Preparative separation of alkaloids from Nelumbo nucifera Gaertn by pH-zone-refining counter-current chromatography

Journal of Separation Science

Volumn 33, Issue 4-5, 2010, Pages 539-544

  Wang, Xiao ^a   Liu, Jianhua ^a   Geng, Yanling ^a   Wang, Daijie ^a   Dong, Hongjing ^a   Zhang, Tianyou ^a  

^a QILU UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

Isoliensinine; Liensinine; Neferine; Nelumbo nucifera gaertn; pH zone refining counter current chromatography

Indexed keywords

AQUEOUS MOBILE PHASE; CRUDE EXTRACT; ETHYL ACETATES; METHANOL-WATER; N-HEXANE; NELUMBO NUCIFERA GAERTN; PH-ZONE-REFINING COUNTER-CURRENT CHROMATOGRAPHY; PREPARATIVE SEPARATION; STATIONARY PHASE; TRIETHYLAMINES; TWO-PHASE SOLVENT SYSTEM;

CHROMATOGRAPHY; ESTERS; HEXANE; METHANOL;

REFINING;

ACETIC ACID ETHYL ESTER; ALKALOID; ALKALOID DERIVATIVE; CHLORIDE; ISOLIENSININE; LIENSININE; NEFERINE; NELUMBO NUCIFERA EXTRACT; ORGANIC SOLVENT; SOLVENT; TRIETHYLAMINE; UNCLASSIFIED DRUG; WATER;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; COUNTER CURRENT CHROMATOGRAPHY; NELUMBO; NELUMBO NUCIFERA; NONHUMAN; PH ZONE REFINING COUNTER CURRENT CHROMATOGRAPHY; PHASE SEPARATION; PLANT SEED; PLANT YIELD; PRIORITY JOURNAL; SEPARATION TECHNIQUE;

ALKALOIDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COUNTERCURRENT DISTRIBUTION; HYDROGEN-ION CONCENTRATION; MOLECULAR STRUCTURE; NELUMBO; ORGANIC CHEMICALS; PLANT PREPARATIONS; SEEDS; SOLVENTS; WATER;

NELUMBO NUCIFERA;

EID: 77749341209     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.200900561     Document Type: Article

References (23)

1. Ito, Y., J. Chromatogr. 1981, 214, 122-125.
2. Zhang, T. Y., Preparation and Purification of Active Compounds from Natural Products (Chinese Herbs) by HSCCC, in: Berthod, A. (Ed.), Countercurrent Chromatography - The Support-Free Liquid Stationary Phase, Elsevier, Amsterdam 2002, pp. 201-260.
3. Weisz, A., Scher, A. L., Shinomiya, K., Fales, H. M., Ito, Y., J. Am. Chem. Soc. 1994, 116, 704-708.
4. Ito, Y., Ma, Y., J. Chromatogr. A 1996, 753, 1-36.
5. Toribio, A., Delannay, E., Richard, B., Ple, K., Zeches-Hanrot, M., Nuzillard, J. M., Renault, J. H., J. Chromatogr. A 2007, 1140, 101-106.
6. Ito, Y., J. Chromatogr. A 2005, 1065, 145-168.
7. Wang, J. L, Hu, X. M., Yin, W. H., China J. Chin. Mater. Med. 1991, 16, 673-675.
8. Yu, W. G ., Zhang, D. M., Liu, L., Huang, X. J., He, S. R., Deng, D. M., J. Yangtze Uni. 2006, 3, 213-214.
9. Wang, H., Zhou, L., Liu, G., Chin. Pharmacol. Bull. 2006, 22: 1088-1091.
10. Wang, J. L., Nong, Y., Xia, G. J., Yao, W. X., Acta Pharmacol. Sin. 1993, 28, 812-816.
11. Chen, Y., Fan, R. G., Wu, H., Wu, Y., Mitchell, A., J. Pharm. Biomed. Anal. 2007, 43, 99-104.
12. Wang, H., Sun, C. Y., Liu, G., Chin. J. Biochem. Pharm. 2005, 26, 21-23.
13. Tang, G. X., Zhao, L. B., Wang, X. M., Zhang, S. H., Wang, J. L., Chin. J. Pharmacol. Toxicol. 2007, 21, 462-469.
14. Hu, C. Y., Zeng, Q. T., Central Chin. Med. J. 2006, 30, 401-403.
15. Yu, J., Hu, W. S., Acta Univ. Med. Tongji. 1998, 27, 66-69.
16. Wu, Y. M., Jia, J. F., Li, Y. J., J. Chin. Pharmacol. Toxicol. 1997, 11, 27-30.
17. Shi, S. H., Zhang, H., Zhuang, Y. Z., Cao, J. G., Chin. Clin. Oncol. 2008, 13, 427-431.
18. Yang, Z. S., Qin, Q., Min, H., Long, L., Xiao, Y. H., Xiang, T., Central South Pharm. 2008, 6, 280-282.
19. Zhang, J. X., Guo, J. S., Yang, J. L., Ou, L. L., Ion Exchange Adsorp. 2008, 24, 512-517.
20. Lou, H. X., Yuan, H. Q., Ji, M., Xu, D. Y., Acta Academiae Medicinae Shandong 1995, 33, 346-348.
21. Wu, S., Sun, C., Cao, X., Zhou, H., Hong, Z., Pan, Y., J. Chromatogr. A 2004, 1041, 153-162.
22. Yuan, L.M., Chen, X. X., Ai, P., Qi, S. H., Li, B. F., Wang, D., J. Liq.Chromatogr. Relat. Technol. 2004, 27, 365-369.
23. Ma, Y., Ito, Y., Sokolosky, E., Fales, H. M., J. Chromatogr. A 1994, 685, 259-262.