Sclerocarya birrea (Anacardiaceae) stem-bark extract corrects glycaemia in diabetic rats and acts on β-cells by enhancing glucose-stimulated insulin secretion

Journal of Endocrinology

Volumn 205, Issue 1, 2010, Pages 79-86

  Ndifossap, Ivonne Gisèle Makom ^a,b   Frigerio, Francesca ^a   Casimir, Marina ^a   Tsofack, Florence Ngueguim ^b   Dongo, Etienne ^b   Kamtchouing, Pierre ^b   Dimo, Théophile ^b   Maechler, Pierre ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b UNIVERSITY OF YAOUNDÉ I   (Cameroon)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUCOSE; INSULIN; PLANT EXTRACT; SCLEROCARYA BIRREA EXTRACT; STREPTOZOCIN; UNCLASSIFIED DRUG;

ANACARDIACEAE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BARK; CELL DIFFERENTIATION; CELL ISOLATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG MECHANISM; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSE OXIDATION; INSULIN BLOOD LEVEL; INSULIN RELEASE; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; PLANT STEM; PRIORITY JOURNAL; RAT; SCLEROCARYA BIRREA; STREPTOZOCIN DIABETES;

ADENOSINE TRIPHOSPHATE; ANACARDIACEAE; ANIMALS; CELL LINE, TUMOR; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; GLUCOSE; HYPERGLYCEMIA; INSULIN; INSULIN-SECRETING CELLS; INSULINOMA; MALE; PANCREATIC NEOPLASMS; PLANT BARK; PLANT EXTRACTS; PLANT STEMS; RATS; RATS, WISTAR; STREPTOZOCIN;

EID: 77949516893     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1677/JOE-09-0311     Document Type: Article

References (22)

1. Altman SA, Randers L & Rao G 1993 Comparison of trypan blue dye exclusion and fluorometric assays for mammalian cell viability determinations. Biotechnology Progress 9 671-674.
2. de Andrade PB, Rubi B, Frigerio F, van den Ouweland JM, Maassen JA & Maechler P 2006 Diabetes-associated mitochondrial DNA mutation A3243G impairs cellular metabolic pathways necessary for beta cell function. Diabetologia 49 1816-1826.
3. Ashcroft FM 2006 K(ATP) channels and insulin secretion: a key role in health and disease. Biochemical Society Transactions 34 243-246.
4. Carobbio S, Ishihara H, Fernandez-Pascual S, Bartley C, Martin-Del-Rio R & Maechler P 2004 Insulin secretion profiles are modified by over-expression of glutamate dehydrogenase in pancreatic islets. Diabetologia 47 266-276.
5. Casimir M, Rubi B, Frigerio F, Chaffard G & Maechler P 2009 Silencing of the mitochondrial NADH shuttle component aspartate-glutamate carrier AGC1/Aralar1 in INS-1E cells and rat islets. Biochemical Journal 424 459-466.
6. Dieye AM, Sarr A, Diop SN, Ndiaye M, Sy GY, Diarra M, Rajraji Gaffary I, Ndiaye Sy A & Faye B 2008 Medicinal plants and the treatment of diabetes in Senegal: survey with patients. Fundamental & Clinical Pharmacology 22 211-216.
7. Dimo T, Rakotonirina SV, Tan PV, Azay J, Dongo E, Kamtchouing P & Cros G 2007 Effect of Sclerocarya birrea (Anacardiaceae) stem bark methylene chloride/methanol extract on streptozotocin-diabetic rats. Journal of Ethnopharmacology 110 434-438.
8. Eliasson L, Abdulkader F, Braun M, Galvanovskis J, Hoppa MB & Rorsman P 2008 Novel aspects of the molecular mechanisms controlling insulin secretion. Journal of Physiology 586 3313-3324.
9. Galvez Peralta J, Zarzuelo A, Busson R, Cobbaert C & de Witte P 1992 ( - )-Epicatechin-3-galloyl ester: a secretagogue compound from the bark of Sclerocarya birrea. Planta Medica 58 174-175.
10. Gill GV, Mbanya JC, Ramaiya KL & Tesfaye S 2009 A sub-Saharan African perspective of diabetes. Diabetologia 52 8-16.
11. Gondwe M, Kamadyaapa DR, Tufts M, Chuturgoon AA & Musabayane CT 2008 Sclerocarya birrea [(A. Rich.) Hochst.] [Anacardiaceae] stem-bark ethanolic extract (SBE) modulates blood glucose, glomerular filtration rate (GFR) and mean arterial blood pressure (MAP) of STZ-induced diabetic rats. Phytomedicine 15 699-709.
12. Iynedjian PB 2009 Molecular physiology of mammalian glucokinase. Cellular and Molecular Life Sciences 66 27-42.
13. 2+ and insulin secretion responses in the beta cell. Journal of Biological Chemistry 273 20770-20778.
14. Maechler P,Wang H &Wollheim CB 1998b Continuous monitoring of ATP levels in living insulin secreting cells expressing cytosolic firefly luciferase. FEBS Letters 422 328-332.
15. Maechler P, Carobbio S & Rubi B 2006 In beta-cells, mitochondria integrate and generate metabolic signals controlling insulin secretion. International Journal of Biochemistry & Cell Biology 38 696-709.
16. Merglen A, Theander S, Rubi B, Chaffard G, Wollheim CB & Maechler P 2004 Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells. Endocrinology 145 667-678.
17. Ojewole JA 2003 Hypoglycemic effect of Sclerocarya birrea [(A. Rich.) Hochst.] [Anacardiaceae] stem-bark aqueous extract in rats. Phytomedicine 10 675-681.
18. Ribble D, Goldstein NB, Norris DA & Shellman YG 2005 A simple technique for quantifying apoptosis in 96-well plates. BMC Biotechnology 5 12.
19. Rubi B, del Arco A, Bartley C, Satrustegui J & Maechler P 2004 The malate-aspartate NADH shuttle member Aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in beta cells. Journal of Biological Chemistry 279 55659-55666.
20. Rubi B, Ljubicic S, Pournourmohammadi S, Carobbio S, Armanet M, Bartley C & Maechler P 2005 Dopamine D2-like receptors are expressed in pancreatic beta cells and mediate inhibition of insulin secretion. Journal of Biological Chemistry 280 36824-36832.
21. Tsuneki H, Ishizuka M, Terasawa M, Wu JB, Sasaoka T & Kimura I 2004 Effect of green tea on blood glucose levels and serum proteomic patterns in diabetic (db/db) mice and on glucose metabolism in healthy humans. BMC Pharmacology 4 18.
22. van de Venter M, Roux S, Bungu LC, Louw J, Crouch NR, Grace OM, Maharaj V, Pillay P, Sewnarian P, Bhagwandin N et al. 2008 Antidiabetic screening and scoring of 11 plants traditionally used in South Africa. Journal of Ethnopharmacology 119 81-86.