Progenitor cell therapy for traumatic brain injury: Effect of serum osmolarity on cell viability and cytokine production

Regenerative Medicine

Volumn 5, Issue 1, 2010, Pages 65-71

  Walker, Peter A ^a   Jimenez, Fernando ^a   Cox, Charles S ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

Cytokines; Inflammation; Mesenchymal stem cells; Osmolarity

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 4;

ADULT STEM CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; GRAFT SURVIVAL; HYPEROSMOLARITY; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MULTIPOTENT STEM CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SERUM OSMOLARITY; THERAPY EFFECT; TRAUMATIC BRAIN INJURY;

ANIMALS; BRAIN INJURIES; CELL CULTURE TECHNIQUES; CELL SURVIVAL; COMBINED MODALITY THERAPY; CYTOKINES; HYPERTONIC SOLUTIONS; INFLAMMATION; MESENCHYMAL STEM CELL TRANSPLANTATION; RATS;

EID: 77649309871     PISSN: 17460751     EISSN: None     Source Type: Journal    
DOI: 10.2217/rme.09.73     Document Type: Article

References (34)

1. Thurman DJ, Alverson C, Dunn KA et al.: Traumatic brain injury in the United States: a public health perspective. J. Head Trauma Rehabil. 14(6), 602-615 (1999).
2. Consensus conference: Rehabilitation of persons with traumatic brain injury. NIH consensus development panel on rehabilitation of persons with traumatic brain injury. JAMA 282(10), 974-983 (1999).
3. Hawley CA, Ward AB, Magnay AR et al..: Outcomes following childhood head injury: a population study. J. Neurol. Neurosurg. Psychiatr. 75(5), 737-742 (2004).
4. Cowen TD, Meythaler JM, DeVivo MJ et al..: Influence of early variables in traumatic brain injury on functional independence measure scores and rehabilitation length of stay and charges. Arch. Phys. Med. Rehabil. 76(9), 797-803 (1995).
5. Gray DS, Burnham RS: Preliminary outcome analysis of a long-term rehabilitation program for severe acquired brain injury. Arch. Phys. Med. Rehabil. 81(11), 1447-1456 (2008).
6. Walker P, Harting MT, Baumgartner JE, Fletcher S, Strobel N, Cox CS Jr: Modern approaches to pediatric brain injury therapy. J. Trauma 67(Suppl. 2), S120-S127 (2009).
7. Pinto FC, Capone-Neto A, Prist R et al..: Volume replacement with lactated Ringer's or 3% hypertonic saline solution during combined experimental hemorrhagic shock and traumatic brain injury. J. Trauma 60(4), 758-763; discussion 763-1754 (2006).
8. Munar F, Ferrer AM, De Nadal M et al.: Cerebral hemodynamic effects of 7.2% hypertonic saline in patients with head injury and raised intracranial pressure. J. Neurotrauma 17(1), 41-51 (2000).
9. Khanna S, Davis D, Peterson B et al..: Use of hypertonic saline in the treatment of severe refractory posttraumatic intracranial hypertension in pediatric traumatic brain injury. Crit. Care Med. 28(4), 1144-1151 (2000).
10. Samant UB, Mack CD, Koepsell T et al.: Time of hypotension and discharge outcome in children with severe traumatic brain injury. J. Neurotrauma 25(5), 495-502 (2008).
11. Vialet R, Albanese J, Thomachot L et al.: Isovolume hypertonic solutes (sodium chloride or mannitol) in the treatment of refractory posttraumatic intracranial hypertension: 2 ml/kg 7.5% saline is more effective than 2 ml/kg 20% mannitol. Crit. Care Med. 31(6), 1683-1687 (2003).
12. Qureshi AI, Suarez JI, Castro A et al.: Use of hypertonic saline/acetate infusion in treatment of cerebral edema in patients with head trauma: experience at a single center. J. Trauma 47(4), 659-665 (1999).
13. Shackford SR, Bourguignon PR, Wald SL et al..: Hypertonic saline resuscitation of patients with head injury: a prospective, randomized clinical trial. J. Trauma 44(1), 50-58 (1998).
14. Simma B, Burger R, Falk M et al.: A prospective, randomized, and controlled study of fluid management in children with severe head injury: lactated Ringer's solution versus hypertonic saline. Crit. Care Med. 26(7), 1265-1270 (1998).
15. Cooper DJ, Myles PS, McDermott FT et al.: Prehospital hypertonic saline resuscitation of patients with hypotension and severe traumatic brain injury: a randomized controlled trial. JAMA 291(11), 1350-1357 (2004).
16. Brain Trauma Foundation; American Association of Neurological Surgeons; Congress of Neurological Surgeons; Joint Section on Neurotrauma and Critical Care, AANS/CNS; Bratton SL Chestnut RM, Ghajar J et al..: Guidelines for the management of severe traumatic brain injury. II. Hyperosmolar therapy. J. Neurotrauma 24, S14-S20 (2007).
17. Kim JM, Lee ST, Chu K et al.: Systemic transplantation of human adipose stem cells attenuated cerebral inflammation and degeneration in a hemorrhagic stroke model. Brain Res. 1183, 43-50 (2007).
18. Gao J, Prough DS, McAdoo DJ et al.: Transplantation of primed human fetal neural stem cells improves cognitive function in rats after traumatic brain injury. Exp. Neurol. 201(2), 281-292 (2006).
19. Mahmood A, Lu D, Wang L et al..: Treatment of traumatic brain injury in female rats with intravenous administration of bone marrow stromal cells. Neurosurgery 49(5), 1196-1203; discussion 1203-11194 (2001).
20. Lu D, Sanberg PR, Mahmood A et al.: Intravenous administration of human umbilical cord blood reduces neurological deficit in the rat after traumatic brain injury. Cell Transplant. 11(3), 275-281 (2002).
21. Harting MT, Jimenez F, Adams SD et al.: Acute, regional inflammatory response after traumatic brain injury: implications for cellular therapy. Surgery 144(5), 803-813 (2008).
22. Aggarwal S, Pittenger MF: Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 105(4), 1815-1822 (2005).
23. Gastaldello K, Husson C, Dondeyne JP et al..: Cytotoxicity of mononuclear cells as induced by peritoneal dialysis fluids: insight into mechanisms that regulate osmotic stress-related apoptosis. Perit. Dial. Int. 28(6), 655-666 (2008).
24. Lee JW, Ko YE, Lee IH et al.: Osmotic stress induces loss of glutathione and increases the sensitivity to oxidative stress in H9c2 cardiac myocytes. Free Radic. Res. 43(3), 262-271 (2009).
25. Maeno E, Takahashi N, Okada Y: Dysfunction of regulatory volume increase is a key component of apoptosis. FEBS Lett. 580(27), 6513-6517 (2006).
26. Otto NM, Schindler R, Lun A et al.: Hyperosmotic stress enhances cytokine production and decreases phagocytosis in vitro. Crit. Care 12(4), R107 (2008).
27. Harting M, Jimenez F, Pati S et al.: Immunophenotype characterization of rat mesenchymal stromal cells. Cytotherapy 10(3), 243-253 (2008).
28. Lighthall JW: Controlled cortical impact: a new experimental brain injury model. J. Neurotrauma 5(1), 1-15 (1998).
29. Penolazzi L, Lambertini E, Tavanti E et al.: Evaluation of chemokine and cytokine profiles in osteoblast progenitors from umbilical cord blood stem cells by BIO-PLEX technology. Cell Biol. Int. 32(2), 320-325 (2008).
30. Adams SD, Radhakrishnan RS, Helmer KS et al.: Effects of anesthesia on lipopolysaccharide-induced changes in serum cytokines. J. Trauma 65(1), 170-174 (2008).
31. Hayashi T, Kaneko Y, Yu S et al.: Quantitative analyses of matrix metalloproteinase activity after traumatic brain injury in adult rats. Brain Res. 1280, 172-177 (2009).
32. Suehiro E, Fujisawa H, Akimura T et al.: Increased matrix metalloproteinase-9 in blood in association with activation of interleukin-6 after traumatic brain injury: influence of hypothermic therapy. J. Neurotrauma 21(12), 1706-1711 (2004).
33. Truettner JS, Alonso OF, Dalton Dietrich W: Influence of therapeutic hypothermia on matrix metalloproteinase activity after traumatic brain injury in rats. J. Cereb. Blood Flow Metab. 25(11), 1505-1516 (2005).
34. Rios EC, Moretti AI, de Souza HP et al..: Hypertonic saline reduces metalloproteinase expression in liver during pancreatitis. Clin. Exp. Pharmacol. Physiol. (2009) (Epub ahead of print).