Moderate hypothermia suppressed excessive generation of superoxide anion radical and inflammatory reactions in blood and liver in heatstroke: Laboratory study in rats

Free Radical Research

Volumn 44, Issue 4, 2010, Pages 462-472

  Todani, Masaki ^a   Fujita, Motoki ^a   Tsuruta, Ryosuke ^a   Nakahara, Takashi ^a   Yagi, Takeshi ^a   Oshima, Chiyomi ^a   Igarashi, Masatsugu ^b   Takahashi, Koshiro ^b   Kasaoka, Shunji ^a   Yuasa, Makoto ^b   Maekawa, Tsuyoshi ^a  

^a YAMAGUCHI UNIVERSITY HOSPITAL   (Japan)

^b TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

Heatstroke; High mobility group box 1 (HMGB1) protein; Hypothermia; Intercellular adhesion molecule 1 (ICAM 1); Malondialdehyde (MDA); Superoxide

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; HIGH MOBILITY GROUP B1 PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; SUPEROXIDE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL PRESSURE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLOOD; CONTROLLED STUDY; HEAT STROKE; INDUCED HYPOTHERMIA; INFLAMMATION; LIVER INJURY; MALE; NONHUMAN; RAT; TEMPERATURE DEPENDENCE;

ACIDOSIS, LACTIC; ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; HEAT STROKE; HMGB1 PROTEIN; HYPOTHERMIA, INDUCED; INFLAMMATION MEDIATORS; INTERCELLULAR ADHESION MOLECULE-1; ION-SELECTIVE ELECTRODES; LIVER; MALE; RATS; RATS, WISTAR; SUPEROXIDES; TIME FACTORS;

RATTUS;

EID: 77949364449     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.3109/10715761003610752     Document Type: Article

References (36)

1. Bouchama A, Knochel JP. Heat stroke. N Engl J Med 2002;346:1978-1988.
2. Misset B, De Jonghe B, Bastuji-Garin S, Gattolliat O, Boughrara E, Annane D, Hausfater P, Garrouste-Orgeas M, Carlet J. Mortality of patients with heatstroke admitted to intensive care units during the 2003 heat wave in France: a national multiple-center risk-factor study. Crit Care Med 2006;34:1087-1092.
3. Hall DM, Buettner GR, Oberley LW, Xu L, Matthes RD, Gisolfi CV. Mechanisms of circulatory and intestinal barrier dysfunction during whole body hyperthermia. Am J Physiol Heart Circ Physiol 2001;280:H509-H521.
4. Yang CY, Lin MT. Oxidative stress in rats with heatstroke-induced cerebral ischemia. Stroke 2002;33:790-794.
5. Lipton SA, Choi YB, Pan ZH, Lei SZ, Chen HS, Sucher NJ, Loscalzo J, Singel DJ, Stamler JS. A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. Nature 1993;364:626-632.
6. Beckman JS, Koppenol WH. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am J Physiol 1996;271:C1424-C1437.
7. Hsu SF, Niu KC, Lin CL, Lin MT. Brain cooling causes attenuation of cerebral oxidative stress, systemic infl amma-tion, activated coagulation, and tissue ischemia/injury during heatstroke. Shock 2006;26:210-220.
8. Bouchama A, Dehbi M, Chaves-Carballo E. Cooling and hemodynamic management in heatstroke: practical recommendations. Crit Care 2007;11:R54.
9. Yuasa M, Oyaizu K. Electrochemical detection and sensing of reactive oxygen species. Curr Org Chem 2005;9: 1685-1697.
10. Yuasa M, Oyaizu K, Yamaguchi A, Ishikawa M, Eguchi K, Kobayashi T, Toyoda Y, Tsutsui S. Structure and redox properties of electropolymerized fi lm obtained from iron meso-tetrakis(3-thienyl)porphyrin. Polym Adv Technol 2005;16: 616-621.
11. Yuasa M, Oyaizu K, Yamaguchi A, Ishikawa M, Eguchi K, Kobayashi T, Toyoda Y, Tsutsui S. Electrochemical sensor for superoxide anion radical using polymeric iron porphyrin complexes containing axial 1-methylimidazole ligand as cyto-chrome c mimics. Polym Adv Technol 2005;161:287-292.
12. Fujita M, Tsuruta R, Kasaoka S, Fujimoto K, Tanaka R, Oda Y, Nanba M, Igarashi M, Yuasa M, Yoshikawa T, Maekawa T. In vivo real-time measurement of superoxide anion radical with a novel electrochemical sensor. Free Radic Biol Med 2009;47:1039-1048.
13. Aki HS, Fujita M, Yamashita S, Fujimoto K, Kumagai K, Tsuruta R, Kasaoka S, Aoki T, Nanba M, Murata H, Yuasa M, Maruyama I, Maekawa T. Elevation of jugular venous super-oxide anion radical is associated with early infl ammation, oxidative stress, and endothelial injury in forebrain ischemia-reperfusion rats. Brain Res 2009;1292:180-190.
14. Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA 1990;87:1620-1624.
15. Granger DN, Kubes P. The microcirculation and infl amma-tion: modulation of leukocyte-endothelial cell adhesion. J Leukoc Biol 1994;55:662-675.
16. Droge W. Free radicals in the physiological control of cell function. Physiol Rev 2002;82:47-95.
17. Parks DA, Granger DN. Ischemia-induced vascular changes: role of xanthine oxidase and hydroxyl radicals. Am J Physiol 1983;245:G285-G289.
18. Guzik TJ, Korbut R, Adamek-Guzik T. Nitric oxide and superoxide in infl ammation and immune regulation. J Physiol Pharmacol 2003;54:469-487.
19. Babior BM, Curnutte JT, McMurrich BJ. The particulate superoxide-forming system from human neutrophils. Properties of the system and further evidence supporting its participation in the respiratory burst. J Clin Invest 1976;58: 989-996.
20. Li JM, Shah AM. Endothelial cell superoxide generation: regulation and relevance for cardiovascular pathophysiology. Am J Physiol Regul Integr Comp Physiol 2004;287: R1014-R1030.
21. Rubanyi GM, Vanhoutte PM. Oxygen-derived free radicals, endothelium, and responsiveness of vascular smooth muscle. Am J Physiol 1986;250:H815-H821.
22. Ono T, Tsuruta R, Fujita M, Aki HS, Kutsuna S, Kawamura Y, Wakatsuki J, Aoki T, Kobayashi C, Kasaoka S, Maruyama I, Yuasa M, Maekawa T. Xanthine oxidase is one of the major sources of superoxide anion radicals in blood after reperfusion in rats with forebrain ischemia/reperfusion. Brain Res 2009;1305:158-167.
23. Bouchama A, Hammami MM, Haq A, Jackson J, al-Sedairy S. Evidence for endothelial cell activation/injury in heatstroke. Crit Care Med 1996;24:1173-1178.
24. Ten Cate H, Schoenmakers SH, Franco R, Timmerman JJ, Groot AP, Spek CA, Reitsma PH. Microvascular coagulopathy and disseminated intravascular coagulation. Crit Care Med 2001;29:S95-S98.
25. Tang D, Shi Y, Kang R, Li T, Xiao W, Wang H, Xiao X. Hydrogen peroxide stimulates macrophages and monocytes to actively release HMGB1. J Leukoc Biol 2007;81:741-747.
26. Tsung A, Klune JR, Zhang X, Jeyabalan G, Cao Z, Peng X, Stolz DB, Geller DA, Rosengart MR, Billiar TR. HMGB1 release induced by liver ischemia involves Toll-like receptor 4 dependent reactive oxygen species production and calcium-mediated signaling. J Exp Med 2007;204: 2913-2923.
27. Fan J, Li Y, Levy RM, Fan JJ, Hackam DJ, Vodovotz Y, Yang H, Tracey KJ, Billiar TR, Wilson MA. Hemorrhagic shock induces NAD(P)H oxidase activation in neutrophils: role of HMGB1-TLR4 signaling. J Immunol 2007;178: 6573-6580.
28. Bustin M. Regulation of DNA-dependent activities by the functional motifs of the high-mobility-group chromosomal proteins. Mol Cell Biol 1999;19:5237-5246.
29. Wang H, Bloom O, Zhang M, Vishnubhakat JM, Ombrellino M, Che J, Frazier A, Yang H, Ivanova S, Borovikova L, Manogue KR, Faist E, Abraham E, Andersson J, Andersson U, Molina PE, Abumrad NN, Sama A, Tracey KJ. HMG-1 as a late mediator of endotoxin lethality in mice. Science 1999;285: 248-251.
30. Qiu J, Nishimura M, Wang Y, Sims JR, Qiu S, Savitz SI, Salomone S, Moskowitz MA. Early release of HMGB-1 from neurons after the onset of brain ischemia. J Cereb Blood Flow Metab 2008;28:927-938.
31. Lotze MT, Tracey KJ. High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. Nat Rev Immunol 2005;5:331-342.
32. Wang H, Yang H, Tracey KJ. Extracellular role of HMGB1 in infl ammation and sepsis. J Intern Med 2004;255:320-331.
33. Koda Y, Tsuruta R, Fujita M, Miyauchi T, Kaneda K, Todani M, Aoki T, Shitara M, Izumi T, Kasaoka S, Yuasa M, Maekawa T. Moderate hypothermia suppresses jugular venous superoxide anion radical, oxidative stress, early infl ammation, and endothelial injury in forebrain ischemia/reperfusion rats. Brain Res 2010;1311:197-205.
34. Hamer I, Wattiaux R, Wattiaux-De Coninck S. Deleterious effects of xanthine oxidase on rat liver endothelial cells after ischemia/reperfusion. Biochim Biophys Acta 1995;1269: 145-152.
35. Maier CM, Sun GH, Cheng D, Yenari MA, Chan PH, Steinberg GK. Effects of mild hypothermia on superoxide anion production, superoxide dismutase expression, and activity following transient focal cerebral ischemia. Neurobiol Dis 2002;11:28-42.
36. Zar HA, Tanigawa K, Kim YM, Lancaster JR Jr. Mild therapeutic hypothermia for postischemic vasoconstriction in the perfused rat liver. Anesthesiology 1999;90:1103-1111.