Discrimination of carcinogens by hepatic transcript profiling in rats following 28-day administration

Cancer Informatics

Volumn 7, Issue , 2009, Pages 253-269

  Matsumoto, Hiroshi ^a   Yakabe, Yoshikuni ^a   Saito, Koichi ^b   Sumida, Kayo ^b   Sekijima, Masaru ^c   Nakayama, Koji ^c   Miyaura, Hideki ^a   Saito, Fumiyo ^a   Otsuka, Masanori ^a   Shirai, Tomoyuki ^d  

^a CHEMICALS EVALUATION AND RESEARCH INSTITUTE   (Japan)

^b SUMITOMO CHEMICAL CO LTD   (Japan)

^c MITSUBISHI CHEMICAL CORPORATION   (Japan)

^d NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

Author keywords

Carcinogenicity; Cluster analysis; Hepatocarcinogen; Microarray; Mutagenicity; Toxicogenomics

Indexed keywords

CARCINOGEN; ESTROGENIC CARCINOGEN; HEPATOCARCINOGEN; MUTAGENIC AGENT; UNCLASSIFIED DRUG; ESTRONE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PROTEIN BAX; PROTEIN P53; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 6;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CARCINOGENICITY; CLUSTER ANALYSIS; CONTROLLED STUDY; GENE EXPRESSION; GENOTOXICITY; MALE; NONHUMAN; RAT; TARGET ORGAN; TOXICITY TESTING; ABCB1B GENE; BAX GENE; BTG2 GENE; FISCHER 344 RAT; GENE; LIVER; MGMT GENE; MICROARRAY ANALYSIS; MUTAGENICITY; SIGNAL TRANSDUCTION; TNFRSF6 GENE; TUMOR SUPPRESSOR GENE;

EID: 77649254737     PISSN: 11769351     EISSN: 11769351     Source Type: Journal    
DOI: 10.4137/cin.s3229     Document Type: Article

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