Investigation of mitochondrial sequence variants associated with aminoglycoside-induced ototoxicity in South African TB patients on aminoglycosides

Biochemical and Biophysical Research Communications

Volumn 393, Issue 4, 2010, Pages 751-756

  Human, Hanniqué ^a   Hagen, Christian M ^b   Jong, Greetje de ^a   Harris, Tashneem ^c   Lombard, Debbie ^a   Christiansen, Michael ^b   Bardien, Soraya ^a  

^a STELLENBOSCH UNIVERSITY   (South Africa)

^b STATENS SERUM INSTITUT   (Denmark)

^c UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

961delT+insC(n); A1555G; A827G; Aminoglycoside induced hearing loss; Multi drug resistant TB; SNaPshot technique; T961G

Indexed keywords

AMINOGLYCOSIDE;

ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; GENE MUTATION; GENE SEQUENCE; GENETIC VARIABILITY; GNETOPHYTA; HUMAN; MAJOR CLINICAL STUDY; MITOCHONDRIAL MEMBRANE; MT RNR1 GENE; OTOTOXICITY; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; TUBERCULOSIS;

AMINOGLYCOSIDES; ANTIBIOTICS, ANTITUBERCULAR; BASE SEQUENCE; DNA MUTATIONAL ANALYSIS; FEMALE; GENES, MITOCHONDRIAL; GENETIC TESTING; HEARING LOSS; HUMANS; MALE; MOLECULAR SEQUENCE DATA; SOUTH AFRICA; TUBERCULOSIS, MULTIDRUG-RESISTANT;

EID: 77949488211     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.02.075     Document Type: Article

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