Whole brain radiotherapy with a conformational external beam radiation boost for lung cancer patients with 1-3 brain metastasis: A multi institutional study

Radiation Oncology

Volumn 5, Issue 1, 2010, Pages

  Casanova, Nathalie ^a   Mazouni, Zohra ^b   Bieri, Sabine ^c   Combescure, Christophe ^a   Pica, Alessia ^b   Weber, Damien C ^a,d  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^c Sion Cantonal Hospital   (Switzerland)

^d UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ALOPECIA; ARTICLE; ASTHENIA; BRAIN DYSFUNCTION; BRAIN METASTASIS; BRAIN RADIATION; CANCER CONTROL; CONTROLLED STUDY; DISEASE COURSE; EXTERNAL BEAM RADIOTHERAPY; FEMALE; FOLLOW UP; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PROGNOSIS; RADIATION DOSE; RADIATION INJURY; SIMULATION; TREATMENT FAILURE; BRAIN TUMOR; CLINICAL TRIAL; COMPUTER ASSISTED RADIOTHERAPY; KAPLAN MEIER METHOD; LUNG TUMOR; METASTASIS; METHODOLOGY; MIDDLE AGED; MORTALITY; MULTICENTER STUDY; PATHOLOGY; RETROSPECTIVE STUDY; SKULL IRRADIATION;

ADULT; AGED; BRAIN NEOPLASMS; CRANIAL IRRADIATION; FEMALE; HUMANS; KAPLAN-MEIERS ESTIMATE; LUNG NEOPLASMS; MALE; MIDDLE AGED; RADIOTHERAPY, CONFORMAL; RETROSPECTIVE STUDIES;

EID: 77949427305     PISSN: None     EISSN: 1748717X     Source Type: Journal    
DOI: 10.1186/1748-717X-5-13     Document Type: Article

References (28)

1. Rades D, Pluemer A, Veninga T, Dunst J, Schild SE. A boost in addition to whole-brain radiotherapy improves patient outcome after resection of 1 or 2 brain metastases in recursive partitioning analysis class 1 and 2 patients. Cancer 2007, 110:1551-1559. 10.1002/cncr.22960, 17654659.
2. Johnson JD, Young B. Demographics of brain metastasis. Neurosurgery clinics of North America 1996, 7:337-344.
3. Gercovich FG, Luna MA, Gottlieb JA. Increased incidence of cerebral metastases in sarcoma patients with prolonged survival from chemotherapy. Report of cases of leiomysarcoma and chondrosarcoma. Cancer 1975, 36:1843-1851. 10.1002/1097-0142(197511)36:5<1843::AID-CNCR2820360541CO;2-V, 1192369.
4. Ryberg M, Nielsen D, Osterlind K, Andersen PK, Skovsgaard T, Dombernowsky P. Predictors of central nervous system metastasis in patients with metastatic breast cancer. A competing risk analysis of 579 patients treated with epirubicin-based chemotherapy. Breast cancer research and treatment 2005, 91:217-225. 10.1007/s10549-005-0323-x, 15952055.
5. Duchnowska R, Szczylik C. Central nervous system metastases in breast cancer patients administered trastuzumab. Cancer treatment reviews 2005, 31:312-318. 10.1016/j.ctrv.2005.04.008, 15979804.
6. Sundstrom JT, Minn H, Lertola KK, Nordman E. Prognosis of patients treated for intracranial metastases with whole-brain irradiation. Annals of medicine 1998, 30:296-299. 10.3109/07853899809005858, 9677016.
7. Zimm S, Wampler GL, Stablein D, Hazra T, Young HF. Intracerebral metastases in solid-tumor patients: natural history and results of treatment. Cancer 1981, 48:384-394. 10.1002/1097-0142(19810715)48:2<384::AID-CNCR2820480227CO;2-8, 7237407.
8. Lagerwaard FJ, Levendag PC, Nowak PJ, Eijkenboom WM, Hanssens PE, Schmitz PI. Identification of prognostic factors in patients with brain metastases: a review of 1292 patients. International journal of radiation oncology biology, physics 1999, 43:795-803.
9. Barnes EA, Chow E, Tsao MN, Bradley NM, Doyle M, Li K, Lam K, Danjoux C. Physician Expectations of Treatment Outcomes for Patients with Brain Metastases Referred for Whole Brain Radiotherapy. International journal of radiation oncology, biology, physics 2010, 76:187-192.
10. Andrews DW, Scott CB, Sperduto PW, Flanders AE, Gaspar LE, Schell MC, Werner-Wasik M, Demas W, Ryu J, Bahary JP, Souhami L, Rotman M, Mehta MP, Curran WJ. Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: phase III results of the RTOG 9508 randomised trial. Lancet 2004, 363:1665-1672. 10.1016/S0140-6736(04)16250-8, 15158627.
11. Kondziolka D, Patel A, Lunsford LD, Kassam A, Flickinger JC. Stereotactic radiosurgery plus whole brain radiotherapy versus radiotherapy alone for patients with multiple brain metastases. International journal of radiation oncology, biology, physics 1999, 45:427-434.
12. Meyers CA, Smith JA, Bezjak A, Mehta MP, Liebmann J, Illidge T, Kunkler I, Caudrelier JM, Eisenberg PD, Meerwaldt J, Siemers R, Carrie C, Gaspar LE, Curran W, Phan SC, Miller RA, Renschler MF. Neurocognitive function and progression in patients with brain metastases treated with whole-brain radiation and motexafin gadolinium: results of a randomized phase III trial. J Clin Oncol 2004, 22:157-165. 10.1200/JCO.2004.05.128, 14701778.
13. Li J, Bentzen SM, Li J, Renschler M, Mehta MP. Relationship between neurocognitive function and quality of life after whole-brain radiotherapy in patients with brain metastasis. International journal of radiation oncology, biology, physics 2008, 71:64-70.
14. Sham JS, Lau WH, Tung Y. Radiotherapy of brain metastases from carcinoma of the bronchus. Clinical radiology 1989, 40:193-194. 10.1016/S0009-9260(89)80093-5, 2494013.
15. Egawa S, Tukiyama I, Akine Y, Kajiura Y, Yanagawa S, Watai K, Nomura K. Radiotherapy of brain metastases. International journal of radiation oncology, biology, physics 1986, 12:1621-1625.
16. D'Elia F, Bonucci I, Biti GP, Pirtoli L. Different fractionation schedules in radiation treatment of cerebral metastases. Acta radiologica 1986, 25:181-184.
17. Chatani M, Teshima T, Hata K, Inoue T, Suzuki T. Whole brain irradiation for metastases from lung carcinoma. A clinical investigation. Acta radiologica 1985, 24:311-314.
18. Harwood AR, Simson WJ. Radiation therapy of cerebral metastases: a randomized prospective clinical trial. International journal of radiation oncology, biology, physics 1977, 2:1091-1094.
19. Borgelt B, Gelber R, Kramer S, Brady LW, Chang CH, Davis LW, Perez CA, Hendrickson FR. The palliation of brain metastases: final results of the first two studies by the Radiation Therapy Oncology Group. International journal of radiation oncology, biology, physics 1980, 6:1-9.
20. Gaspar L, Scott C, Rotman M, Asbell S, Phillips T, Wasserman T, McKenna WG, Byhardt R. Recursive partitioning analysis (RPA) of prognostic factors in three Radiation Therapy Oncology Group (RTOG) brain metastases trials. International journal of radiation oncology, biology, physics 1997, 37:745-751.
21. Sperduto PW, Berkey B, Gaspar LE, Mehta M, Curran W. A New Prognostic Index and Comparison to Three Other Indices for Patients With Brain Metastases: An Analysis of 1,960 Patients in the RTOG Database. International journal of radiation oncology, biology, physics 2008, 70:510-514.
22. Roberge D, Petrecca K, El Refae M, Souhami L. Whole-brain radiotherapy and tumor bed radiosurgery following resection of solitary brain metastases. Journal of neuro-oncology 2009,
23. Kim YS, Kondziolka D, Flickinger JC, Lunsford LD. Stereotactic radiosurgery for patients with nonsmall cell lung carcinoma metastatic to the brain. Cancer 1997, 80:2075-2083. 10.1002/(SICI)1097-0142(19971201)80:11<2075::AID-CNCR6CO;2-W, 9392329.
24. Ma S, Xu Y, Deng Q, Yu X. Treatment of brain metastasis from non-small cell lung cancer with whole brain radiotherapy and Gefitinib in a Chinese population. Lung cancer (Amsterdam, Netherlands) 2009, 65:198-203.
25. Hoskin PJ, Crow J, Ford HT. The influence of extent and local management on the outcome of radiotherapy for brain metastases. International journal of radiation oncology, biology, physics 1990, 19:111-115.
26. Rades D, Kueter JD, Pluemer A, Veninga T, Schild SE. A matched-pair analysis comparing whole-brain radiotherapy plus stereotactic radiosurgery versus surgery plus whole-brain radiotherapy and a boost to the metastatic site for one or two brain metastases. International journal of radiation oncology, biology, physics 2009, 73:1077-1081.
27. Regine WF, Scott C, Murray K, Curran W. Neurocognitive outcome in brain metastases patients treated with accelerated-fractionation vs. accelerated-hyperfractionated radiotherapy: an analysis from Radiation Therapy Oncology Group Study 91-04. International journal of radiation oncology, biology, physics 2001, 51:711-717.
28. Peduzzi P, Concato J, Kemper E, Holford TR, Feinstein AR. A simulation study of the number of events per variable in logistic regression analysis. Journal of clinical epidemiology 1996, 49:1373-1379. 10.1016/S0895-4356(96)00236-3, 8970487.