Lamivudine and adefovir resistance in children and young adults with chronic hepatitis B

International Journal of Infectious Diseases

Volumn 14, Issue 3, 2010, Pages

  Akman, Sezin Asik ^a   Kose, Sukran ^a   Halicioglu, Oya ^a  

^a MINISTRY OF HEALTH   (Turkey)

Author keywords

Adefovir; Hepatitis B; Lamivudine; Resistance

Indexed keywords

ADEFOVIR; ADEFOVIR DIPIVOXIL; ALANINE AMINOTRANSFERASE; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIGEN; LAMIVUDINE; RECOMBINANT ALPHA2B INTERFERON; VIRUS DNA;

ADOLESCENT; ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANTIGEN DETECTION; ANTIVIRAL RESISTANCE; ANTIVIRAL THERAPY; ARTICLE; CHILD; CHRONIC HEPATITIS; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG RESPONSE; FEMALE; HEPATITIS B; HUMAN; LONG TERM CARE; MALE; MUTATIONAL ANALYSIS; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; SCHOOL CHILD; TREATMENT DURATION; VIRUS LOAD; VIRUS MUTATION;

ADENINE; ADOLESCENT; ANTIVIRAL AGENTS; CHILD; DRUG ADMINISTRATION SCHEDULE; DRUG RESISTANCE, VIRAL; FEMALE; GENOTYPE; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; LAMIVUDINE; MALE; MUTATION; PHOSPHONIC ACIDS; REVERSE TRANSCRIPTASE INHIBITORS; TIME FACTORS; YOUNG ADULT;

EID: 77949267715     PISSN: 12019712     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijid.2009.04.002     Document Type: Article

References (26)

1. Baumert T.F., Thimme R., and von Weizsacker F. Pathogenesis of hepatitis B virus infection. World J Gastroenterol 13 (2007) 82-90
2. Chang M.H., and Hepatitis. B virus mutation in children. Indian J Pediatr 73 (2006) 803-807
3. Jonas M.M., Kelly D., Pollack H., Mizerski J., Sorbel J., Frederick D., et al. Safety, efficacy, and pharmacokinetics of adefovir dipivoxil in children and adolescents (age 2 to <18 years) with chronic hepatitis B. Hepatology 47 (2008) 1863-1871
4. Jonas M.M., Little N.R., Gardner S.D., and International Pediatric Lamivudine Investigator Group. Long-term lamivudine treatment of children with chronic hepatitis B: durability of therapeutic responses and safety. J Viral Hepat 15 (2008) 20-27
5. Suzuki F., Tsubota A., Arase Y., Suzuki Y., Akuta N., Hosaka T., et al. Efficacy of lamivudine therapy and factors associated with emergence of resistance in chronic hepatitis B virus infection in Japan. Intervirology 46 (2003) 182-189
6. Xu X.W., and Chen Y.G. Current therapy with nucleoside/nucleotide analogs for patients with chronic hepatitis B. Hepatobiliary Pancreat Dis Int 5 (2006) 350-359
7. Sokal E. Drug treatment of pediatric chronic hepatitis B. Paediatr Drugs 4 (2002) 361-369
8. Jonas M.M., Kelly D.A., Mizerski J., Badia I.B., Areias J.A., Schwarz K.B., et al. Clinical trial of lamivudine in children with chronic hepatitis B. N Engl J Med 346 (2002) 1706-1713
9. Heller S., and Valencia-Mayoral P. Treatment of viral hepatitis in children. Arch Med Res 38 (2007) 702-710
10. Fung S.K., and Fontana R.J. Management of drug-resistant chronic hepatitis B. Clin Liver Dis 10 (2006) 275-302
11. Delaney W.E., Locarnini S., and Shaw T. Resistance of hepatitis B virus to antiviral drugs: current aspects and directions for future investigation. Antivir Chem Chemother 12 (2001) 1-35
12. Lok A.S., Zoulim F., Locarnini S., Bartholomeusz A., Ghany M.G., Pawlotsky J.M., et al., Hepatitis B Virus Drug Resistance Working Group. Antiviral drug-resistant HBV: standardization of nomenclature and assays and recommendations for management. Hepatology 46 (2007) 254-265
13. Han S.H. Natural course, therapeutic options and economic evaluation of therapies for chronic hepatitis B. Drugs 66 (2006) 1831-1851
14. Knodell R.G., Ishak K.G., Black W.C., Chen T.S., Craig R., Kaplowitz N., et al. Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology 1 (1981) 431-435
15. Kowalik-Mikolajewska B., and Aniszewska M. [Lamivudine treatment of chronic hepatitis B in children after treatment with interferon alfa-evaluation of the effectiveness of prolonged therapy.]. Med Wieku Rozwoj 8 4 Pt 1 (2004) 901-910
16. Ni Y.H., Huang F.C., Wu T.C., Kong M.S., Jeng Y.M., Chen P.J., et al. Lamivudine treatment in maternally transmitted chronic hepatitis B virus infection patients. Pediatr Int 47 (2005) 372-377
17. Yao G.B., Cui Z.Y., Wang B.E., Yao J.L., and Zeng M.D. A 3-year clinical trial of lamivudine in treatment of patients with chronic hepatitis B. Hepatobiliary Pancreat Dis Int 3 (2004) 188-193
18. Peters M.G., Hann Hw H., Martin P., Heathcote E.J., Buggisch P., Rubin R., et al. Adefovir dipivoxil alone or in combination with lamivudine in patients with lamivudine-resistant chronic hepatitis B. Gastroenterology 126 (2004) 91-101
19. Lampertico P., Viganò M., Manenti E., Iavarone M., Sablon E., and Colombo M. Low resistance to adefovir combined with lamivudine. A 3-year study of 145 lamivudine-resistant hepatitis B patients. Gastroenterology 133 (2007) 1445-1451
20. Chen C.H., Wang J.H., Lee C.M., Hung C.H., Hu T.H., Wang J.C., et al. Virological response and incidence of adefovir resistance in lamivudine-resistant patients treated with adefovir dipivoxil. Antivir Ther 11 (2006) 771-778
21. Bozdayi A.M., Eyigun C.P., Turkyilmaz A.R., Avci I.Y., Pahsa A., and Yurdaydin C. A novel pattern (sW195a) in surface gene of HBV DNA due to YSDD (L180 M plus M204S) mutation selected during lamivudine therapy and successful treatment with adefovir dipivoxil. J Clin Virol 31 (2004) 76-77
22. Melegari M., Scaglioni P.P., and Wands J.R. Hepatitis B virus mutants associated with 3TC and famciclovir administration are replication defective. Hepatology 27 (1998) 628-633
23. Tunçbilek S., Köse S., Elaldi A., and Akman S. Lamivudine resistance in untreated chronic hepatitis B patients in Turkey. Turk J Gastroenterol 19 (2008) 99-103
24. Sun J., Wang Z., Ma S., Zeng G., Zhou Z., Luo K., et al. Clinical and virological characteristics of lamivudine resistance in chronic hepatitis B patients: a single center experience. J Med Virol 75 (2005) 391-398
25. Villet S., Pichoud C., Billioud G., Barraud L., Durantel S., Trépo C., et al. Impact of hepatitis B virus rtA181 V/T mutants on hepatitis B treatment failure. J Hepatol 48 (2008) 747-755
26. Gaia S., Barbon V., Smedile A., Olivero A., Carenzi S., Lagget M., et al. Lamivudine-resistant chronic hepatitis B: an observational study on adefovir in monotherapy or in combination with lamivudine. J Hepatol 48 (2008) 540-547