Hydrazinopeptide motifs synthesized via the Ugi reaction: An insight into the secondary structure

Synthesis

Volumn , Issue 6, 2010, Pages 933-942

  Krasavin, Mikhail ^a   Bushkova, Ekaterina ^a   Parchinsky, Vladislav ^b   Shumsky, Alexei ^b  

^a YAROSLAVL STATE PEDAGOGICAL UNIVERSITY   (Russian Federation)

^b Chemical Diversity Research Institute   (Russian Federation)

Author keywords

Hydrazones; Multicomponent reactions; Peptidomimetics; Secondary structures; Substituent effects

Indexed keywords

HYDRAZONES; MULTI-COMPONENT REACTIONS; PEPTIDOMIMETICS; SECONDARY STRUCTURES; SUBSTITUENT EFFECT;

ALKYLATION; CARBOXYLIC ACIDS; CYANIDES; HYDROCARBONS; ORGANIC ACIDS;

SYNTHESIS (CHEMICAL);

2 (1 BUTYL 2 ISONICOTINOYLHYDRAZINO) N (2 METHOXYETHYL)PENTANAMIDE; 2 (2 ACETYLHYDRAZINO) 2 CYCLOHEXYL N (2 METHOXYBENZYL)ACETAMIDE; 2 (2 BENZOYLHYDRAZINO) 2 CYCLOHEXYL N (2 METHOXYETHYL)ACETAMIDE; 2 (2 ISONICOTINOYLHYDRAZINO) N (2 METHOXYETHYL)PENTANAMIDE; 2 [1 BUTYL 2 (PYRAZIN 2 YLCARBONYL)HYDRAZINO] 2 CYCLOHEXYL N (2 METHOXYETHYL)ACETAMIDE; 2 [2 ISONICOTINOYL 1 (3 METHYLBUTYL)HYDRAZINO] N (2 METHOXYETHYL)PENTANAMIDE; 2 CYCLOHEXYL 2 (2 ISONICOTINOYLHYDRAZINO) N (2 METHOXYETHYL)ACETAMIDE; 2 CYCLOHEXYL 2 [2 ISONICOTINOYL 1 (3 METHYLBUTYL)HYDRAZINO] N (2 METHOXYETHYL)ACETAMIDE; 2 CYCLOHEXYL N (2 METHOXYETHYL) 2 [1 (3 METHYLBUTYL) 2 [2 (4 TOLYL)ACETYL]HYDRAZINO]ACETAMIDE; 2 CYCLOHEXYL N (2 METHOXYETHYL) 2 [2 (PYRAZIN 2 YLCARBONYL)HYDRAZINO]ACETAMIDE; 2 CYCLOHEXYL N (2 METHOXYETHYL) 2 [2 [2 (4 TOLYL)ACETYL]HYDRAZINO]ACETAMIDE; CYANIDE; HYDRAZINE DERIVATIVE; METHYL 2 CYCLOHEXYL 2 [2 (PYRAZIN 2 YLCARBONYL)HYDRAZINO]ACETATE; N (TERT BUTYL) 2 [2 [2 (4 METHOXYPHENOXY)ACETYL] 1 (2,2,2 TRIFLUOROACETYL)HYDRAZINO] 4 METHYLPENTANAMIDE; N (TERT BUTYL) 2 [2 [2 (4 METHOXYPHENOXY)ACETYL]HYDRAZINO] 4 METHYLPENTANAMIDE; N BENZYL 2 (1 BUTYL 2 ISONICOTINOYLHYDRAZINO) 2 CYCLOHEXYLACETAMIDE; N BENZYL 2 (1 BUTYL 2 ISONICOTINOYLHYDRAZINO)PENTANAMIDE; N BENZYL 2 (2 ISONICOTINOYLHYDRAZINO)PENTANAMIDE; N BENZYL 2 [1 BUTYL 2 (PYRAZIN 2 YLCARBONYL)HYDRAZINO] 2 CYCLOHEXYLACETAMIDE; N BENZYL 2 [2 ISONICOTINOYL 1 (3 METHYLBUTYL)HYDRAZINO]PENTANAMIDE; N BENZYL 2 CYCLOHEXYL 2 (2 ISONICOTINOYLHYDRAZINO)ACETAMIDE; N BENZYL 2 CYCLOHEXYL 2 [1 (3 METHYLBUTYL) 2 (PYRAZIN 2 YLCARBONYL)HYDRAZINO]ACETAMIDE; N BENZYL 2 CYCLOHEXYL 2 [2 (PYRAZIN 2 YLCARBONYL)HYDRAZINO]ACETAMIDE; N CYCLOHEXYL 2 [2 [2 (4 TOLYL)ACETYL]HYDRAZINO]BUTANAMIDE; TERT BUTYL 2 [1 (TERT BUTYLCARBAMOYL) 2 METHYLPROPYL]HYDRAZINE 1 CARBOXYLATE; TERT BUTYL 2 [1 [(4 METHOXYBENZYL)CARBAMOYL] 2 METHYLPROPYL]HYDRAZINE 1 CARBOXYLATE; TRIFLUOROACETIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS; UGI REACTION; X RAY CRYSTALLOGRAPHY;

EID: 77749328043     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0029-1219274     Document Type: Article

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