The acrosomal protein Dickkopf-like 1 (DKKL1) facilitates sperm penetration of the zona pellucida

Fertility and Sterility

Volumn 93, Issue 5, 2010, Pages 1533-1537

  Kohn, Matthew J ^a   Sztein, Jorge ^b   Yagi, Rieko ^a   DePamphilis, Melvin L ^a   Kaneko, Kotaro J ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b NATIONAL EYE INSTITUTE   (United States)

Author keywords

acrosome; DKKL1; Fertilization; IVF; sperm; zona pellucida

Indexed keywords

DICKKOPF 1 PROTEIN; RNA;

129 MOUSE; ANIMAL EXPERIMENT; ARTICLE; C57BL 6 MOUSE; CELL VIABILITY; EGG; EMBRYO; EMBRYO DEVELOPMENT; EXPERIMENTAL STUDY; FEMALE; FERTILITY; FERTILIZATION IN VITRO; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; INFERTILITY; MALE; MOUSE; NONHUMAN; NORTHERN BLOTTING; PREIMPLANTATION EMBRYO; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN EXPRESSION; REPRODUCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPERMATOCYTE; SPERMATOZOON MATURATION; SPERMATOZOON PENETRATION; TRANSGENIC MOUSE; WILD TYPE; ZONA PELLUCIDA;

ACROSOME; ANIMALS; BLASTOCYST; BLOTTING, NORTHERN; CELL LINEAGE; FEMALE; FERTILITY; FERTILIZATION IN VITRO; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTAGENESIS, SITE-DIRECTED; MUTATION; NUCLEAR PROTEINS; PLACENTA; PREGNANCY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA-BINDING PROTEINS; SPERM-OVUM INTERACTIONS; ZONA PELLUCIDA;

EID: 77949269062     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2009.06.010     Document Type: Article

References (37)

1. Niehrs C. Function and biological roles of the Dickkopf family of Wnt modulators. Oncogene 25 (2006) 7469-7481
2. Kaneko K.J., Kohn M.J., Liu C., and DePamphilis M.L. The acrosomal protein Dickkopf-Like 1 (Dkkl1) is not essential for fertility. Fertil Steril (2009) this issue
3. Sztein J.M., Farley J.S., and Mobraaten L.E. In vitro fertilization with cryopreserved inbred mouse sperm. Biol Reprod 63 (2000) 1774-1780
4. DePamphilis M.L., Herman S.A., Martinez-Salas E., Chalifour L.E., Wirak D.O., Cupo D.Y., et al. Microinjecting DNA into mouse ova to study DNA replication and gene expression and to produce transgenic animals. BioTechniques 6 (1988) 662-680
5. Kaneko K.J., Rein T., Guo Z.S., Latham K., and DePamphilis M.L. DNA methylation may restrict but does not determine differential gene expression at the Sgy/Tead2 locus during mouse development. Mol Cell Biol 24 (2004) 1968-1982
6. Cross J.C. How to make a placenta: mechanisms of trophoblast cell differentiation in mice-a review. Placenta 26 Suppl A (2005) S3-S9
7. Kunath T., Strumpf D., and Rossant J. Early trophoblast determination and stem cell maintenance in the mouse-a review. Placenta 25 Suppl A (2004) S32-S38
8. Smith A.G., Heath J.K., Donaldson D.D., Wong G.G., Moreau J., Stahl M., et al. Inhibition of pluripotential embryonic stem cell differentiation by purified polypeptides. Nature 336 (1988) 688-690
9. Williams R.L., Hilton D.J., Pease S., Willson T.A., Stewart C.L., Gearing D.P., et al. Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells. Nature 336 (1988) 684-687
10. Kaneko K.J., and DePamphilis M.L. Soggy, a spermatocyte-specific gene, lies 3.8 kb upstream of and antipodal to TEAD-2, a transcription factor expressed at the beginning of mouse development. Nucleic Acids Res 28 (2000) 3982-3990
11. Wassarman P.M., and Litscher E.S. Mammalian fertilization is dependent on multiple membrane fusion events. Methods Mol Biol 475 (2008) 99-113
12. Wassarman P.M., and Litscher E.S. Mammalian fertilization: the egg's multifunctional zona pellucida. Int J Dev Biol 52 (2008) 665-676
13. Nagy A., Gertsenstein M., Vintersten K., and Behringer R. Manipulating the mouse embryo: a laboratory manual. 3rd ed. (2003), Cold Spring Harbor Press, Cold Spring Harbor, NY
14. Dakhova O., O'Day D., Kinet N., Yucer N., Wiese M., Shetty G., et al. Dkkl1 regulates post-pubertal spermatocyte apoptosis and testosterone production. Endocrinology 150 (2009) 404-412
15. Rashel M., Uchiyama J., Takemura I., Hoshiba H., Ujihara T., Takatsuji H., et al. Tail-associated structural protein gp61 of Staphylococcus aureus phage phi MR11 has bifunctional lytic activity. FEMS Microbiol Lett 284 (2008) 9-16
16. Boerke A., Tsai P.S., Garcia-Gil N., Brewis I.A., and Gadella B.M. Capacitation-dependent reorganization of microdomains in the apical sperm head plasma membrane: functional relationship with zona binding and the zona-induced acrosome reaction. Theriogenology 70 (2008) 1188-1196
17. Evans J.P., and Florman H.M. The state of the union: the cell biology of fertilization. Nat Cell Biol 4 Suppl (2002) s57-s63
18. de Lamirande E., Leclerc P., and Gagnon C. Capacitation as a regulatory event that primes spermatozoa for the acrosome reaction and fertilization. Mol Hum Reprod 3 (1997) 175-194
19. Yanagimachi R. Mammalian fertilization. In: Knobil E., and Neill J. (Eds). The physiology of reproduction (1994), Raven Press, New York 189-317
20. Pizzari T. Of mice and sperm. Proc Natl Acad Sci USA 103 (2006) 14983-14984
21. Cummins J., and Yanagimachi R. Development of ability to penetrate the cumulus oophorus by hamster spermatozoa capacitated in vitro in relation to the timing of the acrosome reaction. Gamete Res 15 (1986) 187-212
22. Sutton K.A., Jungnickel M.K., and Florman H.M. A polycystin-1 controls postcopulatory reproductive selection in mice. Proc Natl Acad Sci USA 105 (2008) 8661-8666
23. Nayernia K., Drabent B., Meinhardt A., Adham I.M., Schwandt I., Muller C., et al. Triple knockouts reveal gene interactions affecting fertility of male mice. Mol Reprod Dev 70 (2005) 406-416
24. Adham I.M., Nayernia K., and Engel W. Spermatozoa lacking acrosin protein show delayed fertilization. Mol Reprod Dev 46 (1997) 370-376
25. Baba D., Kashiwabara S., Honda A., Yamagata K., Wu Q., Ikawa M., et al. Mouse sperm lacking cell surface hyaluronidase PH-20 can pass through the layer of cumulus cells and fertilize the egg. J Biol Chem 277 (2002) 30310-30314
26. Baba T., Azuma S., Kashiwabara S., and Toyoda Y. Sperm from mice carrying a targeted mutation of the acrosin gene can penetrate the oocyte zona pellucida and effect fertilization. J Biol Chem 269 (1994) 31845-31849
27. Lu Q., and Shur B.D. Sperm from beta 1,4-galactosyltransferase-null mice are refractory to ZP3-induced acrosome reactions and penetrate the zona pellucida poorly. Development 124 (1997) 4121-4131
28. Kim E., Baba D., Kimura M., Yamashita M., Kashiwabara S., and Baba T. Identification of a hyaluronidase, Hyal5, involved in penetration of mouse sperm through cumulus mass. Proc Natl Acad Sci USA 102 (2005) 18028-18033
29. Nayernia K., Drabent B., Adham I.M., Moschner M., Wolf S., Meinhardt A., et al. Male mice lacking three germ cell expressed genes are fertile. Biol Reprod 69 (2003) 1973-1978
30. Nayernia K., Adham I.M., Burkhardt-Gottges E., Neesen J., Rieche M., Wolf S., et al. Asthenozoospermia in mice with targeted deletion of the sperm mitochondrion-associated cysteine-rich protein (Smcp) gene. Mol Cell Biol 22 (2002) 3046-3052
31. Pearse II R.V., Drolet D.W., Kalla K.A., Hooshmand F., Bermingham Jr. J.R., and Rosenfeld M.G. Reduced fertility in mice deficient for the POU protein sperm-1. Proc Natl Acad Sci USA 94 (1997) 7555-7560
32. Roy A., Lin Y.N., Agno J.E., DeMayo F.J., and Matzuk M.M. Absence of tektin 4 causes asthenozoospermia and subfertility in male mice. FASEB J 21 (2007) 1013-1025
33. Gomendio M., Martin-Coello J., Crespo C., Magana C., and Roldan E.R. Sperm competition enhances functional capacity of mammalian spermatozoa. Proc Natl Acad Sci USA 103 (2006) 15113-15117
34. Agarwal A., Gupta S., and Sharma R.K. Role of oxidative stress in female reproduction. Reprod Biol Endocrinol 3 (2005) 28
35. Loret De Mola J.R., Garside W.T., Bucci J., Tureck R.W., and Heyner S. Analysis of the human zona pellucida during culture: correlation with diagnosis and the preovulatory hormonal environment. J Assist Reprod Genet 14 (1997) 332-336
36. Kaneko K.J., Cullinan E.B., Latham K.E., and DePamphilis M.L. Transcription factor mTEAD-2 is selectively expressed at the beginning of zygotic gene expression in the mouse. Development 124 (1997) 1963-1973
37. Yagi R., Kohn M.J., Karavanova I., Kaneko K.J., Vullhorst D., DePamphilis M.L., et al. Transcription factor TEAD4 specifies the trophectoderm lineage at the beginning of mammalian development. Development 134 (2007) 3827-3836