Synergism between ammonia, lactic acid and carboxylic acids as kairomones in the host-seeking behaviour of the malaria mosquito Anopheles gambiae sensu stricto (Diptera: Culicidae)

Chemical Senses

Volumn 30, Issue 2, 2005, Pages 145-152

  Smallegange, Renate C ^a   Qiu, Yu Tong ^a   van Loon, Joop A ^a   Takken, Willem ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Dual port olfactometer; Host odours; Human volatiles; Olfaction; Sweat

Indexed keywords

AMMONIA; CARBOXYLIC ACID; CHEMOATTRACTANT; LACTIC ACID; PHEROMONE;

AEDES AEGYPTI; AFRICA; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANOPHELES GAMBIAE; ARTICLE; CONTROLLED STUDY; FEMALE; HOST SELECTION; MALARIA; MOSQUITO; NONHUMAN; ODOR; OLFACTOMETRY; PARASITE VECTOR; PLASMODIUM MALARIAE; PRIORITY JOURNAL; ANIMAL; APPETITE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; DRUG POTENTIATION; HOST PARASITE INTERACTION; HUMAN; PHYSIOLOGY;

AEDES AEGYPTI; ANOPHELES GAMBIAE; CULICIDAE; DIPTERA;

AMMONIA; ANIMALS; ANOPHELES GAMBIAE; APPETITIVE BEHAVIOR; CARBOXYLIC ACIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; FEMALE; HOST-PARASITE RELATIONS; HUMANS; LACTIC ACID; ODORS; PHEROMONES;

EID: 20144371443     PISSN: 0379864X     EISSN: None     Source Type: Journal    
DOI: 10.1093/chemse/bji010     Document Type: Article

References (36)

1. Acree, F. Jr, Turner, R.B., Gouck, H.K., Beroza, M. and Smith, N. (1968) L-Lactic acid: a mosquito attractant isolated from humans. Science, 161, 1346-1347.
2. Bernier, U.R., Booth, M.M. and Yost, R.A. (1999) Analysis of human skin emanations by gas chromatography/mass spectrometry. 1. Thermal desorption of attractants for the yellow fever mosquito (Aedes aegypti) from handled glass beads. Anal. Chem., 71, 1-7.
3. Bernier, U.R., Kline, D.L., Barnard, D.R., Schreck, C.E. and Yost, R.A. (2000) Analysis of human skin emanations by gas chromatography/mass spectrometry. 2. Identification of volatile compounds that are candidate attractants for the yellow fever mosquito (Aedes aegypti). Anal. Chem., 72, 747-756.
4. Bosch, O.J., Geier, M. and Boeckh, J. (2000) Contribution of fatty acids to olfactory host finding of female Aedes aegypti. Chem. Senses, 25, 323-330.
5. Braks, M.A.H. and Takken, W. (1999) Incubated human sweat but not fresh sweat attracts the malaria mosquito Anopheles gambiae sensu stricto. J. Chem. Ecol., 25, 663-672.
6. Braks, M.A.H., Cork, A. and Takken, W. (1997) Olfactometer studies on the attraction of Anopheles gambiae sensu stricto (Diptera: Culicidae) to human sweat. Proc. Exp. Appl. Entomol., 8, 99-104.
7. Braks, M.A.H., Meijerink, J. and Takken, W. (2001) The response of the malaria mosquito, Anopheles gambiae to two components of human sweat, ammonia and L-lactic acid, in an olfactometer. Physiol. Entomol., 26, 142-148.
8. Coluzzi, M., Sabatini, A., Petrarca, V. and Di Deco, M.A. (1979) Chromosomal differentiation and adaptation to human environments in the Anopheles gambiae complex. Trans. R. Soc. Trop. Med. Hyg., 73, 483-497.
9. Cork, A. and Park, K.C. (1996) Identification of electrophsiologically-active compounds for the malaria mosquito, Anopheles gambiae, in human sweat extracts. Med. Vet. Entomol., 10, 269-276.
10. Costantini, C., Gibson, G., Sagnon, N.F., della Torre, A., Brady, J. and Coluzzi, M. (1996) Mosquito responses to carbon dioxide in a West African Sudan savanna village. Med. Vet. Entomol., 10, 220-227.
11. Costantini, C., Sagnon, N.F., della Torre, A., Diallo, M., Brady, J., Gibson, G. and Coluzzi, M. (1998) Odor-mediated host preferences of West African mosquitoes, with particular reference to malaria vectors. Am. J. Trop. Med. Hyg., 58, 56-63.
12. Costantini, C., Birkett, M.A., Gibson, G., Ziesmann, J., Sagnon, N'F., Mohammed, H.A., Coluzzi, M. and Pickett, J.A. (2001) Electroantennogram and behavioural responses of the malaria vector Anopheles gambiae to human-specific sweat components. Med. Vet. Entomol., 15, 259-266.
13. De Jong, R. and Knols, B.G.J. (1995) Olfactory responses of host-seeking Anopheles gambiae Giles s.s. (Diptera: Culicidae). Acta Trop., 59, 333-335.
14. Dekker, T., Steib, B., Cardé, R.T. and Geier, M. (2002) L-Lactic acid: a human-signifying host cue for the anthropophilic mosquito Anopheles gambiae. Med. Vet. Entomol., 16, 91-98.
15. Eiras, A.E. and Jepson, P.C. (1991) Host location by Aedes aegypti (Diptera: Culicidae): a wind tunnel study of chemical cues. Bull. Entomol. Res., 81, 151-160.
16. Geier, M., Sass, H. and Boeckh, J. (1996) A search for components in human body odour that attract females of Aedes aegypti. Olfaction in mosquito-host interactions. Ciba Foundation Symposium, 200, 132-148.
17. Geier, M., Bosch, O.J. and Boeckh, J. (1999) Ammonia as an attractive component of host odour for the yellow fever mosquito, Aedes aegypti. Chem. Senses, 24, 647-653.
18. Haddow, A.J. (1942) The mosquito fauna and climate of native huts at Kisumu, Kenya. Bull. Entomol. Res. 33, 91-142.
19. Healy, T.P. and Copland, M.J.W. (2000) Human sweat and 2-oxopentanoic acid elicit a landing response from Anopheles gambiae. Med. Vet. Entomol., 14, 195-200.
20. Knols, B.G.J., Jong, de R. and Takken, W. (1994) Trapping system for testing olfactory responses of the malaria mosquito Anopheles gambiae in a wind tunnel. Med. Vet. Entomol., 8, 386-388.
21. Larson, T.V., Covert, D.S. and Frank, R. (1979) A method for continuous measurement of ammonia in respiratory airways. J. Appl. Physiol.: Respirat. Environ. Exercise Physiol., 46, 603-607.
22. Knols, B.G.J., Van Loon, J.J.A., Cork, A., Robinson, R.D., Adam, W., Meijerink, J., Jong, de R. and Takken, W. (1997). Behavioural and electrophysiological responses of the female malaria mosquito Anopheles gambiae (Diptera: Culicidae) to Limburger cheese volatiles. Bull. Entomol. Res., 87, 151-159.
23. Mboera, L.E.G., Knols, B.G.J., Takken, W. and della Torre, A. (1997) The response of Anopheles gambiae s.l. and A. funestus (Diptera: Culicidae) to tents baited with human odour or carbon dioxide in Tanzania. Bull. Entomol. Res., 87, 173-178.
24. Meijerink, J., Braks, M.A.H., Brack, A.A., Adam, W., Dekker, T., Posthumus, M.A., Van Beek, T.A. and Van Loon J.J.A. (2000) Identification of olfactory stimulants for Anopheles gambiae from human sweat samples. J. Chem. Ecol., 26, 1367-1382.
25. Murlis, J., Elkinton, J.S. and Cardé, R.T. (1992) Odor plumes and how insects use them. Annu. Rev. Entomol., 37, 505-532.
26. Oude Voshaar, J.H. (1994) Statistiek voor onderzoekers. Met voorbeelden uitdelandbouw-enmilieuwetenschappen. Wageningen Pers, Wageningen, Nederland.
27. Pates, H.V., Takken, W., Curtis, C.F., Huisman, P.W., Akinpelu, O. and Gill, G.S. (2001a) Unexpected anthropophagic behaviour in Anopheles quadriannulatus. Med. Vet. Entomol., 15, 293-298.
28. Pates, H.V., Takken, W., Stuke, K. and Curtis, C.F. (2001b) Differential behaviour of Anopheles gambiae sensu stricto (Diptera: Culicidae) to human and cow odours in the laboratory. Bull. Entomol. Res., 91, 289-296.
29. Ribbands, C.R. (1950) Studies on the attractiveness of human populations to anophelines. Bull. Entomol. Res., 40, 227-238.
30. Smallegange, R.C., Geier, M. and Takken, W. (2002) Behavioural responses of Anopheles gambiae to ammonia, lactic acid and a fatty acid in a y-tube olfactometer. Proc. Exp. Appl. Entomol., 13, 147-152.
31. Smith, C.N., Smith, N., Gouck, H.K., Weidhaas, D.E., Gilbert, I.H., Mayer, M.S., Smittle, B.J. and Hofbauer, A. (1970) L-Lactic acid as a factor in the attraction of Aedes aegypti (Diptera: Culicidae) to human hosts. Ann. Entomol. Soc. Am., 63, 760-770.
32. Sokal, R.R. and Rohlf, F.J. (1998) Biometry: The Principles and Practice of Statistics in Biological Research, 3rd edn. W.H. Freeman, New York.
33. Takken, W. (1991) The role of olfaction in host-seeking of mosquitoes: a review. Insect Sci. Appl., 12, 287-295.
34. Takken, W. and Knols, B.G.J. (1999) Odor-mediated behavior of afrotropical malaria mosquitoes. Annu. Rev. Entomol., 44, 131-157.
35. White, G.B. (1974) Anopheles gambiae complex and disease transmission in Africa. Trans. R. Soc. Trop. Med. Hyg., 68, 273-301.
36. Zeng, X.-N., Leyden, J.J., Lawley, H.J., Sawano, K., Nohara, I. and Preti, G. (1991) Analysis of characteristic odors from human male axillae. J. Chem. Ecol., 17, 1469-1492.