Presence of multiple copies of capsulation loci in invasive Haemophilus influenzae type b (Hib) strains in Japan before introduction of the Hib conjugate vaccine

Microbiology and Immunology

Volumn 54, Issue 3, 2010, Pages 160-163

  Ueno, Kentaro ^a   Nishi, Junichiro ^a   Imuta, Naoko ^a   Tokuda, Koichi ^a   Kawano, Yoshifumi ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

Capsular polysaccharide; Haemophilus influenzae type b; Hib conjugate vaccine

Indexed keywords

HAEMOPHILUS INFLUENZAE TYPE B VACCINE;

ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; CAPB GENE; CHILD; CLINICAL ARTICLE; GENE LOCUS; GENE SEQUENCE; HAEMOPHILUS INFLUENZAE TYPE B; HUMAN; INFANT; INFLUENZA; JAPAN; SOUTHERN BLOTTING;

BACTERIAL CAPSULES; BACTERIAL VACCINES; CHILD; CHILD, PRESCHOOL; FEMALE; HAEMOPHILUS INFECTIONS; HAEMOPHILUS INFLUENZAE TYPE B; HUMANS; INFANT; JAPAN; MALE; VACCINES, CONJUGATE; VIRULENCE FACTORS;

HAEMOPHILUS INFLUENZAE SEROTYPE B;

EID: 77649298307     PISSN: 03855600     EISSN: 13480421     Source Type: Journal    
DOI: 10.1111/j.1348-0421.2010.00196.x     Document Type: Article

References (18)

1. Morris S.K., MossW.J., Halsey N. (2008) Haemophilus influenzae type b conjugate vaccine use and effectiveness. Lancet Infect Dis 8: 435-43.
2. Booy R., Heath P.T., Slack M.P., Begg N., Moxon E.R. (1997) Vaccine failures after primary immunisation with Haemophilus influenzae type-b conjugate vaccine without booster. Lancet 349: 1197-202.
3. Schouls L.M., Van Der Ende A., van de Pol I., Schot C., Spanjaard L., Vauterin P.,Wilderbeek D.,Witteveen S. (2005) Increase in genetic diversity of Haemophilus influenzae serotype b (Hib) strains after introduction of Hib vaccination in The Netherlands. J Clin Microbiol 43: 2741-9.
4. Aracil B., Slack M., Perez-Vazquez M., Roman F., Ramsay M., Campos J. (2006) Molecular epidemiology of Haemophilus influenzae type b causing vaccine failures in the United Kingdom. J Clin Microbiol 44: 1645-9.
5. Ramsay M.E., McVernon J., Andrews N.J., Heath P.T., Slack M.P. (2003) Estimating Haemophilus influenzae type b vaccine effectiveness in England and Wales by use of the screening method. J Infect Dis 188: 481-5.
6. Breukels M.A., Jol-van der Zijde E., van Tol M.J., Rijkers G.T. (2002) Concentration and avidity of anti-Haemophilus influenzae type b (Hib) antibodies in serum samples obtained from patients for whom Hib vaccination failed. Clin Infect Dis 34: 191-7.
7. Lee Y.C., Kelly D.F., Yu L.M., Slack M.P., Booy R., Heath P.T., Siegrist C.A., Moxon R.E., Pollard A.J. (2008) Haemophilus influenzae type b vaccine failure in children is associated with inadequate production of high-quality antibody. Clin Infect Dis 46: 186-92.
8. Cerquetti M., Cardines R., Ciofi Degli Atti M.L., Giufre M., Bella A., Sofia T., Mastrantonio P., Slack M. (2005) Presence of multiple copies of the capsulation b locus in invasive Haemophilus influenzae type b (Hib) strains isolated from children with Hib conjugate vaccine failure. J Infect Dis 192: 819-23.
9. Cerquetti M., Cardines R., Giufre M., Sofia T., D'Ambrosio F., Mastrantonio P., Ciofi degli Atti M.L. (2006) Genetic diversity of invasive strains of Haemophilus influenzae type b before and after introduction of the conjugate vaccine in Italy. Clin Infect Dis 43: 317-9.
10. Kroll J.S., Loynds B.M., Moxon E.R. (1991) The Haemophilus influenzae capsulation gene cluster: a compound transposon. Mol Microbiol 5: 1549-60.
11. Noel G.J., Brittingham A., Granato A.A., Mosser D.M. (1996) Effect of amplification of the Cap b locus on complement-mediated bacteriolysis and opsonization of type b Haemophilus influenzae. Infect Immun 64: 4769-75.
12. Schouls L., Van Der Heide H.,Witteveen S., Zomer B., Van Der Ende A., Burger M., Schot C. (2008) Two variants among Haemophilus influenzae serotype b strains with distinct bcs4, hcsA and hcsB genes display differences in expression of the polysaccharide capsule. BMC Microbiol 8: 35.
13. Sunakawa K., Ubukata K., Chiba N., Hasegawa K., Nonoyama M., Iwata S., Akita H., Sato Y. (2008) Childhood bacterial meningitis trends in Japan from 2005 to 2006. Kansenshogaku Zasshi 82: 187-97.
14. Falla T.J., Crook D.W., Brophy L.N., Maskell D., Kroll J.S., Moxon E.R. (1994) PCR for capsular typing of Haemophilus influenzae. J Clin Microbiol 32: 2382-6.
15. Saito M., Umeda A., Yoshida S. (1999) Subtyping of Haemophilus influenzae strains by pulsed-field gel electrophoresis. J Clin Microbiol 37: 2142-7.
16. Tenover F.C., Arbeit R.D., Goering R.V., Mickelsen P.A., Murray B.E., Persing D.H., Swaminathan B. (1995) Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 33: 2233-9.
17. Corn P.G., Anders J., Takala A.K., Kayhty H., Hoiseth S.K. (1993) Genes involved in Haemophilus influenzae type b capsule expression are frequently amplified. J Infect Dis 167: 356-64.
18. Sukupolvi-Petty S., Grass S., St Geme J.W. 3rd (2006) The Haemophilus influenzae Type b hcsA and hcsB gene products facilitate transport of capsular polysaccharide across the outer membrane and are essential for virulence. J Bacteriol 188: 3870-7.