-
1
-
-
0014691619
-
Platinum compounds: A new class of potent antitumour agents
-
Rosenberg B, VanCamp L, Trosko JE, Mansour VH. Platinum compounds: a new class of potent antitumour agents. Nature. 1969;26(222):385-386.
-
(1969)
Nature
, vol.26
, Issue.222
, pp. 385-386
-
-
Rosenberg, B.1
VanCamp, L.2
Trosko, J.E.3
Mansour, V.H.4
-
2
-
-
0025020085
-
Phase I study of oxaliplatin in patients with advanced cancer
-
Extra JM, Espie M, Calvo F, Ferme C, Mignot L, Marty M. Phase I study of oxaliplatin in patients with advanced cancer. Cancer Chemother Pharmacol. 1990;25(4):299-303.
-
(1990)
Cancer Chemother Pharmacol
, vol.25
, Issue.4
, pp. 299-303
-
-
Extra, J.M.1
Espie, M.2
Calvo, F.3
Ferme, C.4
Mignot, L.5
Marty, M.6
-
3
-
-
0004700371
-
Oxaliplatin as single agent in previously untreated colorectal carcinoma patients: A phase II multicentric study
-
Diaz-Rubio E, Sastre J, Zaniboni A, et al. Oxaliplatin as single agent in previously untreated colorectal carcinoma patients: A phase II multicentric study. Ann Oncol. 1998;9(1):105-118.
-
(1998)
Ann Oncol
, vol.9
, Issue.1
, pp. 105-118
-
-
Diaz-Rubio, E.1
Sastre, J.2
Zaniboni, A.3
-
4
-
-
0012797224
-
Two consecutive phase II studies of oxaliplatin (L-OHP) for treatment of patients with advanced colorectal carcinoma who were resistant to previous treatment with fluoropyrimidines
-
Machover D, Diaz-Rubio E, de Gramont A, et al. Two consecutive phase II studies of oxaliplatin (L-OHP) for treatment of patients with advanced colorectal carcinoma who were resistant to previous treatment with fluoropyrimidines. Ann Oncol. 1996;7(1):95-98.
-
(1996)
Ann Oncol
, vol.7
, Issue.1
, pp. 95-98
-
-
Machover, D.1
Diaz-Rubio, E.2
de Gramont, A.3
-
5
-
-
0027310715
-
Oxaliplatin activity against metastatic colorectal cancer. A phase II study of 5-day continuous venous infusion at circadian rhythm modulated rate
-
Lévi F, Perpoint B, GarufiC, et al. Oxaliplatin activity against metastatic colorectal cancer. A phase II study of 5-day continuous venous infusion at circadian rhythm modulated rate. Eur J Cancer. 1993;29(9):1280-1284.
-
(1993)
Eur J Cancer
, vol.29
, Issue.9
, pp. 1280-1284
-
-
Lévi, F.1
Perpoint, B.2
GarufiC3
-
6
-
-
0030888321
-
Oxaliplatin with high-dose leucovorin and 5-fluorouracil 48-hour continuous infusion in pretreated metastatic colorectal cancer
-
De Gramont A, Vignoud J, Tournigand C, et al. Oxaliplatin with high-dose leucovorin and 5-fluorouracil 48-hour continuous infusion in pretreated metastatic colorectal cancer. Eur J Cancer. 1997;33(2):214-219.
-
(1997)
Eur J Cancer
, vol.33
, Issue.2
, pp. 214-219
-
-
De Gramont, A.1
Vignoud, J.2
Tournigand, C.3
-
7
-
-
0031774842
-
Bimonthly high dose leucovorin, 5-fluorouracil infusion and oxaliplatin (FOLFOX3) for metastatic colorectal cancer resistant to the same leucovorin and 5-fluorouracil regimen
-
André T, Louvet C, Raymond E, Tournigand C, de Gramont A. Bimonthly high dose leucovorin, 5-fluorouracil infusion and oxaliplatin (FOLFOX3) for metastatic colorectal cancer resistant to the same leucovorin and 5-fluorouracil regimen. Ann Oncol. 1998;9(11): 1251-1253.
-
(1998)
Ann Oncol
, vol.9
, Issue.11
, pp. 1251-1253
-
-
André, T.1
Louvet, C.2
Raymond, E.3
Tournigand, C.4
de Gramont, A.5
-
8
-
-
0033874892
-
Leucovorin and Fluorouracil With or Without Oxaliplatin as First-Line Treatment in Advanced Colorectal Cancer
-
De Gramont A, Figer A, Seymour M, et al. Leucovorin and Fluorouracil With or Without Oxaliplatin as First-Line Treatment in Advanced Colorectal Cancer. J Clin Oncol. 2000;18(16):2938-2847.
-
(2000)
J Clin Oncol
, vol.18
, Issue.16
, pp. 2938-2847
-
-
De Gramont, A.1
Figer, A.2
Seymour, M.3
-
9
-
-
60649088752
-
Two different first-line 5-fluorouracil regimens with or without oxaliplatin in patients with metastatic colorectal cancer
-
Epub Oct 14. doi:10.1093/annonc/ mdn638
-
Cunningham D, Sirohi B, Pluzanska A, et al. Two different first-line 5-fluorouracil regimens with or without oxaliplatin in patients with metastatic colorectal cancer. Ann Oncol. Epub 2008 Oct 14. doi:10.1093/annonc/ mdn638.
-
(2008)
Ann Oncol
-
-
Cunningham, D.1
Sirohi, B.2
Pluzanska, A.3
-
10
-
-
1842569206
-
A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer
-
Goldberg RM, Sargent DJ, Morton RF, et al. A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer. J Clin Oncol. 2004;22(1):23-30.
-
(2004)
J Clin Oncol
, vol.22
, Issue.1
, pp. 23-30
-
-
Goldberg, R.M.1
Sargent, D.J.2
Morton, R.F.3
-
11
-
-
33746805967
-
Randomized controlled trial of reduced-dose bolus fluorouracil plus leucovorin and irinotecan or infused fluorouracil plus leucovorin and oxaliplatin in patients with previously untreated metastatic colorectal cancer: A North American Intergroup Trial
-
Goldberg RM, Sargent DJ, Morton RF, et al. Randomized controlled trial of reduced-dose bolus fluorouracil plus leucovorin and irinotecan or infused fluorouracil plus leucovorin and oxaliplatin in patients with previously untreated metastatic colorectal cancer: A North American Intergroup Trial. J Clin Oncol. 2006;24(21):3347-3353.
-
(2006)
J Clin Oncol
, vol.24
, Issue.21
, pp. 3347-3353
-
-
Goldberg, R.M.1
Sargent, D.J.2
Morton, R.F.3
-
12
-
-
1342290189
-
FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: A randomized GERCOR Study
-
Tournigand C, André T, Achille E, et al. FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: A randomized GERCOR Study. J Clin Oncol. 2004;22(2):229-237.
-
(2004)
J Clin Oncol
, vol.22
, Issue.2
, pp. 229-237
-
-
Tournigand, C.1
André, T.2
Achille, E.3
-
13
-
-
24644457747
-
Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: A multicenter Study of the Gruppo Oncologico Dell'Italia Meridionale
-
Colucci G, Gebbia V, Paoletti G, et al. Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: A multicenter Study of the Gruppo Oncologico Dell'Italia Meridionale. J Clin Oncol. 2005;23(22):4866-4875.
-
(2005)
J Clin Oncol
, vol.23
, Issue.22
, pp. 4866-4875
-
-
Colucci, G.1
Gebbia, V.2
Paoletti, G.3
-
14
-
-
21344459245
-
Oxaliplatin plus high dose folinic acid and 5-fluoruracil i.v. bolus (OXAFAFU) versus irinotecan plus high dose folinic acid and 5-fluoruracil i.v. bolus (IRIFAFU) in patients with metastatic colorectal carcinoma: A Southern Italy Cooperative Oncology Group phase III trial
-
Comella P, Massidda B, Filippelli G, et al. Oxaliplatin plus high dose folinic acid and 5-fluoruracil i.v. bolus (OXAFAFU) versus irinotecan plus high dose folinic acid and 5-fluoruracil i.v. bolus (IRIFAFU) in patients with metastatic colorectal carcinoma: A Southern Italy Cooperative Oncology Group phase III trial. Ann Oncol. 2005;16(6):878-886.
-
(2005)
Ann Oncol
, vol.16
, Issue.6
, pp. 878-886
-
-
Comella, P.1
Massidda, B.2
Filippelli, G.3
-
15
-
-
21344448162
-
Irinotecan or oxaliplatin combined with leucovorin and 5-fluorouracil as first-line treatment in advanced colorectal cancer: A multicenter, randomized, phase II study
-
Kalofonos HP, Aravantinos G, Kosmidis P, et al. Irinotecan or oxaliplatin combined with leucovorin and 5-fluorouracil as first-line treatment in advanced colorectal cancer: a multicenter, randomized, phase II study. Ann Oncol. 2005;16(6):869-877.
-
(2005)
Ann Oncol
, vol.16
, Issue.6
, pp. 869-877
-
-
Kalofonos, H.P.1
Aravantinos, G.2
Kosmidis, P.3
-
16
-
-
0037531121
-
Superiority of oxaliplatin and fluorouracil-leucovorin compared with either therapy alone in patients with progressive colorectal cancer after irinotecan and fluorouracil-leucovorin: Interim results of a phase III trial
-
Rothenberg ML, Oza AM, Bigelow RH, et al. Superiority of oxaliplatin and fluorouracil-leucovorin compared with either therapy alone in patients with progressive colorectal cancer after irinotecan and fluorouracil-leucovorin: Interim results of a phase III trial. J Clin Oncol. 2003;21(11):2059- 2069.
-
(2003)
J Clin Oncol
, vol.21
, Issue.11
, pp. 2059-2069
-
-
Rothenberg, M.L.1
Oza, A.M.2
Bigelow, R.H.3
-
17
-
-
0035871538
-
Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients metastatic colorectal cancer: Results of a randomized phase III study
-
Hoff PM, Ansari R, Batist G, et al. Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients metastatic colorectal cancer: results of a randomized phase III study. J Clin Oncol. 2001;19(8):2282-2292.
-
(2001)
J Clin Oncol
, vol.19
, Issue.8
, pp. 2282-2292
-
-
Hoff, P.M.1
Ansari, R.2
Batist, G.3
-
18
-
-
0035503151
-
Oral capecitabine compared with fluorouracil plus leucovorin in patients with metastatic colorectal cancer: Results of a large phase III study
-
Van Cutsem E, Twelves C, Cassidy J, et al. Oral capecitabine compared with fluorouracil plus leucovorin in patients with metastatic colorectal cancer: results of a large phase III study. J Clin Oncol. 2001;19(21):4097-4106.
-
(2001)
J Clin Oncol
, vol.19
, Issue.21
, pp. 4097-4106
-
-
Van Cutsem, E.1
Twelves, C.2
Cassidy, J.3
-
19
-
-
0036176033
-
Capecitabine as first-line treatment in colorectal cancer: Pooled data from two large, phase III trials. Capecitabine Colorectal Cancer Group
-
Twelves C. Capecitabine as first-line treatment in colorectal cancer: pooled data from two large, phase III trials. Capecitabine Colorectal Cancer Group. Eur J Cancer. 2002;38(Suppl 2):15-20.
-
(2002)
Eur J Cancer
, vol.38
, Issue.SUPPL. 2
, pp. 15-20
-
-
Twelves, C.1
-
20
-
-
2942638081
-
XELOX (capecitabine plus oxaliplatin): Active first-line therapy for patients with metastatic colorectal cancer
-
Cassidy J, Tabernero J, Twelves CJ, et al. XELOX (capecitabine plus oxaliplatin): Active first-line therapy for patients with metastatic colorectal cancer. J Clin Oncol. 2004;22(11):2084-2089.
-
(2004)
J Clin Oncol
, vol.22
, Issue.11
, pp. 2084-2089
-
-
Cassidy, J.1
Tabernero, J.2
Twelves, C.J.3
-
21
-
-
33645731984
-
XELOX (capecitabine plus oxaliplatin) as first-line treatment for elderly patients over 70 years of age with advanced colorectal cancer
-
Feliu J, Salud A, Escudero P, et al: XELOX (capecitabine plus oxaliplatin) as first-line treatment for elderly patients over 70 years of age with advanced colorectal cancer. Br J Cancer. 2006;94(7):969-975.
-
(2006)
Br J Cancer
, vol.94
, Issue.7
, pp. 969-975
-
-
Feliu, J.1
Salud, A.2
Escudero, P.3
-
22
-
-
22244477362
-
Capecitabine plus oxaliplatin for the first-line treatment of elderly patients with metastatic colorectal cancer. Final results of the Southern Italy Cooperative Oncology Group (SICOG) trial 0108
-
Comella P, Natale D, Farris A, et al. Capecitabine plus oxaliplatin for the first-line treatment of elderly patients with metastatic colorectal cancer. Final results of the Southern Italy Cooperative Oncology Group (SICOG) trial 0108. Cancer. 2005;104(2):282-289.
-
(2005)
Cancer
, vol.104
, Issue.2
, pp. 282-289
-
-
Comella, P.1
Natale, D.2
Farris, A.3
-
23
-
-
34948857445
-
Capecitabine plus oxaliplatin compared with fluorouracil and leucovorin plus oxaliplatin: A randomized comparison in metastatic colorectal cancer - A final report of the AIO Colorectal Study Group
-
Porschen R, Arkenau H-T, Kubicka S, et al. Capecitabine plus oxaliplatin compared with fluorouracil and leucovorin plus oxaliplatin: A randomized comparison in metastatic colorectal cancer - A final report of the AIO Colorectal Study Group. J Clin Oncol. 2007;25(27):4217-4223.
-
(2007)
J Clin Oncol
, vol.25
, Issue.27
, pp. 4217-4223
-
-
Porschen, R.1
Arkenau, H.-T.2
Kubicka, S.3
-
24
-
-
34948892881
-
Phase III study of capecitabine plus oxaliplatin versus continuous-infusion fluorouracil plus oxaliplatin as first-line therapy in metastatic colorectal cancer: Final report of the Spanish Cooperative Group for the Treatment of Digestive Tumors Trial
-
Díaz-Rubio E, Tabernero J, Gómez-Espa a J, et al. Phase III study of capecitabine plus oxaliplatin versus continuous-infusion fluorouracil plus oxaliplatin as first-line therapy in metastatic colorectal cancer: Final report of the Spanish Cooperative Group for the Treatment of Digestive Tumors Trial. J Clin Oncol. 2007;25(27):4224-4230.
-
(2007)
J Clin Oncol
, vol.25
, Issue.27
, pp. 4224-4230
-
-
Díaz-Rubio, E.1
Tabernero, J.2
Gómez-Espa a, J.3
-
25
-
-
65849108886
-
Randomised trial comparing biweekly oxaliplatin plus oral capecitabine versus oxaliplatin plus i.v. bolus fluorouracil/leucovorin in metastatic colorectal cancer patients. Results of the Southern Italy Cooperative oncology Group study 0401
-
Comella P, Massidda B, Filippelli G, et al. Randomised trial comparing biweekly oxaliplatin plus oral capecitabine versus oxaliplatin plus i.v. bolus fluorouracil/leucovorin in metastatic colorectal cancer patients. Results of the Southern Italy Cooperative oncology Group study 0401. J Cancer Res Clin Oncol. 2009;135(2):217-226.
-
(2009)
J Cancer Res Clin Oncol
, vol.135
, Issue.2
, pp. 217-226
-
-
Comella, P.1
Massidda, B.2
Filippelli, G.3
-
26
-
-
42949150908
-
Randomized phase III study of capecitabine plus oxaliplatin compared with fluorouracil/folinic acid plus oxaliplatin as first-line therapy for metastatic colorectal cancer
-
Cassidy J, Clarke S, Díaz-Rubio E, et al. Randomized phase III study of capecitabine plus oxaliplatin compared with fluorouracil/folinic acid plus oxaliplatin as first-line therapy for metastatic colorectal cancer. J Clin Oncol. 2008;26(12):2006-2012.
-
(2008)
J Clin Oncol
, vol.26
, Issue.12
, pp. 2006-2012
-
-
Cassidy, J.1
Clarke, S.2
Díaz-Rubio, E.3
-
27
-
-
58049194302
-
Efficacy of oxaliplatin plus capecitabine or infusional fluorouracil/leucovorin in patients with metastatic colorectal cancer: A pooled analysis of randomized trials
-
Arkenau H-T, Arnold D, Cassidy J, et al. Efficacy of oxaliplatin plus capecitabine or infusional fluorouracil/leucovorin in patients with metastatic colorectal cancer: A pooled analysis of randomized trials. J Clin Oncol. 2008;26(36):5910-5917.
-
(2008)
J Clin Oncol
, vol.26
, Issue.36
, pp. 5910-5917
-
-
Arkenau, H.-T.1
Arnold, D.2
Cassidy, J.3
-
28
-
-
53049092394
-
Capecitabine plus oxaliplatin (XELOX) versus 5-fluorouracil/folinic acid plus oxaliplatin (FOLFOX-4) as second-line therapy in metastatic colorectal cancer: A randomized phase III noninferiority study
-
Rothenberg ML, Cox JV, Butts C, et al. Capecitabine plus oxaliplatin (XELOX) versus 5-fluorouracil/folinic acid plus oxaliplatin (FOLFOX-4) as second-line therapy in metastatic colorectal cancer: a randomized phase III noninferiority study. Ann Oncol. 2008;19(10):1720-1726.
-
(2008)
Ann Oncol
, vol.19
, Issue.10
, pp. 1720-1726
-
-
Rothenberg, M.L.1
Cox, J.V.2
Butts, C.3
-
29
-
-
0029972388
-
A phase I and pharmacokinetic study of oral uracil, ftorafur, and leucovorin in patients with advanced cancer
-
Meropol NJ, Rustum YM, Petrelli NJ, et al. A phase I and pharmacokinetic study of oral uracil, ftorafur, and leucovorin in patients with advanced cancer. Cancer Chemother Pharmacol. 1996;37(6):581-586.
-
(1996)
Cancer Chemother Pharmacol
, vol.37
, Issue.6
, pp. 581-586
-
-
Meropol, N.J.1
Rustum, Y.M.2
Petrelli, N.J.3
-
30
-
-
0030639034
-
UFT modulated with leucovorin in advanced colorectal cancer: Oncopaz experience
-
González-Barón M, Feliu J, Garcia Girón C, et al. UFT modulated with leucovorin in advanced colorectal cancer: Oncopaz experience. Oncology. 1997;54(Suppl 1):24-29.
-
(1997)
Oncology
, vol.54
, Issue.SUPPL. 1
, pp. 24-29
-
-
González-Barón, M.1
Feliu, J.2
Garcia Girón, C.3
-
31
-
-
0028820944
-
A fixed-ratio combination of uracil and ftorafur (UFT) with low dose leucovorin
-
Saltz LB, Leichman CG, Young CW, et al. A fixed-ratio combination of uracil and ftorafur (UFT) with low dose leucovorin. Cancer. 1995;75(3):782-785.
-
(1995)
Cancer
, vol.75
, Issue.3
, pp. 782-785
-
-
Saltz, L.B.1
Leichman, C.G.2
Young, C.W.3
-
32
-
-
0028099423
-
Phase II study of uracil and tegafur plus oral leucovorin: An effective oral regimen in the treatment of metastatic colorectal cancer
-
Pazdur R, Lassere Y, Rhodes V, et al. Phase II study of uracil and tegafur plus oral leucovorin: An effective oral regimen in the treatment of metastatic colorectal cancer. J Clin Oncol. 1994;12(11):2296-2300.
-
(1994)
J Clin Oncol
, vol.12
, Issue.11
, pp. 2296-2300
-
-
Pazdur, R.1
Lassere, Y.2
Rhodes, V.3
-
33
-
-
0036727089
-
Randomized comparative study of tegafur/uracil and oral leucovorin versus parenteral fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer
-
Carmichael J , Popiela T , Radstone D, et al. Randomized comparative study of tegafur/uracil and oral leucovorin versus parenteral fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer. J Clin Oncol. 2002;20(17):3617-3627.
-
(2002)
J Clin Oncol
, vol.20
, Issue.17
, pp. 3617-3627
-
-
Carmichael, J.1
Popiela, T.2
Radstone, D.3
-
34
-
-
0036731818
-
Multicenter phase III study of uracil/tegafur and oral leucovorin versus fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer
-
Douillard J-Y, Hoff PM, Skillings JR, et al. Multicenter phase III study of uracil/tegafur and oral leucovorin versus fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer. J Clin Oncol. 2002;20(17):3605-3616.
-
(2002)
J Clin Oncol
, vol.20
, Issue.17
, pp. 3605-3616
-
-
Douillard, J.-Y.1
Hoff, P.M.2
Skillings, J.R.3
-
35
-
-
30644475407
-
A phase II study of oral uracil/ftorafur (UFTs) plus leucovorin combined with oxaliplatin (TEGAFOX) as first-line treatment in patients with metastatic colorectal cancer
-
Bennouna J, Perrier H, Paillot B, et al. A phase II study of oral uracil/ftorafur (UFTs) plus leucovorin combined with oxaliplatin (TEGAFOX) as first-line treatment in patients with metastatic colorectal cancer. Br J Cancer. 2006;94(1):69-73.
-
(2006)
Br J Cancer
, vol.94
, Issue.1
, pp. 69-73
-
-
Bennouna, J.1
Perrier, H.2
Paillot, B.3
-
36
-
-
10844241474
-
Phase II study of UFT and oxaliplatin in first-line treatment of advanced colorectal cancer
-
Feliu J, Vicent JM, García-Girón C, et al. Phase II study of UFT and oxaliplatin in first-line treatment of advanced colorectal cancer. Br J Cancer. 2004;91(10):1758-1762.
-
(2004)
Br J Cancer
, vol.91
, Issue.10
, pp. 1758-1762
-
-
Feliu, J.1
Vicent, J.M.2
García-Girón, C.3
-
37
-
-
33846821578
-
Uracil/ftorafur/leucovorin combined with irinotecan (TEGAFIRI) or oxaliplatin (TEGAFOX) as first-line treatment for metastatic colorectal cancer patients: Results of randomised phase II study
-
Bajetta E, Di Bartolomeo M, Buzzoni R, et al. Uracil/ftorafur/leucovorin combined with irinotecan (TEGAFIRI) or oxaliplatin (TEGAFOX) as first-line treatment for metastatic colorectal cancer patients: results of randomised phase II study. Br J Cancer. 2007;96(3):439-444.
-
(2007)
Br J Cancer
, vol.96
, Issue.3
, pp. 439-444
-
-
Bajetta, E.1
Di Bartolomeo, M.2
Buzzoni, R.3
-
38
-
-
0036787717
-
Biweekly chemotherapy with oxaliplatin, irinotecan, infusional fluorouracil, and leucovorin: A pilot study in patients with metastatic colorectal cancer
-
Falcone A, Masi G, Allegrini G, et al. Biweekly chemotherapy with oxaliplatin, irinotecan, infusional fluorouracil, and leucovorin: a pilot study in patients with metastatic colorectal cancer. J Clin Oncol. 2002;20(19):4006-4014.
-
(2002)
J Clin Oncol
, vol.20
, Issue.19
, pp. 4006-4014
-
-
Falcone, A.1
Masi, G.2
Allegrini, G.3
-
39
-
-
34249000361
-
Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: The Gruppo Oncologico Nord Ovest
-
Falcone A, Ricci S, Brunetti, et al. Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: the Gruppo Oncologico Nord Ovest. J Clin Oncol. 2007;25(13):1670-1676.
-
(2007)
J Clin Oncol
, vol.25
, Issue.13
, pp. 1670-1676
-
-
Falcone, A.1
Ricci, S.2
Brunetti3
-
40
-
-
33645309877
-
FOLFOXIRI (folinic acid, 5-fluorouracil, oxaliplatin and irinotecan) vs FOLFIRI (folinic acid, 5-fluorouracil and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): A multicentre randomised phase III trial from the Hellenic Oncology Research Group (HORG)
-
Souglakos J, Androulakis N, Syrigos K, et al. FOLFOXIRI (folinic acid, 5-fluorouracil, oxaliplatin and irinotecan) vs FOLFIRI (folinic acid, 5-fluorouracil and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): a multicentre randomised phase III trial from the Hellenic Oncology Research Group (HORG). Br J Cancer. 2006;94(6):798-805.
-
(2006)
Br J Cancer
, vol.94
, Issue.6
, pp. 798-805
-
-
Souglakos, J.1
Androulakis, N.2
Syrigos, K.3
-
41
-
-
38449107093
-
Capecitabine plus oxaliplatin and irinotecan regimen every other week: A phase I/II study in first-line treatment of metastatic colorectal cancer
-
Bajetta E, Celio L, Ferrario E, et al. Capecitabine plus oxaliplatin and irinotecan regimen every other week: a phase I/II study in first-line treatment of metastatic colorectal cancer. Ann Oncol. 2007;18(11):1810-1816.
-
(2007)
Ann Oncol
, vol.18
, Issue.11
, pp. 1810-1816
-
-
Bajetta, E.1
Celio, L.2
Ferrario, E.3
-
42
-
-
61449180226
-
A dose finding and pharmacokinetic study of capecitabine in combination with oxaliplatin and irinotecan in metastatic colorectal cancer
-
Oct 7 [Epub ahead of print, DOI 10.1007/s00280-008-0840-5
-
Fornaro L, Masi G, Bursi S, et al. A dose finding and pharmacokinetic study of capecitabine in combination with oxaliplatin and irinotecan in metastatic colorectal cancer. Cancer Chemother Pharmacol. 2008 Oct 7 [Epub ahead of print]. DOI 10.1007/s00280-008-0840-5.
-
(2008)
Cancer Chemother Pharmacol
-
-
Fornaro, L.1
Masi, G.2
Bursi, S.3
-
43
-
-
36749067866
-
Phase II Trial of Cetuximab in combination with fluorouracil, leucovorin, and oxaliplatin in the first-line treatment of metastatic colorectal cancer
-
Tabernero J, Van Cutsem E, Diaz-Rubio E, et al. Phase II Trial of Cetuximab in combination with fluorouracil, leucovorin, and oxaliplatin in the first-line treatment of metastatic colorectal cancer. J Clin Oncol. 2007;25(33):5225-5232.
-
(2007)
J Clin Oncol
, vol.25
, Issue.33
, pp. 5225-5232
-
-
Tabernero, J.1
Van Cutsem, E.2
Diaz-Rubio, E.3
-
44
-
-
33847261015
-
Phase II trial of capecitabine and oxaliplatin (CAPOX) plus cetuximab in patients with metastatic colorectal cancer who progressed after oxaliplatin-based chemotherapy
-
Souglakos J, Kalykaki A, Vamvakas L, et al. Phase II trial of capecitabine and oxaliplatin (CAPOX) plus cetuximab in patients with metastatic colorectal cancer who progressed after oxaliplatin-based chemotherapy. Ann Oncol. 2007;18(2):305-310.
-
(2007)
Ann Oncol
, vol.18
, Issue.2
, pp. 305-310
-
-
Souglakos, J.1
Kalykaki, A.2
Vamvakas, L.3
-
45
-
-
77949457915
-
-
Borner M, Mingrone W, Koeberle D, et al. The impact of cetuximab on the capecitabine plus oxaliplatin (XELOX) combination in first-line treatment of metastatic colorectal cancer (MCC): A randomized phase II trial of the Swiss Group for Clinical Cancer Research (SAKK). J Clin Oncol. 2006; ASCO Annual Meeting Proceedings, Part I, 24(18S):3551.
-
Borner M, Mingrone W, Koeberle D, et al. The impact of cetuximab on the capecitabine plus oxaliplatin (XELOX) combination in first-line treatment of metastatic colorectal cancer (MCC): A randomized phase II trial of the Swiss Group for Clinical Cancer Research (SAKK). J Clin Oncol. 2006; ASCO Annual Meeting Proceedings, Part I, 24(18S):3551.
-
-
-
-
46
-
-
77949452950
-
-
Bokemeyer C, Bondarenko I, Makhson A, et al. Cetuximab plus 5FU/FA/oxaliplatin (FOLFOX-4) versus FOLFOX-4 in the first-line treatment of metastatic colorectal cancer (mCRC): OPUS, a randomized phase II study. J Clin Oncol. 2007; ASCO Annual Meeting Proceedings, Part I, 25(18S):4035.
-
Bokemeyer C, Bondarenko I, Makhson A, et al. Cetuximab plus 5FU/FA/oxaliplatin (FOLFOX-4) versus FOLFOX-4 in the first-line treatment of metastatic colorectal cancer (mCRC): OPUS, a randomized phase II study. J Clin Oncol. 2007; ASCO Annual Meeting Proceedings, Part I, 25(18S):4035.
-
-
-
-
47
-
-
77949474287
-
-
Bokemeyer, Bondarenko I, Hartmann JT, et al. KRAS status and efficacy of first-line treatment of patients with metastatic colorectal cancer (mCRC) with FOLFOX with or without cetuximab: The OPUS experience. J Clin Oncol. 2008; ASCO Annual Meeting Proceeding, Part I, 26(15S):4000.
-
Bokemeyer, Bondarenko I, Hartmann JT, et al. KRAS status and efficacy of first-line treatment of patients with metastatic colorectal cancer (mCRC) with FOLFOX with or without cetuximab: The OPUS experience. J Clin Oncol. 2008; ASCO Annual Meeting Proceeding, Part I, 26(15S):4000.
-
-
-
-
48
-
-
42949149159
-
Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: A randomized phase III study
-
Saltz LB, Clarke S, Díaz-Rubio E, et al. Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: A randomized phase III study. J Clin Oncol. 2008;26(12):2013-2019.
-
(2008)
J Clin Oncol
, vol.26
, Issue.12
, pp. 2013-2019
-
-
Saltz, L.B.1
Clarke, S.2
Díaz-Rubio, E.3
-
49
-
-
49049105525
-
Safety and efficacy of oxaliplatin and fluoropyrimidine regimens with or without bevacizumab as first-line treatment of metastatic colorectal cancer: Results of the TREE Study
-
Hochster HS, Hart LL, Ramanathan RK, et al. Safety and efficacy of oxaliplatin and fluoropyrimidine regimens with or without bevacizumab as first-line treatment of metastatic colorectal cancer: results of the TREE Study. J Clin Oncol. 2008;26(21):3523-3529.
-
(2008)
J Clin Oncol
, vol.26
, Issue.21
, pp. 3523-3529
-
-
Hochster, H.S.1
Hart, L.L.2
Ramanathan, R.K.3
-
50
-
-
34248173883
-
Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX-4) for previously treated metastatic colorectal cancer: Results from the Eastern Cooperative Oncology Group Study E3200
-
Giantonio BJ, Catalano PJ, Meropol NJ, et al. Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX-4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. J Clin Oncol. 2007;25(12):1539-1544.
-
(2007)
J Clin Oncol
, vol.25
, Issue.12
, pp. 1539-1544
-
-
Giantonio, B.J.1
Catalano, P.J.2
Meropol, N.J.3
-
51
-
-
2542615200
-
Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer
-
André T, Boni C, Mounedji-Boudiaf L, et al. Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer. N Engl J Med. 2004;350(23):2343-2351.
-
(2004)
N Engl J Med
, vol.350
, Issue.23
, pp. 2343-2351
-
-
André, T.1
Boni, C.2
Mounedji-Boudiaf, L.3
-
52
-
-
77949446100
-
-
De Gramont A, Boni C, Navarro M, et al. Oxaliplatin/5FU/LV in adjuvant colon cancer: Updated efficacy results of the MOSAIC trial, including survival, with a median follow-up of six years. J Clin Oncol. 2007; ASCO Annual Meeting Proceeding, Part I, 25(15S):4007.
-
De Gramont A, Boni C, Navarro M, et al. Oxaliplatin/5FU/LV in adjuvant colon cancer: Updated efficacy results of the MOSAIC trial, including survival, with a median follow-up of six years. J Clin Oncol. 2007; ASCO Annual Meeting Proceeding, Part I, 25(15S):4007.
-
-
-
-
53
-
-
34250210799
-
Oxaliplatin combined with weekly bolus fluorouracil and leucovorin as surgical adjuvant chemotherapy for stage II and III colon cancer: Results from NSABP C-07
-
Kuebler JP, Wieand HS, O'Connell MJ, et al. Oxaliplatin combined with weekly bolus fluorouracil and leucovorin as surgical adjuvant chemotherapy for stage II and III colon cancer: Results from NSABP C-07. J Clin Oncol. 2007;25(16):2198-2204.
-
(2007)
J Clin Oncol
, vol.25
, Issue.16
, pp. 2198-2204
-
-
Kuebler, J.P.1
Wieand, H.S.2
O'Connell, M.J.3
-
54
-
-
77949464073
-
-
Schmoll HJ, Tabernero J, Nowacki M, et al. Final safety findings from a randomized phase III trial of capecitabine + oxaliplatin (XELOX) vs. bolus 5-FU/LV as adjuvant therapy for patients (pts) with stage III colon cancer. J Clin Oncol. 2006; ASCO Annual Meeting Proceedings, Part I, 24(18S):3569.
-
Schmoll HJ, Tabernero J, Nowacki M, et al. Final safety findings from a randomized phase III trial of capecitabine + oxaliplatin (XELOX) vs. bolus 5-FU/LV as adjuvant therapy for patients (pts) with stage III colon cancer. J Clin Oncol. 2006; ASCO Annual Meeting Proceedings, Part I, 24(18S):3569.
-
-
-
-
55
-
-
77949458349
-
-
Allegra CJ, Yothers G, O'Connell MJ, Sharif S, Wolmark N. Initial safety report of NSABP C-08, a randomized phase III study of modified 5-fluorouracil (5-FU)/leucovorin (LCV) and oxaliplatin (OX) (mFOLFOX6) with or without bevacizumab (bev) in the adjuvant treatment of patients with stage II/III colon cancer. J Clin Oncol. 2008; ASCO Annual Meeting Proceeding, Part I, 26(15S):4006.
-
Allegra CJ, Yothers G, O'Connell MJ, Sharif S, Wolmark N. Initial safety report of NSABP C-08, a randomized phase III study of modified 5-fluorouracil (5-FU)/leucovorin (LCV) and oxaliplatin (OX) (mFOLFOX6) with or without bevacizumab (bev) in the adjuvant treatment of patients with stage II/III colon cancer. J Clin Oncol. 2008; ASCO Annual Meeting Proceeding, Part I, 26(15S):4006.
-
-
-
-
56
-
-
3042523914
-
Prevention of oxaliplatin-related neurotoxicity by calcium and magnesium infusions: A retrospective study of 161 patients receiving oxaliplatin combined with 5-Fluorouracil and leucovorin for advanced colorectal cancer
-
Gamelin L Boisdron-Celle M, Delva R. Prevention of oxaliplatin-related neurotoxicity by calcium and magnesium infusions: a retrospective study of 161 patients receiving oxaliplatin combined with 5-Fluorouracil and leucovorin for advanced colorectal cancer. Clin Cancer Res. 2004;15;10:4055-4061.
-
(2004)
Clin Cancer Res
, vol.15
, Issue.10
, pp. 4055-4061
-
-
Gamelin, L.1
Boisdron-Celle, M.2
Delva, R.3
-
57
-
-
77949428016
-
-
Nickevich DA, Grothey A, Sloan JA, et al. Effect of intravenous calcium and magnesium (IV CaMg) on oxaliplatin-induced sensory neurotoxicity (sNT) in adjuvant colon cancer: Results of the phase III placebo-controlled, double blind NCCTG trial N04c7. J Clin Oncol. 2008; ASCO Annual Meeting Proceeding, Part I, 26(15S):4009.
-
Nickevich DA, Grothey A, Sloan JA, et al. Effect of intravenous calcium and magnesium (IV CaMg) on oxaliplatin-induced sensory neurotoxicity (sNT) in adjuvant colon cancer: Results of the phase III placebo-controlled, double blind NCCTG trial N04c7. J Clin Oncol. 2008; ASCO Annual Meeting Proceeding, Part I, 26(15S):4009.
-
-
-
-
58
-
-
77949448392
-
-
Grothey A, Hart LL, Rowland KM, et al. Intermittent oxaliplatin (oxali) and time-to-treatment-failure (TTF) in metastatic colorectal cancer (mCRC): Final results of the phase III CONcePT trial. J Clin Oncol. 2008; ASCO Annual Meeting Proceeding, Part I, 26(15S):4010.
-
Grothey A, Hart LL, Rowland KM, et al. Intermittent oxaliplatin (oxali) and time-to-treatment-failure (TTF) in metastatic colorectal cancer (mCRC): Final results of the phase III CONcePT trial. J Clin Oncol. 2008; ASCO Annual Meeting Proceeding, Part I, 26(15S):4010.
-
-
-
-
59
-
-
77949434294
-
-
Cassidy J, Bjarnason GA, Hickish T, et al: Randomized double blind (DB) placebo (Plcb) controlled phase III study assessing the efficacy of xaliproden (X) in reducing the cumulative peripheral sensory neuropathy (PSN) induced by the oxaliplatin (Ox) and 5-FU/LV combination (FOLFOX-4) in first-line treatment of patients (pts) with metastatic colorectal cancer (MCRC). J Clin Oncol. 2006; ASCO Annual Meeting Proceedings, Part I, 24(18S):3507.
-
Cassidy J, Bjarnason GA, Hickish T, et al: Randomized double blind (DB) placebo (Plcb) controlled phase III study assessing the efficacy of xaliproden (X) in reducing the cumulative peripheral sensory neuropathy (PSN) induced by the oxaliplatin (Ox) and 5-FU/LV combination (FOLFOX-4) in first-line treatment of patients (pts) with metastatic colorectal cancer (MCRC). J Clin Oncol. 2006; ASCO Annual Meeting Proceedings, Part I, 24(18S):3507.
-
-
-
|