AID for reprogramming

Cell Research

Volumn 20, Issue 3, 2010, Pages 253-255

  Agarwal, Suneet ^a,b,c,d,e   Daley, George Q ^a,b,c,d,e  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c HARVARD STEM CELL INSTITUTE   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AICDA (ACTIVATION INDUCED CYTIDINE DEAMINASE); AICDA (ACTIVATION-INDUCED CYTIDINE DEAMINASE); CYTIDINE DEAMINASE; HOMEODOMAIN PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; SMALL INTERFERING RNA;

ANIMAL; ARTICLE; CELL FUSION; CYTOLOGY; HUMAN; METABOLISM; MOUSE; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL;

ANIMALS; CELL FUSION; CYTIDINE DEAMINASE; HOMEODOMAIN PROTEINS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MICE; NUCLEAR REPROGRAMMING; OCTAMER TRANSCRIPTION FACTOR-3; RNA, SMALL INTERFERING;

EID: 77749234196     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2010.30     Document Type: Article

References (12)

1. Gurdon JB, Byrne JA. The first halfcentury of nuclear transplantation. Proc Natl Acad Sci USA 2003; 100:8048-8052.
2. Miller RA, Ruddle FH. Pluripotent teratocarcinoma-thymus somatic cell hybrids. Cell 1976; 9:45-55.
3. Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126:663-676.
4. Bhutani N, Brady JJ, Damian M, Sacco A, Corbel SY, Blau HM. Reprogramming towards pluripotency requires AID-dependent DNA demethylation. Nature 2009 Dec 21. doi:10.1038/nature08752
5. Morgan HD, Santos F, Green K, Dean W, Reik W. Epigenetic reprogramming in mammals. Hum Mol Genet 2005; 14 Spec:R47-R58.
6. Ooi SK, Bestor TH. The colorful history of active DNA demethylation. Cell 2008; 133:1145-1148.
7. Delker RK, Fugmann SD, Papavasiliou FN. A coming-of-age story: activationinduced cytidine deaminase turns 10. Nat Immunol 2009; 10:1147-1153.
8. Morgan HD, Dean W, Coker HA, Reik W, Petersen-Mahrt SK. Activationinduced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming. J Biol Chem 2004; 279:52353-52360.
9. Rai K, Huggins IJ, James SR, Karpf AR, Jones DA, Cairns BR. DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45. Cell 2008; 135:1201-1212.
10. Mayer W, Niveleau A, Walter J, Fundele R, Haaf T. Demethylation of the zygotic paternal genome. Nature 2000; 403:501-502.
11. Meissner A, Mikkelsen TS, Gu H, et al. Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature 2008; 454:766-770.
12. Popp C, Dean W, Feng S, et al. Genomewide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency. Nature 2010 Jan 22. doi:10.1038/nature08829