Further stratification of risk groups in patients with lymph node metastasis after radical hysterectomy for early-stage cervical cancer

Gynecologic Oncology

Volumn 117, Issue 1, 2010, Pages 53-58

  Park, Jeong Yeol ^a   Kim, Dae Yeon ^a   Kim, Jong Hyeok ^a   Kim, Yong Man ^a   Kim, Young Tak ^a   Nam, Joo Hyun ^a  

^a University of Ulsan College of Medicine   (South Korea)

Author keywords

Adjuvant therapy; Early stage cervical cancer; Lymph node metastasis; Prognostic factor; Radical hysterectomy

Indexed keywords

ADULT; AGED; ARTICLE; CANCER ADJUVANT THERAPY; CANCER MORTALITY; CANCER RECURRENCE; CANCER RISK; CANCER SURGERY; CONTROLLED STUDY; EARLY CANCER; FEMALE; HIGH RISK POPULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; RADICAL HYSTERECTOMY; RETROSPECTIVE STUDY; RISK FACTOR; SCORING SYSTEM; TREATMENT FAILURE; TUMOR VOLUME; UTERINE CERVIX CANCER;

ADULT; AGED; AGED, 80 AND OVER; FEMALE; HUMANS; HYSTERECTOMY; LYMPH NODES; LYMPHATIC METASTASIS; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM STAGING; RISK FACTORS; UTERINE CERVICAL NEOPLASMS;

EID: 77949340403     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2009.12.006     Document Type: Article

References (33)

1. Waggoner S.E. Cervical cancer. Lancet 361 (2003) 2217-2225
2. Parkin D.M., Bray F.I., and Devesa S.S. Cancer burden in the year 2000. The global picture. Eur. J. Cancer 37 Suppl 8 (2001) S4-S66
3. Bray F., Carstensen B., Moller H., Zappa M., Zakelj M.P., Lawrence G., et al. Incidence trends of adenocarcinoma of the cervix in 13 European countries. Cancer Epidemiol. Biomarkers Prev. 14 (2005) 2191-2199
4. Peto J., Gilham C., Fletcher O., and Matthews F.E. The cervical cancer epidemic that screening has prevented in the UK. Lancet 364 (2004) 249-256
5. Landoni F., Maneo A., Colombo A., Placa F., Milani R., Perego P., et al. Randomised study of radical surgery versus radiotherapy for stage Ib-IIa cervical cancer. Lancet 350 (1997) 535-540
6. Hacker N.F. Cervical cancer. In: Berek J.S., and Hacker N.F. (Eds). Practical Gynecologic Oncology. 4th edition (2005), Lippincott Williams & Wilkins, Philadelphia, PA 337-396
7. Monaghan J.M., Ireland D., Mor-Yosef S., Pearson S.E., Lopes A., and Sinha D.P. Role of centralization of surgery in stage IB carcinoma of the cervix: a review of 498 cases. Gynecol. Oncol. 37 (1990) 206-209
8. Benedet J.L., Turko M., Boyes D.A., Nickerson K.G., and Bienkowska B.T. Radical hysterectomy in the treatment of cervical cancer. Am. J. Obstet. Gynecol. 137 (1980) 254-262
9. Lee Y.N., Wang K.L., Lin M.H., Liu C.H., Wang K.G., Lan C.C., et al. Radical hysterectomy with pelvic lymph node dissection for treatment of cervical cancer: a clinical review of 954 cases. Gynecol. Oncol. 32 (1989) 135-142
10. Ayhan A., and Tuncer Z.S. Radical hysterectomy with lymphadenectomy for treatment of early stage cervical cancer: clinical experience of 278 cases. J. Surg. Oncol. 47 (1991) 175-177
11. Averette H.E., Nguyen H.N., Donato D.M., Penalver M.A., Sevin B.U., Estape R., et al. Radical hysterectomy for invasive cervical cancer. A 25-year prospective experience with the Miami technique. Cancer 71 (1993) 1422-1437
12. Samlal R.A., van der Velden J., Schilthuis M.S., Gonzalez Gonzalez D., Ten Kate F.J., Hart A.A., et al. Identification of high-risk groups among node-positive patients with stage IB and IIA cervical carcinoma. Gynecol. Oncol. 64 (1997) 463-467
13. Lai C.H., Chang H.C., Chang T.C., Hsueh S., and Tang S.G. Prognostic factors and impacts of adjuvant therapy in early-stage cervical carcinoma with pelvic node metastases. Gynecol. Oncol. 51 (1993) 390-396
14. Alvarez R.D., Soong S.J., Kinney W.K., Reid G.C., Schray M.F., Podratz K.C., et al. Identification of prognostic factors and risk groups in patients found to have nodal metastasis at the time of radical hysterectomy for early-stage squamous carcinoma of the cervix. Gynecol. Oncol. 35 (1989) 130-135
15. Kodama J., Seki N., Ojima Y., Nakamura K., Hongo A., and Hiramatsu Y. Prognostic factors in node-positive patients with stage IB-IIB cervical cancer treated by radical hysterectomy and pelvic lymphadenectomy. Int. J. Gynaecol. Obstet. 93 (2006) 130-135
16. Fuller Jr. A.F., Elliott N., Kosloff C., and Lewis Jr. J.L. Lymph node metastases from carcinoma of the cervix, stages IB and IIA: implications for prognosis and treatment. Gynecol. Oncol. 13 (1982) 165-174
17. Kim S.M., Choi H.S., and Byun J.S. Overall 5-year survival rate and prognostic factors in patients with stage IB and IIA cervical cancer treated by radical hysterectomy and pelvic lymph node dissection. Int. J. Gynecol. Cancer 10 (2000) 305-312
18. Lahousen M., Haas J., Pickel H., Hackl A., Kurz C., Ogris H., et al. Chemotherapy versus radiotherapy versus observation for high-risk cervical carcinoma after radical hysterectomy: A randomized, prospective, multicenter trial. Gynecol. Oncol. 73 (1999) 196-201
19. Iwasaka T., Kamura T., Yokoyama M., Matsuo N., Nakano H., and Sugimori H. Adjuvant chemotherapy after radical hysterectomy for cervical carcinoma: a comparison with effects of adjuvant radiotherapy. Obstet. Gynecol. 91 (1998) 977-981
20. Lai C.H., Hong J.H., Hsueh S., Ng K.K., Chang T.C., Tseng C.J., et al. Preoperative prognostic variables and the impact of postoperative adjuvant therapy on the outcomes of stage IB or II cervical carcinoma patients with or without pelvic lymph node metastases: an analysis of 891 cases. Cancer 85 (1999) 1537-1546
21. Tattersall M.H., Ramirez C., and Coppleson M. A randomized trial of adjuvant chemotherapy after radical hysterectomy in stage Ib-IIa cervical cancer patients with pelvic lymph node metastases. Gynecol. Oncol. 46 (1992) 176-181
22. Nakanishi T., Ishikawa H., Suzuki Y., Inoue T., Nakamura S., and Kuzuya K. A comparison of prognoses of pathologic stage Ib adenocarcinoma and squamous cell carcinoma of the uterine cervix. Gynecol. Oncol. 79 (2000) 289-293
23. Monk B.J., Cha D.S., Walker J.L., Burger R.A., Ramsinghani N.S., Manetta A., et al. Extent of disease as an indication for pelvic radiation following radical hysterectomy and bilateral pelvic lymph node dissection in the treatment of stage IB and IIA cervical carcinoma. Gynecol. Oncol. 54 (1994) 4-9
24. Inoue T., and Morita K. The prognostic significance of number of positive nodes in cervical carcinoma stages IB, IIA, and IIB. Cancer 65 (1990) 1923-1927
25. Nahhas W.A., Sharkey F.E., Whitney C.W., Husseinzadeh N., Chung C.K., and Mortel R. The prognostic significance of vascular channel involvement and deep stromal penetration in early cervical carcinoma. Am. J. Clin. Oncol. 6 (1983) 259-264
26. Martimbeau P.W., Kjorstad K.E., Iversen T., and Stage I.B. carcinoma of the cervix, the Norwegian radium hospital. II. Results when pelvic nodes are involved. Obstet. Gynecol. 60 (1982) 215-218
27. Horn L.C., Hentschel B., Galle D., and Bilek K. Extracapsular extension of pelvic lymph node metastases is of prognostic value in carcinoma of the cervix uteri. Gynecol. Oncol. 108 (2008) 63-67
28. Hsu C.T., Cheng Y.S., and Su S.C. Prognosis of uterine cervical cancer with extensive lymph node metastases. Special emphasis on the value of pelvic lymphadenectomy in the surgical treatment of uterine cervical cancer. Am. J. Obstet. Gynecol. 114 (1972) 954-962
29. Morley G.W., and Seski J.C. Radical pelvic surgery versus radiation therapy for stage I carcinoma of the cervix (exclusive of microinvasion). Am. J. Obstet. Gynecol. 126 (1976) 785-798
30. Pilleron J.P., Durand J.C., and Hamelin J.P. Prognostic value of node metastasis in cancer of the uterine cervix. Am. J. Obstet. Gynecol. 119 (1974) 458-462
31. Piver M.S., and Chung W.S. Prognostic significance of cervical lesion size and pelvic node metastases in cervical carcinoma. Obstet. Gynecol. 46 (1975) 507-510
32. Tinga D.J., Timmer P.R., Bouma J., and Aalders J.G. Prognostic significance of single versus multiple lymph node metastases in cervical carcinoma stage IB. Gynecol. Oncol. 39 (1990) 175-180
33. Hale R.J., Buckley C.H., Fox H., Wilcox F.L., Tindall V.R., and Logue J.P. The morphology and distribution of lymph node metastases in stage IB/IIA cervical carcinoma: relationship to prognosis. Int. J. Gynecol. Cancer 1 (1991) 233-237