메뉴 건너뛰기




Volumn 103, Issue 5, 2010, Pages 724-729

Comparison of (6S)-5-methyltetrahydrofolic acid v. folic acid as the reference folate in longer-term human dietary intervention studies assessing the relative bioavailability of natural food folates: Comparative changes in folate status following a 16-week placebo-controlled study in healthy adults

Author keywords

(6S) 5 methyltetrahydrofolic acid; Bioavailability; Folate; Folic acid; Human nutrition; Intervention studies; Plasma homocysteine

Indexed keywords

5 METHYLTETRAHYDROFOLIC ACID; CYANOCOBALAMIN; FOLIC ACID; HOMOCYSTEINE; METAFOLIN; PLACEBO; PYRIDOXINE; RIBOFLAVIN; UNCLASSIFIED DRUG; 5-METHYLTETRAHYDROFOLATE; TETRAHYDROFOLIC ACID DERIVATIVE; VITAMIN B COMPLEX;

EID: 77949510657     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114509992339     Document Type: Article
Times cited : (24)

References (30)
  • 1
    • 0025863475 scopus 로고
    • Prevention of neural tube defects: Results of the Medical Research Council Vitamin Study Medical Research Council Vitamin Study Research Group
    • Anonymous
    • Anonymous (1991) Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. Medical Research Council Vitamin Study Research Group. Lancet 338, 131-137.
    • (1991) Lancet , vol.338 , pp. 131-137
  • 2
    • 33845503323 scopus 로고    scopus 로고
    • Effects of folic acid supplementation on risk of cardiovascular diseases: A meta-analysis of randomised controlled trials
    • Bazzano LA, Reynolds K, Holder KN, et al. (2006) Effects of folic acid supplementation on risk of cardiovascular diseases: a meta-analysis of randomised controlled trials. JAMA 296, 2720-2726.
    • (2006) JAMA , vol.296 , pp. 2720-2726
    • Bazzano, L.A.1    Reynolds, K.2    Holder, K.N.3
  • 4
    • 0242610825 scopus 로고    scopus 로고
    • Role of folate in colon cancer development and progression
    • Kim Y-I (2003) Role of folate in colon cancer development and progression. J Nutr 133, 3731S-3739S.
    • (2003) J Nutr , vol.133
    • Kim, Y.-I.1
  • 5
    • 27744531050 scopus 로고    scopus 로고
    • The effect of folate fortification of cereal grain products on blood folate status, dietary folate intake and dietary folate sources among adult non-supplement users in the United States
    • Dietrich M, Brown CJ & Block G (2005) The effect of folate fortification of cereal grain products on blood folate status, dietary folate intake and dietary folate sources among adult non-supplement users in the United States. J Am Coll Nutr 24, 266-274.
    • (2005) J Am Coll Nutr , vol.24 , pp. 266-274
    • Dietrich, M.1    Brown, C.J.2    Block, G.3
  • 6
    • 20044394752 scopus 로고    scopus 로고
    • Reduction of birth prevalence rates of neural tube defects after folic acid fortification in Chile
    • Lopez-Camelo JS, Orioli M, de Graca Dutra M, et al. (2005) Reduction of birth prevalence rates of neural tube defects after folic acid fortification in Chile. Am J Med Genet A 135, 120-125.
    • (2005) Am J Med Genet A , vol.135 , pp. 120-125
    • Lopez-Camelo, J.S.1    Orioli, M.2    De Graca Dutra, M.3
  • 7
    • 34447342598 scopus 로고    scopus 로고
    • Reduction in neural tube defects after folate fortification in Canada
    • De Wals P, Tairou F, van Allen MI, et al. (2007) Reduction in neural tube defects after folate fortification in Canada. New Eng J Med 357, 135-142.
    • (2007) New Eng J Med , vol.357 , pp. 135-142
    • De Wals, P.1    Tairou, F.2    Van Allen, M.I.3
  • 8
  • 9
    • 0043156139 scopus 로고    scopus 로고
    • Folate bioavailability: UK Food Standards Agency workshop report
    • Sanderson P, McNulty H, Mastroiacovo P, et al. (2003) Folate bioavailability: UK Food Standards Agency workshop report. Br J Nutr 90, 473-479.
    • (2003) Br J Nutr , vol.90 , pp. 473-479
    • Sanderson, P.1    McNulty, H.2    Mastroiacovo, P.3
  • 10
    • 0021352480 scopus 로고
    • Mechanisms of folate homeostasis
    • Steinberg SE (1984) Mechanisms of folate homeostasis. Am J Physiol 246, G319-G324.
    • (1984) Am J Physiol , vol.246
    • Steinberg, S.E.1
  • 11
    • 0035071706 scopus 로고    scopus 로고
    • Case study: Folate bioavailability
    • Gregory JF (2001) Case study: folate bioavailability. J Nutr 131, 1376S-1382S.
    • (2001) J Nutr , vol.131
    • Gregory, J.F.1
  • 12
    • 0042062309 scopus 로고    scopus 로고
    • 13C forms of pteroylmonoglutamic acid and 5-formyltetra-hydrofolic acid elicit differences in short-term kinetics of labelled and unlabelled folates in plasma: Potential problems in interpretation of folate bioavailability studies
    • 13C forms of pteroylmonoglutamic acid and 5-formyltetra-hydrofolic acid elicit differences in short-term kinetics of labelled and unlabelled folates in plasma: potential problems in interpretation of folate bioavailability studies. Br J Nutr 90, 363-371.
    • (2003) Br J Nutr , vol.90 , pp. 363-371
    • Wright, A.J.A.1    Finglas, P.M.2    Dainty, J.R.3
  • 13
    • 14944357665 scopus 로고    scopus 로고
    • Differential kinetic behaviour and distribution for pteroylmonoglutamic acid and reduced folates: A revised hypothesis of the primary site of PteGlu metabolism in humans
    • Wright AJA, Finglas PM, Dainty JR, et al. (2005) Differential kinetic behaviour and distribution for pteroylmonoglutamic acid and reduced folates: a revised hypothesis of the primary site of PteGlu metabolism in humans. J Nutr 135, 619-623.
    • (2005) J Nutr , vol.135 , pp. 619-623
    • Wright, A.J.A.1    Finglas, P.M.2    Dainty, J.R.3
  • 14
    • 34748912412 scopus 로고    scopus 로고
    • Folic acid metabolism in human subjects revisited: Potential implications for proposed mandatory folic acid fortification in the UK
    • Wright AJA, Dainty JR & Finglas PM (2007) Folic acid metabolism in human subjects revisited: potential implications for proposed mandatory folic acid fortification in the UK. Br J Nutr 98, 667-675.
    • (2007) Br J Nutr , vol.98 , pp. 667-675
    • Wright, A.J.A.1    Dainty, J.R.2    Finglas, P.M.3
  • 15
    • 0000143003 scopus 로고    scopus 로고
    • Folic acid
    • 9th ed. [ME Shils, JA Olson, M Shike and AC Ross, editors]. Baltimore: MD, Williams & Wilkins
    • Herbert V (1999) Folic acid. In Modern Nutrition in Health and Disease, 9th ed., pp. 433-446 [ME Shils, JA Olson, M Shike and AC Ross, editors]. Baltimore: MD, Williams & Wilkins.
    • (1999) In Modern Nutrition in Health and Disease , pp. 433-446
    • Herbert, V.1
  • 16
    • 0036399750 scopus 로고    scopus 로고
    • In vivo kinetics of folate metabolism
    • Gregory JF & Quinlivan EP (2002) In vivo kinetics of folate metabolism. Annu Rev Nutr 22, 199-220.
    • (2002) Annu Rev Nutr , vol.22 , pp. 199-220
    • Gregory, J.F.1    Quinlivan, E.P.2
  • 17
    • 0021352480 scopus 로고
    • Mechanisms of folate homeostasis
    • Steinberg SE (1984) Mechanisms of folate homeostasis. Am J Physiol 246, G319-G324.
    • (1984) Am J Physiol , vol.246
    • Steinberg, S.E.1
  • 18
    • 0030962568 scopus 로고    scopus 로고
    • Unmetabolised folic acid in serum: Acute studies in subjects consuming fortified foods and supplements
    • Kelly P, McPartlin J, Goggins M, et al. (1997) Unmetabolised folic acid in serum: acute studies in subjects consuming fortified foods and supplements. Am J Clin Nutr 65, 1790-1795.
    • (1997) Am J Clin Nutr , vol.65 , pp. 1790-1795
    • Kelly, P.1    McPartlin, J.2    Goggins, M.3
  • 19
    • 34047122671 scopus 로고    scopus 로고
    • Folic acid fortification and public health: Report on threshold above which unmetabolised folic acid appear in serum
    • Sweeney MA, McPartlin J & Scott J (2007) Folic acid fortification and public health: report on threshold above which unmetabolised folic acid appear in serum. BMC Public Health 7, 41.
    • (2007) BMC Public Health , vol.7 , pp. 41
    • Sweeney, M.A.1    McPartlin, J.2    Scott, J.3
  • 21
    • 0026544977 scopus 로고
    • Microbiological assay on microtitre plates of folate in serum and red cells
    • O'Broin SO & Kelleher B (1992) Microbiological assay on microtitre plates of folate in serum and red cells. J Clin Path 45, 344-347.
    • (1992) J Clin Path , vol.45 , pp. 344-347
    • O'Broin, S.O.1    Kelleher, B.2
  • 22
    • 0033634904 scopus 로고    scopus 로고
    • Erythrocyte folate analysis: Saponin added during lysis of whole blood can increase apparent folate concentrations, depending on hemolysate pH
    • Wright AJA, Finglas PM & Southon S (2000) Erythrocyte folate analysis: saponin added during lysis of whole blood can increase apparent folate concentrations, depending on hemolysate pH. Clin Chem 46, 1978-1986
    • (2000) Clin Chem , vol.46 , pp. 1978-1986
    • Wright, A.J.A.1    Finglas, P.M.2    Southon, S.3
  • 23
    • 0026294367 scopus 로고
    • Dietary reference values for food energy and nutrients for the United Kingdom
    • Department of Health London: H.M. Stationery Office
    • Department of Health (1991) Dietary Reference Values for Food Energy and Nutrients for the United Kingdom. Report on Health and Social Subjects no. 41. London: H.M. Stationery Office.
    • (1991) Report on Health and Social Subjects No. 41
  • 24
    • 0029040493 scopus 로고
    • Results of B-vitamin supplementation study used in a prediction model to define a reference range for plasma homocysteine
    • Ubbink JB, Becker PJ, Vermask WJH, et al. (1995) Results of B-vitamin supplementation study used in a prediction model to define a reference range for plasma homocysteine. Clin Chem 41, 1033-1037.
    • (1995) Clin Chem , vol.41 , pp. 1033-1037
    • Ubbink, J.B.1    Becker, P.J.2    Vermask, W.J.H.3
  • 25
    • 0242649420 scopus 로고
    • Assessment of the status of folate and vitamin B-12
    • chapter 22 [RS Gibson, editor]. Oxford: Oxford University Press
    • Gibson RS (1990) Assessment of the status of folate and vitamin B-12. In Principles of Nutritional Assessment, chapter 22, pp. 461-486 [RS Gibson, editor]. Oxford: Oxford University Press.
    • (1990) In Principles of Nutritional Assessment , pp. 461-486
    • Gibson, R.S.1
  • 26
    • 0036847277 scopus 로고    scopus 로고
    • Increases in blood folate indices are similar in women of childbearing age supplemented with [6S]-5-methyltetrahydrofolate and folic acid
    • Venn BJ, Green TJ, Moser R, et al. (2002) Increases in blood folate indices are similar in women of childbearing age supplemented with [6S]-5-methyltetrahydrofolate and folic acid. J Nutr 132, 3353-3355.
    • (2002) J Nutr , vol.132 , pp. 3353-3355
    • Venn, B.J.1    Green, T.J.2    Moser, R.3
  • 27
    • 0037371082 scopus 로고    scopus 로고
    • Comparison of the effect of low-dose supplementation with L-5-methyltetra-hydrofolate or folic acid on plasma homocysteine: A randomised placebo-controlled study
    • Venn BJ, Green TJ, Moser R, et al. (2003) Comparison of the effect of low-dose supplementation with L-5-methyltetra-hydrofolate or folic acid on plasma homocysteine: a randomised placebo-controlled study. Am J Clin Nutr 77, 658-662.
    • (2003) Am J Clin Nutr , vol.77 , pp. 658-662
    • Venn, B.J.1    Green, T.J.2    Moser, R.3
  • 28
    • 33646705408 scopus 로고    scopus 로고
    • [6S]-5-methyltetrahydrofolate is at least as effective as folic acid in preventing a decline in blood folate concentrations during lactation
    • Houghton LA, Sherwood KL, Pawlosky R, et al. (2006) [6S]-5- methyltetrahydrofolate is at least as effective as folic acid in preventing a decline in blood folate concentrations during lactation. Am J Clin Nutr 83, 842-850.
    • (2006) Am J Clin Nutr , vol.83 , pp. 842-850
    • Houghton, L.A.1    Sherwood, K.L.2    Pawlosky, R.3
  • 29
    • 33747418536 scopus 로고    scopus 로고
    • Red blood cell folate concentrations increase more after supplementation with [6S]-5-methyltetrahydrofolate than with folic acid in women of childbearing age
    • Lamers Y, Prinz-Langenohl R, Bramswig S, et al. (2006) Red blood cell folate concentrations increase more after supplementation with [6S]-5-methyltetrahydrofolate than with folic acid in women of childbearing age. Am J Clin Nutr 84, 156-161.
    • (2006) Am J Clin Nutr , vol.84 , pp. 156-161
    • Lamers, Y.1    Prinz-Langenohl, R.2    Bramswig, S.3
  • 30
    • 18344389163 scopus 로고    scopus 로고
    • A European multicentre, placebo controlled supplementation study with a-tocopherol, carotene-rich palm oil, lutein or lycopene: Analysis of serum responses
    • Olmedilla B, Granado F, Southon S, et al. (2002) A European multicentre, placebo controlled supplementation study with a-tocopherol, carotene-rich palm oil, lutein or lycopene: analysis of serum responses. Clin Sci 102, 447-456.
    • (2002) Clin Sci , vol.102 , pp. 447-456
    • Olmedilla, B.1    Granado, F.2    Southon, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.