Toxoplasma gondii infection specifically increases the levels of key host microRNAs

PLoS ONE

Volumn 5, Issue 1, 2010, Pages

  Zeiner, Gusti M ^a   Norman, Kara L ^a   Thomson, J Michael ^b   Hammond, Scott M ^b   Boothroyd, John C ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; GENE EXPRESSION; HOST CELL; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNE RESPONSE; MICROARRAY ANALYSIS; MODULATION; NEOSPORA CANINUM; NONHUMAN; PROMOTER REGION; REGULATORY MECHANISM; RNA ISOLATION; TOXOPLASMOSIS; UPREGULATION; CELL CULTURE; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; NORTHERN BLOTTING; PARASITOLOGY; PATHOGENICITY; TOXOPLASMA;

ANIMALIA; MAMMALIA; NEOSPORA CANINUM; TOXOPLASMA; TOXOPLASMA GONDII;

BLOTTING, NORTHERN; CELLS, CULTURED; HOST-PATHOGEN INTERACTIONS; HUMANS; MICRORNAS; PROMOTER REGIONS, GENETIC; TOXOPLASMA; TOXOPLASMOSIS; TRANSCRIPTION, GENETIC;

EID: 77649322104     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0008742     Document Type: Article

References (41)

1. Montoya JG, Liesenfeld O (2004) Toxoplasmosis. Lancet 363: 1965-1976.
2. Boothroyd JC, Dubremetz JF (2008) Kiss and spit: the dual roles of Toxoplasma rhoptries. Nat Rev Microbiol 6: 79-88.
3. Phelps ED, Sweeney KR, Blader IJ (2008) Toxoplasma gondii rhoptry discharge correlates with activation of the early growth response 2 host cell transcription factor. Infect Immun 76: 4703-4712.
4. Saeij JP, Boyle JP, Coller S, Taylor S, Sibley LD, et al. (2006) Polymorphic secreted kinases are key virulence factors in toxoplasmosis. Science 314: 1780-1783.
5. Saeij JP, Coller S, Boyle JP, Jerome ME, White MW, et al. (2007) Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue. Nature 445: 324-327.
6. Lüder CG, Gross U (2005) Apoptosis and its modulation during infection with Toxoplasma gondii: molecular mechanisms and role in pathogenesis. Curr Top Microbiol Immunol 289: 219-237.
7. Persson EK, Agnarson AM, Lambert H, Hitziger N, Yagita H, et al. (2007) Death receptor ligation or exposure to perforin trigger rapid egress of the intracellular parasite Toxoplasma gondii. J Immunol 179: 8357-8365.
8. Brunet J, Pfaff AW, Abidi A, Unoki M, Nakamura Y, et al. (2008) Toxoplasma gondii exploits UHRF1 and induces host cell cycle arrest at G2 to enable its proliferation. Cell Microbiol 10: 908-920.
9. Dvorak JA, Crane MS (1981) Vertebrate cell cycle modulates infection by protozoan parasites. Science 214: 1034-1036.
10. Lavine MD, Arrizabalaga G (2009) Induction of mitotic S-phase of host and neighboring cells by Toxoplasma gondii enhances parasite invasion. Mol Biochem Parasitol 164: 95-99.
11. Molestina RE, El-Guendy N, Sinai AP (2008) Infection with Toxoplasma gondii results in dysregulation of the host cell cycle. Cell Microbiol 10: 1153-1165.
12. Blader IJ, Manger ID, Boothroyd JC (2001) Microarray analysis reveals previously unknown changes in Toxoplasma gondii-infected human cells. J Biol Chem 276: 24223-24231.
13. Nelson MM, Jones AR, Carmen JC, Sinai AP, Burchmore R, et al. (2008) Modulation of the host cell proteome by the intracellular apicomplexan parasite Toxoplasma gondii. Infect Immun 76: 828-844.
14. Hobert O (2008) Gene regulation by transcription factors and microRNAs. Science 319: 1785-1786.
15. Grimson A, Farh KK, Johnston WK, Garrett-Engele P, Lim LP, et al. (2007) MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol Cell 27: 91-105.
16. Du T, Zamore PD (2005) microPrimer: the biogenesis and function of microRNA. Development 132: 4645-4652.
17. Vasudevan S, Tong Y, Steitz JA (2007) Switching from Repression to Activation: MicroRNAs Can Up-Regulate Translation. Science 318: 1931-1934.
18. Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB (2003) Prediction of mammalian microRNA targets. Cell 115: 787-798.
19. Mendell JT (2008) miRiad roles for the miR-17-92 cluster in development and disease. Cell 133: 217-222.
20. Xiao C, Rajewsky K (2009) MicroRNA control in the immune system: basic principles. Cell 136: 26-36.
21. Lee RC, Feinbaum RL, Ambros V (1993) The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75: 843-854.
22. Wightman B, Ha I, Ruvkun G (1993) Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75: 855-862.
23. Gottwein E, Mukherjee N, Sachse C, Frenzel C, Majoros WH, et al. (2007) A viral microRNA functions as an orthologue of cellular miR-155. Nature 450: 1096-1099.
24. O'Connell RM, Taganov KD, Boldin MP, Cheng G, Baltimore D (2007) MicroRNA-155 is induced during the macrophage inflammatory response. Proc Natl Acad Sci USA 104: 1604-1609.
25. Sarnow P, Jopling CL, Norman KL, Schütz S, Wehner KA (2006) MicroRNAs: expression, avoidance and subversion by vertebrate viruses. Nat Rev Microbiol 4: 651-659.
26. Taganov KD, Boldin MP, Chang KJ, Baltimore D (2006) NF-kappaBdependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci USA 103: 12481-12486.
27. Triboulet R, Mari B, Lin YL, Chable-Bessia C, Bennasser Y, et al. (2007) Suppression of microRNA-silencing pathway by HIV-1 during virus replication. Science 315: 1579-1582.
28. Lotterman CD, Kent OA, Mendell JT (2008) Functional integration of microRNAs into oncogenic and tumor suppressor pathways. Cell Cycle 7.
29. He L, Thomson JM, Hemann MT, Hernando-Monge E, Mu D, et al. (2005) A microRNA polycistron as a potential human oncogene. Nature 435: 828-833.
30. Xiao C, Srinivasan L, Calado DP, Patterson HC, Zhang B, et al. (2008) Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes. Nat Immunol 9: 405-414.
31. Thomson JM, Parker J, Perou CM, Hammond SM (2004) A custom microarray platform for analysis of microRNA gene expression. Nat Methods 1: 47-53.
32. Ventura A, Young AG, Winslow MM, Lintault L, Meissner A, et al. (2008) Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell 132: 875-886.
33. TODARO GJ, GREEN H (1963) Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. J Cell Biol 17: 299-313.
34. PULVERTAFT JV (1964) CYTOLOGY OF BURKITT'S TUMOUR (AFRICAN LYMPHOMA). Lancet 1: 238-240.
35. Dubey JP, Carpenter JL, Speer CA, Topper MJ, Uggla A (1988) Newly recognized fatal protozoan disease of dogs. J Am Vet Med Assoc 192: 1269-1285.
36. Sundermann CA, Estridge BH (1999) Growth of and competition between Neospora caninum and Toxoplasma gondii in vitro. Int J Parasitol 29: 1725-1732.
37. O'Donnell KA, Wentzel EA, Zeller KI, Dang CV, Mendell JT (2005) c-Myc-regulated microRNAs modulate E2F1 expression. Nature 435: 839-843.
38. Woods K, Thomson JM, Hammond SM (2007) Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors. J Biol Chem 282: 2130-2134.
39. Lu Y, Thomson JM, Wong HY, Hammond SM, Hogan BL (2007) Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells. Dev Biol 310: 442-453.
40. Petrocca F, Visone R, Onelli MR, Shah MH, Nicoloso MS, et al. (2008) E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer. Cancer Cell 13: 272-286.
41. Gilbert LA, Ravindran S, Turetzky JM, Boothroyd JC, Bradley PJ (2007) Toxoplasma gondii targets a protein phosphatase 2C to the nuclei of infected host cells. Eukaryotic Cell 6: 73-83.