5-Carboxyfluorescein tagged N-phenylanthranilamide as a tracer reagent for fluorescence polarization: A robust method to screen MAPK pathway allosteric inhibitors

Chemical Communications

Volumn 46, Issue 12, 2010, Pages 2043-2045

  Rezvani, Z Nooshin ^a   Mayer, R John ^a   Chan, Weng C ^b  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

6 CARBOXYFLUORESCEIN; ANTHRANILIC ACID DERIVATIVE; FLUORESCEIN DERIVATIVE; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1 INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2 INHIBITOR; N ALPHA(FLUORESCEIN 5 CARBOXY) N EPSILON(N [ 2 FLUORO 4 IODOPHENYL] 3,4 DIFLUOROANTHANILOYL)LYSYL AMIDE; N PHENYLANTHRANILAMIDE; TRACER; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DRUG DESIGN; FLUORESCENCE POLARIZATION SPECTROSCOPY; FLUORESCENCE SPECTROSCOPY; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; SIGNAL TRANSDUCTION; X RAY ANALYSIS;

EID: 77949389636     PISSN: 13597345     EISSN: None     Source Type: Journal    
DOI: 10.1039/b925042e     Document Type: Article

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