High dose of ethanol decreases total spectral power density in seizures induced by D,L-homocysteine thiolactone in adult rats

General Physiology and Biophysics

Volumn 28, Issue SPECIAL ISSUES, 2009, Pages 25-32

  Rašić Marković, Aleksandra ^a   Djuric, Dragan ^a   Hrnčić, Dragan ^a   Lončar Stevanović, Helena ^a   Vučević, Danijela ^a   Mladenović, Dušan ^a   Brkić, Predrag ^a   Djuro, Macut ^b   Stanojević, Ivana ^c   Stanojlović, Olivera ^a  

^a UNIVERSITY OF BELGRADE   (Serbia)

^b CLINICAL CENTER OF SERBIA   (Serbia)

^c UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

D,L homocysteine thiolactone; EEG; Epilepsy; Ethanol

Indexed keywords

ALCOHOL; HOMOCYSTEINE THIOLACTONE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ELECTRIC POTENTIAL; ELECTRODE; ELECTROENCEPHALOGRAM; MALE; NERVE CELL EXCITABILITY; NEUROTOXICITY; NONHUMAN; RAT; SEIZURE; SKULL; SPECTRUM; SPIKE WAVE;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROENCEPHALOGRAPHY; ETHANOL; HOMOCYSTEINE; MALE; RATS; RATS, WISTAR; SEIZURES; TIME FACTORS;

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 77649247137     PISSN: 02315882     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. - current in cultured mouse neurons. J. Pharmac. Exp. Ther. 270, 61-69
2. Brailowsky S., Garcia O. (1990): Ethanol, GABA and epilepsy. Arch. Med. Res. 30, 3-9
3. Chandler L. J., Newsom H., Sumners C., Crews F. (1993): Chronic ethanol exposure potentiates NMDA excitotoxicity in cerebral cortical neurons. J. Neurochem. 60, 1578-1581
4. Coe I. R., Yao L. N., Diamond I., Gordon A. S. (1996): The role of protein kinase C in cellular tolerance to ethanol. J. Biol. Chem. 271, 29468-29472
5. Cohen H. L., Porjesz B., Begleiter H. (1993b): Ethanol-induced alterations in electroencephalographic activity. Electroencephalogr. Clin. Neurophysiol. 86, 368-376
6. Cohen S. M., Martin D., Morrisett R. A., Wilson W. A., Swartzwelder H. S. (1993a): Proconvulsant and anticonvulsant properties of ethanol: studies of electrographic seizures in vitro. Brain Res. 601, 80-87
7. 1 adenosine receptor function in rat cerebellum. Pharmac. Biochem. Behav. 53, 249-255
8. Davis K., Jang-Yen W. (2001): Role of glutamatergic and GABAergic systems in alcoholism. J. Biomed. Sci. 8, 7-19
9. Faingold C. L., Gouemo P., Riaz A. (1998): Ethanol and neurotransmitter interactions - from molecular to integrative effects. Prog. Neurobiol. 55, 509-535
10. Fischer W. (2005): Influence of ethanol on the threshold for electroshock-induced seizures and electrically-evoked hippocampal afterdischarges. J. Neural. Transm. 112, 1149-1163
11. Fischer W., Kittner H. (1998): Influence of ethanol on the pentylenetetrazole-induced kindling in rats. J. Neural. Transm. 105, 1129-1142
12. Folbergová J., Haugvicová R., Mareš P. (2000): Behavioral and metabolic changes in immature rats during seizures induced by homocysteic acid: the protectie effect of NMDA and non-NMDA receptor antagonists. Exp. Neurol. 161, 336-345
13. Folbergrova J. (1997): Anticonvulsant action of both NMDA and non-NMDA receptor antagonists against seizures induced by homocysteine in immature rats. Exp. Neurol. 145, 442-450
14. Hillbom M., Pieninkeroinen I., Leone M. (2003): Seizures in alcohol-dependent patients. CNS Drugs 17, 1013-1030
15. Hoffman P. L., Rabe C. S., Moses F., Tabakoff B. (1989): N-methyl-D-aspartate receptors and ethanol: inhibition of calcium flux and cyclic GMP production. J. Neurochem. 52, 1937-1940
16. Ilian A. B., Gevins A. (2001): Prolonged neurophsiological effects of cumulative wine drinking. Alcohol 25, 137-152
17. Jakubowski H. (2006): Pathophysiological consequences of homocysteine excess. J. Nutr. 136, S1741-1749
18. Kim C. K., Kalynchuk L. E., Pinel J. P., Kippin T. E. (1995): Tolerance to the anticonvulsant and ataxic effects of pentobarbital: effect of an ascending-dose regimen. Pharmacol. Biochem. Behav. 52, 825-829
19. Little H. J. (1999): The contribution of electrophysiology to knowledge of the acute and chronic effects of ethanol. Pharmacol. Ther. 84, 333-353
20. Loscher W. (2002): Current status and future directions in the pharmacotherapy of epilepsy. Trends Pharmacol. Sci. 23, 113-118
21. Lovinger D. M., White G., Weight F. F. (1989): Ethanol inhibits NMDA-activated ion current in hippocampal neurons. Science 243, 1721-1724
22. Lucas S. E., Mendelson J. H., Benedikt R. A., Jones B. (1986): EEG alpha activity increases during transient episodes of ethanol-induced euphoria. Pharmacol. Biochem. Behav. 25, 889-895
23. Marangos P. J., Lofturs T., Weisner J., Lowe T., Rossi E., Browne C. E., Gruber H. E. (1990): Adenosine modulation of homocysteine-induced seizures in mice. Epilepsia 31, 239-246
24. Meldrum B. S. (1994): The role of glutamate in epilepsy and other CNS disorders. Neurology 44, 4-23
25. Pietrzak B., Czarnecka E. (2005): Effect of the combined administration of ethanol and acamprosate on rabbit EEG. Pharmacol. Rep. 57, 61-69
26. Pietrzak B., Czarnecka E. (2006): The effect of combined administration of ethanol and gabapentin on rabbit electroencephalographic activity. Basic Clin. Pharmacol. Toxicol. 99, 383-390
27. Sachdev P. S. (2005): Homocysteine and brain atrophy. Prog. Neuropharmacol. Biol. Psychiatry 29, 1152-1161
28. Sarkisian M. R. (2001): Overview of the current animal models for human seizure and epileptic disorders. Epilepsy Behav. 2, 201-216
29. Sauerland E. K., Harper R. M. (1970): Effects of ethanol on EEG spectra of the intact brain and isolated forebrain. Exp. Neurol. 27, 490-496
30. Scharfman H. E. (2007): The neurobiology of epilepsy. Curr. Neurol. Neurosci. Rep. 4, 348-354
31. Sener U., Zorlu Y., Karaguzel O., Ozdamar O., Coker I., Topbas M. (2006): Effects of common anti-epileptic drug monotherapy on serum levels of homocysteine, vitamin B12, folic acid and vitamin B6. Seizure 15, 79-85
32. Simson P. E., Criswell H. E., Johnson K. B., Hicks R. E., Breese G. R. (1991): Ethanol inhibits NMDA-evoked electrophysiological activity in vivo. J. Pharmacol. Exp. Ther. 257, 225-231
33. Stanojlović O., Živanović D., Šuš ić V. (2000): N-methyl-D-aspartic acid and metaphit-induced audiogenic seizures in rat model of seizure. Pharmacol. Res. 42, 247-253
34. Stanojlović O., Hrnčić D., Rašić A., Lončar-Stevanović H., Djuric D., Šušić V. (2007) Interaction of delta sleep-inducing peptide and valproate on metaphit audiogenic seizure model in rats. Cell Mol. Neurobiol. 27, 923-932
35. Stanojlović O., Rašić-Marković A., Hrnčić D., Sušić V., Macut D., Radosavljević T., Djuric D. (2009): Two types of seizures in homocysteine thiolactone-treated adult rats, behavioral and electroencephalographic study. Cell. Mol. Neurobiol. 29, 329-339
36. Wang Y., Jeng C. H., Lin J. C., Wang J. Y. (1996): Serotonin modulates ethanol-induced depression in cerebellar Purkinje neurons. Alcohol Clin. Exp. Res. 20, 1229-1236
37. Wuerthele S. E., Yasuda R. P., Freed W. J., Hoffer B. J. (1982): The effect of local application of homocysteine on neuronal activity in the central nervous system of the rat. Life Sci. 31, 2683-2691
38. Young G. A., Wolf D. L., Khazan N. (1982): Relationships between blood ethanol levels and ethanol-induced changes in cortical EEG power spectra in the rat. Neuropharmacology 21, 721-723
39. Zhuk O. V., Zinkovsky V. G., Golovenko N. Y. (2001): The pharmacodynamics of anticonvulsant and subconvulsant effects of ethanol in CBA and C57BL/6 mice. Alcohol 23, 23-58
40. Zieminska E., Stafiej A., Lazarewicz J. (2003): Role of group I metabotropic glutamate receptors and NMDA receptors in homocysteine-evoked acute neurodegeneration of cultured cerebellar granule neurons. Neurochem. Int. 43, 481-492