, Xavier RJ, Taylor KD, et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet. 2007;39:596-604.
2. The Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature. 2007;447: 661-678.
3. Barrett JC, Hansoul S, Nicolae DL, et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet. 2008;40: 955-962.
4. Hollingsworth MA, Swanson BJ. Mucins in cancer: protection and control of the cell surface. Nat Rev Cancer. 2004;4:45-60.
5. Van Limbergen J, Stevens C, Nimmo E, et al. Autophagy: from basic science to clinical application. Mucosal Immunol. 2009;2:315-330.
6. Silverberg MS, Satsangi J, Ahmad T, et al. Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology. Can J Gastroenterol. 2005;19:5A-36A.
7. Zimprich A, Biskup S, Leitner P, et al. Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. Neuron. 2004;44:601-607.
8. Plowey ED, Cherra SJ, Liu YJ, et al. Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells. J Neurochem. 2008;105:1048-1056.