A stretch of 17 amino acids in the prosaposin C terminus is critical for its binding to sortilin and targeting to lysosomes

Journal of Histochemistry and Cytochemistry

Volumn 58, Issue 3, 2010, Pages 287-300

  Yuan, Libin ^a   Morales, Carlos R ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Lysosome; Prosaposin; Saposin; Sortilin

Indexed keywords

AMINO ACID; CYSTEINE; PROSAPOSIN; SORTILIN; SPHINGOLIPID ACTIVATOR PROTEIN; TRYPTOPHAN;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; HYDROPHILICITY; IMMUNOPRECIPITATION; LYSOSOME; NONHUMAN; PH; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; HYDROGEN-ION CONCENTRATION; LYSOSOMES; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN TRANSPORT; SAPOSINS;

EID: 77649264384     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1369/jhc.2009.955203     Document Type: Article

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