High-dose cyclophosphamide-mediated anti-tumor effects by the superior expansion of CD44high cells after their selective depletion

Immunobiology

Volumn 215, Issue 3, 2010, Pages 182-193

  Hong, So Hee ^a   Yoon, Il Hee ^a   Kim, Yong Hee ^a   Yang, Seung Ha ^a   Park, Min Jung ^a   Nam, Hye Young ^a   Kim, Bongi ^a   Kim, Youngji ^b   Park, Chan Sik ^b   Park, Chung Gyu ^a  

^a Seoul National University College of Medicine   (South Korea)

^b University of Ulsan College of Medicine   (South Korea)

Author keywords

Anti tumor effects; Cyclophosphamide; IL 15 IL 15R; Memory T cell; Regulatory T cell

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CYCLOPHOSPHAMIDE; HERMES ANTIGEN; INTERLEUKIN 15; INTERLEUKIN 2 RECEPTOR ALPHA; MESSENGER RNA; TRANSCRIPTION FACTOR FOXP3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL COMPARTMENTALIZATION; CELL EXPANSION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG MECHANISM; DRUG MEGADOSE; FEMALE; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; IMMUNOCOMPETENCE; IMMUNOMODULATION; MELANOMA; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR UPREGULATION; REGULATORY T LYMPHOCYTE; SURVIVAL RATE; T CELL DEPLETION; TUMOR IMMUNITY;

ANIMALS; ANTIGENS, CD44; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL SEPARATION; CYCLOPHOSPHAMIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; IMMUNOLOGIC MEMORY; INTERLEUKIN-15; LYMPHOCYTE DEPLETION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, INTERLEUKIN-15; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY; UP-REGULATION;

EID: 77949271592     PISSN: 01712985     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imbio.2009.01.010     Document Type: Article

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