Gene polymorphisms of ACE and the angiotensin receptor AT2R1 influence serum ACE levels in sarcoidosis

Sarcoidosis Vasculitis and Diffuse Lung Diseases

Volumn 26, Issue 2, 2009, Pages 139-146

  Biller, H ^a   Ruprecht, B ^b   Gaede, K I ^c   Muller Quernheim J ^d   Zissel, G ^d  

^a FRAUNHOFER INSTITUTE FOR TOXICOLOGY AND EXPERIMENTAL MEDICINE   (Germany)

^b Medical Dept I   (Germany)

^c RESEARCH CENTER BORSTEL   (Germany)

^d UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Angiotensin II type 1 receptor; Angiotensin converting enzyme; Gene polymorphism; Sarcoidosis

Indexed keywords

ANGIOTENSIN 2 RECEPTOR; DIPEPTIDYL CARBOXYPEPTIDASE;

ADULT; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DNA POLYMORPHISM; ENZYME KINETICS; FEMALE; GENE DELETION; GENE INSERTION; GENE MUTATION; GENETIC SUSCEPTIBILITY; HETEROZYGOTE; HOMOZYGOTE; HUMAN; LUNG SARCOIDOSIS; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ADULT; DNA; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; PEPTIDYL-DIPEPTIDASE A; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; RECEPTOR, ANGIOTENSIN, TYPE 2; SARCOIDOSIS;

EID: 77649253063     PISSN: 11240490     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Lieberman J. Elevation of serum angiotensin-converting-enzyme (ACE) level in sarcoidosis. Am J Med 1975; 59: 365-72.
2. Lieberman J, Schleissner LA, Nosal A, Sastre A, Mishkin FS. Clinical correlations of serum angiotensin-converting enzyme (ACE) in sarcoidosis. A longitudinal study of serum ACE, 67gallium scans, chest roentgenograms, and pulmonary function. Chest 1983; 84: 522-8.
3. Rigat B, Hubert C, Alhenc-Gelas F, Cambien F, Corvol P, Soubrier F. An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 1990; 86: 1343-6.
4. Arbustini E, Grasso M, Leo G, et al. Polymorphism of angiotensinconverting enzyme gene in sarcoidosis. Am J Respir Crit Care Med 1996;153: 851-4.
5. McGrath DS, Foley PJ, Petrek M, et al. Ace gene I/D polymorphism and sarcoidosis pulmonary disease severity. Am J Respir Crit Care Med 2001; 164: 197-201.
6. Tomita H, Ina Y, Sugiura Y, et al. Polymorphism in the angiotensin-converting enzyme (ACE) gene and sarcoidosis. Am J Respir Crit Care Med 1997; 156: 255-9.
7. Furuya K, Yamaguchi E, Itoh A, et al. Deletion polymorphism in the angiotensin I converting enzyme (ACE) gene as a genetic risk factor for sarcoidosis. Thorax 1996; 51: 777-80.
8. Rybicki BA, Maliarik MJ, Major M, Popovich J Jr., Iannuzzi MC. Epidemiology, demographics, and genetics of sarcoidosis. Semin Respir Infect 1998; 13: 166-73.
9. Schurmann M, Reichel P, Muller-Myhsok B, et al. Angiotensin-converting enzyme (ACE) gene polymorphisms and familial occurrence of sarcoidosis. J Intern Med 2001; 249: 77-83.
10. Pietinalho A, Furuya K, Yamaguchi E, Kawakami Y, Selroos O. The angiotensin-converting enzyme DD gene is associated with poor prognosis in Finnish sarcoidosis patients. Eur Respir J 1999; 13: 723-6.
11. Takayanagi R, Ohnaka K, Sakai Y, et al. Molecular cloning, sequence analysis and expression of a cDNA encoding human type-1 angiotensin II receptor. Biochem Biophys Res Commun 1992; 183: 910-6.
12. Takemoto Y, Sakatani M, Takami S, et al. Association between angiotensin II receptor gene polymorphism and serum angiotensin converting enzyme (SACE) activity in patients with sarcoidosis. Thorax 1998; 53: 459-62.
13. Gardemann A, Nguyen QD, Humme J, et al. Angiotensin II type 1 receptor A1166C gene polymorphism. Absence of an association with the risk of coronary artery disease and myocardial infarction and of a synergistic effect with angiotensin-converting enzyme gene polymorphism on the risk of these diseases. Eur Heart J 1998; 19: 1657-65.
14. Tiret L, Bonnardeaux A, Poirier O, et al. Synergistic effects of angiotensin-converting enzyme and angiotensin-II type 1 receptor gene polymorphisms on risk of myocardial infarction. Lancet 1994; 344: 910-3.
15. Fatini C, Abbate R, Pepe G, et al. Searching for a better assessment of the individual coronary risk profile. The role of angiotensin-converting enzyme, angiotensin II type 1 receptor and angiotensinogen gene polymorphisms. Eur Heart J 2000; 21: 633-8.
16. Ye S, Dhillon S, Seear R, et al. Epistatic interaction between variations in the angiotensin I converting enzyme and angiotensin II type 1 receptor genes in relation to extent of coronary atherosclerosis. Heart 2003; 89: 1195-9.
17. Statement on sarcoidosis. Joint Statement of the American Thoracic Society (ATS), the European Respiratory Society (ERS) and the World Association of Sarcoidosis and Other Granulomatous Disorders (WASOG) adopted by the ATS Board of Directors and by the ERS Executive Committee, February 1999. Am J Respir Crit Care Med 1999; 160: 736-55.
18. Rigat B, Hubert C, Corvol P, Soubrier F. PCR detection of the insertion/ deletion polymorphism of the human angiotensin converting enzyme gene (DCP1) (dipeptidyl carboxypeptidase 1). Nucleic Acids Res 1992; 20: 1433.
19. Biller H, Zissel G, Ruprecht B, Nauck M, Busse Grawitz A, Muller-Quernheim J. Genotype-corrected reference values for serum angiotensin-converting enzyme. Eur Respir J 2006; 28: 1085-90.
20. Shanmugam V, Sell KW, Saha BK: Mistyping ACE heterozygotes. PCR Methods Appl 1993; 3: 120-1.
21. Narain Y, Yip A, Murphy T, et al. The ACE gene and Alzheimer's disease susceptibility. J Med Genet 2000; 37: 695-7.
22. Lindpaintner K, Pfeffer MA, Kreutz R, et al. A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ischemic heart disease. N Engl J Med 1995; 332: 706-11.
23. Berge KE, Bakken A, Bohn M, Erikssen J, Berg K. A DNA polymorphism at the angiotensin II type 1 receptor (AT1R) locus and myocardial infarction. Clin Genet 1997; 52: 71-6.
24. Bonnardeaux A, Davies E, Jeunemaitre X, et al. Angiotensin II type 1 receptor gene polymorphisms in human essential hypertension. Hypertension 1994; 24: 63-9.
25. Koyama S, Sato E, Nomura H, et al. Monocyte chemotactic factors released from type II AEC-II-like cells in response to TNF-alpha and IL-1alpha. Eur Respir J 1999;13: 820-8.