Cyclophilin A as negative regulator of apoptosis by sequestering cytochrome c

Biochemical and Biophysical Research Communications

Volumn 393, Issue 2, 2010, Pages 325-330

  Bonfils, Claude ^a   Bec, Nicole ^a   Larroque, Christian ^a   Del Rio, Maguy ^a   Gongora, Céline ^a   Pugnière, Martine ^b   Martineau, Pierre ^a  

^a INSERM   (France)

^b CNRS   (France)

Author keywords

Apoptosis; Brain; Cyclophilin A; Cytochrome c; Phosphatidylethanolamine binding protein; Procaspase 3; Tumor

Indexed keywords

CYCLOPHILIN A; CYTOCHROME C; PROCASPASE 3; STAUROSPORINE;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN TISSUE; CELL FREE SYSTEM; CELL STRAIN HCT116; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; TUMOR CELL;

ANIMALS; APOPTOSIS; BRAIN; CASPASE 3; CELL LINE, TUMOR; CYCLOPHILIN A; CYTOCHROMES C; HUMANS; NEOPLASMS; NEURONS;

EID: 77649336215     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.01.135     Document Type: Article

References (31)

1. Strasser A., O'Connor L., and Dixit V.M. Apoptosis signalling. Annu. Rev. Biochem. 69 (2000) 217-245
2. Daugas E., Nochy D., Ravagnan L., Loeffler M., Susin S.A., Zamzami N., and Kroemer G. Apoptosis-inducing factor (AIF): a ubiquitous mitochondrial oxidoreductase involved in apoptosis. FEBS Lett. 476 (2000) 118-123
3. Hishiya A., and Takayama S. Molecular chaperones as regulators of cell death. Oncogene 27 (2008) 6489-6506
4. Lim S.O., Park S.-J., Kim W., Park S.G., Kim H.-J., Kim Y.-I., Sohn T.-S., Noh J.-H., and Jung G. Proteome analysis of hepatocellular carcinoma. Biochem. Biophys. Res. Commun. 291 (2002) 1031-1037
5. Yang H., Chen J., Yang J., Qiao S., Zhao S., and Yu L. Cyclophilin A is upregulated in small cell lung cancer and activates ERK1/2 signal. Biochem. Biophys. Res. Commun. 361 (2007) 763-767
6. Campa M.J., Wang M.Z., Howard B., Fitzgerald M.C., and Patz Jr. E.F. Protein expression profiling identifies macrophage migration inhibitory factor and Cyclophilin A as potential molecular targets in non-small cell lung cancer. Cancer Res. 63 (2003) 1652-1656
7. Shen J., Person M.D., Zhu J., Abbruzzese J.L., and Li D. Protein expression profiles in pancreatic adenocarcinoma compared with normal pancreatic tissue and tissue affected by pancreatitis as detected by two-dimensional gel electrophoresis and mass spectrometry. Cancer Res. 64 (2004) 9018-9026
8. Li Z., Zhao X., Bai S., Wang Z., Chen L., Wei Y., and Huang C. Proteomics identification of Cyclophilin A as a potential prognostic factor and therapeutic target in endometrial carcinoma. Mol. Cell. Proteomics 7 (2008) 1810-1823
9. Qi Y.J., He Q.Y., Ma Y.F., Du Y.W., Liu G.C., Li Y.J., Tsao G.S., Ngai S.M., and Chiu J.F. Proteomic identification of malignant transformation-related proteins in esophageal squamous cell carcinoma. J. Cell. Biochem. 104 (2008) 1625-1635
10. Howard B.A., Furumai R., Campa M.J., Rabbani Z.N., Vujaskovic Z., Wang X.-F., and Patz Jr. E.F. Stable RNA interference-mediated suppression of Cyclophilin A diminishes non-small-cell lung tumor growth in vivo. Cancer Res. 65 (2005) 8853-8860
11. Choi K.J., Piao Y.J., Lim M.J., Kim J.H., Ha J., Choe W., and Kim S.S. Overexpressed Cyclophilin A in cancer cells renders resistance to hypoxia- and cisplatin-induced cell death. Cancer Res. 67 (2007) 3654-3662
12. Bauer K., Kretzschmar A.K., Cvijic H., Blumert C., Löffler D., Brocke-Heidrich K., Schiene-Fischer C., Fischer G., Sinz A., Clevenger C.V., and Horn F. Cyclophilins contribute to Stat3 signaling and survival of multiple myeloma cells. Oncogene (2009) (Epub ahead of print)
13. Göldner F.M., and Patrick J.W. Neuronal localization of the cyclophilin A protein in the adult rat brain. J. Comp. Neurol. 372 (1996) 283-293
14. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
15. Nicholson D.W., Ali A., Thornberry N.A., Vaillancourt J.P., Ding C.K., Gallant M., Gareau Y., Griffin P.R., Labelle M., Lazebnik Y.A., Munday N.A., Raju S.M., Smulson M.E., Yamin T.-T., Yu V.L., and Miller D.K. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 376 (1995) 37-43
16. Liu X., Kim C.N., Yang J., Jemmerson R., and Wang X. Induction of apoptotic program in cell-free extracts: requirement of dATP and cytochrome c. Cell 86 (1996) 147-157
17. Hampton M.B., Zhivotovsky B., Slater F.G., Burgess D.H., and Orrenius S. Importance of the redox state of cytochrome c during caspase activation in cytosolic extracts. Biochem. J. 329 (1998) 95-99
18. Hummel J.P., and Dreyer W.J. Measurement of protein-binding phenomena by gel filtration. Biochim. Biophys. Acta 63 (1962) 530-532
19. Berger G., and Girault G. Macromolecule-ligand binding studied by the Hummel and Dreyer method: current state of the methodology. J. Chromatogr. B 797 (2003) 51-61
20. Fischer G., Wittmann-Liebold B., Lang K., Kiefhaber T., and Schmid F.W. Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins. Nature 337 (1989) 476-478
21. Wang P., and Heitman J. The cyclophilins. Genome Biol. 6 (2005) 226
22. Koletsky A.J., Harding M.W., and Handschumacher R.E. Cyclophilin: distribution and variant properties in normal and neoplastic tissues. J. Immunol. 137 (1986) 1054-1059
23. Odabaei G., Chatterjee D., Jazirehi A.R., Goodglick L., Yeung K., and Bonavida B. Raf-1 kinase inhibitor protein: structure, function, regulation of cell signalling, and pivotal role in apoptosis. Adv. Cancer Res. 91 (2004) 169-200
24. Bernier I., and Jollès P. Purification and characterization of a basic 23 kDa cytosolic protein from bovine brain. Biochim. Biophys. Acta 790 (1984) 174-181
25. Jin Z.-G., Melaragno M.G., Liao D.-F., Yan C., Haendeler J., Suh Y.-A., Lambeth J.D., and Berk B.C. Cyclophilin A is a secreted growth factor induced by oxidative stress. Circ. Res. 87 (2000) 789-796
26. Franke E.K., Yuan H.E.-H., and Luban J. Specific incorporation of cyclophilin A into HIV-1 virions. Nature 372 (1994) 359-362
27. Thali M., Bukovsky A., Kondo E., Rosenwirth B., Walsh C.T., Sodroski J., and Gôttlinger H.G. Functional association of cyclophilin A with HIV-1 virions. Nature 372 (1994) 363-365
28. Montague J.W., Hughes Jr. F.M., and Cidlowski J.A. Native recombinant cyclophilins A, B, and C degrade DNA independently of peptidylprolyl cis-trans-isomerase activity. Potential roles of cyclophilins in apoptosis. J. Biol. Chem. 272 (1997) 6677-6684
29. Candé C., Vahsen N., Kouranti I., Schmitt E., Daugas E., Spahr C., Luban J., Kroemer R.T., Giordanetto F., Garrido C., Penninger J.M., and Kroemer G. AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis. Oncogene 23 (2004) 1514-1521
30. Bruey J.-M., Ducasse C., Bonniaud P., Ravagnan L., Susin S.A., Daiaz-Latoud C., Gurbuxani S., Arrigo A.-P., Kroemer G., Solary E., and Garrido C. Hsp27 negatively regulates cell death by interacting with cytochrome c. Nat. Cell Biol. 2 (2000) 645-652
31. Calderwood S.K., Khaleque A., Sawyer D.B., and Ciocca D.R. Heat shock proteins in cancer: chaperones of tumorigenesis. Trends Biochem. Sci. 31 (2006) 164-172