Identification and characterisation of an immunodiagnostic marker for cyathostomin developing stage larvae

International Journal for Parasitology

Volumn 40, Issue 3, 2010, Pages 265-275

  McWilliam, Hamish E G ^a   Nisbet, Alasdair J ^a   Dowdall, Samantha M J ^b   Hodgkinson, Jane E ^b   Matthews, Jacqueline B ^a,c  

^a MOREDUN RESEARCH INSTITUTE   (United Kingdom)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Cyathostomins; Gut associated larval antigen; Immunodiagnostic antigen; Larval cyathostominosis

Indexed keywords

CYATHOSTOMIN GUT ASSOCIATED LARVAL ANTIGEN 1; PARASITE ANTIGEN; UNCLASSIFIED DRUG;

ANTIGEN; DISEASE; HORSE; LARVA; LIFE CYCLE; NEMATODE; PARASITE; PATHOLOGY; PROTEIN;

ANTIGEN ANTIBODY COMPLEX; ARTICLE; COLIC; CYATHOSTOMINOSIS; DIARRHEA; DNA LIBRARY; EDEMA; HORSE; LARVAL DEVELOPMENT; LIFE CYCLE; NEMATODE; NEMATODIASIS; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; SERODIAGNOSIS; WEIGHT REDUCTION;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, HELMINTH; CLONING, MOLECULAR; DNA, COMPLEMENTARY; ESCHERICHIA COLI; GENE EXPRESSION; HORSE DISEASES; HORSES; IMMUNOASSAY; LARVA; MOLECULAR SEQUENCE DATA; PARASITOLOGY; SEQUENCE ANALYSIS, DNA; STRONGYLIDA INFECTIONS; STRONGYLOIDEA;

CYATHOSTOMINAE; EQUIDAE; ESCHERICHIA COLI; NEMATODA; VERMES;

EID: 77649272027     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpara.2009.08.004     Document Type: Article

References (37)

1. Abbott J.B., Barrett E.J. The problem of diagnosing tapeworm infections in horses. Equine Vet. J. 2008, 40:5-6.
2. Abbott J.B., Mellor D.J., Barrett E.J., Proudman C.J., Love S. Serological changes observed in horses infected with Anoplocephala perfoliata after treatment with praziquantel and natural reinfection. Vet. Rec. 2008, 162:50-53.
3. Altschul S.F., Gish W., Miller W., Myers E.W., Lipman D.J. Basic local alignment search tool. J. Mol. Biol. 1990, 215:403-410.
4. Barrett E.J., Farlam J., Proudman C.J. Field trial of the efficacy of a combination of ivermectin and praziquantel in horses infected with roundworms and tapeworms. Vet. Rec. 2004, 154:323-325.
5. Bendtsen J.D., Nielsen H., von Heijne G., Brunak S. Improved prediction of signal peptides: SignalP 3.0. J. Mol. Biol. 2004, 340:783-795.
6. Bucknell D.G., Gasser R.B., Beveridge I. The prevalence and epidemiology of gastrointestinal parasites of horses in Victoria, Australia. Int. J. Parasitol. 1995, 25:711-724.
7. Chapman M.R., Kearney M.T., Klei T.R. Equine cyathostome populations: accuracy of species composition estimations. Vet. Parasitol. 2003, 116:15-21.
8. Clark H.J., Kaplan R.M., Matthews J.B., Hodgkinson J.E. Isolation and characterisation of a beta tubulin isotype 2 gene from two species of cyathostomin. Int. J. Parasitol. 2005, 35:349-358.
9. Davidson A.J., Hodgkinson J.E., Proudman C.J., Matthews J.B. Cytokine responses to Cyathostominae larvae in the equine large intestinal wall. Res. Vet. Sci. 2005, 78:169-176.
10. Dowdall S.M., Matthews J.B., Mair T., Murphy D., Love S., Proudman C.J. Antigen-specific IgG(T) responses in natural and experimental Cyathostominae infection in horses. Vet. Parasitol. 2002, 106:225-242.
11. Dowdall S.M., Proudman C.J., Klei T.R., Mair T., Matthews J.B. Characterisation of IgG(T) serum antibody responses to two larval antigen complexes in horses naturally- or experimentally-infected with cyathostomins. Int. J. Parasitol. 2004, 34:101-108.
12. Dowdall S.M., Proudman C.J., Love S., Klei T.R., Matthews J.B. Purification and analyses of the specificity of two putative diagnostic antigens for larval cyathostomin infection in horses. Res. Vet. Sci. 2003, 75:223-229.
13. du Toit N., McGorum B.C., Pemberton A.D., Brown J., Dacre K.J. The involvement of mast cells and mast cell proteinases in the intestinal response to equine cyathostomin infection. Vet. Immunol. Immunopathol. 2007, 115:35-42.
14. Eysker M., Klei T.R. Mucosal larval recovery techniques of cyathostomes: can they be standardized?. Vet. Parasitol. 1999, 85:137-144.
15. Giles C.J., Urquhart K.A., Longstaffe J.A. Larval cyathostomiasis (immature trichonema-induced enteropathy): a report of 15 clinical cases. Equine Vet. J. 1985, 17:196-201.
16. Hodgkinson J.E., Lichtenfels J.R., Mair T.S., Cripps P., Freeman K.L., Ramsey Y.H., Love S., Matthews J.B. A PCR-ELISA for the identification of cyathostomin fourth-stage larvae from clinical cases of larval cyathostominosis. Int. J. Parasitol. 2003, 33:1427-1435.
17. Kaplan R.M. Anthelmintic resistance in nematodes of horses. Vet. Res. 2002, 33:491-507.
18. Kjaer L.N., Lungholt M.M., Nielsen M.K., Olsen S.N., Maddox-Hyttel C. Interpretation of serum antibody response to Anoplocephala perfoliata in relation to parasite burden and faecal egg count. Equine Vet. J. 2007, 39:529-533.
19. Klei T.R., Torbert B.J., Chapman M.R., Ochoa R. Irradiated larval vaccination of ponies against Strongylus vulgaris. J. Parasitol. 1982, 68:561-569.
20. Larkin M.A., Blackshields G., Brown N.P., Chenna R., McGettigan P.A., McWilliam H., Valentin F., Wallace I.M., Wilm A., Lopez R., Thompson J.D., Gibson T.J., Higgins D.G. ClustalW and clustalX version 2.0. Bioinformatics 2007, 23:2947-2948.
21. Lichtenfels J.R., McDonnell A., Love S., Matthews J.B. Nematodes of the tribe Cyathostominea (Strongylidae) collected from horses in Scotland. Comp. Parasitol. 2001, 68:265-269.
22. Lichtenfels J.R., Kharchenko V.A., Dvojnos G.M. Illustrated identification keys to strongylid parasites (Strongylidae: Nematoda) of horses, zebras and asses (Equidae). Vet. Parasitol. 2008, 156:4-161.
23. Love S., Murphy D., Mellor D. Pathogenicity of cyathostome infection. Vet. Parasitol. 1999, 85:113-121.
24. Lyons E.T., Tolliver S.C., Drudge J.H. Historical perspective of cyathostomes: prevalence, treatment and control programs. Vet. Parasitol. 1999, 85:97-111.
25. Lyons E.T., Tolliver S.C., Drudge J.H., Stamper S., Swerczek T.W., Granstrom D.E. A study (1977-1992) of population dynamics of endoparasites featuring benzimidazole-resistant small strongyles (Population S) in Shetland ponies. Vet. Parasitol. 1996, 66:75-86.
26. Marchler-Bauer A., Anderson J.B., Derbyshire M.K., Weese-Scott C., Gonzales N.R., Gwadz M., Hao L.N., He S.Q., Hurwitz D.I., Jackson J.D., Ke Z.X., Krylov D., Lanczycki C.J., Liebert C.A., Liu C.L., Lu F., Lu S.N., Marchler G.H., Mullokandov M., Song J.S., Thanki N., Yamashita R.A., Yin J.J., Zhang D.C., Bryant S.H. CDD: a conserved domain database for interactive domain family analysis. Nucleic Acids Res. 2007, 35:D237-D240.
27. Matthews J.B. An update on cyathostomins: anthelmintic resistance and worm control. Equine Vet. Ed. 2008, 20:552-560.
28. Molento M.B., Antunes J., Bentes R.N., Coles G.C. Anthelmintic resistant nematodes in Brazilian horses. Vet. Rec. 2008, 162:384-385.
29. Murphy D., Love S. The pathogenic effects of experimental cyathostome infections in ponies. Vet. Parasitol. 1997, 70:99-110.
30. Ogbourne C.P. The prevalence, relative abundance and site distribution of nematodes of the subfamily Cyathostominae in horses killed in Britain. J. Helminthol. 1976, 50:203-214.
31. Paul J.W. Equine larval cyathostomosis. Comp. Cont. Educ. Pract. Vet. 1998, 20:509-515.
32. Proudman C.J., Matthews J.B. Control of intestinal parasites in horses. In Pract. 2000, 22:90-97.
33. Reid S.W.J., Mair T.S., Hillyer M.H., Love S. Epidemiologic risk-factors associated with a diagnosis of clinical cyathostomiasis in the horse. Equine Vet. J. 1995, 27:127-130.
34. Reinemeyer C.R., Smith S.A., Gabel A.A., Herd R.P. The prevalence and intensity of internal parasites of horses in the USA. Vet. Parasitol. 1984, 15:75-83.
35. Sambrook J., Fritsch E., Maniatis T. Molecular Cloning: A Laboratory Manual 1989, Cold Harbor Spring Laboratory Press. second ed.
36. Sheoran A., Timoney J.F., Holmes M.A., Karenski S., Crisman M.V. Immunoglobulin isotypes in sera and nasal mucosal secretions and their neonatal transfer and distribution in horses. Am. J. Vet. Res. 2000, 61:1099-1105.
37. Shibui A., Takamoto M., Shi Y., Komiyama A., Sugane K. Cloning and characterization of a novel gene encoding keratin-like protein from nematode Nippostrongylus brasiliensis. BBA Gene Struct. Expression 2001, 1522:59-61.