Evaluation of the cytotoxicity of a two photon absorbing fluorescence compound on human HepG2 cells and its application to tracking human hepatic cancer cells in mice

Biotechnic and Histochemistry

Volumn 85, Issue 2, 2010, Pages 107-113

  Du, X M ^a,b   Yan, Y ^c   Bai, Z L ^a   Zhang, J P ^a   Wang, Z ^a   Liu, L L ^a   Feng, L J ^a  

^a SHANDONG UNIVERSITY   (China)

^b JINAN MILITARY GENERAL HOSPITAL   (China)

^c Shandong University   (China)

Author keywords

Cytotoxic T lymphocytes; Cytotoxicity; Fluorescence imaging; Hepatic cancer; Two photon absorption

Indexed keywords

4 (N 2 HYDROXYETHYL N ETHYLAMINO) 4' (DIMETHYL AMINO)STILBENE; 4-(N-2-HYDROXYETHYL-N-ETHYLAMINO)-4'-(DIMETHYL AMINO)STILBENE; CYTOTOXIN; DIAGNOSTIC AGENT; FLUORESCENT DYE; STILBENE DERIVATIVE;

ANIMAL; ANIMAL MODEL; ARTICLE; CELL DEATH; CELL STRAIN HEPG2; DIAGNOSTIC IMAGING; DRUG EFFECT; FLOW CYTOMETRY; HUMAN; LIVER TUMOR; METHODOLOGY; MOUSE; PATHOLOGY; DIAGNOSTIC USE; DRUG EFFECTS; HEPG2 CELL LINE; LIVER NEOPLASMS, EXPERIMENTAL; PROCEDURES;

ANIMALS; CELL DEATH; CYTOTOXINS; DIAGNOSTIC IMAGING; FLOW CYTOMETRY; FLUORESCENT DYES; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS, EXPERIMENTAL; MICE; MODELS, ANIMAL; STILBENES;

MUS;

EID: 77949452105     PISSN: 10520295     EISSN: 14737760     Source Type: Journal    
DOI: 10.3109/10520290903149588     Document Type: Article

References (14)

1. Carreon JR, Stewart KM, Mahon KP, Jr Shin S, Kelley SO (2007) Cyanine dye conjugates as probes for live cell imaging. Bioorg. Med. Chem. Lett. 17: 5182-5185.
2. Davoren M, Herzog E, Casey A, Cottineau B, Chambers G, Byrne H (2007) In vitro toxicity evaluation of single walled carbon nanotubes on human A549 lung cells. Toxicol. in Vitro. 21: 438-448.
3. Gao X, Cui Y, Levenson RM, Chung LW, Nie S (2004) In vivo cancer targeting and imaging with semiconductor quantum dots. Nat. Biotechnol. 22: 959-960.
4. Kovar JL, Simpson MA, Schutz-Geschwender A, Olive DM (2007) A systematic approach to the development of fl uorescent contrast agents for optical imaging of mouse cancer models. Anal. Biochem. 367: 1-12.
5. Lecoeur H, Fevrier M, Garcia S, Riviere Y, Gougeon ML (2001) A novel fl ow cytometric assay for quantitation and multiparametric characterization of cell-mediated cytotoxicity. J. Immunol. Methods 253: 177-187.
6. Liu L, Packard BZ, Brown MJ, Komoriya A, Feinberg MB (2004) Methods in Molecular Biology: Flow Cytometry Protocols. Humana Press, Totowa, NJ. pp. 125-139.
7. Rao J, Dragulescu-Andrasi A, Yao H (2007) Fluorescence imaging in vivo: recent advances. Curr. Opin. Biotechnol. 18: 17-25.
8. Riccardi C, Nicoletti I (2006) Analysis of apoptosis by propidium iodide staining and fl ow cytometry. Nat. Protoc. 1: 1458-1461.
9. Sheehy ME, McDermott AB, Furlan SN, Klenerman P, Nixon DF (2001) A novel technique for the fl uorometric assessment of T lymphocyte antigen specifi c lysis. J. Immunol. Methods 249: 99-110.
10. Terai T, Nagano T (2008) Fluorescent probes for bioimaging applications. Curr. Opin. Chem. Biol. 12: 515-521.
11. Voura EB, Jaiswal JK, Mattoussi H, Simon SM (2004) Tracking metastatic tumor cell extravasation with quantum dot nanocrystals and fl uorescence emission-scanning microscopy. Nat. Med. 10: 993-998.
12. Wang M, Bai F, Pries M, Buus S, Prause JU, Nissen MH (2006) Identifi cation of MHC class I H-2 Kb/Db-restricted immunogenic peptides derived from retinal proteins. Invest. Ophthal. Vis. Sci. 47: 3939-3945.
13. Wang Z, Bai Z, Zhang H, Huan T, Li J, Du X, Zhang J (2009) Growth potential of human hepatocarcinoma cells in the liver of neonatal immunocompetent mice and its relation to immunological tolerance. Prog. Nat. Sci. 19: 705-712.
14. Yan Y (2003) Synthesis and nonlinear optical properties of new symmetrically substituted stilbenes. J. Solid State Chem. 172: 364-369.