메뉴 건너뛰기




Volumn 6, Issue 2, 2010, Pages

Arterivirus Nsp1 modulates the accumulation of minus-strand templates to control the relative abundance of viral mRNAs

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CYSTEINE; CYSTEINE PROTEINASE; HISTIDINE; MESSENGER RNA; NONSTRUCTURAL PROTEIN 1; NONSTRUCTURAL PROTEIN 2; NONSTRUCTURAL PROTEIN 4; RNA DIRECTED RNA POLYMERASE; SERINE PROTEINASE; VIRUS ENVELOPE PROTEIN; VIRUS GLYCOPROTEIN; VIRUS RNA;

EID: 77649247357     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000772     Document Type: Article
Times cited : (54)

References (55)
  • 1
    • 0034691523 scopus 로고    scopus 로고
    • Synthesis of subgenomic RNAs by positive-strand RNA viruses
    • Miller WA, Koev G (2000) Synthesis of subgenomic RNAs by positive-strand RNA viruses. Virology 273: 1-8.
    • (2000) Virology , vol.273 , pp. 1-8
    • Miller, W.A.1    Koev, G.2
  • 2
    • 67349158649 scopus 로고    scopus 로고
    • Coronaviruses post-SARS: Update on replication and pathogenesis
    • Perlman S, Netland J (2009) Coronaviruses post-SARS: update on replication and pathogenesis. Nat Rev Microbiol 7: 439-450.
    • (2009) Nat Rev Microbiol , vol.7 , pp. 439-450
    • Perlman, S.1    Netland, J.2
  • 4
    • 0033799819 scopus 로고    scopus 로고
    • Molenkamp R, van Tol H, Rozier BCD, van der Meer Y, SpaanWJM, Snijder EJ (2000) The arterivirus replicase is the only viral protein required for genome replication and subgenomic mRNA transcription. J Gen Virol 81: 2491-2496.
    • Molenkamp R, van Tol H, Rozier BCD, van der Meer Y, SpaanWJM, Snijder EJ (2000) The arterivirus replicase is the only viral protein required for genome replication and subgenomic mRNA transcription. J Gen Virol 81: 2491-2496.
  • 5
    • 0029444973 scopus 로고
    • Coronaviruses use discontinuous extension for synthesis of subgenome-length negative strands
    • Sawicki SG, Sawicki DL (1995) Coronaviruses use discontinuous extension for synthesis of subgenome-length negative strands. Adv ExpMed Biol 380: 499-506.
    • (1995) Adv ExpMed Biol , vol.380 , pp. 499-506
    • Sawicki, S.G.1    Sawicki, D.L.2
  • 6
    • 0037126614 scopus 로고    scopus 로고
    • Sequence requirements for RNA strand transfer during nidovirus discontinuous subgenomic RNA synthesis
    • Pasternak AO, van den Born E, Spaan WJM, Snijder EJ (2001) Sequence requirements for RNA strand transfer during nidovirus discontinuous subgenomic RNA synthesis. EMBO J 20: 7220-7228.
    • (2001) EMBO J , vol.20 , pp. 7220-7228
    • Pasternak, A.O.1    van den Born, E.2    Spaan, W.J.M.3    Snijder, E.J.4
  • 7
    • 0032718485 scopus 로고    scopus 로고
    • Arterivirus discontinuous mRNA transcription is guided by base pairing between sense and antisense transcription-regulating sequences
    • van Marle G, Dobbe JC, Gultyaev AP, Luytjes W, Spaan WJM, Snijder EJ (1999) Arterivirus discontinuous mRNA transcription is guided by base pairing between sense and antisense transcription-regulating sequences. Proc Natl Acad Sci U S A 96: 12056-12061.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 12056-12061
    • van Marle, G.1    Dobbe, J.C.2    Gultyaev, A.P.3    Luytjes, W.4    Spaan, W.J.M.5    Snijder, E.J.6
  • 8
    • 0347319103 scopus 로고    scopus 로고
    • Sequence motifs involved in the regulation of discontinuous coronavirus subgenomic RNA synthesis
    • Zuniga S, Sola I, Alonso S, Enjuanes L (2004) Sequence motifs involved in the regulation of discontinuous coronavirus subgenomic RNA synthesis. J Virol 78: 980-994.
    • (2004) J Virol , vol.78 , pp. 980-994
    • Zuniga, S.1    Sola, I.2    Alonso, S.3    Enjuanes, L.4
  • 9
    • 33744789955 scopus 로고    scopus 로고
    • Nidovirus transcription: How to make sense. . . ?
    • Pasternak AO, Spaan WJ, Snijder EJ (2006) Nidovirus transcription: how to make sense. . . ? J Gen Virol 87: 1403-1421.
    • (2006) J Gen Virol , vol.87 , pp. 1403-1421
    • Pasternak, A.O.1    Spaan, W.J.2    Snijder, E.J.3
  • 10
    • 33845750075 scopus 로고    scopus 로고
    • A contemporary view of coronavirus transcription
    • Sawicki SG, Sawicki DL, Siddell SG (2007) A contemporary view of coronavirus transcription. J Virol 81: 20-29.
    • (2007) J Virol , vol.81 , pp. 20-29
    • Sawicki, S.G.1    Sawicki, D.L.2    Siddell, S.G.3
  • 11
    • 18144393022 scopus 로고    scopus 로고
    • Discontinuous subgenomic RNA synthesis in arteriviruses is guided by an RNA hairpin structure located in the genomic leader region
    • van den Born E, Posthuma CC, Gultyaev AP, Snijder EJ (2005) Discontinuous subgenomic RNA synthesis in arteriviruses is guided by an RNA hairpin structure located in the genomic leader region. J Virol 79: 6312-6324.
    • (2005) J Virol , vol.79 , pp. 6312-6324
    • van den Born, E.1    Posthuma, C.C.2    Gultyaev, A.P.3    Snijder, E.J.4
  • 12
    • 0028840838 scopus 로고
    • Equine arteritis virus subgenomic RNA transcription: UV inactivation and translation inhibition studies
    • den Boon JA, Spaan WJM, Snijder EJ (1995) Equine arteritis virus subgenomic RNA transcription: UV inactivation and translation inhibition studies. Virology 213: 364-372.
    • (1995) Virology , vol.213 , pp. 364-372
    • den Boon, J.A.1    Spaan, W.J.M.2    Snijder, E.J.3
  • 13
    • 0035852649 scopus 로고    scopus 로고
    • A zinc finger-containing papain-like protease couples subgenomic mRNA synthesis to genome translation in a positive-stranded RNA virus
    • Tijms MA, van Dinten LC, Gorbalenya AE, Snijder EJ (2001) A zinc finger-containing papain-like protease couples subgenomic mRNA synthesis to genome translation in a positive-stranded RNA virus. Proc Natl Acad Sci U S A 98: 1889-1894.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 1889-1894
    • Tijms, M.A.1    van Dinten, L.C.2    Gorbalenya, A.E.3    Snijder, E.J.4
  • 14
    • 34648833261 scopus 로고    scopus 로고
    • Arterivirus subgenomic mRNA synthesis and virion biogenesis depend on the multifunctional nsp1 autoprotease
    • Tijms MA, Nedialkova DD, Zevenhoven-Dobbe JC, Gorbalenya AE, Snijder EJ (2007) Arterivirus subgenomic mRNA synthesis and virion biogenesis depend on the multifunctional nsp1 autoprotease. J Virol 81: 10496-10505.
    • (2007) J Virol , vol.81 , pp. 10496-10505
    • Tijms, M.A.1    Nedialkova, D.D.2    Zevenhoven-Dobbe, J.C.3    Gorbalenya, A.E.4    Snijder, E.J.5
  • 15
    • 0029074522 scopus 로고
    • Processing and evolution of the N-terminal region of the arterivirus replicase ORF1a protein - identification of two papainlike cysteine proteases
    • den Boon JA, Faaberg KS, Meulenberg JJM, Wassenaar ALM, Plagemann PGW, Gorbalenya AE, Snijder EJ (1995) Processing and evolution of the N-terminal region of the arterivirus replicase ORF1a protein - identification of two papainlike cysteine proteases. J Virol 69: 4500-4505.
    • (1995) J Virol , vol.69 , pp. 4500-4505
    • den Boon, J.A.1    Faaberg, K.S.2    Meulenberg, J.J.M.3    Wassenaar, A.L.M.4    Plagemann, P.G.W.5    Gorbalenya, A.E.6    Snijder, E.J.7
  • 16
    • 70350328704 scopus 로고    scopus 로고
    • Crystal structure of porcine reproductive and respiratory syndrome virus (PRRSV) leader protease nsp1α
    • Sun Y, Xue F, Guo Y, Ma M, Hao N, Zhang XC, Lou Z, Li X, Rao Z (2009) Crystal structure of porcine reproductive and respiratory syndrome virus (PRRSV) leader protease nsp1α. J Virol 83: 10931-40.
    • (2009) J Virol , vol.83 , pp. 10931-10940
    • Sun, Y.1    Xue, F.2    Guo, Y.3    Ma, M.4    Hao, N.5    Zhang, X.C.6    Lou, Z.7    Li, X.8    Rao, Z.9
  • 17
    • 42449116994 scopus 로고    scopus 로고
    • Formation of the arterivirus replication/transcription complex: A key role for nonstructural protein 3 in the remodeling of intracellular membranes
    • Posthuma CC, Pedersen KW, Lu Z, Joosten RG, Roos N, Zevenhoven-Dobbe JC, Snijder EJ (2008) Formation of the arterivirus replication/transcription complex: a key role for nonstructural protein 3 in the remodeling of intracellular membranes. J Virol 82: 4480-4491.
    • (2008) J Virol , vol.82 , pp. 4480-4491
    • Posthuma, C.C.1    Pedersen, K.W.2    Lu, Z.3    Joosten, R.G.4    Roos, N.5    Zevenhoven-Dobbe, J.C.6    Snijder, E.J.7
  • 18
    • 33751405956 scopus 로고    scopus 로고
    • Proteolytic maturation of replicase polyprotein pp1a by the nsp4 main proteinase is essential for equine arteritis virus replication and includes internal cleavage of nsp7
    • van Aken D, Zevenhoven-Dobbe J, Gorbalenya AE, Snijder EJ (2006) Proteolytic maturation of replicase polyprotein pp1a by the nsp4 main proteinase is essential for equine arteritis virus replication and includes internal cleavage of nsp7. J Gen Virol 87: 3473-3482.
    • (2006) J Gen Virol , vol.87 , pp. 3473-3482
    • van Aken, D.1    Zevenhoven-Dobbe, J.2    Gorbalenya, A.E.3    Snijder, E.J.4
  • 19
    • 0032982143 scopus 로고    scopus 로고
    • Proteolytic processing of the open reading frame 1b-encoded part of arterivirus replicase is mediated by nsp4 serine protease and is essential for virus replication
    • van Dinten LC, Rensen S, Gorbalenya AE, Snijder EJ (1999) Proteolytic processing of the open reading frame 1b-encoded part of arterivirus replicase is mediated by nsp4 serine protease and is essential for virus replication. J Virol 73: 2027-2037.
    • (1999) J Virol , vol.73 , pp. 2027-2037
    • van Dinten, L.C.1    Rensen, S.2    Gorbalenya, A.E.3    Snijder, E.J.4
  • 20
    • 0024403619 scopus 로고
    • High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis
    • Cunningham BC, Wells JA (1989) High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis. Science 244: 1081-1085.
    • (1989) Science , vol.244 , pp. 1081-1085
    • Cunningham, B.C.1    Wells, J.A.2
  • 21
    • 0026737363 scopus 로고
    • Systematic mutational analysis of the yeast ACT1 gene
    • Wertman KF, Drubin DG, Botstein D (1992) Systematic mutational analysis of the yeast ACT1 gene. Genetics 132: 337-350.
    • (1992) Genetics , vol.132 , pp. 337-350
    • Wertman, K.F.1    Drubin, D.G.2    Botstein, D.3
  • 22
    • 0025969881 scopus 로고
    • Suggestions for "safe" residue substitutions in site-directed mutagenesis
    • Bordo D, Argos P (1991) Suggestions for "safe" residue substitutions in site-directed mutagenesis. J Mol Biol 217: 721-729.
    • (1991) J Mol Biol , vol.217 , pp. 721-729
    • Bordo, D.1    Argos, P.2
  • 23
    • 0033994692 scopus 로고    scopus 로고
    • Subgenomic negative-strand RNA function during mouse hepatitis virus infection
    • Baric RS, Yount B (2000) Subgenomic negative-strand RNA function during mouse hepatitis virus infection. J Virol 74: 4039-4046.
    • (2000) J Virol , vol.74 , pp. 4039-4046
    • Baric, R.S.1    Yount, B.2
  • 24
    • 0035143741 scopus 로고    scopus 로고
    • The RNA structures engaged in replication and transcription of the A59 strain of mouse hepatitis virus
    • Sawicki D, Wang T, Sawicki S (2001) The RNA structures engaged in replication and transcription of the A59 strain of mouse hepatitis virus. J Gen Virol 82: 385-396.
    • (2001) J Gen Virol , vol.82 , pp. 385-396
    • Sawicki, D.1    Wang, T.2    Sawicki, S.3
  • 25
    • 0033031789 scopus 로고    scopus 로고
    • Characterization of an equine arteritis virus replicase mutant defective in subgenomic mRNA synthesis
    • van Marle G, van Dinten LC, Spaan WJM, Luytjes W, Snijder EJ (1999) Characterization of an equine arteritis virus replicase mutant defective in subgenomic mRNA synthesis. J Virol 73: 5274-5281.
    • (1999) J Virol , vol.73 , pp. 5274-5281
    • van Marle, G.1    van Dinten, L.C.2    Spaan, W.J.M.3    Luytjes, W.4    Snijder, E.J.5
  • 27
    • 0037213301 scopus 로고    scopus 로고
    • Heterodimerization of the two major envelope proteins is essential for arterivirus infectivity
    • Snijder EJ, Dobbe JC, Spaan WJM (2003) Heterodimerization of the two major envelope proteins is essential for arterivirus infectivity. J Virol 77: 97-104.
    • (2003) J Virol , vol.77 , pp. 97-104
    • Snijder, E.J.1    Dobbe, J.C.2    Spaan, W.J.M.3
  • 28
    • 0029037521 scopus 로고
    • The two major envelope proteins of equine arteritis virus associate into disulfidelinked heterodimers
    • de Vries AA, Post SM, Raamsman MJ, Horzinek MC, Rottier PJ (1995) The two major envelope proteins of equine arteritis virus associate into disulfidelinked heterodimers. J Virol 69: 4668-4674.
    • (1995) J Virol , vol.69 , pp. 4668-4674
    • de Vries, A.A.1    Post, S.M.2    Raamsman, M.J.3    Horzinek, M.C.4    Rottier, P.J.5
  • 29
    • 0037738465 scopus 로고    scopus 로고
    • Formation of disulfide-linked complexes between the three minor envelope glycoproteins (GP2b, GP3, and GP4) of equine arteritis virus
    • Wieringa R, de Vries AA, Rottier PJ (2003) Formation of disulfide-linked complexes between the three minor envelope glycoproteins (GP2b, GP3, and GP4) of equine arteritis virus. J Virol 77: 6216-6226.
    • (2003) J Virol , vol.77 , pp. 6216-6226
    • Wieringa, R.1    de Vries, A.A.2    Rottier, P.J.3
  • 30
    • 0026475757 scopus 로고
    • The 5′ end of the equine arteritis virus replicase gene encodes a papain-like cysteine protease
    • Snijder EJ, Wassenaar ALM, Spaan WJM (1992) The 5′ end of the equine arteritis virus replicase gene encodes a papain-like cysteine protease. J Virol 66: 7040-7048.
    • (1992) J Virol , vol.66 , pp. 7040-7048
    • Snijder, E.J.1    Wassenaar, A.L.M.2    Spaan, W.J.M.3
  • 31
    • 34547734952 scopus 로고    scopus 로고
    • Hepatitis C virus p7 and NS2 proteins are essential for production of infectious virus
    • Jones CT, Murray CL, Eastman DK, Tassello J, Rice CM (2007) Hepatitis C virus p7 and NS2 proteins are essential for production of infectious virus. J Virol 81: 8374-8383.
    • (2007) J Virol , vol.81 , pp. 8374-8383
    • Jones, C.T.1    Murray, C.L.2    Eastman, D.K.3    Tassello, J.4    Rice, C.M.5
  • 32
    • 0037370719 scopus 로고    scopus 로고
    • Leader proteinase of beet yellows virus functions in long-distance transport
    • Peng CW, Napuli AJ, Dolja VV (2003) Leader proteinase of beet yellows virus functions in long-distance transport. J Virol 77: 2843-2849.
    • (2003) J Virol , vol.77 , pp. 2843-2849
    • Peng, C.W.1    Napuli, A.J.2    Dolja, V.V.3
  • 33
    • 0036211003 scopus 로고    scopus 로고
    • Nuclear localization of nonstructural protein 1 and nucleocapsid protein of equine arteritis virus
    • Tijms MA, van der Meer Y, Snijder EJ (2002) Nuclear localization of nonstructural protein 1 and nucleocapsid protein of equine arteritis virus. J Genl Virol 83: 795-800.
    • (2002) J Genl Virol , vol.83 , pp. 795-800
    • Tijms, M.A.1    van der Meer, Y.2    Snijder, E.J.3
  • 34
    • 0024411889 scopus 로고
    • Characterization of an efficient coronavirus ribosomal frameshifting signal: Requirement for an RNA pseudoknot
    • Brierley I, Digard P, Inglis SC (1989) Characterization of an efficient coronavirus ribosomal frameshifting signal: requirement for an RNA pseudoknot. Cell 57: 537-547.
    • (1989) Cell , vol.57 , pp. 537-547
    • Brierley, I.1    Digard, P.2    Inglis, S.C.3
  • 35
    • 0030856299 scopus 로고    scopus 로고
    • Alternative proteolytic processing of the arterivirus replicase ORF1a polyprotein: Evidence that NSP2 acts as a cofactor for the NSP4 serine protease
    • Wassenaar ALM, Spaan WJM, Gorbalenya AE, Snijder EJ (1997) Alternative proteolytic processing of the arterivirus replicase ORF1a polyprotein: evidence that NSP2 acts as a cofactor for the NSP4 serine protease. J Virol 71: 9313-9322.
    • (1997) J Virol , vol.71 , pp. 9313-9322
    • Wassenaar, A.L.M.1    Spaan, W.J.M.2    Gorbalenya, A.E.3    Snijder, E.J.4
  • 36
    • 3242701315 scopus 로고    scopus 로고
    • Regulation of relative abundance of arterivirus subgenomic mRNAs
    • Pasternak AO, Spaan WJM, Snijder EJ (2004) Regulation of relative abundance of arterivirus subgenomic mRNAs. J Virol 78: 8102-8113.
    • (2004) J Virol , vol.78 , pp. 8102-8113
    • Pasternak, A.O.1    Spaan, W.J.M.2    Snijder, E.J.3
  • 37
    • 47749135896 scopus 로고    scopus 로고
    • The in vitro RNA synthesizing activity of the isolated arterivirus replication/transcription complex is dependent on a host factor
    • van Hemert MJ, de Wilde AH, Gorbalenya AE, Snijder EJ (2008) The in vitro RNA synthesizing activity of the isolated arterivirus replication/transcription complex is dependent on a host factor. J Biol Chem 283: 16525-16536.
    • (2008) J Biol Chem , vol.283 , pp. 16525-16536
    • van Hemert, M.J.1    de Wilde, A.H.2    Gorbalenya, A.E.3    Snijder, E.J.4
  • 41
    • 36048969246 scopus 로고    scopus 로고
    • High fidelity of murine hepatitis virus replication is decreased in nsp14 exoribonuclease mutants
    • Eckerle LD, Lu X, Sperry SM, Choi L, Denison MR (2007) High fidelity of murine hepatitis virus replication is decreased in nsp14 exoribonuclease mutants. J Virol 81: 12135-12144.
    • (2007) J Virol , vol.81 , pp. 12135-12144
    • Eckerle, L.D.1    Lu, X.2    Sperry, S.M.3    Choi, L.4    Denison, M.R.5
  • 43
    • 62549159638 scopus 로고    scopus 로고
    • Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase
    • Chen Y, Cai H, Pan J, Xiang N, Tien P, Ahola T, Guo D (2009) Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase. Proc Natl Acad Sci U S A 106: 3484-3489.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 3484-3489
    • Chen, Y.1    Cai, H.2    Pan, J.3    Xiang, N.4    Tien, P.5    Ahola, T.6    Guo, D.7
  • 44
    • 37149001670 scopus 로고    scopus 로고
    • Uncoupling RNA virus replication from transcription via the polymerase: Functional and evolutionary insights
    • Wu B, White KA (2007) Uncoupling RNA virus replication from transcription via the polymerase: functional and evolutionary insights. EMBO J 26: 5120-5130.
    • (2007) EMBO J , vol.26 , pp. 5120-5130
    • Wu, B.1    White, K.A.2
  • 45
    • 0031017109 scopus 로고    scopus 로고
    • An infectious arterivirus cDNA clone: Identification of a replicase point mutation that abolishes discontinuous mRNA transcription
    • van Dinten LC, den Boon JA, Wassenaar ALM, Spaan WJM, Snijder EJ (1997) An infectious arterivirus cDNA clone: Identification of a replicase point mutation that abolishes discontinuous mRNA transcription. Proc Natl Acad Sci U S A 94: 991-996.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 991-996
    • van Dinten, L.C.1    den Boon, J.A.2    Wassenaar, A.L.M.3    Spaan, W.J.M.4    Snijder, E.J.5
  • 46
    • 0025643362 scopus 로고
    • A general method for rapid site-directed mutagenesis using the polymerase chain reaction
    • Landt O, Grunert HP, Hahn U (1990) A general method for rapid site-directed mutagenesis using the polymerase chain reaction. Gene 96: 125-128.
    • (1990) Gene , vol.96 , pp. 125-128
    • Landt, O.1    Grunert, H.P.2    Hahn, U.3
  • 47
    • 1242318840 scopus 로고    scopus 로고
    • Secondary structure and function of the 5′-proximal region of the equine arteritis virus RNA genome
    • van den Born E, Gultyaev AP, Snijder EJ (2004) Secondary structure and function of the 5′-proximal region of the equine arteritis virus RNA genome. RNA 10: 424-437.
    • (2004) RNA , vol.10 , pp. 424-437
    • van den Born, E.1    Gultyaev, A.P.2    Snijder, E.J.3
  • 48
    • 0031879009 scopus 로고    scopus 로고
    • ORF1a-encoded replicase subunits are involved in the membrane association of the arterivirus replication complex
    • van der Meer Y, van Tol H, Locker JK, Snijder EJ (1998) ORF1a-encoded replicase subunits are involved in the membrane association of the arterivirus replication complex. J Virol 72: 6689-6698.
    • (1998) J Virol , vol.72 , pp. 6689-6698
    • van der Meer, Y.1    van Tol, H.2    Locker, J.K.3    Snijder, E.J.4
  • 49
    • 0033017866 scopus 로고    scopus 로고
    • Open reading frame 1a-encoded subunits of the arterivirus replicase induce endoplasmic reticulum-derived double-membrane vesicles which carry the viral replication complex
    • Pedersen KW, van der Meer Y, Roos N, Snijder EJ (1999) Open reading frame 1a-encoded subunits of the arterivirus replicase induce endoplasmic reticulum-derived double-membrane vesicles which carry the viral replication complex. J Virol 73: 2016-2026.
    • (1999) J Virol , vol.73 , pp. 2016-2026
    • Pedersen, K.W.1    van der Meer, Y.2    Roos, N.3    Snijder, E.J.4
  • 51
    • 0025939363 scopus 로고
    • Improved method for detecting poliovirus negative strands used to demonstrate specificity of positive-strand encapsidation and the ratio of positive to negative strands in infected cells
    • Novak JE, Kirkegaard K (1991) Improved method for detecting poliovirus negative strands used to demonstrate specificity of positive-strand encapsidation and the ratio of positive to negative strands in infected cells. J Virol 65: 3384-3387.
    • (1991) J Virol , vol.65 , pp. 3384-3387
    • Novak, J.E.1    Kirkegaard, K.2
  • 53
    • 33745604908 scopus 로고    scopus 로고
    • Transcriptional profiling of acute cytopathic murine hepatitis virus infection in fibroblast-like cells
    • Versteeg GA, Slobodskaya O, Spaan WJ (2006) Transcriptional profiling of acute cytopathic murine hepatitis virus infection in fibroblast-like cells. J Gen Virol 87: 1961-1975.
    • (2006) J Gen Virol , vol.87 , pp. 1961-1975
    • Versteeg, G.A.1    Slobodskaya, O.2    Spaan, W.J.3
  • 54
    • 22144458748 scopus 로고    scopus 로고
    • Diagnosis of human metapneumovirus and rhinovirus in patients with respiratory tract infections by an internally controlled multiplex real-time RNA PCR
    • Scheltinga SA, Templeton KE, Beersma MF, Claas EC (2005) Diagnosis of human metapneumovirus and rhinovirus in patients with respiratory tract infections by an internally controlled multiplex real-time RNA PCR. J Clin Virol 33: 306-311.
    • (2005) J Clin Virol , vol.33 , pp. 306-311
    • Scheltinga, S.A.1    Templeton, K.E.2    Beersma, M.F.3    Claas, E.C.4
  • 55
    • 0029974217 scopus 로고    scopus 로고
    • Equine arteritis virus subgenomic mRNA synthesis: Analysis of leader-body junctions and replicative-form RNAs
    • den Boon JA, Kleijnen MF, Spaan WJM, Snijder EJ (1996) Equine arteritis virus subgenomic mRNA synthesis: analysis of leader-body junctions and replicative-form RNAs. J Virol 70: 4291-4298.
    • (1996) J Virol , vol.70 , pp. 4291-4298
    • den Boon, J.A.1    Kleijnen, M.F.2    Spaan, W.J.M.3    Snijder, E.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.