Very low penetrance of hearing loss in seven Han Chinese pedigrees carrying the deafness-associated 12S rRNA A1555G mutation

Gene

Volumn 393, Issue 1-2, 2007, Pages 11-19

  Tang, Xiaowen ^a   Yang, Li ^b   Zhu, Yi ^a   Liao, Zhisu ^a   Wang, Jindan ^a   Qian, Yaping ^b   Tao, Zhihua ^a   Hu, Lenong ^c   Wu, Guomin ^d   Lan, Jinshan ^e   Wang, Xinjian ^b   Ji, Jingzhang ^a   Wu, Jian ^f   Ji, Yu ^g   Feng, Jinbao ^h   Chen, Jianfu ^a   Li, Zhiyuan ^a   Zhang, Xue ⁱ   Lu, Jianxin ^a   Guan, Min Xin ^a,b,j  

^a WENZHOU MEDICAL UNIVERSITY   (China)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^c LISHUI CENTRAL HOSPITAL   (China)

^d TAIZHOU HOSPITAL OF ZHEJIANG PROVINCE   (China)

^e Quzhou People's Hospital   (China)

^f Lishui Special Education School   (China)

^g Linhai Special Education School   (China)

^h Quzhou Special Education School   (China)

ⁱ PEKING UNION MEDICAL COLLEGE   (China)

^j UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

more..

Author keywords

12S rRNA; Chinese; Hearing loss; Mitochondrial haplogroup; Mutation; Penetrance

Indexed keywords

AMINOGLYCOSIDE; GENTAMICIN; MITOCHONDRIAL DNA; RIBOSOME RNA; STREPTOMYCIN;

ARTICLE; AUDIOMETRY; CLINICAL ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; DNA SEQUENCE; FEMALE; GENE AMPLIFICATION; GENE EXPRESSION; GENE MUTATION; GENE SEQUENCE; HAPLOTYPE; HEARING IMPAIRMENT; HEARING LOSS; HUMAN; MALE; MENINGITIS; MISSENSE MUTATION; NUCLEOTIDE SEQUENCE; PEDIGREE; PHENOTYPE; PRIORITY JOURNAL;

ADENINE; ADOLESCENT; ADULT; AMINOGLYCOSIDES; ASIAN CONTINENTAL ANCESTRY GROUP; CHILD; CHINA; CONNEXINS; DEAFNESS; DNA MUTATIONAL ANALYSIS; DNA, MITOCHONDRIAL; FEMALE; GENOME, HUMAN; GUANINE; HEARING LOSS, BILATERAL; HUMANS; MALE; MUTATION; PEDIGREE; PENETRANCE; RNA, RIBOSOMAL;

EID: 34047266817     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2007.01.001     Document Type: Article

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