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Volumn 285, Issue 8, 2010, Pages 5888-5895
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Azadirachtin interacts with the Tumor Necrosis Factor (TNF) binding domain of its receptors and inhibits TNF-induced biological responses
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Author keywords
[No Author keywords available]
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Indexed keywords
ACTIVE COMPONENTS;
ADHESION MOLECULES;
ANTI-INFLAMMATORIES;
ANTI-INFLAMMATORY RESPONSE;
APOPTOSIS;
AZADIRACHTA INDICA;
AZADIRACHTIN;
BINDING DOMAIN;
BIOLOGICAL RESPONSE;
CELL SIGNALING;
CELL SURFACES;
CYCLOOXYGENASE 2;
DEATH DOMAIN;
DNA BINDING ACTIVITY;
DOWN-REGULATION;
EX-VIVO;
HUMAN CELL LINES;
IN-SILICO;
IN-VITRO;
MEDICINAL PLANTS;
NUCLEAR FACTORS;
NUCLEAR TRANSLOCATIONS;
TRANSFECTED CELLS;
TUMOR NECROSIS FACTORS;
BINDING ENERGY;
CELL CULTURE;
CELL DEATH;
CELL MEMBRANES;
PHOSPHORYLATION;
GENE EXPRESSION;
AZADIRACHTIN;
CELL ADHESION MOLECULE;
CYCLOOXYGENASE 2;
I KAPPA B KINASE;
IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;
INTERLEUKIN 1;
INTERLEUKIN 4;
INTERLEUKIN 8;
TRANSCRIPTION FACTOR RELA;
TUMOR NECROSIS FACTOR;
TUMOR NECROSIS FACTOR RECEPTOR;
TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED DEATH DOMAIN PROTEIN;
TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2;
TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;
ANTIINFLAMMATORY AGENT;
CYTOKINE;
INSECTICIDE;
LIMONOID;
PTGS2 PROTEIN, HUMAN;
RELA PROTEIN, HUMAN;
TNFSF10 PROTEIN, HUMAN;
TUMOR NECROSIS FACTOR ALPHA;
ANTIINFLAMMATORY ACTIVITY;
ARTICLE;
BINDING SITE;
CONTROLLED STUDY;
DRUG PROTEIN BINDING;
DRUG RECEPTOR BINDING;
DRUG RESPONSE;
ENZYME ACTIVITY;
ENZYME INHIBITION;
HUMAN;
HUMAN CELL;
PRIORITY JOURNAL;
PROTEIN DEGRADATION;
PROTEIN DOMAIN;
PROTEIN EXPRESSION;
PROTEIN PHOSPHORYLATION;
ACTIVE TRANSPORT;
CELL NUCLEUS;
CELL STRAIN U937;
DRUG ANTAGONISM;
DRUG EFFECT;
GENE EXPRESSION REGULATION;
HELA CELL;
METABOLISM;
PHOSPHORYLATION;
PROTEIN TERTIARY STRUCTURE;
AZADIRACHTA INDICA;
ACTIVE TRANSPORT, CELL NUCLEUS;
ANTI-INFLAMMATORY AGENTS;
BINDING SITES;
CELL NUCLEUS;
CYCLOOXYGENASE 2;
CYTOKINES;
GENE EXPRESSION REGULATION;
HELA CELLS;
HUMANS;
I-KAPPA B KINASE;
INSECTICIDES;
LIMONINS;
PHOSPHORYLATION;
PROTEIN STRUCTURE, TERTIARY;
RECEPTORS, TUMOR NECROSIS FACTOR;
TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN;
TNF RECEPTOR-ASSOCIATED FACTOR 2;
TNF-RELATED APOPTOSIS-INDUCING LIGAND;
TRANSCRIPTION FACTOR RELA;
TUMOR NECROSIS FACTOR-ALPHA;
U937 CELLS;
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EID: 77949324917
PISSN: 00219258
EISSN: 1083351X
Source Type: Journal
DOI: 10.1074/jbc.M109.065847 Document Type: Article |
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Times cited : (39)
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References (25)
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