Pericytes in the macrovascular intima: Possible physiological and pathogenetic impact

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 298, Issue 3, 2010, Pages

  Juchem, Gerd ^a   Weiss, Dominik R ^c   Gansera, Brigitte ^b   Kemkes, Bernhard M ^b   Mueller Hoecker, Josef ^a   Nees, Stephan ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b KLINIKUM BOGENHAUSEN   (Germany)

^c UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Atherosclerosis; Coronary bypass operation; Endothelium; Thrombosis; Tissue factor

Indexed keywords

BLOOD CLOTTING FACTOR; PROTEIN C; THROMBOMODULIN; THROMBOPLASTIN;

ARTICLE; ATHEROSCLEROTIC PLAQUE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; INCUBATION TIME; INTIMA; MACROVASCULAR INTIMA; PATHOGENESIS; PERICYTE; PRIORITY JOURNAL; RESTENOSIS; SUBENDOTHELIUM;

ANIMALS; CATTLE; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CELL SEPARATION; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; MODELS, ANIMAL; PERICYTES; SAPHENOUS VEIN; THROMBOPLASTIN; TUNICA INTIMA;

EID: 77749254638     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00343.2009     Document Type: Article

References (77)

1. Aikawa M, Libby P. The vulnerable atherosclerotic plaque: pathogenesis and therapeutic approach. Cardiovasc Pathol 13: 125-138, 2004.
2. Andreeva ER, Pugach IM, Gordon D, Orekhov AN. Continuous subendothelial network formed by pericyte-like cells in human vascular bed. Tissue Cell 30: 127-135, 1998.
3. Aojanepong C, Ozerdem OR, Losken HW. Shortening of mandibular linear distance with multivector distraction. J Craniomaxillofac Surg 12: 505-514, 2001.
4. Armulik A, Abramsson A, Betsholtz C. Endothelial/pericyte interactions. Circ Res 97: 512-523, 2005.
5. Bär T, Budi Santoso AW. Identification of pericytes in the central nervous system by silver staining of the basal lamina. Cell Tissue Res 236: 491-493, 1984.
6. Bergers G, Song S. The role of pericytes in blood-vessel formation and maintenance. Neuro Oncol 7: 452-464, 2005.
7. Bombeli T, Mueller M, Haeberli A. Anticoagulant properties of the vascular endothelium. Thromb Haemost 77: 408-423, 1997.
8. Bostrom K, Watson KE, Horn S, Wortham C, Herman IM, Demer LL. Bone morphogenetic protein expression in human atherosclerotic lesions. J Clin Invest 91: 1800-1809, 1993.
9. Bouchard BA, Shatos MA, Tracy PB. Human brain pericytes differentially regulate expression of procoagulant enzyme complexes comprising the extrinsic pathway of blood coagulation. Arterioscler Thromb Vasc Biol 17: 1-9, 1997.
10. Bourassa MG. Fate of venous grafts: the past, the present and the future. J Am Coll Cardiol 17: 1081-1083, 1991.
11. Butenas S, Bouchard BA, Brummel-Ziedins KE, Parhami-Seren B, Mann KG. Tissue factor activity in whole blood. Blood 105: 2764-2770, 2005.
12. Cai X. Regulation of smooth muscle cells in development and vascular disease: current therapeutic strategies. Expert Rev Cardiovasc Ther 4: 789-800, 2006.
13. Charo IF, Taubman MB. Chemokines in the pathogenesis of vascular disease. Circ Res 95: 858-866, 2004.
14. Chaudhuri V, Zhou L, Karasek M. Inflammatory cytokines induce the transformation of human dermal microvascular endothelial cells into myofibroblasts: a potential role in skin fibrogenesis. J Cutan Pathol 34: 146-153, 2007.
15. Chen J, Lopez JA. Interactions of platelets with subendothelium and endothelium. Microcirculation 12: 235-246, 2005.
16. Cybulsky MI, Gimbrone MA Jr. Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science 251: 788-791, 1991.
17. Davies MJ. Stability and instability: two faces of coronary atherosclerosis. The Paul Dudley White Lecture 1995. Circulation 94: 2013-2020, 1996.
18. Dellavalle A, Sampaolesi M, Tonlorenzi R, Tagliafico E, Sacchetti B, Perani L, Innocenzi A, Galvez BG, Messina G, Morosetti R, Li S, Belicchi M, Peretti G, Chamberlain JS, Wright WE, Torrente Y, Ferrari S, Bianco P, Cossu G. Pericytes of human skeletal muscle are myogenic precursors distinct from satellite cells. Nat Cell Biol 9: 255-267, 2007.
19. Dore-Duffy P. Pericytes: pluripotent cells of the blood brain barrier. Curr Pharm Des 14: 1581-1593, 2008.
20. Edelman DA, Jiang Y, Tyburski J, Wilson RF, Steffes C. Pericytes and their role in microvasculature homeostasis. J Surg Res 135: 305-311, 2006.
21. Eves R, Webb BA, Zhou S, Mak AS. Caldesmon is an integral component of podosomes in smooth muscle cells. J Cell Sci 119: 1691-1702, 2006.
22. Eyden B. The myofibroblast: a study of normal, reactive and neoplastic tissues, with an emphasis on ultrastructure. Part 1-normal and reactive cells. J Submicrosc Cytol Pathol 37: 109-204, 2005.
23. Fitzgibbon GM, Kafka HP, Leach AJ, Keon WJ, Hooper GD, Burton JR. Coronary bypass graft fate and patient outcome: angiographic follow-up of 5,065 grafts related to survival and reoperation in 1,388 patients during 25 years. J Am Coll Cardiol 28: 616-626, 1996.
24. Fleck RA, Rao LV, Rapaport SI, Varki N. Localization of human tissue factor antigen by immunostaining with monospecific, polyclonal antihuman tissue factor antibody. Thromb Res 59: 421-437, 1990.
25. Gawaz M, Langer H, May AE. Platelets in inflammation and atherogenesis. J Clin Invest 115: 3378-3384, 2005.
26. Griffin JH, Fernandez JA, Gale AJ, Mosnier LO. Activated protein C. J Thromb Haemost 5, Suppl 1: 73-80, 2007.
27. Hackett D, Davies G, Maseri A. Pre-existing coronary stenoses in patients with first myocardial infarction are not necessarily severe. Eur Heart J 9: 1317-1323, 1988.
28. Hammes HP. Pericytes and the pathogenesis of diabetic retinopathy. Horm Metab Res 37, Suppl 1: 39-43, 2005.
29. Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 352: 1685-1695, 2005.
30. Hassoun PM, Yu FS, Shedd AL, Zulueta JJ, Thannickal VJ, Lanzillo JJ, Fanburg BL. Regulation of endothelial cell xanthine dehydrogenase xanthine oxidase gene expression by oxygen tension. Am J Physiol Lung Cell Mol Physiol 266: L163-L171, 1994.
31. Helmbold P, Wohlrab J, Marsch WC, Nayak RC. Human dermal pericytes express 3G5 ganglioside-a new approach for microvessel histology in the skin. J Cutan Pathol 28: 206-210, 2001.
32. Hughes S, Chan-Ling T. Characterization of smooth muscle cell and pericyte differentiation in the rat retina in vivo. Invest Ophthalmol Vis Sci 45: 2795-2806, 2004.
33. Jaffe EA, Nachman RL, Becker CG, Minick CR. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J Clin Invest 52: 2745-2756, 1973.
34. Kher N, Marsh JD. Pathobiology of atherosclerosis-a brief review. Semin Thromb Hemost 30: 665-672, 2004.
35. Koyama T, Taka A. Myocardial capillary net and blood constituents in streptozotocin (STZ)-induced diabetic rats. Adv Exp Med Biol 645: 187-192, 2009.
36. Lau GT, Lowe HC, Kritharides L. Cardiac saphenous vein bypass graft disease. Semin Vasc Med 4: 153-159, 2004.
37. Libby P. Atherosclerosis: disease biology affecting the coronary vasculature. Am J Cardiol 98: 3Q-9Q, 2006.
38. Martinez MC, Tesse A, Zobairi F, Andriantsitohaina R. Shed membrane microparticles from circulating and vascular cells in regulating vascular function. Am J Physiol Heart Circ Physiol 288: H1004-H1009, 2005.
39. Mazanet R, Franzini-Armstrong C. Scanning electron microscopy of pericytes in rat red muscle. Microvasc Res 23: 361-369, 1982.
40. Mitra AK, Dhume AS, Agrawal DK. "Vulnerable plaques"-ticking of the time bomb. Can J Physiol Pharmacol 82: 860-871, 2004.
41. Morel O, Toti F, Hugel B, Bakouboula B, Camoin-Jau L, Dignat-George F, Freyssinet JM. Procoagulant microparticles: disrupting the vascular homeostasis equation? Arterioscler Thromb Vasc Biol 26: 2594-2604, 2006.
42. Motwani JG, Topol EJ. Aortocoronary saphenous vein graft disease: pathogenesis, predisposition, and prevention. Circulation 97: 916-931, 1998.
43. Murphy GJ, Angelini GD. Insights into the pathogenesis of vein graft disease: lessons from intravascular ultrasound. Cardiovasc Ultrasound 2: 1-8, 2004.
44. Nees S, Herzog V, Becker BF, Bock M, Des Rosiers C, Gerlach E. The coronary endothelium: a highly active metabolic barrier for adenosine. Basic Res Cardiol 80: 515-529, 1985.
45. Newby AC, Zaltsman AB. Molecular mechanisms in intimal hyperplasia. J Pathol 190: 300-309, 2000.
46. Osterud B. A global view on the role of monocytes and platelets in atherogenesis. Thromb Res 85: 1-22, 1997.
47. Osterud B, Bjorklid E. Sources of tissue factor. Semin Thromb Hemost 32: 11-23, 2006.
48. Owens GK, Kumar MS, Wamhoff BR. Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiol Rev 84: 767-801, 2004.
49. Ozer K, Cilingiroglu M. Vulnerable plaque: definition, detection, treatment, and future implications. Curr Atheroscler Rep 7: 121-126, 2005.
50. Paulin D, Li Z. Desmin: a major intermediate filament protein essential for the structural integrity and function of muscle. Exp Cell Res 301: 1-7, 2004.
51. Peykar S, Angiolillo DJ, Bass TA, Costa MA. Saphenous vein graft disease. Minerva Cardioangiol 52: 379-390, 2004.
52. Poston RS, Gu J, Brown JM, Gammie JS, White C, Nie L, Pierson RN 3rd, Griffith BP. Endothelial injury and acquired aspirin resistance as promoters of regional thrombin formation and early vein graft failure after coronary artery bypass grafting. J Thorac Cardiovasc Surg 131: 122-130, 2006.
53. Rao RN, Falls DG, Gerrity RG, Sethuraman SN, Thiruvaiyaru DS. Intimal thickness and layering, and smooth muscle cell phenotypes in aorta of youth. Pathobiology 68: 18-28, 2000.
54. Robertson AK, Hansson GK. T cells in atherogenesis: for better or for worse? Arterioscler Thromb Vasc Biol 26: 2421-2432, 2006.
55. Scholz T, Temmler U, Krause S, Heptinstall S, Losche W. Transfer of tissue factor from platelets to monocytes: role of platelet-derived microvesicles and CD62P. Thromb Haemost 88: 1033-1038, 2002.
56. Schwartz SM. Perspectives series: cell adhesion in vascular biology. Smooth muscle migration in atherosclerosis and restenosis. J Clin Invest 99: 2814-2816, 1997.
57. Schwartz SM, Majesky MW, Murry CE. The intima: development and monoclonal responses to injury. Atherosclerosis 118: S125-S140, 1995.
58. Senoo H. Structure and function of hepatic stellate cells. Med Electron Microsc 37: 3-15, 2004.
59. Shepro D, Morel NM. Pericyte physiology. FASEB J 7: 1031-1038, 1993.
60. Shi Y, O'Brien JE, Fard A, Mannion JD, Wang D, Zalewski A. Adventitial myofibroblasts contribute to neointimal formation in injured porcine coronary arteries. Circulation 94: 1655-1664, 1996.
61. Shuhaiber JH, Evans AN, Massad MG, Geha AS. Mechanisms and future directions for prevention of vein graft failure in coronary bypass surgery. Eur J Cardiothorac Surg 22: 387-396, 2002.
62. Solberg S, Osterud B, Larsen T, Sorlie D. Lack of ability to synthesize tissue factor by endothelial cells in intact human saphenous veins. Blood Coagul Fibrinolysis 1: 595-600, 1990.
63. Stary HC, Blankenhorn DH, Chandler AB, Glagov S, Insull W, Jr, Richardson M, Rosenfeld ME, Schaffer SA, Schwartz CJ, Wagner WD. A definition of the intima of human arteries and of its atherosclerosisprone regions. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association. Circulation 85: 391-405, 1992.
64. Stassen JM, Arnout J, Deckmyn H. The hemostatic system. Curr Med Chem 11: 2245-2260, 2004.
65. Stockand JD, Sansom SC. Glomerular mesangial cells: electrophysiology and regulation of contraction. Physiol Rev 78: 723-744, 1998.
66. Suematsu M, Aiso S. Professor Toshio Ito: a clairvoyant in pericyte biology. Keio J Med 50: 66-71, 2001.
67. Tracy PB, Robinson RA, Worfolk LA, Allen DH. Procoagulant activities expressed by peripheral blood mononuclear cells. Methods Enzymol 222: 281-299, 1993.
68. van der Wal AC, Li X, de Boer OJ. Tissue factor expression in the morphologic spectrum of vulnerable atherosclerotic plaques. Semin Thromb Hemost 32: 40-47, 2006.
69. van Hinsbergh VW. The endothelium: vascular control of haemostasis. Eur J Obstet Gynecol Reprod Biol 95: 198-201, 2001.
70. Verhamme P, Hoylaerts MF. The pivotal role of the endothelium in haemostasis and thrombosis. Acta Clin Belg 61: 213-219, 2006.
71. Viles-Gonzalez JF, Fuster V, Badimon JJ. Links between inflammation and thrombogenicity in atherosclerosis. Curr Mol Med 6: 489-499, 2006.
72. von Tell D, Armulik A, Betsholtz C. Pericytes and vascular stability. Exp Cell Res 312: 623-629, 2006.
73. Weiss DR, Juchem G, Kemkes BM, Gansera B, Nees S. Extensive deendothelialization and thrombogenicity in routinely prepared vein grafts for coronary bypass operations: facts and remedy. Int J Clin Exp Med 2: 95-113, 2009.
74. Wellings DA, Atherton E. Standard Fmoc protocols. Methods Enzymol 289: 44-67, 1997.
75. Wilcox JN, Smith KM, Schwartz SM, Gordon D. Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque. Proc Natl Acad Sci USA 86: 2839-2843, 1989.
76. Yamagishi S, Imaizumi T. Pericyte biology and diseases. Int J Tissue React 27: 125-135, 2005.
77. Zimmermann K. Der feinere Bau der Blutkapillaren. Z Anat Entwickl-Gesch 28: 29-110, 1923.