Synthesis and analysis of 2-[211At]-l-phenylalanine and 4-[211At]-l-phenylalanine and their uptake in human glioma cell cultures in-vitro

Applied Radiation and Isotopes

Volumn 68, Issue 6, 2010, Pages 1060-1065

  Meyer, Geerd J ^a   Walte, Almut ^a   Sriyapureddy, Siva R ^a   Grote, Michaela ^a   Krull, Doris ^a   Korkmaz, Zekiye ^a   Knapp, Wolfram H ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Astatine; Cell uptake; Glioblastoma; Halogen exchange; Phenylalanine

Indexed keywords

CELL UPTAKE; GLIOBLASTOMAS; GLIOMA CELLS; HALOGEN EXCHANGE; IN-VITRO; L-PHENYLALANINE; PRODUCTION PATHWAYS; RADIOCHEMICAL YIELD; SEQUENCE ANALYSIS;

ANIMAL CELL CULTURE; ASTATINE; CELL CULTURE;

AMINO ACIDS;

ASTATINE; ASTATINE 2 PHENYLALANINE AT 211; ASTATINE 4 PHENYLALANINE AT 211; BROMINE; CHLORINE; COPPER; FLUORINE; HALOGEN; IODINE; IODINE 2 PHENYLALANINE I 131; IODINE 4 PHENYLALANINE I 131; NUCLEOPHILE; PHENYLALANINE; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG LABELING; DRUG MECHANISM; DRUG PURIFICATION; DRUG SYNTHESIS; DRUG UPTAKE; ELECTROPHILICITY; ELUTION; GLIOMA CELL; HALOGENATION; HUMAN; HUMAN CELL; IN VITRO STUDY; NUCLEOPHILICITY; PRIORITY JOURNAL;

ASTATINE; BRAIN NEOPLASMS; CELL LINE, TUMOR; GLIOMA; HUMANS; ISOTOPE LABELING; PHENYLALANINE; RADIOPHARMACEUTICALS;

EID: 77649276026     PISSN: 09698043     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.apradiso.2009.12.043     Document Type: Article

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