Anti-inflammatory effect of an ethanolic root extract of Heliopsis longipes in vitro

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas

Volumn 8, Issue 3, 2009, Pages 160-164

  Hernández, Ivones ^a   Lemus, Yeny ^a   Prieto, Sylvia ^a   Molina Torres, Jorge ^b   Garrido, Gabino ^a,c  

^a Centro de Quimica Farmaceutica   (Cuba)

^b DEPARTAMENTO DE FÍSICA   (Mexico)

^c UNIVERSIDAD CATÓLICA DEL NORTE   (Chile)

Author keywords

Heliopsis longipes; Inflammation; Macrophages; Nitric oxide; Tumor necrosis factor alpha

Indexed keywords

HELIOPSIS LONGIPES EXTRACT; NITRIC OXIDE; PLANT EXTRACT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; HELIOPSIS LONGIPES; IN VITRO STUDY; MEDICINAL PLANT; MEXICO; NONHUMAN; PLANT ROOT; TRADITIONAL MEDICINE;

ASTERACEAE; HELIOPSIS LONGIPES;

EID: 77749345760     PISSN: None     EISSN: 07177917     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Colvard MD, Cordell GA, Villalobos R, Sancho G, Soejarto DD, Pestle W, Lobo TE, Perkowitz KM, Michel J. 2006. Survey of medical ethnobotanicals for dental and oral medicine conditions and pathologies. J Ethnopharmacol 107:134-142
2. Delgado R, Carlin A, Airaghi L, Demitri MT, Meda L, Galimberti D, Baron P, Lipton JM, Catania A. 1998. Melanocortin peptides inhibit production of proinflammatory cytokines and nitric oxide by activated microglia. J Leukoc Biol 63:740-745.
3. Gomez-Flores R, Tucker S, Kansal R, Tamez-Guerra R, Mehta R. 1997. Enhancement of antibacterial activity of clofazimine against Mycobacterium avium-M. intracellulare complex infection induced by IFNγ is mediated by TNFα. J Antimicrob Chemother 39:189-197.
4. Gutiérrez-Lugo M, Barrientos-Benitez T, Luna B, Ramirez-Gama R, Bye R, Linares E, Mata R. 1996. Antimicrobial and cytotoxic activities of some crude drug extracts from Mexican Medicinal Plants. Phytomedicine 2:341-347.
5. Jun CD, Choi BM, Ryu H, Um JY, Kwak HJ, Lee BS, Paik SG, Kim HM, Chung HT. 1994. Synergistic cooperation between phorbol ester and IFNγ for induction of nitric oxide synthesis in murine peritoneal macrophages. J Immunol 153:3684-3690.
6. Macmicking J, Xie QW & Nathan C. 1997. Nitric oxide and macrophage function. Annu Rev Immunol 15:323-350.
7. Manthey JA, Grohmann K, Montanari A, Ash K, Manthey CL. 1999. Polymethoxylated flavones derived from citrus suppress tumor necrosis factor-alpha expression by human monocytes. J Nat Prod 62:441-444.
8. Matthias A, Banbury L, Stevenson LM, Bone KM, Leach DN, Lehmann RP. 2007. Alkylamides from Echinacea modulate induced immune responses in macrophages. Immunol Invest 36:117-130,
9. Molina-Torres J, Salazar-Cabrera CJ, Armenta-Salinas CN and Ramírez-Chávez E. 2004. Fungistatic and bacteriostatic activities of alkamides from Heliopsis longipes roots: Affinin and reduced amides. J Agr Food Chem 52:4700-4704
10. Molina-Torres J, García-Chávez A. 2001. Alcamidas en plantas: distribución e importancia. Rev Av Perspect 20:377-387.
11. Molina-Torres J, García-Chávez A, Ramírez- Chávez E. 1999. Antimicrobial properties of alkamides present in flavouring plants traditionally used in Mesoamerica: affinin and capsaicin. J Ethnopharmacol 64:241-248.
12. Molina-Torres, J.; Salgado-Garciglia, R.; Ramírez-Chávez, E.; del-Rio, R. 1996. Purely olefinic alkamides in Heliopsis longipes and Acmella (Spilanthes) oppositifolia. Biochem Syst Ecol 24:43-47.
13. Müller-Jakic B. 1994. In vitro inhibition of cyclooxygenase and 5-lipoxygenase by alkamides from Echinacea and Achillea species. Planta Med 60:37-40.
14. Murakami A, Nakamura Y, Tanaka T, Kawabata K, Takahashi D, Koshimizu K, Ohigashi H. 2000. Suppression by citrus auraptene of phorbol ester-and endotoxin-induced inflammatory responses: role of attenuation of leukocyte activation. Carcinogenesis 21:1843-1850.
15. Ogura M, Cordell GA, Quinn ML, León C, Benoit PS, Soejarto DD, Farnsworth NR. 1982. Ethnomedical studies. I. Rapid solution to a problem-oral use of Heliopsis longipes by means of a multidisciplinary approach. J Ethnopharmacol 5:215-219.
16. Paul-Clark M, Gilroy D, Willis D, Willoughby D, Tomlinson A. 2001. Nitric oxide synthase Inhibitors have opposite effects on acute inflammation depending on their route of administration. J Immunol 166:1169-1177.
17. Raso GM, Pacilio M, Di Carlo G, Esposito E, Pinto L, Meli R. 2002. In-vivo and in-vitro anti-inflammatory effect of Echinacea purpurea and Hypericum perforatum. J Pharm Pharmacol 54:1379-1383.
18. Tragni E, Tubaro A, Melis S, Galli CL. 1985. Evidence from two classic irritation tests for an anti-inflammatory action of a natural extract, Echinacina B. Food Chem Toxicol 23:317-319.
19. Tubaro A, Tragni E, del Negro P, Galli CL, Della Loggia R. 1987. Anti-inflammatory activity of a polysaccharide fraction of Echinacea angustifolia. J Pharm Pharmacol 39:567-569
20. Vilcek J, Lee TH. 1991. Tumor necrosis factor. New insights into the molecular mechanisms of its multiple actions. J Biol Chem 266:7313-7316.