Evaluation of cell proliferation rate in non-dysplastic leukoplakias

Medicina Oral, Patologia Oral y Cirugia Bucal

Volumn 15, Issue 2, 2010, Pages

  Hildebrand, Laura De Campos ^a   Carrard, Vinicius Coelho ^a   Lauxen, Isabel Da Silva ^a   De Quadros, Onofre Francisco ^a   Chaves, Anna Cecília Moraes ^a   Sant'Ana Filho, Manoel ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Acanthosis; AgNOR; Cell proliferation; Epithelial dysplasia; Hyperkeratosis; Leukoplakia

Indexed keywords

ARGYROPHILIC NUCLEOLAR ORGANIZER REGION PROTEIN; CELL PROTEIN; UNCLASSIFIED DRUG;

ACANTHOSIS; ADULT; ARTICLE; CELL NUCLEUS; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; HYPERKERATOSIS; LEUKOPLAKIA; MALE; MOUTH MUCOSA;

ANTIGENS, NUCLEAR; CELL PROLIFERATION; FEMALE; HUMANS; LEUKOPLAKIA, ORAL; MALE; MIDDLE AGED;

EID: 77749289162     PISSN: 16984447     EISSN: 16986946     Source Type: Journal    
DOI: 10.4317/medoral.15.e328     Document Type: Article

References (24)

1. Kramer IR, Lucas RB, Pindborg JJ, Sobin LH. Definition of leukoplakia and related lesions: an aid to studies on oral precancer. Oral Surg Oral Med Oral Pathol. 1978;46:518-39.
2. Waldron CA, Shafer WG. Leukoplakia revisited. A clinicopathologic study 3256 oral leukoplakias. Cancer. 1975;36:1386-92.
3. Van der Waal I. Potentially malignant disorders of the oral and oropharyngeal mucosa; terminology, classification and present concepts of management. Oral Oncol. 2009;45:317-23.
4. Xie X, Clausen OP, Sudbö J, Boysen M. Diagnostic and prognostic value of nucleolar organizer regions in normal epithelium, dysplasia, and squamous cell carcinoma of the oral cavity. Cancer. 1997;79:2200-8.
5. Sirri V, Urcuqui-Inchima S, Roussel P, Hernandez-Verdun D. Nucleolus: the fascinating nuclear body. Histochem Cell Biol. 2008;129:13-31.
6. Derenzini M, Treré D, Pession A, Govoni M, Sirri V, Chieco P. Nucleolar size indicates the rapidity of cell proliferation in cancer tissues. J Pathol. 2000;191:181-6.
7. Chimenos-Küstner E, Font-Costa I, López-López J. Oral cancer risk and molecular markers. Med Oral Patol Oral Cir Bucal. 2004;9:381-4; 377-80.
8. Liu SC, Sauter ER, Clapper ML, Feldman RS, Levin L, Chen SY, et al. Markers of cell proliferation in normal epithelia and dysplastic leukoplakias of the oral cavity. Cancer Epidemiol Biomarkers Prev. 1998;7:597-603.
9. Warnakulasuriya KA, Johnson NW. Nucleolar organiser region (NOR) distribution as a diagnostic marker in oral keratosis, dysplasia and squamous cell carcinoma. J Oral Pathol Med. 1993;22:77-81.
10. Pich A, Chiusa L, Margaria E. Prognostic relevance of AgNORs in tumor pathology. Micron. 2000;31:133-41.
11. Holmstrup P, Vedtofte P, Reibel J, Stoltze K. Long-term treatment outcome of oral premalignant lesions. Oral Oncol. 2006;42:461-74.
12. Schwarz S, Bier J, Driemel O, Reichert TE, Hauke S, Hartmann A, et al. Losses of 3p14 and 9p21 as shown by fluorescence in situ hybridization are early events in tumorigenesis of oral squamous cell carcinoma and already occur in simple keratosis. Cytometry A. 2008;73:305-11.
13. Warnakulasuriya S, Reibel J, Bouquot J, Dabelsteen E. Oral epithelial dysplasia classification systems: predictive value, utility, weaknesses and scope for improvement. J Oral Pathol Med. 2008;37:127-33.
14. Ploton D, Menager M, Jeannesson P, Himber G, Pigeon F, Adnet JJ. Improvement in the staining and in the visualization of the argyrophilic proteins of the nucleolar organizer region at the optical level. Histochem J. 1986;18:5-14.
15. Oliver RJ, MacDonald DG, Felix DH. Aspects of cell proliferation in oral epithelial dysplastic lesions. J Oral Pathol Med. 2000;29:49-55.
16. Crocker J, Boldy DA, Egan MJ. How should we count AgNORS? Proposals for a standardized approach. J Pathol. 1989;158:185-8.
17. Hsue SS, Wang WC, Chen CH, Lin CC, Chen YK, Lin LM. Malignant transformation in 1458 patients with potentially malignant oral mucosal disorders: a follow-up study based in a Taiwanese hospital. J Oral Pathol Med. 2007;36:25-9.
18. Johann AC, Da Silveira-Júnior JB, Souto GR, Horta MC, Aguiar MC, Mesquita RA. Metallothionein immunoexpression in oral leukoplakia. Med Oral Patol Oral Cir Bucal. 2008;13:E156-60.
19. Holmstrup P, Vedtofte P, Reibel J, Stoltze K. Oral premalignant lesions: is a biopsy reliable? J Oral Pathol Med. 2007;36:262-6.
20. Migaldi M, Criscuolo M, Zunarelli E, Lo Bianco L, Martinelli AM, Barbolini G. p120 and AgNOR nucleolar protein expression: a comparison with nuclear proliferation markers in oral pathology. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998;85:189-96.
21. Kaplan I, Engelberg J, Dayan D. The effect of desalivation on 4-nitroquinoline-1-oxide-induced tongue carcinogenesis: a morphometric study of nucleolar organizer regions. J Oral Pathol Med. 2001;30:48-52.
22. Chattopadhyay A, Ray JG. AgNOR cut-point to distinguish mild and moderate epithelial dysplasia. J Oral Pathol Med. 2008;37:78-82.
23. Shin DM, Kim J, Ro JY, Hittelman J, Roth JA, Hong WK, et al. Activation of p53 gene expression in premalignant lesions during head and neck tumorigenesis. Cancer Res. 1994;54:321-6.
24. Glickman JN, Yang A, Shahsafaei A, McKeon F, Odze RD. Expression of p53-related protein p63 in the gastrointestinal tract and in esophageal metaplastic and neoplastic disorders. Hum Pathol. 2001;32:1157-65.