Adiposity is inversely related to insulin sensitivity in relatively lean Chinese adolescents: A population-based twin study

American Journal of Clinical Nutrition

Volumn 91, Issue 3, 2010, Pages 662-671

  Ouyang, Fengxiu ^a   Christoffel, Katherine Kaufer ^a   Brickman, Wendy J ^b   Zimmerman, Donald ^b   Wang, Binyan ^a   Xing, Houxun ^c   Zhang, Shanchun ^a   Arguelles, Lester M ^a   Wang, Guoying ^d   Liu, Rong ^a   Xu, Xiping ^d   Wang, Xiaobin ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c ANHUI MEDICAL UNIVERSITY   (China)

^d UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN;

ADOLESCENT; ADULT; ANTHROPOMETRY; ARTICLE; BODY FAT; BODY MASS; CHINESE; COHORT ANALYSIS; CONTROLLED STUDY; ENVIRONMENTAL FACTOR; GROUPS BY AGE; HEREDITY; HOMEOSTASIS; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; LEAN BODY WEIGHT; MALE; NORMAL HUMAN; PHYSICAL ACTIVITY; POPULATION RESEARCH; RURAL POPULATION; SEX DIFFERENCE; TWINS; WAIST CIRCUMFERENCE; ZYGOSITY;

ADIPOSE TISSUE; ADIPOSITY; ADOLESCENT; ADULT; CHINA; DISEASES IN TWINS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INSULIN; INSULIN RESISTANCE; MALE; WAIST CIRCUMFERENCE; YOUNG ADULT;

EID: 77749279631     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.3945/ajcn.2009.28750     Document Type: Article

References (27)

1. Ebbeling CB, Pawlak DB, Ludwig DS. Childhood obesity: public-health crisis, common sense cure. Lancet 2002;360:473-82.
2. MacKay AP, Duran C. Adolescent health in the United States, 2007. Atlanta, GA: National Center for Health Statistics, 2007.
3. Fagot-Campagna A, Pettitt DJ, Engelgau MM, et al. Type 2 diabetes among North American children and adolescents: an epidemiologic review and a public health perspective. J Pediatr 2000;136:664-72.
4. Ji CY. The prevalence of childhood overweight/obesity and the epidemic changes in 1985-2000 for Chinese school-age children and adolescents. Obes Rev 2008;9(suppl 1):78-81.
5. Morrison JA, Barton BA, Biro FM, Daniels SR, Sprecher DL. Overweight, fat patterning, and cardiovascular disease risk factors in black and white boys. J Pediatr 1999;135:451-7.
6. Morrison JA, Sprecher DL, Barton BA, Waclawiw MA, Daniels SR. Overweight, fat patterning, and cardiovascular disease risk factors in black and white girls: the National Heart, Lung, and Blood Institute Growth and Health Study. J Pediatr 1999;135:458-64.
7. Cruz ML, Shaibi GQ, Weigensberg MJ, Spruijt-Metz D, Ball GD, Goran MI. Pediatric obesity and insulin resistance: chronic disease risk and implications for treatment and prevention beyond body weight modification. Annu Rev Nutr 2005;25:435-68.
8. Moran A, Jacobs DR Jr, Steinberger J, et al. Insulin resistance during puberty: results from clamp studies in 357 children. Diabetes 1999;48:2039-44.
9. Field AE, Cook NR, Gillman MW. Weight status in childhood as a predictor of becoming overweight or hypertensive in early adulthood. Obes Res 2005;13:163-9.
10. Shoelson SE, Lee J, Goldfine AB. Inflammation and insulin resistance. J Clin Invest 2006;116:1793-801.
11. Samaras K, Nguyen TV, Jenkins AB, et al. Clustering of insulin resistance, total and central abdominal fat: same genes or same environment? Twin Res 1999;2:218-25.
12. Zhang CX, Tse LA, Deng XQ, Jiang ZQ. Cardiovascular risk factors in overweight and obese Chinese children: a comparison of weight-for-height index and BMI as the screening criterion. Eur J Nutr 2008;47: 244-50.
13. Kong AP, Choi KC, Ko GT, et al. Associations of overweight with insulin resistance, beta-cell function and inflammatory markers in Chinese adolescents. Pediatr Diabetes 2008;9:488-95.
14. Ford ES, Li C, Imperatore G, Cook S. Age, sex, and ethnic variations in serum insulin concentrations among U.S. youth: findings from the National Health and Nutrition Examination Survey 1999-2002. Diabetes Care 2006;29:2605-11.
15. Ouyang F, Wang B, Arguelles LM, et al. Bone growth patterns in Chinese children and adolescents: a 6 year follow-up study provides evidence for sexual dimorphism and tracking. Arch Osteoporos 2007;2: 29-43.
16. Wang B, Necheles J, Ouyang F, et al. Monozygotic co-twin analyses of body composition measurements and serum lipids. Prev Med 2007;45: 358-65.
17. Yu Y, Lu BS, Wang B, et al. Short sleep duration and adiposity in Chinese adolescents. Sleep 2007;30:1688-97.
18. Poulsen P, Levin K, Beck-Nielsen H, Vaag A. Age-dependent impact of zygosity and birth weight on insulin secretion and insulin action in twins. Diabetologia 2002;45:1649-57.
19. Magee L. R2 measures based on Wald and likelihood ratio joint significance tests. Am Stat 1990;44:250-3.
20. Rijsdijk FV, Sham PC. Analytic approaches to twin data using structural equation models. Brief Bioinform 2002;3:119-33.
21. WHO. Growth reference 5-19 years. http://www.who.int/growthref/who2007- bmi-for-age/en/ (cited 25 May 2009).
22. Roemmich JN, Clark PA, Lusk M, et al. Pubertal alterations in growth and body composition. VI. Pubertal insulin resistance: relation to adiposity, body fat distribution and hormone release. Int J Obes Relat Metab Disord 2002;26:701-9.
23. Grant AM, Taungapeau FK, McAuley KA, et al. Body mass index status is effective in identifying metabolic syndrome components and insulin resistance in Pacific Island teenagers living in New Zealand. Metabolism 2008;57:511-6.
24. Lee S, Bacha F, Gungor N, Arslanian SA. Waist circumference is an independent predictor of insulin resistance in black and white youths. J Pediatr 2006;148:188-94.
25. Nelson TL, Vogler GP, Pedersen NL, Hong Y, Miles TP. Genetic and environmental influences on body fat distribution, fasting insulin levels and CVD: are the influences shared? Twin Res 2000;3:43-50.
26. Comuzzie AG, Blangero J, Mahaney MC, et al. Genetic and environmental correlations among hormone levels and measures of body fat accumulation and topography. J Clin Endocrinol Metab 1996;81: 597-600.
27. Monrad RN, Grunnet LG, Rasmussen EL, Malis C, Vaag A, Poulsen P. Age-dependent nongenetic influences of birth weight and adult body fat on insulin sensitivity in twins. J Clin Endocrinol Metab 2009;94: 2394-9.