Curcumin inhibits hepatitis C virus replication via suppressing the Akt-SREBP-1 pathway

FEBS Letters

Volumn 584, Issue 4, 2010, Pages 707-712

  Kim, KyeongJin ^a   Kim, Kook Hwan ^a   Kim, Hye Young ^a   Cho, Hyun Kook ^a   Sakamoto, Naoya ^b   Cheong, JaeHun ^a  

^a Pusan National University   (South Korea)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Akt; Curcumin; HCV; NS5A; SREBP 1

Indexed keywords

ALPHA INTERFERON; CURCUMIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN KINASE B; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG IDENTIFICATION; DRUG POTENCY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REPRESSION; GENE EXPRESSION REGULATION; HEPATITIS C; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; VIRUS REPLICATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIVIRAL AGENTS; CELL LINE, TUMOR; CURCUMIN; DRUG SYNERGISM; GENE EXPRESSION REGULATION, VIRAL; HEPACIVIRUS; HUMANS; INTERFERON-ALPHA; NF-KAPPA B; PROTO-ONCOGENE PROTEINS C-AKT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSCRIPTION FACTOR RELA; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

ADENOVIRIDAE; COXSACKIEVIRUS; CURCUMA LONGA; HEPATITIS C VIRUS; HUMAN IMMUNODEFICIENCY VIRUS; ORTHOMYXOVIRIDAE;

EID: 77649270720     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2009.12.019     Document Type: Article

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