-
1
-
-
64549161956
-
Treatment options in patients with rheumatoid arthritis failing initial TNF inhibitor therapy: A critical review
-
Rubbert-Roth A, Finckh A. Treatment options in patients with rheumatoid arthritis failing initial TNF inhibitor therapy: a critical review. Arthritis Res Ther. 2009;11 Suppl 1:S1.
-
(2009)
Arthritis Res Ther.
, vol.11
, Issue.SUPPL. 1
-
-
Rubbert-Roth, A.1
Finckh, A.2
-
2
-
-
0022441214
-
Tumour necrosis factor alpha stimulates resorption and inhibits synthesis of proteoglycan in cartilage
-
Aug 7-13
-
Saklatvala J. Tumour necrosis factor alpha stimulates resorption and inhibits synthesis of proteoglycan in cartilage. Nature. 1986 Aug 7-13; 322(6079):547-549.
-
(1986)
Nature
, vol.322
, Issue.6079
, pp. 547-549
-
-
Saklatvala, J.1
-
3
-
-
0034773340
-
Anti-TNF therapy for rheumatoid arthritis and other inflammatory diseases
-
Oct
-
Taylor PC. Anti-TNF therapy for rheumatoid arthritis and other inflammatory diseases. Mol Biotechnol. 2001 Oct;19(2):153-168.
-
(2001)
Mol Biotechnol.
, vol.19
, Issue.2
, pp. 153-168
-
-
Taylor, P.C.1
-
4
-
-
33644895018
-
Predictors of joint damage in patients with early rheumatoid arthritis treated with high-dose methotrexate with or without concomitant infliximab: Results from the ASPIRE trial
-
Smolen JS, Van Der Heijde DM, St Clair EW, et al. Predictors of joint damage in patients with early rheumatoid arthritis treated with high-dose methotrexate with or without concomitant infliximab: results from the ASPIRE trial. Arthritis Rheum. 2006;54(3):702-710.
-
(2006)
Arthritis Rheum.
, vol.54
, Issue.3
, pp. 702-710
-
-
Smolen, J.S.1
van der Heijde, D.M.2
St Clair, E.W.3
-
5
-
-
9144264155
-
Infliximab in active early rheumatoid arthritis
-
Breedveld FC, Emery P, Keystone E, et al. Infliximab in active early rheumatoid arthritis. Ann Rheum Dis. 2004;63(2):149-155.
-
(2004)
Ann Rheum Dis.
, vol.63
, Issue.2
, pp. 149-155
-
-
Breedveld, F.C.1
Emery, P.2
Keystone, E.3
-
6
-
-
33750717549
-
Aiming at low disease activity in rheumatoid arthritis with initial combination therapy or initial monotherapy strategies: The BeSt study
-
Allaart CF, Goekoop-Ruiterman YP, de Vries-Bouwstra JK, Breedveld FC, Dijkmans BA. Aiming at low disease activity in rheumatoid arthritis with initial combination therapy or initial monotherapy strategies: the BeSt study. Clin Exp Rheumatol. 2006;24(6 Suppl 43):S77-S82.
-
(2006)
Clin Exp Rheumatol.
, vol.24
, Issue.6 SUPPL. 43
-
-
Allaart, C.F.1
Goekoop-Ruiterman, Y.P.2
de Vries-Bouwstra, J.K.3
Breedveld, F.C.4
Dijkmans, B.A.5
-
7
-
-
19944431840
-
Very early treatment with infliximab in addition to methotrexate in early, poor-prognosis rheumatoid arthritis reduces magnetic resonance imaging evidence of synovitis and damage, with sustained benefit after infliximab withdrawal: Results from a twelve-month randomized, double-blind, placebo-controlled trial
-
Quinn MA, Conaghan PG, O'Connor PJ, et al. Very early treatment with infliximab in addition to methotrexate in early, poor-prognosis rheumatoid arthritis reduces magnetic resonance imaging evidence of synovitis and damage, with sustained benefit after infliximab withdrawal: results from a twelve-month randomized, double-blind, placebo-controlled trial. Arthritis Rheum. 2005;52(1):27-35.
-
(2005)
Arthritis Rheum.
, vol.52
, Issue.1
, pp. 27-35
-
-
Quinn, M.A.1
Conaghan, P.G.2
O'Connor, P.J.3
-
8
-
-
72249085325
-
Bone loss in active early rheumatoid arthritis patients treated with infliximab and methotrexate compared with methotrexate treatment alone. Explorative analysis from a twelve-month randomized, double blind, placebo-controlled study
-
Apr 21. [Epub ahead of print]
-
Haugeberg G, Conaghan PG, Quinn M, Emery P. Bone loss in active early rheumatoid arthritis patients treated with infliximab and methotrexate compared with methotrexate treatment alone. Explorative analysis from a twelve-month randomized, double blind, placebo-controlled study. Ann Rheum Dis. 2009. Apr 21. [Epub ahead of print].
-
(2009)
Ann Rheum Dis.
-
-
Haugeberg, G.1
Conaghan, P.G.2
Quinn, M.3
Emery, P.4
-
9
-
-
1642494799
-
Effector cell-derived lymphotoxin alpha and Fas ligand, but not perforin, promote Tc1 and Tc2 effector cell-mediated tumor therapy in established pulmonary metastases
-
Dobrzanski MJ, Reome JB, Hollenbaugh JA, Hylind JC, Dutton RW. Effector cell-derived lymphotoxin alpha and Fas ligand, but not perforin, promote Tc1 and Tc2 effector cell-mediated tumor therapy in established pulmonary metastases. Cancer Res. 2004;64(1):406-414.
-
(2004)
Cancer Res.
, vol.64
, Issue.1
, pp. 406-414
-
-
Dobrzanski, M.J.1
Reome, J.B.2
Hollenbaugh, J.A.3
Hylind, J.C.4
Dutton, R.W.5
-
10
-
-
14044264198
-
Role of biological agents in immunemediated inflammatory diseases
-
Efthimiou P, Markenson JA. Role of biological agents in immunemediated inflammatory diseases. South Med J. 2005;98(2):192-204.
-
(2005)
South Med J.
, vol.98
, Issue.2
, pp. 192-204
-
-
Efthimiou, P.1
Markenson, J.A.2
-
11
-
-
0013511183
-
Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein
-
Moreland LW, Baumgartner SW, Schiff MH, et al. Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein. N Engl J Med. 1997;337(3):141-147.
-
(1997)
N Engl J Med.
, vol.337
, Issue.3
, pp. 141-147
-
-
Moreland, L.W.1
Baumgartner, S.W.2
Schiff, M.H.3
-
12
-
-
0033574147
-
Etanercept therapy in rheumatoid arthritis. A randomized, controlled trial
-
Moreland LW, Schiff MH, Baumgartner SW, et al. Etanercept therapy in rheumatoid arthritis. A randomized, controlled trial. Ann Intern Med. 1999;130(6):478-486.
-
(1999)
Ann Intern Med.
, vol.130
, Issue.6
, pp. 478-486
-
-
Moreland, L.W.1
Schiff, M.H.2
Baumgartner, S.W.3
-
13
-
-
48149100741
-
Comparison of methotrexate monotherapy with a combination of methotrexate and etanercept in active, early, moderate to severe rheumatoid arthritis (COMET): A randomised, double-blind, parallel treatment trial
-
Emery P, Breedveld FC, Hall S, et al. Comparison of methotrexate monotherapy with a combination of methotrexate and etanercept in active, early, moderate to severe rheumatoid arthritis (COMET): a randomised, double-blind, parallel treatment trial. Lancet. 2008; 372(9636):375-382.
-
(2008)
Lancet.
, vol.372
, Issue.9636
, pp. 375-382
-
-
Emery, P.1
Breedveld, F.C.2
Hall, S.3
-
14
-
-
10744223002
-
Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: Double-blind randomised controlled trial
-
Klareskog L, van der Heijde D, de Jager JP, et al. Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: double-blind randomised controlled trial. Lancet. 2004;363(9410):675-681.
-
(2004)
Lancet.
, vol.363
, Issue.9410
, pp. 675-681
-
-
Klareskog, L.1
van der Heijde, D.2
de Jager, J.P.3
-
15
-
-
70350651605
-
Perceived work ability, quality of life, and fatigue in patients with rheumatoid arthritis after a 6-month course of TNF inhibitors: Prospective intervention study and partial economic evaluation
-
Hoving JL, Bartelds GM, Sluiter JK, et al. Perceived work ability, quality of life, and fatigue in patients with rheumatoid arthritis after a 6-month course of TNF inhibitors: prospective intervention study and partial economic evaluation. Scand J Rheumatol. 2009:1-5.
-
(2009)
Scand J Rheumatol.
, pp. 1-5
-
-
Hoving, J.L.1
Bartelds, G.M.2
Sluiter, J.K.3
-
16
-
-
31044442965
-
The PREMIER study: A multicenter, randomized, double-blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment
-
Breedveld FC, Weisman MH, Kavanaugh AF, et al. The PREMIER study: A multicenter, randomized, double-blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment. Arthritis Rheum. 2006;54(1):26-37.
-
(2006)
Arthritis Rheum.
, vol.54
, Issue.1
, pp. 26-37
-
-
Breedveld, F.C.1
Weisman, M.H.2
Kavanaugh, A.F.3
-
17
-
-
65549106396
-
Randomized, Double-blind, Placebo-controlled, Comparative Study of Human Anti-TNF Antibody Adalimumab in Combination with Methotrexate and Methotrexate Alone in Taiwanese Patients with Active Rheumatoid Arthritis
-
Chen DY, Chou SJ, Hsieh TY, et al. Randomized, Double-blind, Placebo-controlled, Comparative Study of Human Anti-TNF Antibody Adalimumab in Combination with Methotrexate and Methotrexate Alone in Taiwanese Patients with Active Rheumatoid Arthritis. J Formos Med Assoc. 2009;108(4):310-319.
-
(2009)
J Formos Med Assoc.
, vol.108
, Issue.4
, pp. 310-319
-
-
Chen, D.Y.1
Chou, S.J.2
Hsieh, T.Y.3
-
18
-
-
33744479185
-
Long term efficacy and safety of adalimumab plus methotrexate in patients with rheumatoid arthritis: ARMADA 4 year extended study
-
Weinblatt ME, Keystone EC, Furst DE, Kavanaugh AF, Chartash EK, Segurado OG. Long term efficacy and safety of adalimumab plus methotrexate in patients with rheumatoid arthritis: ARMADA 4 year extended study. Ann Rheum Dis. 2006;65(6):753-759.
-
(2006)
Ann Rheum Dis.
, vol.65
, Issue.6
, pp. 753-759
-
-
Weinblatt, M.E.1
Keystone, E.C.2
Furst, D.E.3
Kavanaugh, A.F.4
Chartash, E.K.5
Segurado, O.G.6
-
19
-
-
51549119395
-
A PEGylated Fab' fragment against tumor necrosis factor for the treatment of Crohn disease: Exploring a new mechanism of action
-
Bourne T, Fossati G, Nesbitt A. A PEGylated Fab' fragment against tumor necrosis factor for the treatment of Crohn disease: exploring a new mechanism of action. BioDrugs. 2008;22(5):331-337.
-
(2008)
BioDrugs.
, vol.22
, Issue.5
, pp. 331-337
-
-
Bourne, T.1
Fossati, G.2
Nesbitt, A.3
-
20
-
-
67449124634
-
Efficacy and Safety of Certolizumab Pegol Plus Methotrexate in Active Rheumatoid Arthritis: The RAPID 2 Study
-
Smolen JS, Landewe RB, Mease PJ, et al. Efficacy and Safety of Certolizumab Pegol Plus Methotrexate in Active Rheumatoid Arthritis: The RAPID 2 Study. Ann Rheum Dis. 2009;68(6):797-804.
-
(2009)
Ann Rheum Dis.
, vol.68
, Issue.6
, pp. 797-804
-
-
Smolen, J.S.1
Landewe, R.B.2
Mease, P.J.3
-
21
-
-
55849112632
-
Certolizumab pegol plus methotrexate is significantly more effective than placebo plus methotrexate in active rheumatoid arthritis: Findings of a fifty-two-week, phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group study
-
Keystone E, Heijde D, Mason D Jr, et al. Certolizumab pegol plus methotrexate is significantly more effective than placebo plus methotrexate in active rheumatoid arthritis: findings of a fifty-two-week, phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group study. Arthritis Rheum. 2008;58(11):3319-3329.
-
(2008)
Arthritis Rheum.
, vol.58
, Issue.11
, pp. 3319-3329
-
-
Keystone Jr., E.1
Heijde, D.2
Mason, D.3
-
22
-
-
67449123606
-
Efficacy and safety of certolizumab pegol monotherapy every 4 weeks in patients with rheumatoid arthritis failing previous disease-modifying antirheumatic therapy: The FAST4WARD study
-
Fleischmann R, Vencovsky J, van Vollenhoven RF, et al. Efficacy and safety of certolizumab pegol monotherapy every 4 weeks in patients with rheumatoid arthritis failing previous disease-modifying antirheumatic therapy: the FAST4WARD study. Ann Rheum Dis. 2009;68(6): 805-811.
-
(2009)
Ann Rheum Dis.
, vol.68
, Issue.6
, pp. 805-811
-
-
Fleischmann, R.1
Vencovsky, J.2
van Vollenhoven, R.F.3
-
23
-
-
67449133560
-
Golimumab, a human antibody to TNF-{alpha} given by monthly subcutaneous injections, in active rheumatoid arthritis despite methotrexate: The GO-FORWARD Study
-
Keystone EC, Genovese MC, Klareskog L, et al. Golimumab, a human antibody to TNF-{alpha} given by monthly subcutaneous injections, in active rheumatoid arthritis despite methotrexate: The GO-FORWARD Study. Ann Rheum Dis. 2009;68(6):789-786.
-
(2009)
Ann Rheum Dis.
, vol.68
, Issue.6
, pp. 786-789
-
-
Keystone, E.C.1
Genovese, M.C.2
Klareskog, L.3
-
24
-
-
42449157502
-
Golimumab in patients with active rheumatoid arthritis despite treatment with methotrexate: A randomized, double-blind, placebo-controlled, dose-ranging study
-
Apr
-
Kay J, Matteson EL, Dasgupta B, et al. Golimumab in patients with active rheumatoid arthritis despite treatment with methotrexate: a randomized, double-blind, placebo-controlled, dose-ranging study. Arthritis Rheum. 2008 Apr;58(4):964-975.
-
(2008)
Arthritis Rheum.
, vol.58
, Issue.4
, pp. 964-975
-
-
Kay, J.1
Matteson, E.L.2
Dasgupta, B.3
-
25
-
-
67449133560
-
Golimumab, a human antibody to tumour necrosis factor {alpha} given by monthly subcutaneous injections, in active rheumatoid arthritis despite methotrexate therapy: The GO-FORWARD Study
-
Keystone EC, Genovese MC, Klareskog L, et al. Golimumab, a human antibody to tumour necrosis factor {alpha} given by monthly subcutaneous injections, in active rheumatoid arthritis despite methotrexate therapy: the GO-FORWARD Study. Ann Rheum Dis. 2009;68(6): 789-796.
-
(2009)
Ann Rheum Dis.
, vol.68
, Issue.6
, pp. 789-796
-
-
Keystone, E.C.1
Genovese, M.C.2
Klareskog, L.3
-
26
-
-
34247332718
-
Incidence of tuberculosis in Korean patients with rheumatoid arthritis (RA): Effects of RA itself and of tumor necrosis factor blockers
-
Seong SS, Choi CB, Woo JH, et al. Incidence of tuberculosis in Korean patients with rheumatoid arthritis (RA): effects of RA itself and of tumor necrosis factor blockers. J Rheumatol. 2007;34(4): 706-711.
-
(2007)
J Rheumatol.
, vol.34
, Issue.4
, pp. 706-711
-
-
Seong, S.S.1
Choi, C.B.2
Woo, J.H.3
-
27
-
-
33646696885
-
Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: Systematic review and meta-analysis of rare harmful effects in randomized controlled trials
-
Bongartz T, Sutton AJ, Sweeting MJ, Buchan I, Matteson EL, Montori V. Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials. JAMA. 2006;295(19):2275-2285.
-
(2006)
JAMA.
, vol.295
, Issue.19
, pp. 2275-2285
-
-
Bongartz, T.1
Sutton, A.J.2
Sweeting, M.J.3
Buchan, I.4
Matteson, E.L.5
Montori, V.6
-
28
-
-
33644875213
-
TNF-alpha inhibitors and congestive heart failure
-
Nov-Dec
-
Behnam SM, Behnam SE, Koo JY. TNF-alpha inhibitors and congestive heart failure. Skinmed. 2005 Nov-Dec;4(6):363-368.
-
(2005)
Skinmed
, vol.4
, Issue.6
, pp. 363-368
-
-
Behnam, S.M.1
Behnam, S.E.2
Koo, J.Y.3
-
29
-
-
39749102391
-
Fungal infections complicating tumor necrosis factor alpha blockade therapy
-
Tsiodras S, Samonis G, Boumpas DT, Kontoyiannis DP. Fungal infections complicating tumor necrosis factor alpha blockade therapy. Mayo Clin Proc. 2008;83(2):181-194.
-
(2008)
Mayo Clin Proc.
, vol.83
, Issue.2
, pp. 181-194
-
-
Tsiodras, S.1
Samonis, G.2
Boumpas, D.T.3
Kontoyiannis, D.P.4
-
31
-
-
65649134752
-
A safety assessment of tumor necrosis factor antagonists during pregnancy: A review of the Food and Drug Administration database
-
Carter JD, Ladhani A, Ricca LR, Valeriano J, Vasey FB. A safety assessment of tumor necrosis factor antagonists during pregnancy: a review of the Food and Drug Administration database. J Rheumatol. 2009; 36(3):635-641.
-
(2009)
J Rheumatol.
, vol.36
, Issue.3
, pp. 635-641
-
-
Carter, J.D.1
Ladhani, A.2
Ricca, L.R.3
Valeriano, J.4
Vasey, F.B.5
-
35
-
-
56349156989
-
Autoimmune diseases induced by TNF-targeted therapies
-
Ramos-Casals M, Brito-Zeron P, Soto MJ, Cuadrado MJ, Khamashta MA. Autoimmune diseases induced by TNF-targeted therapies. Best Pract Res Clin Rheumatol. 2008;22(5):847-861.
-
(2008)
Best Pract Res Clin Rheumatol.
, vol.22
, Issue.5
, pp. 847-861
-
-
Ramos-Casals, M.1
Brito-Zeron, P.2
Soto, M.J.3
Cuadrado, M.J.4
Khamashta, M.A.5
-
36
-
-
34447345091
-
Infliximab treatmentinduced formation of autoantibodies is common in Behcet's disease
-
Elezoglou A, Kafasi N, Kaklamanis PH, et al. Infliximab treatmentinduced formation of autoantibodies is common in Behcet's disease. Clin Exp Rheumatol. 2007;25(4 Suppl 45):S65-S69.
-
(2007)
Clin Exp Rheumatol.
, vol.25
, Issue.4 SUPPL. 45
-
-
Elezoglou, A.1
Kafasi, N.2
Kaklamanis, P.H.3
-
37
-
-
65349097943
-
Is the development of drug-related lupus a contraindication for switching from one TNF alpha inhibitor to another?
-
Kocharla L, Mongey AB. Is the development of drug-related lupus a contraindication for switching from one TNF alpha inhibitor to another? Lupus. 2009;18(2):169-171.
-
(2009)
Lupus.
, vol.18
, Issue.2
, pp. 169-171
-
-
Kocharla, L.1
Mongey, A.B.2
-
38
-
-
22244478648
-
Infliximab, but not etanercept, induces IgM antidouble-stranded DNA autoantibodies as main antinuclear reactivity: Biologic and clinical implications in autoimmune arthritis
-
De Rycke L, Baeten D, Kruithof E, Van den Bosch F, Veys EM, De Keyser F. Infliximab, but not etanercept, induces IgM antidouble-stranded DNA autoantibodies as main antinuclear reactivity: biologic and clinical implications in autoimmune arthritis. Arthritis Rheum. 2005;52(7):2192-2201.
-
(2005)
Arthritis Rheum.
, vol.52
, Issue.7
, pp. 2192-2201
-
-
De Rycke, L.1
Baeten, D.2
Kruithof, E.3
van den Bosch, F.4
Veys, E.M.5
De Keyser, F.6
-
39
-
-
38549176118
-
Tumor necrosis factor antagonist mechanisms of action: A comprehensive review
-
Tracey D, Klareskog L, Sasso EH, Salfeld JG, Tak PP. Tumor necrosis factor antagonist mechanisms of action: a comprehensive review. Pharmacol Ther. 2008;117(2):244-279.
-
(2008)
Pharmacol Ther.
, vol.117
, Issue.2
, pp. 244-279
-
-
Tracey, D.1
Klareskog, L.2
Sasso, E.H.3
Salfeld, J.G.4
Tak, P.P.5
-
40
-
-
33846239331
-
Outcomes after switching from one anti-tumor necrosis factor alpha agent to a second anti-tumor necrosis factor alpha agent in patients with rheumatoid arthritis: Results from a large UK national cohort study
-
Hyrich KL, Lunt M, Watson KD, Symmons DP, Silman AJ. Outcomes after switching from one anti-tumor necrosis factor alpha agent to a second anti-tumor necrosis factor alpha agent in patients with rheumatoid arthritis: results from a large UK national cohort study. Arthritis Rheum. 2007;56(1):13-20.
-
(2007)
Arthritis Rheum.
, vol.56
, Issue.1
, pp. 13-20
-
-
Hyrich, K.L.1
Lunt, M.2
Watson, K.D.3
Symmons, D.P.4
Silman, A.J.5
-
41
-
-
50849135903
-
Adjunctive anakinra in patients with active rheumatoid arthritis despite methotrexate, or leflunomide, or cyclosporin-A monotherapy: A 48-week, comparative, prospective study
-
Karanikolas G, Charalambopoulos D, Vaiopoulos G, et al. Adjunctive anakinra in patients with active rheumatoid arthritis despite methotrexate, or leflunomide, or cyclosporin-A monotherapy: a 48-week, comparative, prospective study. Rheumatology (Oxford). 2008;47(9):1384-1388.
-
(2008)
Rheumatology (Oxford).
, vol.47
, Issue.9
, pp. 1384-1388
-
-
Karanikolas, G.1
Charalambopoulos, D.2
Vaiopoulos, G.3
-
42
-
-
67149130597
-
Anakinra for Rheumatoid Arthritis: A Systematic Review
-
Mertens M, Singh JA. Anakinra for Rheumatoid Arthritis: A Systematic Review. J Rheumatol. 2009.
-
(2009)
J Rheumatol.
-
-
Mertens, M.1
Singh, J.A.2
-
43
-
-
0035022796
-
Anti-interleukin-1 therapy in rheumatic diseases
-
Dayer JM, Feige U, Edwards CK 3rd, Burger D. Anti-interleukin-1 therapy in rheumatic diseases. Curr Opin Rheumatol. 2001;13(3): 170-176.
-
(2001)
Curr Opin Rheumatol.
, vol.13
, Issue.3
, pp. 170-176
-
-
Dayer, J.M.1
Feige, U.2
Edwards III, C.K.3
Burger, D.4
-
44
-
-
0036400340
-
Anakinra as a new therapeutic option in rheumatoid arthritis: Clinical results and perspectives
-
Bresnihan B. Anakinra as a new therapeutic option in rheumatoid arthritis: clinical results and perspectives. Clin Exp Rheumatol. 2002; 20(5 Suppl 27):S32-S34.
-
(2002)
Clin Exp Rheumatol.
, vol.20
, Issue.5 SUPPL. 27
-
-
Bresnihan, B.1
-
45
-
-
18244420184
-
Addressing the safety of anakinra in patients with rheumatoid arthritis
-
Fleischmann RM. Addressing the safety of anakinra in patients with rheumatoid arthritis. Rheumatology (Oxford). 2003;42 Suppl 2: ii29-ii35.
-
(2003)
Rheumatology (Oxford)
, vol.42
, Issue.SUPPL. 2
-
-
Fleischmann, R.M.1
-
46
-
-
42549120251
-
Autoinflammatory syndromes and infections: Pathogenetic and clinical implications
-
Efthimiou P, Flavell RA, Furlan A, et al. Autoinflammatory syndromes and infections: pathogenetic and clinical implications. Clin Exp Rheumatol. 2008;26(1 Suppl 48):S53-S61.
-
(2008)
Clin Exp Rheumatol.
, vol.26
, Issue.1 SUPPL. 48
-
-
Efthimiou, P.1
Flavell, R.A.2
Furlan, A.3
-
47
-
-
53649101010
-
Emerging therapeutics for rheumatoid arthritis
-
Bingham CO 3rd. Emerging therapeutics for rheumatoid arthritis. Bull NYU Hosp Jt Dis. 2008;66(3):210-215.
-
(2008)
Bull NYU Hosp Jt Dis.
, vol.66
, Issue.3
, pp. 210-215
-
-
Bingham III, C.O.1
-
48
-
-
33745894354
-
Regulation of pre-B cell colony-enhancing factor by STAT-3-dependent interleukin-6 transsignaling: Implications in the pathogenesis of rheumatoid arthritis
-
Nowell MA, Richards PJ, Fielding CA, et al. Regulation of pre-B cell colony-enhancing factor by STAT-3-dependent interleukin-6 transsignaling: implications in the pathogenesis of rheumatoid arthritis. Arthritis Rheum. 2006;54(7):2084-2095.
-
(2006)
Arthritis Rheum.
, vol.54
, Issue.7
, pp. 2084-2095
-
-
Nowell, M.A.1
Richards, P.J.2
Fielding, C.A.3
-
49
-
-
64949203166
-
Tocilizumab: A review of its use in the management of rheumatoid arthritis
-
Oldfield V, Dhillon S, Plosker GL. Tocilizumab: a review of its use in the management of rheumatoid arthritis. Drugs. 2009;69(5):609-632.
-
(2009)
Drugs.
, vol.69
, Issue.5
, pp. 609-632
-
-
Oldfield, V.1
Dhillon, S.2
Plosker, G.L.3
-
50
-
-
73449118587
-
Comparison of tocilizumab monotherapy versus methotrexate monotherapy in patients with moderate to severe rheumatoid arthritis: The AMBITION study
-
Jones G, Sebba A, Gu J, et al. Comparison of tocilizumab monotherapy versus methotrexate monotherapy in patients with moderate to severe rheumatoid arthritis: The AMBITION study. Ann Rheum Dis. 2009.
-
(2009)
Ann Rheum Dis.
-
-
Jones, G.1
Sebba, A.2
Gu, J.3
-
51
-
-
60149105639
-
Study of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): Significant reduction in disease activity and serum vascular endothelial growth factor by IL-6 receptor inhibition therapy
-
Nishimoto N, Miyasaka N, Yamamoto K, et al. Study of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): significant reduction in disease activity and serum vascular endothelial growth factor by IL-6 receptor inhibition therapy. Mod Rheumatol. 2009;19(1):12-19.
-
(2009)
Mod Rheumatol.
, vol.19
, Issue.1
, pp. 12-19
-
-
Nishimoto, N.1
Miyasaka, N.2
Yamamoto, K.3
-
52
-
-
33749363027
-
Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate
-
Maini RN, Taylor PC, Szechinski J, et al. Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate. Arthritis Rheum. 2006;54(9):2817-2829.
-
(2006)
Arthritis Rheum.
, vol.54
, Issue.9
, pp. 2817-2829
-
-
Maini, R.N.1
Taylor, P.C.2
Szechinski, J.3
-
53
-
-
52149099504
-
IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: Results from a 24-week multicentre randomised placebo-controlled trial
-
Emery P, Keystone E, Tony HP, et al. IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: results from a 24-week multicentre randomised placebo-controlled trial. Ann Rheum Dis. 2008;67(11):1516-1523.
-
(2008)
Ann Rheum Dis.
, vol.67
, Issue.11
, pp. 1516-1523
-
-
Emery, P.1
Keystone, E.2
Tony, H.P.3
-
54
-
-
64849093693
-
Blockade of interleukin 6 signaling induces marked neutropenia in patients with rheumatoid arthritis
-
Nakamura I, Omata Y, Naito M, Ito K. Blockade of interleukin 6 signaling induces marked neutropenia in patients with rheumatoid arthritis. J Rheumatol. 2009;36(2):459-460.
-
(2009)
J Rheumatol.
, vol.36
, Issue.2
, pp. 459-460
-
-
Nakamura, I.1
Omata, Y.2
Naito, M.3
Ito, K.4
-
55
-
-
2942537697
-
Efficacy of B-celltargeted therapy with rituximab in patients with rheumatoid arthritis
-
Edwards JC, Szczepanski L, Szechinski J, et al. Efficacy of B-celltargeted therapy with rituximab in patients with rheumatoid arthritis. N Engl J Med. 2004;350(25):2572-2581.
-
(2004)
N Engl J Med.
, vol.350
, Issue.25
, pp. 2572-2581
-
-
Edwards, J.C.1
Szczepanski, L.2
Szechinski, J.3
-
56
-
-
33746961890
-
Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: Results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks
-
Cohen SB, Emery P, Greenwald MW, et al. Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: Results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks. Arthritis Rheum. 2006;54(9):2793-2806.
-
(2006)
Arthritis Rheum.
, vol.54
, Issue.9
, pp. 2793-2806
-
-
Cohen, S.B.1
Emery, P.2
Greenwald, M.W.3
-
57
-
-
33646483031
-
The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: Results of a phase IIB randomized, double-blind, placebo-controlled, dose-ranging trial
-
May
-
Emery P, Fleischmann R, Filipowicz-Sosnowska A, et al. The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: results of a phase IIB randomized, double-blind, placebo-controlled, dose-ranging trial. Arthritis Rheum. 2006 May;54(5):1390-1400.
-
(2006)
Arthritis Rheum.
, vol.54
, Issue.5
, pp. 1390-1400
-
-
Emery, P.1
Fleischmann, R.2
Filipowicz-Sosnowska, A.3
-
58
-
-
58849088519
-
Rituximab inhibits structural joint damage in patients with rheumatoid arthritis with an inadequate response to tumour necrosis factor inhibitor therapies
-
Keystone E, Emery P, Peterfy CG, et al. Rituximab inhibits structural joint damage in patients with rheumatoid arthritis with an inadequate response to tumour necrosis factor inhibitor therapies. Ann Rheum Dis. 2009;68(2):216-221.
-
(2009)
Ann Rheum Dis.
, vol.68
, Issue.2
, pp. 216-221
-
-
Keystone, E.1
Emery, P.2
Peterfy, C.G.3
-
59
-
-
34248545097
-
B cell depletion may be more effective than switching to an alternative anti-tumor necrosis factor agent in rheumatoid arthritis patients with inadequate response to anti-tumor necrosis factor agents
-
Finckh A, Ciurea A, Brulhart L, et al. B cell depletion may be more effective than switching to an alternative anti-tumor necrosis factor agent in rheumatoid arthritis patients with inadequate response to anti-tumor necrosis factor agents. Arthritis Rheum. 2007;56(5):1417-1423.
-
(2007)
Arthritis Rheum.
, vol.56
, Issue.5
, pp. 1417-1423
-
-
Finckh, A.1
Ciurea, A.2
Brulhart, L.3
-
60
-
-
56349103348
-
Progressive multifocal leukoencephalopathy in patients with rheumatic diseases: Are patients with systemic lupus erythematosus at particular risk?
-
Molloy ES, Calabrese LH. Progressive multifocal leukoencephalopathy in patients with rheumatic diseases: are patients with systemic lupus erythematosus at particular risk? Autoimmun Rev. 2008;8(2):144-146.
-
(2008)
Autoimmun Rev.
, vol.8
, Issue.2
, pp. 144-146
-
-
Molloy, E.S.1
Calabrese, L.H.2
-
61
-
-
38049000341
-
The emergence of progressive multifocal leukoencephalopathy (PML) in rheumatic diseases
-
Boren EJ, Cheema GS, Naguwa SM, Ansari AA, Gershwin ME. The emergence of progressive multifocal leukoencephalopathy (PML) in rheumatic diseases. J Autoimmun. 2008;30(1-2):90-98.
-
(2008)
J Autoimmun.
, vol.30
, Issue.1-2
, pp. 90-98
-
-
Boren, E.J.1
Cheema, G.S.2
Naguwa, S.M.3
Ansari, A.A.4
Gershwin, M.E.5
-
62
-
-
51849148443
-
Ocrelizumab, a humanized anti-CD20 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I/II randomized, blinded, placebo-controlled, dose-ranging study
-
Genovese MC, Kaine JL, Lowenstein MB, et al. Ocrelizumab, a humanized anti-CD20 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I/II randomized, blinded, placebo-controlled, dose-ranging study. Arthritis Rheum. 2008;58(9): 2652-2661.
-
(2008)
Arthritis Rheum.
, vol.58
, Issue.9
, pp. 2652-2661
-
-
Genovese, M.C.1
Kaine, J.L.2
Lowenstein, M.B.3
-
63
-
-
54049145062
-
Improving patient outlook in rheumatoid arthritis: Experience with abatacept
-
Coughlin M. Improving patient outlook in rheumatoid arthritis: experience with abatacept. J Am Acad Nurse Pract. 2008;20(10): 486-495.
-
(2008)
J Am Acad Nurse Pract.
, vol.20
, Issue.10
, pp. 486-495
-
-
Coughlin, M.1
-
64
-
-
33749365296
-
Safety of the selective costimulation modulator abatacept in rheumatoid arthritis patients receiving background biologic and nonbiologic disease-modifying antirheumatic drugs: A one-year randomized, placebo-controlled study
-
Weinblatt M, Combe B, Covucci A, Aranda R, Becker JC, Keystone E. Safety of the selective costimulation modulator abatacept in rheumatoid arthritis patients receiving background biologic and nonbiologic disease-modifying antirheumatic drugs: A one-year randomized, placebo-controlled study. Arthritis Rheum. 2006;54(9): 2807-2816.
-
(2006)
Arthritis Rheum.
, vol.54
, Issue.9
, pp. 2807-2816
-
-
Weinblatt, M.1
Combe, B.2
Covucci, A.3
Aranda, R.4
Becker, J.C.5
Keystone, E.6
-
65
-
-
33745291091
-
Effects of abatacept in patients with methotrexate-resistant active rheumatoid arthritis: A randomized trial
-
Jun 20
-
Kremer JM, Genant HK, Moreland LW, et al. Effects of abatacept in patients with methotrexate-resistant active rheumatoid arthritis: a randomized trial. Ann Intern Med. 2006 Jun 20;144(12):865-876.
-
(2006)
Ann Intern Med.
, vol.144
, Issue.12
, pp. 865-876
-
-
Kremer, J.M.1
Genant, H.K.2
Moreland, L.W.3
-
66
-
-
24944498854
-
Abatacept for rheumatoid arthritis refractory to tumor necrosis factor alpha inhibition
-
Genovese MC, Becker JC, Schiff M, et al. Abatacept for rheumatoid arthritis refractory to tumor necrosis factor alpha inhibition. N Engl J Med. 2005;353(11):1114-1123.
-
(2005)
N Engl J Med.
, vol.353
, Issue.11
, pp. 1114-1123
-
-
Genovese, M.C.1
Becker, J.C.2
Schiff, M.3
-
67
-
-
47949106400
-
Efficacy and safety of abatacept or infliximab vs placebo in ATTEST: A phase III, multicentre, randomised, double-blind, placebo-controlled study in patients with rheumatoid arthritis and an inadequate response to methotrexate
-
Schiff M, Keiserman M, Codding C, et al. Efficacy and safety of abatacept or infliximab vs placebo in ATTEST: a phase III, multicentre, randomised, double-blind, placebo-controlled study in patients with rheumatoid arthritis and an inadequate response to methotrexate. Ann Rheum Dis. 2008;67(8):1096-1103.
-
(2008)
Ann Rheum Dis.
, vol.67
, Issue.8
, pp. 1096-1103
-
-
Schiff, M.1
Keiserman, M.2
Codding, C.3
-
68
-
-
42449098374
-
Results of a two-year followup study of patients with rheumatoid arthritis who received a combination of abatacept and methotrexate
-
Kremer JM, Genant HK, Moreland LW, et al. Results of a two-year followup study of patients with rheumatoid arthritis who received a combination of abatacept and methotrexate. Arthritis Rheum. 2008; 58(4):953-963.
-
(2008)
Arthritis Rheum.
, vol.58
, Issue.4
, pp. 953-963
-
-
Kremer, J.M.1
Genant, H.K.2
Moreland, L.W.3
-
69
-
-
33846853779
-
Selective costimulation modulation using abatacept in patients with active rheumatoid arthritis while receiving etanercept: A randomised clinical trial
-
Weinblatt M, Schiff M, Goldman A, et al. Selective costimulation modulation using abatacept in patients with active rheumatoid arthritis while receiving etanercept: a randomised clinical trial. Ann Rheum Dis. 2007;66(2):228-234.
-
(2007)
Ann Rheum Dis.
, vol.66
, Issue.2
, pp. 228-234
-
-
Weinblatt, M.1
Schiff, M.2
Goldman, A.3
-
70
-
-
65349176911
-
Clinical efficacy and safety of abatacept in methotrexate-naive patients with early rheumatoid arthritis and poor prognostic factors
-
Jan 9. [Epub ahead of print]
-
Westhovens R, Robles M, Ximenes AC, et al. Clinical efficacy and safety of abatacept in methotrexate-naive patients with early rheumatoid arthritis and poor prognostic factors. Ann Rheum Dis. 2009 Jan 9. [Epub ahead of print].
-
(2009)
Ann Rheum Dis.
-
-
Westhovens, R.1
Robles, M.2
Ximenes, A.C.3
-
71
-
-
66149093043
-
Safety and efficacy of the selective costimulation modulator abatacept in patients with rheumatoid arthritis receiving background methotrexate: A 5-year extended phase IIB study
-
Apr
-
Westhovens R, Kremer JM, Moreland LW, et al. Safety and efficacy of the selective costimulation modulator abatacept in patients with rheumatoid arthritis receiving background methotrexate: a 5-year extended phase IIB study. J Rheumatol. 2009 Apr;36(4):736-742.
-
(2009)
J Rheumatol.
, vol.36
, Issue.4
, pp. 736-742
-
-
Westhovens, R.1
Kremer, J.M.2
Moreland, L.W.3
-
72
-
-
67449159941
-
Malignancies in the rheumatoid arthritis abatacept clinical development program: An epidemiological assessment
-
Simon TA, Smitten AL, Franklin J, et al. Malignancies in the rheumatoid arthritis abatacept clinical development program: An epidemiological assessment. Ann Rheum Dis. 2008.
-
(2008)
Ann Rheum Dis.
-
-
Simon, T.A.1
Smitten, A.L.2
Franklin, J.3
-
73
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
Bettelli E, Carrier Y, Gao W, et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature. 2006;441(7090):235-238.
-
(2006)
Nature.
, vol.441
, Issue.7090
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
-
74
-
-
26044455144
-
Expression of IL-17 homologs and their receptors in the synovial cells of rheumatoid arthritis patients
-
Hwang SY, Kim HY. Expression of IL-17 homologs and their receptors in the synovial cells of rheumatoid arthritis patients. Mol Cells. 2005; 19(2):180-184.
-
(2005)
Mol Cells.
, vol.19
, Issue.2
, pp. 180-184
-
-
Hwang, S.Y.1
Kim, H.Y.2
-
75
-
-
0035990279
-
Interleukin 17 (IL-17) induces collagenase-3 production in human osteoarthritic chondrocytes via AP-1 dependent activation: Differential activation of AP-1 members by IL-17 and IL-1beta
-
Benderdour M, Tardif G, Pelletier JP, et al. Interleukin 17 (IL-17) induces collagenase-3 production in human osteoarthritic chondrocytes via AP-1 dependent activation: differential activation of AP-1 members by IL-17 and IL-1beta. J Rheumatol. 2002;29(6):1262-1272.
-
(2002)
J Rheumatol.
, vol.29
, Issue.6
, pp. 1262-1272
-
-
Benderdour, M.1
Tardif, G.2
Pelletier, J.P.3
-
76
-
-
0035997484
-
Interleukin 17 induces cartilage collagen breakdown: Novel synergistic effects in combination with proinflammatory cytokines
-
Koshy PJ, Henderson N, Logan C, Life PF, Cawston TE, Rowan AD. Interleukin 17 induces cartilage collagen breakdown: novel synergistic effects in combination with proinflammatory cytokines. Ann Rheum Dis. 2002;61(8):704-713.
-
(2002)
Ann Rheum Dis.
, vol.61
, Issue.8
, pp. 704-713
-
-
Koshy, P.J.1
Henderson, N.2
Logan, C.3
Life, P.F.4
Cawston, T.E.5
Rowan, A.D.6
-
77
-
-
33750351338
-
Potential new targets in arthritis therapy: Interleukin (IL)-17 and its relation to tumour necrosis factor and IL-1 in experimental arthritis
-
Koenders MI, Joosten LA, van den Berg WB. Potential new targets in arthritis therapy: interleukin (IL)-17 and its relation to tumour necrosis factor and IL-1 in experimental arthritis. Ann Rheum Dis. 2006;65 Suppl 3: iii29-iii33.
-
(2006)
Ann Rheum Dis.
, vol.65
, Issue.SUPPL. 3
-
-
Koenders, M.I.1
Joosten, L.A.2
van den Berg, W.B.3
-
78
-
-
0037415599
-
G-CSF-stimulated neutrophils are a prominent source of functional BLyS
-
Scapini P, Nardelli B, Nadali G, et al. G-CSF-stimulated neutrophils are a prominent source of functional BLyS. J Exp Med. 2003;197(3):297-302.
-
(2003)
J Exp Med.
, vol.197
, Issue.3
, pp. 297-302
-
-
Scapini, P.1
Nardelli, B.2
Nadali, G.3
-
79
-
-
19944428744
-
Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: Implications for inflammatory diseases
-
Scapini P, Carletto A, Nardelli B, et al. Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: implications for inflammatory diseases. Blood. 2005;105(2):830-837.
-
(2005)
Blood.
, vol.105
, Issue.2
, pp. 830-837
-
-
Scapini, P.1
Carletto, A.2
Nardelli, B.3
-
80
-
-
0037386743
-
Local production of B lymphocyte stimulator protein and APRIL in arthritic joints of patients with inflammatory arthritis
-
Tan SM, Xu D, Roschke V, et al. Local production of B lymphocyte stimulator protein and APRIL in arthritic joints of patients with inflammatory arthritis. Arthritis Rheum. 2003;48(4):982-992.
-
(2003)
Arthritis Rheum.
, vol.48
, Issue.4
, pp. 982-992
-
-
Tan, S.M.1
Xu, D.2
Roschke, V.3
-
81
-
-
0034972257
-
Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases
-
Cheema GS, Roschke V, Hilbert DM, Stohl W. Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases. Arthritis Rheum. 2001;44(6):1313-1319.
-
(2001)
Arthritis Rheum.
, vol.44
, Issue.6
, pp. 1313-1319
-
-
Cheema, G.S.1
Roschke, V.2
Hilbert, D.M.3
Stohl, W.4
-
82
-
-
58549086734
-
The BLyS family: Toward a molecular understanding of B cell homeostasis
-
Treml JF, Hao Y, Stadanlick JE, Cancro MP. The BLyS family: toward a molecular understanding of B cell homeostasis. Cell Biochem Biophys. 2009;53(1):1-16.
-
(2009)
Cell Biochem Biophys.
, vol.53
, Issue.1
, pp. 1-16
-
-
Treml, J.F.1
Hao, Y.2
Stadanlick, J.E.3
Cancro, M.P.4
-
83
-
-
67449162094
-
New tumour necrosis factor inhibitors for rheumatoid arthritis: Are there benefits from extending choice?
-
Scott DL, Cope A. New tumour necrosis factor inhibitors for rheumatoid arthritis: are there benefits from extending choice? Ann Rheum Dis. 2009;68(6):767-769.
-
(2009)
Ann Rheum Dis.
, vol.68
, Issue.6
, pp. 767-769
-
-
Scott, D.L.1
Cope, A.2
|