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Volumn 17, Issue 3, 2010, Pages 354-362

Construction of recombinant attenuated Salmonella enterica serovar typhimurium vaccine vector strains for safety in newborn and infant mice

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT ATTENUATED SALMONELLA ENTERICA SEROVAR TYPHIMURIUM VACCINE; RECOMBINANT VACCINE; SALMONELLOSIS VACCINE; UNCLASSIFIED DRUG;

EID: 77649262349     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00412-09     Document Type: Article
Times cited : (32)

References (46)
  • 1
    • 0031882679 scopus 로고    scopus 로고
    • Identification of the fucose synthetase gene in the colanic acid gene cluster of Escherichia coli K-12
    • Andrianopoulos, K., L. Wang, and P. R. Reeves. 1998. Identification of the fucose synthetase gene in the colanic acid gene cluster of Escherichia coli K-12. J. Bacteriol. 180:998-1001.
    • (1998) J. Bacteriol , vol.180 , pp. 998-1001
    • Andrianopoulos, K.1    Wang, L.2    Reeves, P.R.3
  • 2
    • 0023664923 scopus 로고
    • Ferric uptake regulation protein acts as a repressor, employing iron (II) as a cofactor to bind the operator of an iron transport operon in Escherichia coli
    • Bagg, A., and J. B. Neilands. 1987. Ferric uptake regulation protein acts as a repressor, employing iron (II) as a cofactor to bind the operator of an iron transport operon in Escherichia coli. Biochemistry 26:5471-5477.
    • (1987) Biochemistry , vol.26 , pp. 5471-5477
    • Bagg, A.1    Neilands, J.B.2
  • 3
    • 84873799110 scopus 로고
    • Studies on lysogenesis. I. The mode of phage liberation by lysogenic Escherichia coli
    • Bertani, G. 1951. Studies on lysogenesis. I. The mode of phage liberation by lysogenic Escherichia coli. J. Bacteriol. 62:293-300.
    • (1951) J. Bacteriol , vol.62 , pp. 293-300
    • Bertani, G.1
  • 4
    • 46449135736 scopus 로고    scopus 로고
    • Presence of wild-type and attenuated Salmonella enterica strains in brain tissues following inoculation of mice by different routes
    • Bollen, W. S., B. M. Gunn, H. Mo, M. K. Lay, and R. Curtiss III. 2008. Presence of wild-type and attenuated Salmonella enterica strains in brain tissues following inoculation of mice by different routes. Infect. Immun. 76:3268-3272.
    • (2008) Infect. Immun , vol.76 , pp. 3268-3272
    • Bollen, W.S.1    Gunn, B.M.2    Mo, H.3    Lay, M.K.4    Curtiss III, R.5
  • 5
    • 0026089558 scopus 로고
    • Mutations at rfc or pmi attenuate Salmonella typhimurium virulence for mice
    • Collins, L. V., S. Attridge, and J. Hackett. 1991. Mutations at rfc or pmi attenuate Salmonella typhimurium virulence for mice. Infect. Immun. 59: 1079-1085.
    • (1991) Infect. Immun , vol.59 , pp. 1079-1085
    • Collins, L.V.1    Attridge, S.2    Hackett, J.3
  • 6
    • 0030068981 scopus 로고    scopus 로고
    • Salmonella enteritidis agfBAC operon encoding thin, aggregative fimbriae
    • Collinson, S. K., S. C. Clouthier, J. L. Doran, P. A. Banser, and W. W. Kay. 1996. Salmonella enteritidis agfBAC operon encoding thin, aggregative fimbriae. J. Bacteriol. 178:662-667.
    • (1996) J. Bacteriol , vol.178 , pp. 662-667
    • Collinson, S.K.1    Clouthier, S.C.2    Doran, J.L.3    Banser, P.A.4    Kay, W.W.5
  • 7
    • 84882870003 scopus 로고    scopus 로고
    • Curtiss, R., III. 2005. Antigen delivery systems: development of live recombinant attenuated bacterial antigen and DNA vaccine delivery vector vaccines, p. 1009-1037. In J. Mestecky, M. E. Lamm, W. Strober, J. Bienenstock, J. R. McGhee, and L. Mayer (ed.), Mucosal immunology, 3rd ed., 1. Elsevier Academic Press, Amsterdam, The Netherlands.
    • Curtiss, R., III. 2005. Antigen delivery systems: development of live recombinant attenuated bacterial antigen and DNA vaccine delivery vector vaccines, p. 1009-1037. In J. Mestecky, M. E. Lamm, W. Strober, J. Bienenstock, J. R. McGhee, and L. Mayer (ed.), Mucosal immunology, 3rd ed., vol. 1. Elsevier Academic Press, Amsterdam, The Netherlands.
  • 8
    • 78651195950 scopus 로고
    • Chromosomal aberrations associated with mutations to bacteriophage resistance in Escherichia coli
    • Curtiss, R., III. 1965. Chromosomal aberrations associated with mutations to bacteriophage resistance in Escherichia coli. J. Bacteriol. 89:28-40.
    • (1965) J. Bacteriol , vol.89 , pp. 28-40
    • Curtiss III, R.1
  • 9
    • 0030293725 scopus 로고    scopus 로고
    • Nonrecombinant and recombinant avirulent Salmonella vaccines for poultry
    • Curtiss, R., III, and J. O. Hassan. 1996. Nonrecombinant and recombinant avirulent Salmonella vaccines for poultry. Vet. Immunol. Immunopathol. 54:365-372.
    • (1996) Vet. Immunol. Immunopathol , vol.54 , pp. 365-372
    • Curtiss III, R.1    Hassan, J.O.2
  • 10
    • 0023491110 scopus 로고
    • Salmonella typhimurium deletion mutants lacking adenylate cyclase and cyclic AMP receptor protein are avirulent and immunogenic
    • Curtiss, R., III, and S. M. Kelly. 1987. Salmonella typhimurium deletion mutants lacking adenylate cyclase and cyclic AMP receptor protein are avirulent and immunogenic. Infect. Immun. 55:3035-3043.
    • (1987) Infect. Immun , vol.55 , pp. 3035-3043
    • Curtiss III, R.1    Kelly, S.M.2
  • 11
    • 85151199006 scopus 로고    scopus 로고
    • Induction of host immune responses using Salmonella-vectored vaccines
    • K. A. Brogden, N. Cornick, T. B. Stanton, Q. Zhang, L. K. Nolan, and M. J. Wannemuehler ed, 4th ed. ASM Press, Washington, DC
    • Curtiss, R., III, X. Zhang, S. Y. Wanda, H. Y. Kang, V. Konjufca, Y. Li, B. Gunn, S. Wang, G. Scarpellini, and I. S. Lee. 2007. Induction of host immune responses using Salmonella-vectored vaccines, p. 297-313. In K. A. Brogden, N. Cornick, T. B. Stanton, Q. Zhang, L. K. Nolan, and M. J. Wannemuehler (ed.), Virulence mechanisms of bacterial pathogens, 4th ed. ASM Press, Washington, DC.
    • (2007) Virulence mechanisms of bacterial pathogens , pp. 297-313
    • Curtiss III, R.1    Zhang, X.2    Wanda, S.Y.3    Kang, H.Y.4    Konjufca, V.5    Li, Y.6    Gunn, B.7    Wang, S.8    Scarpellini, G.9    Lee, I.S.10
  • 12
    • 0003115701 scopus 로고
    • Nonrecombinant and recombinant avirulent Salmonella live vaccines for poultry
    • L. C. Blankenship, J. S. Bailey, N. A. Cox, S. E. Craven, R. J. Meinersmann, and N. S. Stern ed, Academic Press, Inc, San Diego, CA
    • Curtiss, R., III, S. B. Porter, M. Munson, S. A. Tinge, J. O. Hassan, C. Gentry-Weeks, and S. M. Kelly. 1991. Nonrecombinant and recombinant avirulent Salmonella live vaccines for poultry, p. 169-198. In L. C. Blankenship, J. S. Bailey, N. A. Cox, S. E. Craven, R. J. Meinersmann, and N. S. Stern (ed.), Colonization control of human bacterial enteropathogens in poultry. Academic Press, Inc., San Diego, CA.
    • (1991) Colonization control of human bacterial enteropathogens in poultry , pp. 169-198
    • Curtiss III, R.1    Porter, S.B.2    Munson, M.3    Tinge, S.A.4    Hassan, J.O.5    Gentry-Weeks, C.6    Kelly, S.M.7
  • 14
    • 0034120119 scopus 로고    scopus 로고
    • Exopolysaccharide production is required for development of Escherichia coli K-12 biofilm architecture
    • Danese, P. N., L. A. Pratt, and R. Kolter. 2000. Exopolysaccharide production is required for development of Escherichia coli K-12 biofilm architecture. J. Bacteriol. 182:3593-3596.
    • (2000) J. Bacteriol , vol.182 , pp. 3593-3596
    • Danese, P.N.1    Pratt, L.A.2    Kolter, R.3
  • 16
    • 0011736531 scopus 로고
    • Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent
    • Fields, P. I., R. V. Swanson, C. G. Haidaris, and F. Heffron. 1986. Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent. Proc. Natl. Acad. Sci. U. S. A. 83:5189-5193.
    • (1986) Proc. Natl. Acad. Sci. U. S. A , vol.83 , pp. 5189-5193
    • Fields, P.I.1    Swanson, R.V.2    Haidaris, C.G.3    Heffron, F.4
  • 17
    • 0024445956 scopus 로고
    • Virulence and vaccine potential of phoP mutants of Salmonella typhimurium
    • Galán, J. E., and R. Curtiss III. 1989. Virulence and vaccine potential of phoP mutants of Salmonella typhimurium. Microb. Pathog. 6:433-443.
    • (1989) Microb. Pathog , vol.6 , pp. 433-443
    • Galán, J.E.1    Curtiss III, R.2
  • 18
    • 0025110368 scopus 로고
    • Cloning and characterization of the asd gene of Salmonella typhimurium: Use in stable maintenance of recombinant plasmids in Salmonella vaccine strains
    • Galán, J. E., K. Nakayama, and R. Curtiss III. 1990. Cloning and characterization of the asd gene of Salmonella typhimurium: use in stable maintenance of recombinant plasmids in Salmonella vaccine strains. Gene 94:29-35.
    • (1990) Gene , vol.94 , pp. 29-35
    • Galán, J.E.1    Nakayama, K.2    Curtiss III, R.3
  • 19
    • 0030921542 scopus 로고    scopus 로고
    • A secreted effector protein of Salmonella dublin is translocated into eukaryotic cells and mediates inflammation and fluid secretion in infected ileal mucosa
    • Galyov, E. E., M. W. Wood, R. Rosqvist, P. B. Mullan, P. R. Watson, S. Hedges, and T. S. Wallis. 1997. A secreted effector protein of Salmonella dublin is translocated into eukaryotic cells and mediates inflammation and fluid secretion in infected ileal mucosa. Mol. Microbiol. 25:903-912.
    • (1997) Mol. Microbiol , vol.25 , pp. 903-912
    • Galyov, E.E.1    Wood, M.W.2    Rosqvist, R.3    Mullan, P.B.4    Watson, P.R.5    Hedges, S.6    Wallis, T.S.7
  • 20
    • 0027485163 scopus 로고
    • Role of acid tolerance response genes in Salmonella typhimurium virulence
    • Garcia-del Portillo, F., J. W. Foster, and B. B. Finlay. 1993. Role of acid tolerance response genes in Salmonella typhimurium virulence. Infect. Immun. 61:4489-4492.
    • (1993) Infect. Immun , vol.61 , pp. 4489-4492
    • Garcia-del Portillo, F.1    Foster, J.W.2    Finlay, B.B.3
  • 21
    • 0026088437 scopus 로고
    • Lipid A-like molecules that antagonize the effects of endotoxins on human monocytes
    • Golenbock, D. T., R. Y. Hampton, N. Qureshi, K. Takayama, and C. R. H. Raetz. 1991. Lipid A-like molecules that antagonize the effects of endotoxins on human monocytes. J. Biol. Chem. 266:19490-19498.
    • (1991) J. Biol. Chem , vol.266 , pp. 19490-19498
    • Golenbock, D.T.1    Hampton, R.Y.2    Qureshi, N.3    Takayama, K.4    Raetz, C.R.H.5
  • 22
    • 0343575172 scopus 로고
    • Salmonella typhimurium phoP virulence gene is a transcriptional regulator
    • Groisman, E. A., E. Chiao, C. J. Lipps, and F. Heffron. 1989. Salmonella typhimurium phoP virulence gene is a transcriptional regulator. Proc. Natl. Acad. Sci. U. S. A. 86:7077-7081.
    • (1989) Proc. Natl. Acad. Sci. U. S. A , vol.86 , pp. 7077-7081
    • Groisman, E.A.1    Chiao, E.2    Lipps, C.J.3    Heffron, F.4
  • 23
    • 0029818614 scopus 로고    scopus 로고
    • The role of fur in the acid tolerance response of Salmonella typhimurium is physiologically and genetically separable from its role in iron acquisition
    • Hall, H. K., and J. W. Foster. 1996. The role of fur in the acid tolerance response of Salmonella typhimurium is physiologically and genetically separable from its role in iron acquisition. J. Bacteriol. 178:5683-5691.
    • (1996) J. Bacteriol , vol.178 , pp. 5683-5691
    • Hall, H.K.1    Foster, J.W.2
  • 24
    • 0027945734 scopus 로고
    • Development and evaluation of an experimental vaccination program using a live avirulent Salmonella typhimurium strain to protect immunized chickens against challenge with homologous and heterologous Salmonella serotypes
    • Hassan, J. O., and R. Curtiss III. 1994. Development and evaluation of an experimental vaccination program using a live avirulent Salmonella typhimurium strain to protect immunized chickens against challenge with homologous and heterologous Salmonella serotypes. Infect. Immun. 62:5519-5527.
    • (1994) Infect. Immun , vol.62 , pp. 5519-5527
    • Hassan, J.O.1    Curtiss III, R.2
  • 25
    • 0020789450 scopus 로고
    • Aberrant migration of lipopolysaccharide in sodium dodecyl sulfate/polyacrylamide gel electrophoresis
    • Hitchcock, P. J. 1983. Aberrant migration of lipopolysaccharide in sodium dodecyl sulfate/polyacrylamide gel electrophoresis. Eur. J. Biochem. 133: 685-688.
    • (1983) Eur. J. Biochem , vol.133 , pp. 685-688
    • Hitchcock, P.J.1
  • 26
    • 0017668449 scopus 로고
    • L-Arabinose transport and the L-arabinose binding protein of Escherichia coli
    • Hogg, R. W. 1977. L-Arabinose transport and the L-arabinose binding protein of Escherichia coli. J. Supramol. Struct. 6:411-417.
    • (1977) J. Supramol. Struct , vol.6 , pp. 411-417
    • Hogg, R.W.1
  • 27
    • 0036134762 scopus 로고    scopus 로고
    • Transduction-mediated transfer of unmarked deletion and point mutations through use of counterselectable suicide vectors
    • Kang, H. Y., C. M. Dozois, S. A. Tinge, T. H. Lee, and R. Curtiss III. 2002. Transduction-mediated transfer of unmarked deletion and point mutations through use of counterselectable suicide vectors. J. Bacteriol. 184:307-312.
    • (2002) J. Bacteriol , vol.184 , pp. 307-312
    • Kang, H.Y.1    Dozois, C.M.2    Tinge, S.A.3    Lee, T.H.4    Curtiss III, R.5
  • 28
    • 0036128741 scopus 로고    scopus 로고
    • Immune responses to recombinant pneumococcal PspA antigen delivered by live attenuated Salmonella enterica serovar Typhimurium vaccine
    • Kang, H. Y., J. Srinivasan, and R. Curtiss III. 2002. Immune responses to recombinant pneumococcal PspA antigen delivered by live attenuated Salmonella enterica serovar Typhimurium vaccine. Infect. Immun. 70:1739-1749.
    • (2002) Infect. Immun , vol.70 , pp. 1739-1749
    • Kang, H.Y.1    Srinivasan, J.2    Curtiss III, R.3
  • 29
    • 48249135779 scopus 로고    scopus 로고
    • Regulated programmed lysis of recombinant Salmonella in host tissues to release protective antigens and confer biological containment
    • Kong, W., S. Y. Wanda, X. Zhang, W. Bollen, S. A. Tinge, K. L. Roland, and R. Curtiss III. 2008. Regulated programmed lysis of recombinant Salmonella in host tissues to release protective antigens and confer biological containment. Proc. Natl. Acad. Sci. U. S. A. 105:9361-9366.
    • (2008) Proc. Natl. Acad. Sci. U. S. A , vol.105 , pp. 9361-9366
    • Kong, W.1    Wanda, S.Y.2    Zhang, X.3    Bollen, W.4    Tinge, S.A.5    Roland, K.L.6    Curtiss III, R.7
  • 30
    • 50449147866 scopus 로고
    • Transduction of linked genetic characters of the host by bacteriophage P1
    • Lennox, E. S. 1955. Transduction of linked genetic characters of the host by bacteriophage P1. Virology 1:190-206.
    • (1955) Virology , vol.1 , pp. 190-206
    • Lennox, E.S.1
  • 31
    • 58849132311 scopus 로고    scopus 로고
    • Evaluation of new generation Salmonella enterica serovar Typhimurium vaccines with regulated delayed attenuation to induce immune responses against PspA
    • Li, Y., S. Wang, G. Scarpellini, B. Gunn, W. Xin, S. Y. Wanda, K. L. Roland, and R. Curtiss III. 2009. Evaluation of new generation Salmonella enterica serovar Typhimurium vaccines with regulated delayed attenuation to induce immune responses against PspA. Proc. Natl. Acad. Sci. U. S. A. 106:593-598.
    • (2009) Proc. Natl. Acad. Sci. U. S. A , vol.106 , pp. 593-598
    • Li, Y.1    Wang, S.2    Scarpellini, G.3    Gunn, B.4    Xin, W.5    Wanda, S.Y.6    Roland, K.L.7    Curtiss III, R.8
  • 32
    • 0019407288 scopus 로고
    • Identification of the AraE transport protein of Escherichia coli
    • MacPherson, A. J., M. C. Jones-Mortimer, and P. J. Henderson. 1981. Identification of the AraE transport protein of Escherichia coli. Biochem. J. 196:269-283.
    • (1981) Biochem. J , vol.196 , pp. 269-283
    • MacPherson, A.J.1    Jones-Mortimer, M.C.2    Henderson, P.J.3
  • 33
    • 0003582512 scopus 로고
    • A two-component regulatory system (phoP phoQ) controls Salmonella typhimurium virulence
    • Miller, S. I., A. M. Kukral, and J. J. Mekalanos. 1989. A two-component regulatory system (phoP phoQ) controls Salmonella typhimurium virulence. Proc. Natl. Acad. Sci. U. S. A. 86:5054-5058.
    • (1989) Proc. Natl. Acad. Sci. U. S. A , vol.86 , pp. 5054-5058
    • Miller, S.I.1    Kukral, A.M.2    Mekalanos, J.J.3
  • 34
    • 0023769894 scopus 로고
    • + expression-cloning vector: Stable maintenance and high level expression of cloned genes in a Salmonella vaccine strain
    • + expression-cloning vector: stable maintenance and high level expression of cloned genes in a Salmonella vaccine strain. Biotechnology (NY) 6:693-697.
    • (1988) Biotechnology (NY) , vol.6 , pp. 693-697
    • Nakayama, K.1    Kelly, S.M.2    Curtiss III, R.3
  • 35
    • 0032564446 scopus 로고    scopus 로고
    • SopB, a protein required for virulence of Salmonella dublin, is an inositol phosphate phosphatase
    • Norris, F. A., M. P. Wilson, T. S. Wallis, E. E. Galyov, and P. W. Majerus. 1998. SopB, a protein required for virulence of Salmonella dublin, is an inositol phosphate phosphatase. Proc. Natl. Acad. Sci. U. S. A. 95:14057-14059.
    • (1998) Proc. Natl. Acad. Sci. U. S. A , vol.95 , pp. 14057-14059
    • Norris, F.A.1    Wilson, M.P.2    Wallis, T.S.3    Galyov, E.E.4    Majerus, P.W.5
  • 36
    • 0036117936 scopus 로고    scopus 로고
    • Biofilm formation and interaction with the surfaces of gallstones by Salmonella spp
    • Prouty, A. M., W. H. Schwesinger, and J. S. Gunn. 2002. Biofilm formation and interaction with the surfaces of gallstones by Salmonella spp. Infect. Immun. 70:2640-2649.
    • (2002) Infect. Immun , vol.70 , pp. 2640-2649
    • Prouty, A.M.1    Schwesinger, W.H.2    Gunn, J.S.3
  • 37
    • 0033167074 scopus 로고    scopus 로고
    • Construction and evaluation of a Δcya Δcrp Salmonella typhimurium strain expressing avian pathogenic Escherichia coli O78 LPS as a vaccine to prevent airsacculitis in chickens
    • Roland, K., R. Curtiss III, and D. Sizemore. 1999. Construction and evaluation of a Δcya Δcrp Salmonella typhimurium strain expressing avian pathogenic Escherichia coli O78 LPS as a vaccine to prevent airsacculitis in chickens. Avian Dis. 43:429-441.
    • (1999) Avian Dis , vol.43 , pp. 429-441
    • Roland, K.1    Curtiss III, R.2    Sizemore, D.3
  • 38
    • 0017100269 scopus 로고
    • Bacteriophage-specific DNA-binding proteins in P22-lysogenic and in P22-infected Salmonella typhimurium
    • Schumann, W., E. Lindenblatt, and E. G. Bade. 1976. Bacteriophage-specific DNA-binding proteins in P22-lysogenic and in P22-infected Salmonella typhimurium. J. Virol. 20:334-338.
    • (1976) J. Virol , vol.20 , pp. 334-338
    • Schumann, W.1    Lindenblatt, E.2    Bade, E.G.3
  • 39
    • 0023127806 scopus 로고
    • Universal chemical assay for the detection and determination of siderophores
    • Schwyn, B., and J. B. Neilands. 1987. Universal chemical assay for the detection and determination of siderophores. Anal. Biochem. 160:47-56.
    • (1987) Anal. Biochem , vol.160 , pp. 47-56
    • Schwyn, B.1    Neilands, J.B.2
  • 40
    • 77649252640 scopus 로고    scopus 로고
    • Shi, H., S. Wang, K. L. Roland, B. M. Gunn, and R. Curtiss III. 2010. Immunogenicity of a live recombinant Salmonella enterica serovar Typhimurium vaccine expressing pspA in neonates and infant mice born from naïve and immunized mothers. Clin. Vaccine Immunol. 17:363-371.
    • Shi, H., S. Wang, K. L. Roland, B. M. Gunn, and R. Curtiss III. 2010. Immunogenicity of a live recombinant Salmonella enterica serovar Typhimurium vaccine expressing pspA in neonates and infant mice born from naïve and immunized mothers. Clin. Vaccine Immunol. 17:363-371.
  • 41
    • 0032728550 scopus 로고    scopus 로고
    • Escherichia coli msbB gene as a virulence factor and a therapeutic target
    • Somerville, J. E., Jr., L. Cassiano, and R. P. Darveau. 1999. Escherichia coli msbB gene as a virulence factor and a therapeutic target. Infect. Immun. 67:6583-6590.
    • (1999) Infect. Immun , vol.67 , pp. 6583-6590
    • Somerville Jr., J.E.1    Cassiano, L.2    Darveau, R.P.3
  • 43
    • 0029779295 scopus 로고    scopus 로고
    • Organization of the Escherichia coli K-12 gene cluster responsible for production of the extracellular polysaccharide colanic acid
    • Stevenson, G., K. Andrianopoulos, M. Hobbs, and P. R. Reeves. 1996. Organization of the Escherichia coli K-12 gene cluster responsible for production of the extracellular polysaccharide colanic acid. J. Bacteriol. 178:4885-4893.
    • (1996) J. Bacteriol , vol.178 , pp. 4885-4893
    • Stevenson, G.1    Andrianopoulos, K.2    Hobbs, M.3    Reeves, P.R.4
  • 44
    • 0018894635 scopus 로고
    • Accumulation of ppGpp in a relA mutant of Escherichia coli during amino acid starvation
    • Török, I., and C. Kari. 1980. Accumulation of ppGpp in a relA mutant of Escherichia coli during amino acid starvation. J. Biol. Chem. 255:3838-3840.
    • (1980) J. Biol. Chem , vol.255 , pp. 3838-3840
    • Török, I.1    Kari, C.2
  • 45
    • 46449130050 scopus 로고    scopus 로고
    • Analysis of type II secretion of recombinant pneumococcal PspA and PspC in a Salmonella enterica serovar Typhimurium vaccine with regulated delayed antigen synthesis
    • Xin, W., S. Y. Wanda, Y. Li, S. Wang, H. Mo, and R. Curtiss III. 2008. Analysis of type II secretion of recombinant pneumococcal PspA and PspC in a Salmonella enterica serovar Typhimurium vaccine with regulated delayed antigen synthesis. Infect. Immun. 76:3241-3254.
    • (2008) Infect. Immun , vol.76 , pp. 3241-3254
    • Xin, W.1    Wanda, S.Y.2    Li, Y.3    Wang, S.4    Mo, H.5    Curtiss III, R.6
  • 46
    • 0030729230 scopus 로고    scopus 로고
    • Characterization and immunogenicity of Salmonella typhimurium SL1344 and UK-1 Δcrp and Δcdt deletion mutants
    • Zhang, X., S. M. Kelly, W. S. Bollen, and R. Curtiss III. 1997. Characterization and immunogenicity of Salmonella typhimurium SL1344 and UK-1 Δcrp and Δcdt deletion mutants. Infect. Immun. 65:5381-5387.
    • (1997) Infect. Immun , vol.65 , pp. 5381-5387
    • Zhang, X.1    Kelly, S.M.2    Bollen, W.S.3    Curtiss III, R.4


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