Regulation of Vascular Endothelial Growth Factor (VEGF) splicing from pro-angiogenic to anti-angiogenic isoforms: A novel therapeutic strategy for angiogenesis

Journal of Biological Chemistry

Volumn 285, Issue 8, 2010, Pages 5532-5540

  Nowak, Dawid G ^a   Amin, Elianna Mohamed ^b   Rennel, Emma S ^a   Hoareau Aveilla, Coralie ^a   Gammons, Melissa ^a   Damodoran, Gopinath ^a   Hagiwara, Masatoshi ^c   Harper, Steven J ^a   Woolard, Jeanette ^a   Ladomery, Michael R ^b   Bates, David O ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF THE WEST OF ENGLAND   (United Kingdom)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALTERNATIVE SPLICING; ANGIOGENESIS; DOWN-REGULATION; EPITHELIAL CELLS; IMMUNOPRECIPITATIONS; IN-VIVO; INSULIN-LIKE GROWTH FACTOR-1; ISOFORMS; MOUSE MODELS; NEOVASCULARIZATION; NUCLEAR LOCALIZATION; NUCLEOTIDE SEQUENCES; PROTEIN KINASE C; RNA BINDING; SPLICE SITE; SR PROTEIN; THERAPEUTIC STRATEGY; VASCULAR ENDOTHELIAL GROWTH FACTOR;

BIOACTIVITY; CELLS; PEPTIDES; PHOSPHORYLATION; RNA; SELF ASSEMBLY;

SITE SELECTION;

ISOPROTEIN; MESSENGER RNA; PROTEIN KINASE; PROTEIN KINASE C; SOMATOMEDIN C; SR PROTEIN KINASE 1; SR PROTEIN KINASE 2; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN 165; ANGIOGENESIS INHIBITOR; ENZYME INHIBITOR; INSULIN LIKE GROWTH FACTOR 1, MOUSE; INSULIN-LIKE GROWTH FACTOR-1, MOUSE; NUCLEAR PROTEIN; PROTEIN SERINE THREONINE KINASE; SFRS1 PROTEIN, HUMAN; SRPK1 PROTEIN, HUMAN; SRPK1 PROTEIN, MOUSE; SRPK2 PROTEIN, HUMAN; SRPK2 PROTEIN, MOUSE; VASCULAR ENDOTHELIAL GROWTH FACTOR A, MOUSE; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; ENZYME BINDING; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RETINA NEOVASCULARIZATION; RNA SEQUENCE; RNA SPLICING; ALTERNATIVE RNA SPLICING; ANIMAL; BIOSYNTHESIS; CELL LINE; DISEASE MODEL; DRUG ANTAGONISM; GENETICS; METABOLISM; MOUSE;

ALTERNATIVE SPLICING; ANGIOGENESIS INHIBITORS; ANIMALS; CELL LINE, TRANSFORMED; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MICE; NUCLEAR PROTEINS; PROTEIN ISOFORMS; PROTEIN-SERINE-THREONINE KINASES; RETINAL NEOVASCULARIZATION; RNA, MESSENGER; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 77949318969     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.074930     Document Type: Article

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