A dose finding and pharmacokinetic study of capecitabine in combination with oxaliplatin and irinotecan in metastatic colorectal cancer

Cancer Chemotherapy and Pharmacology

Volumn 63, Issue 5, 2009, Pages 965-969

  Fornaro, Lorenzo ^a   Masi, G ^a   Bursi, S ^a   Loupakis, F ^a   Vasile, E ^a   Antonuzzo, A ^a   Chiara, S ^b   Pfanner, E ^c   Di Paolo, A ^d   Bocci, G ^d   Del Tacca, M ^d   Falcone, A ^a,d  

^a ISTITUTO TOSCANO TUMORI   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c UNIVERSITY HOSPITAL OF PISA   (Italy)

^d UNIVERSITY OF PISA   (Italy)

Author keywords

Capecitabine; Dose finding; Irinotecan; Metastatic colorectal cancer; Oxaliplatin; Triplet regimen

Indexed keywords

CAPECITABINE; IRINOTECAN; OXALIPLATIN;

ADULT; AGED; ARTICLE; BLOOD SAMPLING; CANCER SURVIVAL; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; DIARRHEA; DRUG DOSE ESCALATION; DRUG METABOLISM; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; FEVER; HAND FOOT SYNDROME; HUMAN; MALE; METASTASIS; MULTIPLE CYCLE TREATMENT; NAUSEA; NEUROTOXICITY; NEUTROPENIA; PRIORITY JOURNAL; THROMBOCYTOPENIA; TREATMENT RESPONSE;

ADOLESCENT; ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BONE NEOPLASMS; CAMPTOTHECIN; COLORECTAL NEOPLASMS; DEOXYCYTIDINE; DISEASE-FREE SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEASIBILITY STUDIES; FEMALE; FLUOROURACIL; HUMANS; LIVER NEOPLASMS; LUNG NEOPLASMS; LYMPHATIC METASTASIS; MAXIMUM TOLERATED DOSE; MIDDLE AGED; NEOPLASM STAGING; ORGANOPLATINUM COMPOUNDS; PLEURAL NEOPLASMS; SURVIVAL RATE; TREATMENT OUTCOME; YOUNG ADULT;

EID: 61449180226     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-008-0840-5     Document Type: Article

References (16)

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