Immunohistochemical expression of the kit protein (cd117) in normal and neoplastic canine testes

Journal of Comparative Pathology

Volumn 142, Issue 2-3, 2010, Pages 213-217

  Grieco, V ^a   Banco, B ^a   Giudice, C ^a   Mosca, F ^a   Finazzi, M ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Dog; Immunohistochemistry; KIT protein; Testis

Indexed keywords

ALKALINE PHOSPHATASE PLACENTA ISOENZYME; STEM CELL FACTOR RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOG; IMMUNOHISTOCHEMISTRY; LEYDIG CELL; LEYDIG CELL TUMOR; NONHUMAN; PRIORITY JOURNAL; SEMINOMA; SERTOLI CELL TUMOR; SPERMATOGONIUM; TESTIS TUMOR; TUMOR CLASSIFICATION;

ANIMALS; DOG DISEASES; DOGS; LEYDIG CELL TUMOR; MALE; PROTO-ONCOGENE PROTEINS C-KIT; SEMINOMA; SERTOLI CELL TUMOR; TESTICULAR NEOPLASMS; TESTIS;

CANIS FAMILIARIS;

EID: 77649273359     PISSN: 00219975     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcpa.2009.07.002     Document Type: Article

References (30)

1. Basciani S., Brama M., Mariani S., De Luca G., Arizzi M., et al. Imatinib mesylate inhibits leydig cell tumor growth: evidence for in vitro and in vivo activity. Cancer Research 2005, 65:1897-1903.
2. Bettini G., Morini M., Marcato P.S. Gastrointestinal spindle cell tumours of the dog: histological and immunohistochemical study. Journal of Comparative Pathology 2003, 129:283-292.
3. Coffey G., Linger R., Dudakia D., Sokal M., Easton D.F. Somatic KIT mutations occur predominantly in seminoma germ cell tumors and are not predictive of bilateral disease: report of 220 tumors and review of literature. Genes, Chromosomes and Cancer 2008, 47:34-42.
4. Cummings O.W., Ulbright T.M., Eble J.N., Roth L.M. Spermatocytic seminoma: an immunohistochemical study. Human Pathology 1994, 25:54-59.
5. Dekker I., Rozeboom T., Delemarre J., Dam A., Oosterhuis J.W. Placental-like alkaline phosphatase and DNA flow cytometry in spermatocytic seminoma. Cancer 1992, 69:993-996.
6. Gaskell T.L., Esnal A., Robinson L.L., Anderson R.A., Saunders P.T. Immunohistochemical profiling of germ cells within the human fetal testis: identification of three subpopulations. Biology of Reproduction 2004, 71:2012-2021.
7. Grieco V., Riccardi E., Rondena M., Ciampi V., Finazzi M. Classical and spermatocytic seminoma in the dog: histochemical and immunohistochemical findings. Journal of Comparative Pathology 2007, 137:41-46.
8. Grieco V., Riccardi E., Veronesi M.C., Giudice C., Finazzi M. Evidence of testicular dysgenesis syndrome in the dog. Theriogenology 2008, 70:53-60.
9. Goddard N.C., McIntyre A., Summersgill B., Gilbert D., Kitazawa S., et al. KIT and RAS signalling pathways in testicular germ cell tumours: new data and a review of the literature. International Journal of Andrology 2007, 30:337-349.
10. Hsu S.M., Raine L., Fanger H. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. Journal of Histochemistry and Cytochemistry 1981, 29:577-580.
11. Hustin J., Gillerot Y., Collette J., Franchimont P. Placental alkaline phosphatase in developing normal and abnormal gonads and in germ-cell tumours. Virchow's Archive A: Pathological Anatomy and Histopathology 1990, 417:67-72.
12. Kennedy P.C., Cullen J.M., Edwards J.F., Goldschmidt M.H., Larsen S., et al. Histological Classification of Tumors of the Genital System of Domestic animals,. World Health Organization International Histological Classification of Tumors of Domestic Animals 1998, Vol. 4:17-18. 2nd Series, Armed Forces Institute of Pathology, Washington D.C.
13. Mauduit C., Hamamah S., Benahmed M. Stem cell factor/c-kit system in spermatogenesis. Human Reproduction Update 1999, 5:535-545.
14. Marconato L., Bettini G., Giacoboni C., Romanelli G., Cesari A., et al. Clinicopathological features and outcome for dogs with mast cell tumors and bone marrow involvement. Journal of Veterinary Internal Medicine 2008, 22:1001-1007.
15. Newman S.J., Mrkonjich L., Walker K.K., Rohrbach B.W. Canine subcutaneous mast cell tumour: diagnosis and prognosis. Journal of Comparative Pathology 2007, 131:231-239.
16. Nurmio M., Toppari J., Zaman F., Andersson A.M., Paranko J., et al. Inhibition of tyrosine kinases PDGFR and c-Kit by imatinib mesylate interferes with postnatal testicular development in the rat. International Journal of Andrology 2007, 30:366-376.
17. Owston M.A., Ramos-Vara J.A. Histologic and immunohistochemical characterization of a testicular mixed germ cell sex cord-stromal tumor and a leydig cell tumor in a dog. Veterinary Pathology 2007, 44:936-943.
18. Paquis-Flucklinger V., Rassoulzadegan M., Michiels J.F. Experimental sertoli cell tumors in the mouse and their progression into a mixed germ cell-sex cord proliferation. American Journal of Pathology 1994, 144:454-459.
19. Prabhu S.M., Meisthich M.L., McLaughlin E.A., Roman S.D., Warne S., et al. Expression of c-kit receptor mRNA and protein in the developing, adult and irradiated rodent testis. Reproduction 2006, 131:489-499.
20. Preziosi R., Morini M., Sarli G. Expression of the KIT protein (CD117) in primary cutaneous mast cell tumours of the dog. Journal of Veterinary Diagnostic Investigation 2004, 16:554-561.
21. Rajpert-De Meyts E., Bartkova Jirina Samson M., Hoei-Hansen C.E., Frydelund-Larsen L., Bartek J., et al. The emerging phenotype of testicular carcinoma in situ germ cell. Acta Pathologica, Microbiologica et Immunologica 2003, 111:267-279.
22. Rajpert-De Meyts E. Developmental model for the pathogenesis of testicular carcinoma in situ: genetic and environmental aspects. Human Reproduction Update 2006, 12:303-323.
23. Reis-Filho J.S., Ricardo S., Gärtner F., Schmitt F.C. Bilateral gonadoblastomas in a dog with mixed gonadal dysgenesis. Journal of Comparative Pathology 2004, 130:29-33.
24. Rothschild G., Sottas C.M., Kissel H., Agosti V., Manova K., et al. A role for kit receptor signaling in leydig cell steroidogenesis. Biology of Reproduction 2003, 69:925-932.
25. Sattler M., Salgia R. Targeting c-kit mutation: basic science to novel therapies. Leukemia Research 2004, 28S1:S11-S20.
26. Stoop H., Honecker F., van de Geijn G.J., Gillis A.J., de Boer M., et al. Stem cell factor as a novel diagnostic marker for early germ cells. Journal of Pathology 2008, 216:43-54.
27. Ulbright T. Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues. Modern Pathology 2005, 18:S61-S79.
28. Wakayama T., Kato Y., Utsumi R., Tsuji A., Iseki S. A time-and cost-saving method of producing rat polyclonal antibodies. Acta Histochemica et Cytochemica 2006, 39:79-87.
29. Wehrle-Hallert B., Imhof B.A. Stem cell factor presentation to c-Kit. Identification of a basolateral targeting domain. Journal of Biological Chemistry 2001, 276:12667-12674.
30. Yoshinaga K., Nishikawa S., Ogawa M., Hayashi S., Kunisada T., et al. Role of c-kit in mouse spermatogenesis: identification of spermatogonia as a specific site of c-kit expression and function. Development 1991, 113:689-699.