Inflammatory Protein Serum Amyloid A1 Marks a Subset of Conventional Renal Cell Carcinomas with Fatal Outcome

European Urology

Volumn 57, Issue 5, 2010, Pages 859-866

  Paret, Claudia ^a   Schön, Zorica ^a   Szponar, Adrianna ^a   Kovacs, Gyula ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Conventional RCC; Metastasis; MMP; SAA1; TMA

Indexed keywords

GELATINASE B; SERUM AMYLOID A; SERUM AMYLOID A1; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER CELL CULTURE; CANCER CLASSIFICATION; CANCER INVASION; CANCER SURVIVAL; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FOLLOW UP; GENE EXPRESSION; GENE IDENTIFICATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KIDNEY CARCINOMA; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ANALYSIS; TISSUE MICROARRAY; ZYMOGRAPHY;

ADULT; AGED; BIOLOGICAL MARKERS; CARCINOMA, RENAL CELL; FEMALE; HUMANS; KIDNEY NEOPLASMS; MALE; MIDDLE AGED; PROGNOSIS; SERUM AMYLOID A PROTEIN;

EID: 77949488296     PISSN: 03022838     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eururo.2009.08.014     Document Type: Article

References (25)

1. Zisman A., Pantuck A.J., Wieder J., et al. Risk group assessment and clinical outcome algorithm to predict the natural history of patients with surgically resected renal cell carcinoma. J Clin Oncol 20 (2002) 4559-4566
2. Motzer R.J., and Russo P. Systemic therapy for renal cell carcinoma. J Urol 163 (2000) 408-417
3. Kimura M., Tomita Y., Imai T., et al. Significance of serum amyloid A on the prognosis in patients with renal cell carcinoma. Cancer 92 (2001) 2072-2075
4. Ramankulov A., Lein M., Johannsen M., et al. Serum amyloid A as indicator of distant metastases but not as early tumour marker in patients with renal cell carcinoma. Cancer Lett 269 (2008) 85-92
5. Urieli-Shoval S., Linke R.P., and Matzner Y. Expression and function of serum amyloid A, a major acute-phase protein, in normal and disease states. Curr Opin Hematol 7 (2000) 64-69
6. Betts J.C., Edbrooke M.R., Thakker R.V., and Woo P. The human acute-phase serum amyloid A gene family: structure, evolution and expression in hepatoma cells. Scand J Immunol 34 (1991) 471-482
7. He R., Sang H., and Ye R.D. Serum amyloid A induces IL-8 secretion through a G protein-coupled receptor, FPRL1/LXA4R. Blood 101 (2003) 1572-1581
8. Xu L., Badolato R., Murphy W.J., et al. A novel biologic function of serum amyloid A. Induction of T lymphocyte migration and adhesion. J Immunol 155 (1995) 1184-1190
9. Ancsin J.B., and Kisilevsky R. Characterization of High Affinity Binding between Laminin and the Acute-phase Protein, Serum Amyloid A. J Biol Chem 272 (1997) 406-413
10. Lee H.Y., Kim M.K., Park K.S., et al. Serum amyloid A stimulates matrix-metalloproteinase-[9] upregulation via formyl peptide receptor like-1-mediated signaling in human monocytic cells. Biochem Biophys Res Commun 330 (2005) 989-998
11. O'Hara R., Murphy E.P., Whitehead A.S., FitzGerald O., and Bresnihan B. Local expression of the serum amyloid A and formyl peptide receptor-like 1 genes in synovial tissue is associated with matrix metalloproteinase production in patients with inflammatory arthritis. Arthritis Rheum 50 (2004) 1788-1799
12. Migita K., Kawabe Y., Tominaga M., Origuchi T., Aoyagi T., and Eguchi K. Serum amyloid A protein induces production of matrix metalloproteinases by human synovial fibroblasts. Lab Invest 78 (1998) 535-539
13. Bjorklund M., and Koivunen E. Gelatinase-mediated migration and invasion of cancer cells. Biochim Biophys Acta 1755 (2005) 37-69
14. Bhuvarahamurthy V., Kristiansen G.O., Johannsen M., et al. In situ gene expression and localization of metalloproteinases MMP1, MMP2, MMP3, MMP9, and their inhibitors TIMP1 and TIMP2 in human renal cell carcinoma. Oncol Rep 15 (2006) 1379-1384
15. Cho N.H., Shim H.S., Rha S.Y., et al. Increased expression of matrix metalloproteinase 9 correlates with poor prognostic variables in renal cell carcinoma. Eur Urol 44 (2003) 560-566
16. Kovacs G., Akhtar M., Beckwith B.J., et al. The Heidelberg classification of renal cell tumours. J Pathol 183 (1997) 131-133
17. Subramanian A., Tamayo P., Mootha V.K., et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A 102 (2005) 15545-15550
18. Kovacs G., and Frisch S. Clonal chromosome abnormalities in tumor cells from patients with sporadic renal cell carcinomas. Cancer Res 49 (1989) 651-659
19. Uhlar C.M., and Whitehead A.S. Serum amyloid A, the major vertebrate acute-phase reactant. Eur J Biochem 265 (1999) 501-523
20. Jabs W.J., Busse M., Krüger S., Jocham D., Steinhoff J., and Doehn C. Expression of C-reactive protein by renal cell carcinomas and unaffected surrounding renal tissue. Kidney Int 68 (2005) 2103-2110
21. Karakiewicz P.I., Hutterer G.C., Trinh Q.D., et al. C-reactive protein is an informative predictor of renal cell carcinoma-specific mortality: a European study of 313 patients. Cancer 110 (2007) 1241-1247
22. Bannikov G.A., Karelina T.V., Collier I.E., Marmer B.L., and Goldberg G.I. Substrate binding of gelatinase B induces its enzymatic activity in the presence of intact propeptide. J Biol Chem 277 (2002) 16022-16027
23. Cai L., de Beer M.C., de Beer F.C., and van der Westhuyzen D.R. Serum amyloid A is a ligand for scavenger receptor class B type I and inhibits high density lipoprotein binding and selective lipid uptake. J Biol Chem 280 (2005) 2954-2961
24. Cheng N., He R., Tian J., Ye P.P., and Ye R.D. Cutting edge: TLR2 is a functional receptor for acute-phase serum amyloid A. J Immunol 181 (2008) 22-26
25. Okamoto H., Katagiri Y., Kiire A., Momohara S., and Kamatani N. Serum amyloid A activates nuclear factor-kappaB in rheumatoid synovial fibroblasts through binding to receptor of advanced glycation end-products. J Rheumatol 35 (2008) 752-756