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Volumn 45, Issue 3, 2010, Pages 543-549

Lack of prompt expansion of cytomegalovirus pp65 and IE-1-specific IFN CD8 and CD4 T cells is associated with rising levels of pp65 antigenemia and DNAemia during pre-emptive therapy in allogeneic hematopoietic stem cell transplant recipients

Author keywords

Cytomegalovirus; IFN CD8+ and CD4+ T cells rising antigenemia; Stem cell transplantation

Indexed keywords

BUSULFAN; CD4 ANTIGEN; CD8 ANTIGEN; CORTICOSTEROID; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; CYTOMEGALOVIRUS ANTIGEN PP65; FLUDARABINE; FOSCARNET; GAMMA INTERFERON; GANCICLOVIR; MELPHALAN; METHOTREXATE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; THIOTEPA; THYMOCYTE ANTIBODY; VALGANCICLOVIR; VIRUS DNA;

EID: 77949423996     PISSN: 02683369     EISSN: 14765365     Source Type: Journal    
DOI: 10.1038/bmt.2009.172     Document Type: Article
Times cited : (51)

References (19)
  • 1
    • 0029800728 scopus 로고    scopus 로고
    • Cytomegalovirus pp65 antigenemia-guided early treatment with ganciclovir versus ganciclovir at engraftment after allogeneic marrow transplantation: A randomized double-blind study
    • Boeckh M, Gooley TA, Myerson D, Cunningham T, Schoch G, Bowden RA. Cytomegalovirus pp65 antigenemia-guided early treatment with ganciclovir versus ganciclovir at engraftment after allogeneic marrow transplantation: a randomized double-blind study. Blood 1996; 88: 4063-4071.
    • (1996) Blood , vol.88 , pp. 4063-4071
    • Boeckh, M.1    Gooley, T.A.2    Myerson, D.3    Cunningham, T.4    Schoch, G.5    Bowden, R.A.6
  • 2
    • 0035865528 scopus 로고    scopus 로고
    • Rising p65 antigenemia during pre-emptive anti cytomegalovirus therapy after allogeneic hematopoietic stem cell transplantation: Risk factors, correlation with DNA load, and outcomes
    • Nichols WG, Corey L, Gooley T, Drew WL, Miner R, Huang M-L et al. Rising p65 antigenemia during pre-emptive anti cytomegalovirus therapy after allogeneic hematopoietic stem cell transplantation: risk factors, correlation with DNA load, and outcomes. Blood 2001; 97: 867-874.
    • (2001) Blood , vol.97 , pp. 867-874
    • Nichols, W.G.1    Corey, L.2    Gooley, T.3    Drew, W.L.4    Miner, R.5    Huang, M.-L.6
  • 3
    • 17844364640 scopus 로고    scopus 로고
    • Rising antigenemia levels may be misleading in pre-emptive therapy of human cytomegalovirus infection in allogeneic hematopoietic stem cell transplant recipients
    • Gerna G, Lilleri D, Zecca M, Alessandrino EP, Baldanti F, Revello MG et al. Rising antigenemia levels may be misleading in pre-emptive therapy of human cytomegalovirus infection in allogeneic hematopoietic stem cell transplant recipients. Haematologica 2005; 90: 526-533.
    • (2005) Haematologica , vol.90 , pp. 526-533
    • Gerna, G.1    Lilleri, D.2    Zecca, M.3    Alessandrino, E.P.4    Baldanti, F.5    Revello, M.G.6
  • 4
    • 0035383765 scopus 로고    scopus 로고
    • Frequent detection of rising cytomegalovirus antigenemia after allogeneic stem cell transplantation following a regimen containing antithymocyte globulin
    • Kanda Y, Mineishi S, Nakai K, Saito T, Tanosaki R, Takaue Y. Frequent detection of rising cytomegalovirus antigenemia after allogeneic stem cell transplantation following a regimen containing antithymocyte globulin. Blood 2001; 97: 3676-3677.
    • (2001) Blood , vol.97 , pp. 3676-3677
    • Kanda, Y.1    Mineishi, S.2    Nakai, K.3    Saito, T.4    Tanosaki, R.5    Takaue, Y.6
  • 5
    • 14744270979 scopus 로고    scopus 로고
    • Human cytomegalovirus resistance to antiviral drugs
    • Gilbert C, Boivin G. Human cytomegalovirus resistance to antiviral drugs. Antimicrob Agents Chemother 2005; 49: 873-883.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 873-883
    • Gilbert, C.1    Boivin, G.2
  • 6
    • 0031944950 scopus 로고    scopus 로고
    • Rising levels of human cytomegalovirus (HCMV) antigenemia during initial antiviral treatment of solid-organ transplant recipients with primary HCMV infection
    • Gerna G, Zavattoni M, Percivalle E, Grossi P, Torsellini M, Revello MG. Rising levels of human cytomegalovirus (HCMV) antigenemia during initial antiviral treatment of solid-organ transplant recipients with primary HCMV infection. J Clin Microbiol 1998; 36: 1113-1116.
    • (1998) J Clin Microbiol , vol.36 , pp. 1113-1116
    • Gerna, G.1    Zavattoni, M.2    Percivalle, E.3    Grossi, P.4    Torsellini, M.5    Revello, M.G.6
  • 7
    • 0346256762 scopus 로고    scopus 로고
    • In vitro model for the study of the dissociation of increasing antigenemia and decreasing DNAemia and viremia during treatment of human cytomegalovirus infection with ganciclovir in transplant patients
    • Gerna G, Sarasini A, Lilleri D, Percivalle E, Torsellini M, Baldanti F et al. In vitro model for the study of the dissociation of increasing antigenemia and decreasing DNAemia and viremia during treatment of human cytomegalovirus infection with ganciclovir in transplant patients. J Infect Dis 2003; 188: 1639-1647.
    • (2003) J Infect Dis , vol.188 , pp. 1639-1647
    • Gerna, G.1    Sarasini, A.2    Lilleri, D.3    Percivalle, E.4    Torsellini, M.5    Baldanti, F.6
  • 9
    • 0034764729 scopus 로고    scopus 로고
    • Qualitative plasma assay (AMPLICOR CMV test) versus pp65 antigenemia assay for monitoring cytomegalovirus viremia and guiding preemptive ganciclovir therapy in allogeneic stem cell transplantation
    • Solano C, Muñoz I, Gutiérrez A, Farga A, Pró sper F, García- Conde J et al. Qualitative plasma assay (AMPLICOR CMV test) versus pp65 antigenemia assay for monitoring cytomegalovirus viremia and guiding preemptive ganciclovir therapy in allogeneic stem cell transplantation. J Clin Microbiol 2001; 39: 3938-3941.
    • (2001) J Clin Microbiol , vol.39 , pp. 3938-3941
    • Solano, C.1    Muñoz, I.2    Gutiérrez, A.3    Farga, A.4    Prósper, F.5    García-Conde, J.6
  • 10
    • 53649107879 scopus 로고    scopus 로고
    • Quantification of DNA in plasma by an automated real-time PCR assay (CMV PCR Kit, Abbott) for surveillance of active cytomegalovirus infection and guidance of preemptive therapy for allogeneic hematopoietic stem cell transplant recipients
    • Gimeno C, Solano C, Latorre JC, Herná ndez-Boluda JC, Clari MA, Remigia MJ et al. Quantification of DNA in plasma by an automated real-time PCR assay (CMV PCR Kit, Abbott) for surveillance of active cytomegalovirus infection and guidance of preemptive therapy for allogeneic hematopoietic stem cell transplant recipients. J Clin Microbiol 2008; 46: 3311-3318.
    • (2008) J Clin Microbiol , vol.46 , pp. 3311-3318
    • Gimeno, C.1    Solano, C.2    Latorre, J.C.3    Hernández-Boluda, J.C.4    Clari, M.A.5    Remigia, M.J.6
  • 11
    • 0034812453 scopus 로고    scopus 로고
    • Sequencing of cytomegalovirus UL97 gene for genotypic antiviral resistance testing
    • Lurain NS, Weinberg A, Crumpacker CS, Chou S. Sequencing of cytomegalovirus UL97 gene for genotypic antiviral resistance testing. J Clin Microbiol 2001; 45: 2775-2780.
    • (2001) J Clin Microbiol , vol.45 , pp. 2775-2780
    • Lurain, N.S.1    Weinberg, A.2    Crumpacker, C.S.3    Chou, S.4
  • 12
    • 3342964201 scopus 로고    scopus 로고
    • Cytomegalovirus antiviral resistance associated with treatment induced UL97 (protein kinase) and UL54 (DNA polymerase) mutations
    • Scott GM, Isaacs MA, Zeng F, Kesson AM, Rawlinson WD. Cytomegalovirus antiviral resistance associated with treatment induced UL97 (protein kinase) and UL54 (DNA polymerase) mutations. J Med Virol 2004; 74: 85-93.
    • (2004) J Med Virol , vol.74 , pp. 85-93
    • Scott, G.M.1    Isaacs, M.A.2    Zeng, F.3    Kesson, A.M.4    Rawlinson, W.D.5
  • 13
    • 33646827176 scopus 로고    scopus 로고
    • Rising cytomegalovirus pp65 antigenemia and DNA levels during preemptive antiviral therapy
    • Boeckh M. Rising cytomegalovirus pp65 antigenemia and DNA levels during preemptive antiviral therapy. Haematologica 2005; 90: 439-440.
    • (2005) Haematologica , vol.90 , pp. 439-440
    • Boeckh, M.1
  • 14
    • 0031821865 scopus 로고    scopus 로고
    • Quantitation of cytomegalovirus: Methodological aspects and clinical applications
    • Boeckh M, Boivin G. Quantitation of cytomegalovirus: methodological aspects and clinical applications. Clin Microbiol Rev 1998; 11: 533-554.
    • (1998) Clin Microbiol Rev , vol.11 , pp. 533-554
    • Boeckh, M.1    Boivin, G.2
  • 15
    • 0037093102 scopus 로고    scopus 로고
    • Sensitive detection of human cytomegalovirus peptide-specific cytotoxic T-lymphocyte responses by interferon- g enzyme-linked immunospot assay and flow cytometry in healthy individuals and in patients after allogeneic stem cell transplantation
    • Hebart H, Daginik S, Stevanovic S, Grigoleit U, Dobler A, Baur M et al. Sensitive detection of human cytomegalovirus peptide-specific cytotoxic T-lymphocyte responses by interferon- g enzyme-linked immunospot assay and flow cytometry in healthy individuals and in patients after allogeneic stem cell transplantation. Blood 2002; 99: 3830-3837.
    • (2002) Blood , vol.99 , pp. 3830-3837
    • Hebart, H.1    Daginik, S.2    Stevanovic, S.3    Grigoleit, U.4    Dobler, A.5    Baur, M.6
  • 16
    • 40849098721 scopus 로고    scopus 로고
    • Human cytomegalovirus-specific CD4+ and CD8+ T-cell reconstitution in adult allogeneic hematopoietic stem cell transplant recipients and immune control of viral infection
    • Lilleri D, Fornara C, Chiesa A, Caldera D, Alessandrino EP, Gerna G. Human cytomegalovirus-specific CD4+ and CD8+ T-cell reconstitution in adult allogeneic hematopoietic stem cell transplant recipients and immune control of viral infection. Haematologica 2008; 93: 248-256.
    • (2008) Haematologica , vol.93 , pp. 248-256
    • Lilleri, D.1    Fornara, C.2    Chiesa, A.3    Caldera, D.4    Alessandrino, E.P.5    Gerna, G.6
  • 17
    • 33644791359 scopus 로고    scopus 로고
    • Evaluation of cytomegalovirus-specific T-cell reconstitution in patients after various allogeneic haematopoietic stem cell transplantation using interferon- gamma-enzyme-linked immunospot and human leucocyte antigen tetramer assays with an immunodominant T-cell epitope
    • Ohnishi M, Sakurai T, Heike Y, Yamazaki R, Kanda Y, Takaue Y et al. Evaluation of cytomegalovirus-specific T-cell reconstitution in patients after various allogeneic haematopoietic stem cell transplantation using interferon- gamma-enzyme-linked immunospot and human leucocyte antigen tetramer assays with an immunodominant T-cell epitope. Br J Haematol 2005; 131: 472-479.
    • (2005) Br J Haematol , vol.131 , pp. 472-479
    • Ohnishi, M.1    Sakurai, T.2    Heike, Y.3    Yamazaki, R.4    Kanda, Y.5    Takaue, Y.6
  • 18
    • 51749112070 scopus 로고    scopus 로고
    • Patterns of cytomegalovirus reactivation are associated with distinct evolutive profiles of immune reconstitution after allogeneic hematopoietic stem cell transplantation
    • Moins-Teisserenc H, Busson M, Scieux C, Bajzik V, Cayuela JM, Clave E et al. Patterns of cytomegalovirus reactivation are associated with distinct evolutive profiles of immune reconstitution after allogeneic hematopoietic stem cell transplantation. J Infect Dis 2008; 198: 818-826.
    • (2008) J Infect Dis , vol.198 , pp. 818-826
    • Moins-Teisserenc, H.1    Busson, M.2    Scieux, C.3    Bajzik, V.4    Cayuela, J.M.5    Clave, E.6
  • 19
    • 35648960271 scopus 로고    scopus 로고
    • Evaluation of intervention strategy based on CMV-specific immune responses after allogeneic SCT
    • Avetisyan G, Aschan J, Hägglund H, Ringdén O, Ljungman P. Evaluation of intervention strategy based on CMV-specific immune responses after allogeneic SCT. Bone Marrow Transplant 2007; 40: 865-869.
    • (2007) Bone Marrow Transplant , vol.40 , pp. 865-869
    • Avetisyan, G.1    Aschan, J.2    Hägglund, H.3    Ringdén, O.4    Ljungman, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.